• 생명과학회지
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• 제18권12호
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• pp.1739-1744
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• 2008

본 연구는 50 mg/kg의 STZ로 유발된 당뇨쥐에서 단기간 운동과 capsaicin 섭취가 혈중지질, 항산화 효소 및 Akt량에 미치는 영향을 알아보고자 31마리의 흰쥐를 대상으로 실험 하였다. 운동 군과 운동과 capsaicin을 병행한 군에서는 당뇨 유발 일주일 후 부터 15 m/min, 0%의 경사도로 25분간 주5회 2주간 트레드밀 운동을 실시하여 다음과 같은 결과를 얻었다. 혈중 지질 농도는 capsaicin 섭취와 운동을 병행한 군에서 TG는 유의하게 감소하였고, HDL-C는 다른 군에 비해 유의하게 높게 나타났고, ROS는 당뇨군을 제외한 모든 군에서 유의하게 감소하였다. CAT는 capsaicin만 섭취한 군에서 유의하게 증가하였고, SOD은 운동만 처치한 군과 capsaicin만 섭취한 군에서 유의하게 높았으며, GSH는 당뇨군을 제외한 모든 군에서 유의하게 높은 것으로 각각 나타났다. Akt효소는 capsaicin만 섭취한 군, p-Akt는 운동군에서 유의하게 증가하였다.

• 한국산업보건학회지
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• 제6권2호
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• pp.313-321
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• 1996

Our laboratoy has been participated in Proficiency Analytical Testing (PAT) program which is operated by the Americal Industrial Hygiene Association in cooperation with the National Institute for Occupational Safety and Health (NIOSH). The program is designed to assist a laboratory improve its analytical performance by providing samples on a quarterly basis, evaluating the results, and providing reports on how well the laboratory performed. Evaluation of the results reported here covers five rounds of the PAT program (round 121~round 125). The way a laboratory is evaluated by PAT program is as follows: 1) There is no overall proficiency rating given to a laboratory. 2) A proficiency rating is given for each type of analyze (i.e., metals, silica, asbestos, solvents) that a laboratory analyzed. 3) Proficiency is rated acceptable ("A") if Z score lies between -3 and +3, and unacceptable if Z score is either higher than +3 ("H") or lower than -3 ("Lo"). Z score = (reported data - reference value) / standard deviation 4) For a laboratory to be rated proficient it must either have had no outliers over the most recent two rounds or of the samples actually analyzed over the past year (past four rounds), 75 % or more of the analyze sample results must be acceptable. According to the above rating criteria of PAT program, performance of metals including cadmium, lead, chromium and zinc, and asbestos sample analyses were rated acceptable ("A"). For silica analyses, all samples except one out of four samples in round 122 was rated high("H") were acceptable showing 95 % of ing 95 % of acceptance rate (19/20) throughout the rounds. Analyses of organic solvents were done on 52 samples in 9 types including methanol(MOH), 1,1,1-trichloroethane(MCM), tetrachloroethylene(PCE), trichloroethylene(TCE), benzene(BNZ), o-xylene(OXY), toluene(TOL), chloroform(CFM), 1,2-dichloroethane(DCE). All samples analyzed were rated acceptable except 2 samples that were rated high; one out of each four MCM and TCE samples in round 121, and one that was low out of four o-xylene analyses in round 122 indicating 94 % of acceptance rate(49/52) throughout the rounds. According to the laboratory rating criteria, our laboratory is rated proficient so far for all types of contaminants.