• Clinical and Experimental Pediatrics
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• 제56권10호
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• pp.417-423
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• 2013

Vitamin D is an essential component of bone and mineral metabolism; its deficiency causes growth retardation and skeletal deformities in children and osteomalacia and osteoporosis in adults. Hypovitaminosis D (vitamin D insufficiency or deficiency) is observed not only in adults but also in infants, children, and adolescents. Previous studies suggest that sufficient serum vitamin D levels should be maintained in order to enhance normal calcification of the growth plate and bone mineralization. Moreover, emerging evidence supports an association between 25-hydroxyvitamin D (25[OH]D) levels and immune function, respiratory diseases, obesity, metabolic syndrome, insulin resistance, infection, allergy, cancers, and cardiovascular diseases in pediatric and adolescent populations. The risk factors for vitamin D insufficiency or deficiency in the pediatric population are season (winter), insufficient time spent outdoors, ethnicity (non-white), older age, more advanced stage of puberty, obesity, low milk consumption, low socioeconomic status, and female gender. It is recommended that all infants, children, and adolescents have a minimum daily intake of 400 IU ($10{\mu}g$) of vitamin D. Since the vitamin D status of the newborn is highly related to maternal vitamin D levels, optimal vitamin D levels in the mother during pregnancy should be maintained. In conclusion, given the important role of vitamin D in childhood health, more time spent in outdoor activity (for sunlight exposure) and vitamin D supplementation may be necessary for optimal health in infants, children, and adolescents.

• 한국컴퓨터정보학회논문지
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• 제20권5호
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• pp.31-39
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• 2015

방향 가중 그래프의 차수제약 최소신장트리 (degree-constrained minimum spanning tree, d-MST) 문제는 정확한 해를 구하는 다항시간 알고리즘이 존재하지 않아 NP-완전 문제로 알려져 왔다. 따라서 휴리스틱한 근사 알고리즘을 적용하여 최적 해를 구하고 있다. 본 논문은 차수와 사이클을 검증하는 Kruskal 알고리즘으로 d-MST의 초기 해를 구하고, d-MST의 초기 해에 대해 k-opt를 수행하여 최적 해를 구하는 다항시간 알고리즘을 제안하였다. 제안된 알고리즘을 4개의 그래프에 적용한 결과 2-MST까지 최적 해를 구할 수 있었다.

• Food Science and Biotechnology
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• 제17권6호
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• pp.1151-1155
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• 2008

This study aimed to investigate the alterations in plasma antioxidant activity after the consumption of a single oral dose of curcumin, vitamin C, and E administered individually or in combination to (i) assess possible synergies or antagonism between the antioxidants and (ii) determine the optimal composition of the antioxidant mixture such that the duration of action is prolonged to beyond that of individual antioxidants. Each antioxidant was administered to male Sprague-Dawley rats, and blood samples were drawn at different time points up to 180 min to measure the plasma total antioxidant capacity (TAC). Five antioxidant compositions (M1-M5) were evaluated to assess the possible synergies or antagonisms among them and to determine the optimal composition of the antioxidant mixture. Blood samples were collected up to 360 min post-consumption. A single oral dose of individual antioxidants significantly increased the TAC values; however, the time to reach the peak TAC value varied. Among the 5 antioxidant compositions, M2 exhibited the highest and most prolonged antioxidant effect in plasma; this was greater than the proportional sum of the effects of the individual antioxidants in the composition. This result indicates a synergistic interaction among antioxidants in the optimal composition M2.

• International Journal of Precision Engineering and Manufacturing
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• 제3권2호
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• pp.15-21
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• 2002

A control-structure combined optimal design problem is discussed taking a 3-D truss structure as a design object. We use descriptor forms for a controlled object and a generalized plant because the structural parameters appear naturally in these farms. We consider not only minimum weight design problem for structure system, but also suppression problem of the effect of disturbances for control system as the purpose of the design. A numerical example shows the validity of combined optimal design of structure and control systems. We also consider the validity of sensor-actuator collocation for control system design in this paper.

• 한국경영과학회지
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• 제34권2호
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• pp.77-90
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• 2009

Total profit level Increases if a company increase the cost for achieving R&D related goals of equipment productivity enhancement, production cost saving, or for achieving equipment scale target, sales volume goal. But how much money should be invested to achieve a certain level of profit? We formulated the model to set the optimal goal levels to minimize the investment cost under the constraint that certain level of total profit should be guaranteed. This model derived from a case of P steel company. We found that this should be considered in relation with the production sales planning (known as optimal product mix problem) to guarantee the profit. We suggested a nonlinear programming model, 3 valiant form of the p+roduct mix problem. We can find the optimal Investment level for the R&D related goals or sales volume goal, equipment scale target for the P steel company using the model.

• 한국국방경영분석학회지
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• 제17권1호
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• pp.43-60
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• 1991

Consider N queues without arrivals and with m identical servers. All jobs are independent and service requirements of jobs in a queue are i.i.d. random variables. At any time only one server may be assigned to a queue and switching between queues are allowed. A unit cost is imposed per job per unit time. The objective is to minimized the expected total cost. An flow approximation model is considered and an upperbound for the percentage error of best nonswitching policies to an optimal policy is found. It is shown that the best nonswitching policy is not worse than $11\%$ of an optimal policy For the stochastic model, we consider the case in which the service requirements of all jobs are i.i.d. with an exponential distribution. A longest first policy is shown to be optimal and a worst case analysis shows that the nonswitching policy which starts with the longest queues is not worse than $11\%$ of the optimal policy.

• 한국군사과학기술학회지
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• 제9권1호
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• pp.72-79
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• 2006

This study was focused on analyzing mathematical model for optimal allocation of surveillance equipment which is operated on the natural geographical condition, such as DMZ fence area. Optimal allocation algorithm was studied for the equipment to develop the whole surveillance and watch model for the two area as testing. Also 3D visualization program was developed to display and analyze the detecting effect. The results show that our suggested model will be available for enhancing security condition on the watching area.

• 전기의세계
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• 제26권6호
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• pp.48-54
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• 1977

The object of this work is to study the optimal control strategy of constant speed characteristics for a D.C control motor under influence of disturbance. In the course of the analysis, the linearization and time invariance schemes on motor dynamics are presumed throughout under certain prescribed conditions and the performance measure for optimality is assumed to be quadratic in state and the control effort, with the initial and final time specified. When the motor speed is deviated from a stationary operating point by any external disturbance, the optimal continuous feedback control law is investigated by the application of the calculus of variation and realizability of the required control meachanism is suggested. Finally, the comparative study of the speed reasponses of the motor, with and without the optimal control effort is also presented to confirm the obtained results.

• Journal of Magnetics
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• 제18권4호
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• pp.454-459
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• 2013

This paper deals with an optimal angle error reduction method of magnetic position sensor using hall effect elements. The angle detection simulation for the magnetic position sensor is performed by 3 dimensional finite element method and Taguchi method, one of the design of experiments. The magnetic position sensor is required to generate ideal sine and cosine waveforms from its hall effect elements according to rotation angle for precise angle information. However, the output signals are easy to include harmonics due to uneven magnetic field distribution from permanent magnet in the air-gap in the vicinity of hall effect elements. For the Taguchi method, three design parameters related to position of hall effect elements and shape of back yoke are selected. The characteristics of optimal magnetic position sensor are compared with those of original one in terms of simulation as well as experiment. Finally, the performances of the motor adopting original model and optimal model are represented for the purpose of verification of motor performance due to signals from magnetic position sensor.

• 대한전기학회논문지:시스템및제어부문D
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• 제50권10호
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• pp.464-472
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• 2001

This study uses distributed parameter systems as the spatial discretization technique, modelling in lumped parameter systems, and applies fast WALSH transform and the Picard's iteration method to high order partial differential equations and matrix partial differential equations. This thesis presents a new algorithm which usefully exercises the optimal control in the distributed parameter systems. In exercising optimal control of distributed parameter systems, excellent consequences are found without using the existing decentralized control or hierarchical control method. This study will help apply to linear time-varying systems and non-linear systems. Further research on algorithm will be required to solve the problems of convergence in case of numerous applicable intervals.