• Parasites, Hosts and Diseases
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• v.45 no.4
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• pp.301-306
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• 2007

We attempted to identify parasite DNA in the biliary stones of humans via PCR and DNA sequencing. Genomic DNA was isolated from each of 15 common bile duct (CBD) stones and 5 gallbladder (GB) stones. The patients who had the CBD stones suffered from cholangitis, and the patients with GB stones showed acute cholecystitis, respectively. The 28S and 18S rDNA genes were amplified successfully from 3 and/or 1 common bile duct stone samples, and then cloned and sequenced. The 28S and 18S rDNA sequences were highly conserved among isolates. Identity of the obtained 28S D1 rDNA with that of Clonorchis sinensis was higher than 97.6%, and identity of the 18S rDNA with that of other Ascarididae was 97.9%. Almost no intra-specific variations were detected in the 28S and 18S rDNA with the exception of a few nucleotide variations, i.e., substitution and deletion. These findings suggest that C. sinensis and Ascaris lumbricoides may be related with the biliary stoneformation and development.

• Bulletin of the Korean Chemical Society
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• v.28 no.11
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• pp.2003-2008
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• 2007

The aminolysis of diphenyl thiophosphinic chloride (2) with substituted anilines in acetonitrile at 55.0 oC is investigated kinetically. Kinetic results yield large Hammett ρX (ρnuc = ?3.97) and Bronsted βX (βnuc = 1.40) values. A concerted mechanism involving a partial frontside nucleophilic attack through a hydrogen-bonded, four-center type transition state is proposed on the basis of the primary normal kinetic isotope effects (kH/kD = 1.0-1.1) with deuterated aniline (XC6H4ND2) nucleophiles. The natural bond order charges on P and the degrees of distortion of 42 compounds: chlorophosphates [(R1O)(R2O)P(=O)Cl], chlorothiophosphates [(R1O)(R2O)P(=S)Cl], phosphonochloridates [(R1O)R2P(=O)Cl], phosphonochlorothioates [(R1O)R2P(=S)Cl], chlorophosphinates [R1R2P(=O)Cl], and chlorothiophosphinates [R1R2P(=S)Cl] are calculated at the B3LYP/ 6-311+G(d,p) level in the gas phase.

• Natural Product Sciences
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• v.19 no.3
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• pp.258-262
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• 2013

Three ergosterol derivatives, ergosta-4,6,8(14),22-tetraen-3-one (1), ergosta-7,24(28)-dien-3-ol (2), and 5,8-epidioxyergosta-6,22-dien-3-ol(3) were isolated from the fruit body of Phellinus pini. Their structures were based on spectroscopic methods including IR, MS, and NMR (1D and 2D). These compounds were evaluated for their activity to decrease melanin production in ${\alpha}$-MSH (melanocyte stimulating hormone) activated B16F10 cells. Compound 1, 2, and 3 reduced melanin content in a dose-dependent manner at concentrations of 5~15 uM. They also suppressed the tyrosinase expression of protein and m-RNA level dose dependently by western blot analysis and RT-PCR experiment in B16F10 murine melanoma cells.

• Journal of Sensor Science and Technology
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• v.8 no.2
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• pp.108-114
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• 1999

Surface acoustic wave (SAW) device is very attractive for gas sensor applications because of their small size, low cost, high sensitivity, and good reliability. A dual delay line surface acoustic wave $NO_2$ gas sensors have been designed and fabricated on the $LiTaO_3$ piezoelectric single crystal substrate. The capacitance of the fabricated IDTs was 326.34pF at the frequency of 79.3MHz. The maximum reflection loss of the impedence-matched IDTs was -16.74dB at the frequency of 79.3MHz. The SAW oscillator was constructed and the stable oscillation was obtained by controlling the gain of rf amplifier properly. The oscillation frequency shift of the SAW oscillator to the $NO_2$ gas was 28Hz/ppm.

• Journal of the Korean Society for Precision Engineering
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• v.24 no.4 s.193
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• pp.21-28
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• 2007

• The Proceeding of the Korean Institute of Electromagnetic Engineering and Science
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• v.17 no.4 s.60
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• pp.3-10
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• 2006

한국의 전파연구소와 일본의 정보통신연구기구는 휴대전화와 같은 이동통신기기로부터 방사되는 전자파가 인체에 흡수되는 에너지 정도를 측정하는 전자파 흡수율(SAR) 평가에 대한 오차 연구를 공동으로 수행하고 있다. 본 논문에서는 동종의 SAR 시스템에서 프로브, 교정용 도파관 및 기준 다이폴 안테나를 상호 교체하여 교정하여 프로브의 교정인자를 구하고 유효성 검사를 통하여 교정 오차를 검증하였다. 프로브 교정에 대한 상호 오차는 0.2 dB 이하의 결과를 얻었으며, 유효성 오차는 최대 0.28 dB를 얻었다. 그러나 SAR 외삽 알고리즘이 다를 경우는 최대 0.48 dB의 상대 오차를 보였다.

