• THE INTERNATIONAL COMMERCE & LAW REVIEW
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• v.38
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• pp.377-408
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• 2008

Globalization of R&D activities of multinational firms is becoming important in compared with the past, because of increasing globalization of world economy. So, every country tries to attract foreign investment including R&D activities. In this paper, effects of several factors, which determine the scale of foreign subsidiary's R&D activities in local market, are analyzed. Through the review of previous literature, I found that three groups of determinant factors. The first one is the factor which is related to characteristics of local market, such as competitive situation of local market, accessability to research institutions, etc. The second group is the factor which is related to relationship between foreign subsidiary and its mother company. The dominant factors of this group are operation strategy of foreign subsidiary, competitiveness of mother firm, and equity structure of foreign subsidiary. Finally the characteristics of industry affect to the scale of foreign subsidiary's R&D activities. