• BMB Reports
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• v.50 no.5
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• pp.263-268
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• 2017

${\beta}$-Agarase cleaves the ${\beta}$-1,4 linkages of agar to produce neoagarooligosaccharides (NAO), which are associated with various physiological functions. However, the immunological functions of NAO are still unclear. In this study, we demonstrated that ${\beta}$-agarase DagA-produced neoagarohexaose (DP6), an NAO product, promoted the maturation of dendritic cells (DCs) by Toll-like receptor 4 (TLR4). DP6 directly and indirectly enhanced the activation of natural killer (NK) cells in a TLR4-dependent manner in vitro and in vivo. Finally, the antitumor activity of DP6 against B16F1 melanoma cells was inhibited in NK cell-depletion systems by using NK-cell depleting antibodies in vivo. Collectively, the results indicated that DP6 augments antitumor immunity against B16F1 melanoma cells via the activation of DC-mediated NK cells in a TLR4-dependent manner. Thus, DP6 is a potential candidate adjuvant that acts as an immune cell modulator for the treatment of melanoma.

• Journal of Digital Contents Society
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• v.19 no.2
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• pp.309-318
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• 2018

We proposed a marketing plan for the performing arts venue using realistic contents(VR, AR, and MR). The venue is a place where the audience can experience the performance directly. The marketing plan of the performance venue is as follows. Firstly, it is a marketing strategy that utilizes an arrangement of venue seats. It is possible to predict for watching a performance at angle and sight in performance venue seats that audience want through VR. This allows the theatre seats to be experienced in advance with the VR contents inducing the reservation of the seats with a high sense of immersion. Secondly, it is a marketing using PR and AD of performing arts through MR in the space with a large transient population. It is possible to promote dynamic promotion utilizing the sense of the presence of performing arts compared with existing static promotion means. Thirdly, it is a marketing strategy that utilizes actor characters in performance. The audience could be interested in the performing arts in advance via a preview of the AR contents of the pamphlet. Fourthly, it is a way to communicate with customers directly by establishing a VR social network to manage venue members. This will help attract an audience to revitalize the theatre venue.

• Journal of Digital Contents Society
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• v.19 no.2
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• pp.251-257
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• 2018

The purpose of this study is to analyze the satisfaction and requirements of users' devices after development of tablet based AAC(Augmentative and Alternatice Communication) application for Android. The purpose of this study is to evaluate the satisfaction and the requirement of tablet - based AAC application, Were assessed using the Korea Assistive Technology Assessment Tool (KAAT). As a result of satisfaction evaluation of tablet-based smart AAC device, all the items including device, service, and everyday life showed positive response satisfying from 5 point scale to more than 4 point scale. However, it was relatively low in the items of effectiveness, manipulation and convenience. Some of the improvements in the application include the enlargement of the symbol sound and the simplicity of symbol editing. The results of the study suggest that continual updates of m Smart AAC applications, the simplicity of symbolic editing, application usage and training should be improved. The satisfaction evaluation results of this study and the feedback of potential users will be the guidelines for improving and complementing the functions of existing smart AAC devices.

• Journal of Digital Contents Society
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• v.16 no.5
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• pp.681-689
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• 2015

This study aims to survey the effectiveness of the international distance learning between Korean and Japanese university students. This research is based on NWCCDL (Namseoul-Waseda Cross-Cultural Distance Learning) project in the spring semester, 2015. This project is the cross-cultural distance learning project between N University in Korea and W University in Japan, and the most important thing of this project is that this project is manipulated through the utilization of ICT. This research consists with two parts: the first is to introduce the NWCCDL project; the participants' information, and the contents and procedure of the on-line chatting program, and BBS(Bulletin Board System) activities. The second is to review on the students' satisfaction for the project and the utilization of ICT in English language education context. The analytic results of the questionnaire includes the students' satisfaction on this project and their reflection on the effectiveness of using ICT in English language classroom of Korea. The results prove that the most of the students are satisfied with the NWCCDL Project in the spring semester, 2015 and the most of the students agree with the fact that the utilization of ICT is very effective in English language education of Korea.

• Journal of Digital Contents Society
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• v.16 no.5
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• pp.849-869
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• 2015

Since South Korean government pushed ahead with decentralization system in 1990s, each local government has developed 'local government's character' so that communication between local residents and between local government and residents could be going well for rural solidarity. Local governments have designed their sole symbolic characters, applied the characters to local specialities and tourist goods, and used the designed characters for the promotion of area. There is no difference between South Korea and Japan in the function of local government's character as above-mentioned details. However, 'Yuru-chara' characters which are designed by local governments in Japan are rising dramatically in the field of Japanese major characters. 'Yuru-chara' characters' name awareness is expanded to the entire area of Japan as well as the designed area. A remarkable difference in how to promote character rather than character design caused such a successful outcome. The local governments in Japan carried out a promotion for local residents in various, friendly, and active ways, utilized local government's character as a way to publicize the image of area, and turned the character into products to bring additional effects. In the above process, there was a remarkable difference between Japan and South Korea. The purpose of this study was to research detail data related to the characters of the local governments in Japan, to analyze the promotion of the characters, and to suggest a strategy for promoting the characters of the local governments in South Korea.

• Journal of Digital Contents Society
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• v.16 no.5
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• pp.783-793
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• 2015

TV display which existed only in house started to show up out of house around us and now it found naturally its place in everywhere like street, bus, subway and elevator. It is called digital signage which showed up through digitalization of sign, that is, sign board and bulletin board. The distinction of digital sign from existing signs is that the latter one should go through physical process like removal after installation every time its contents are changed but the former one can produce its various outputs flexibly once it is installed. Also existing sign may be static image or 2 or 3 pieces of image to express simple motion while digital sign can contain multi media contents luxurious in design and motion. This paper confined the range of contents in digital signage in bus and subway. It needs to analyze characteristics of mass transportation-people of use, consumer by place and time, accommodation environment for consumer etc and arrange planned contents along with time and place. Developments of dedicated contents suitable to those digital signages will harmonize with place and time and promote the realm of digital signage which provides variety of experience to consumer and with which communication is possible and which is distinctive. Furthermore we may expect the birth of smart signage as a new media, in which fun and art are combined.

• Journal of Digital Contents Society
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• v.15 no.1
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• pp.19-27
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• 2014

In order to estimate the life of 2,5 inch HDD which is adopted by PC environment, make the test plan which reflect the failure mode of market, make the test model of accelerated life test which reflect the stress of temperature. after an analysis of the environment of PC using, test procedure was decided that operation was write 50 % and read 50 %, and then access method was sequential 50 % and random 50%. The acceleration life test was executed on condition that temperature was $50^{\circ}C$ and $60^{\circ}C$, performance was 95 % in max performance, test time was 1000 hours. by the test of goodness of fit of anderson-darling of the failure data during test, it was confirmed that the distribution of failure fellow weibull. test for shape and scale was equal, and shape parameter was 0.7177, characteristic life was 429434 hours at normal user condition($30^{\circ}C$) by the analysis of weibull-arrhenius modeling. It made no difference about the statistics when equality test was executed. The activation energy was 0.2775eV. In analyzing between the failure samples of acceleration test and the samples of market return even though there is detail difference about the share of failure mode, the rank of share was almost same. This study suggest the test procedure of acceleration test of 2.5 inch HDD in PC using environment, and help the life estimation at manufacture and user.

• Journal of Korea Society of Industrial Information Systems
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• v.19 no.5
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• pp.81-90
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• 2014

It is an element certainly required for the cost reduction of a company that forward and reverse logistics chain are unified and constitutes a resource closed-loop supply chain (CLSC). In this study, the inventory control which unifies inventory of distribution centers (DCs) of forward logistics and processing center of reverse logistics in the CLSC environment is proposed. The inventory system model for newly-constructed CLSC considers the JIT(Just-In-Time) delivery from the processing center to the manufacturer, including the making of decisions on whether to wait for the arrival of end-of-life products or to back-order necessary products for manufacturer when the supply of end-of-life products at the processing center via the returning center is insufficient for the demands of the manufacturers. The validity of the proposed model was verified using the genetic algorithm (GA). In order that a parameter might investigate the effect which it has on a solution, the simulation was carried out for priGA(priority-based GA) on three kinds of parameter conditions. Moreover, mhGA(modified hybrid GA) to which a parameter is adjusted for every Study on Reducing Logistics Costs and Inventory Control System according to facilities integration in the Closed-Loop Supply Chain Environment generation, the simulation was carried out to a four-kind numerical example.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2007.06a
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• pp.30-30
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• 2007

현재 다양한 종류의 RF 통신 제품이 시장에 등장하면서 제품의 경쟁력 확보에 있어 소형화 정도가 중요한 이슈가 되고 있다. Passive Device는 RF Circuit을 제작할 때 많은 면적을 차지하고 있으며 이를 감소시키기 위해 여러 연구가 진행되고 있다. 가장 효과적인 방법으로 반도체 집적기술로 크기를 줄이는 방법이 있으나, 공정이 비싸고 제작 시간이 오래 걸려 제품개발 시간과 개발비용이 상승하게 된다. 반면에 SoP-L 공정은 PCB 제작에 이용되는 일반적인 재료와 공정을 사용하므로 개발 비용과 시간을 줄일 수 있다. SoP-L의 또 하나 장점은 다종 재료를 다층으로 구성할 수 있다는 점이다. 최근 chip-type의 Device를 PCB 기판 안에 내장하는 방법의 RF Circuit 소형화 연구가 많이 진행되고 있다. 본 연구에서는 SoP-L 공정으로 chip-type 수동소자를 PCB 기판 내에 함몰하여 수동소자회로를 구현, 분석하여 보았다. 수동소자회로는 880 MHz~960 MHz(GSM) 영역과 1.71 GHz~1.88 GHz(DCS) 영역을 나누는 Diplexer를 구성하였다. 1005 size의 chip 6개로 구현한 Diplexer를 표면실장과 함몰공정으로 제작하고 Network Analyzer로 측정하여 비교하였다. chip 표면실장으로 구현된 Diplexer는 GSM에서 최대 0.86 dB의 loss, DCS에서 최대 0.68 dB의 loss가 나타났다. 표면실장과 비교하였을 때 함몰공정의 Diplexer는 GSM 대역에서 약 0.5 dB의 추가 loss가 나타났으며 목표대역에서 0.6 GHz정도 내려갔다. 이 결과를 바탕으로 두 공정 간 차이점을 확인하고, 함몰공정으로 chip-type 수동소자를 사용하였을 때 고려해야 할 점을 분석하였다. 이를 바탕으로 SoP-L 함몰공정의 안정성을 높여서 이것을 이용한 회로의 소형화에 적용이 가능할 것으로 기대한다. 특히 능동소자의 DC Power Control에서 고용량의 수동소자를 이용할 때 집적도를 높일 수 있을 것이다.

• Journal of Digital Convergence
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• v.17 no.1
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• pp.347-356
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• 2019

Recently, the liberalization of industrial control systems has been accompanied by a major change in the structural paradigm of information systems in the public and public sectors, and potential cyber security problems in the future major infrastructure control systems that cannot respond to the level of security of existing information systems. To cope with this, a cyber security evaluation tool that can evaluate security vulnerability in three dimensions against various infrastructure control system environment is needed. However, a cyber security evaluation in the domestic environments does not have the concept of the current security status and satisfy settings of the infrastructure. Also, the most of items in that environments have had short-term inspection themselves which makes a limitation by a technical area. In order to overcome this problems, many researches are needed to apply CSET (Cyber Security Evaluation Tool) which is the US cyber security evaluation tool to the control environment of various domestic infrastructure. In this paper, first, we analyze methods to apply to the major domain through the analysis of various case studies on existing security assessement tools. Finally, we discuss future directions.