• Journal of The Korean Society of Agricultural Engineers
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• v.50 no.5
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• pp.3-15
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• 2008

This study aims to simulate the 3 dimensional (3D) model of Keum-man connection canal using geographic information system (GIS) as well as considering design in viewpoint of engineering. The canal connects from Keumkang to Mangyungkang in order to supply fresh water into Saemankeum lake. This study used 3 dimensional spatial planning model (3DSPLAM) process to generate the 3D model, which has not only several planning layers in actual process, but also their corresponding layers in modeling process to simulate 3D space of rural villages. The discharge of the canal is $20m^3/s$ on slope of 1/28,400 in the canal length of 14.2km, which consists of pipe line and open channel. This study surveyed the route of the canal and its surrounding environment for facilities to make images in the 3D graphic model. Besides, the present study developed data set in GIS for geogrphical surface modeling as well as parameters in hydraulic analysis for water surface profile on the canal using HEC-RAS model. From the data set constructed, this study performed analysis of water surface profile with HEC-RAS, generation of digital elevation model (DEM) and 3D objects, design of the canal section and route on DEM in AutoCAD, and 3D canal model and its surrounding 3D space in 3DMAX with virtual reality. The study result showed that the process making 3D canal model tried in this study is very useful to generate computer graphic model with the designed canal on the surface of DEM. The generated 3D canal can be used to assist decision support for the canal policy.

• Electronics and Telecommunications Trends
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• v.28 no.5
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• pp.111-121
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• 2013

인쇄전자(printed electronics) 기술은 인쇄가 가능한 기능성 전자 잉크 소재를 이용하여 초저가격의 프린팅 공정을 통해서 다양한 전자소자를 제작하는 기술로써, 차세대 ICT 기기의 제작에 적합한 전자제품을 생산하는데 적합한 공정기술로 잘 알려져 있다. 현재 인쇄전자의 기술수준은 일부 요소 부품들을 제작하고 간단한 전자회로를 구현하는 수준에 머무르고 있으나, 도체, 반도체, 절연체의 여러 잉크 소재 및 다양한 초미세 인쇄공정 기술의 개발이 진행됨에 따라 향후 폭넓은 분야에 적용될 것으로 기대된다. 이러한 인쇄전자의 관련 기술 중에서 최근 삼차원(3D) 프린팅 기술이 부상하고 있는데, 지난해 Economist에서는 3D 프린팅을 제3차 산업혁명을 가져올 기술 중 하나로 소개했으며, 세계경제포럼(WEF: World Economic Forum)에서는 2013년 10대 유망 기술 중 하나로 선정했다. 올해 초, 미국의 오바마 대통령은 국정연설에서 거의 모든 제품의 생산 방식을 바꿀 수 있는 잠재력을 가진 기술로 3D 프린팅을 언급했고, Optomec에서는 전자소자용 3D 프린팅 기술을 선보였다. 본 논문에서는 최근에 많이 연구되는 모바일용 무선통신소자나 차세대 디스플레이 백플레인용의 인쇄전자 기술과 상품의 모형인 목업(Mock-up)을 제작할때뿐 만 아니라 전자소자 제작에도 적용이 가능한 3D 프린팅 기술에 대하여 논하고자 한다.

• Journal of ILASS-Korea
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• v.10 no.3
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• pp.17-28
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• 2005

The Holographic Particle Velocimetry system can be a promising optical tool for the measurements of three dimensional particle velocities. In this study, diffused illumination holographic system to measure the sizes and 3D velocities of moving particles based on automatic image processing was developed. First of all basic optical systems for pulse laser recording, continuous laser reconstruction, and image acquisition, were constructed. To determine the position of particles in the optical axis, new three auto-focusing parameters(AEP), namely, Correlation Coefficient, Sharpness Index, and Depth Intensity were introduced and verified. The developed system was applied to spray droplets to validate the capability of the system. Three dimensional positions of particles viewed from two sides were decided using AFP and then 3D velocities of Particles were extracted by particle tracking algorithm. Comparison of measurement results of sizes and 3D velocities of particles with those obtained by laser instrument, PDPA, showed good consistency of the developed holographic system.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.28 no.12
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• pp.941-947
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• 2017

This paper reports a fractional-N phase-locked-loop(PLL) frequency synthesizer that is implemented in a $0.35-{\mu}m$ standard CMOS process and generates a quadrature signal for an FRS terminal. The synthesizer consists of a voltage-controlled oscillator(VCO), a charge pump(CP), loop filter(LF), a phase frequency detector(PFD), and a frequency divider. The VCO has been designed with an LC resonant circuit to provide better phase noise and power characteristics, and the CP is designed to be able to adjust the pumping current according to the PFD output. The frequency divider has been designed by a 16-divider pre-scaler and fractional-N divider based on the third delta-sigma modulator($3^{rd}$ DSM). The LF is a third-order RC filter. The measured results show that the proposed device has a dynamic frequency range of 460~510 MHz and -3.86 dBm radio-frequency output power. The phase noise of the output signal is -94.8 dBc/Hz, and the lock-in time is $300{\mu}s$.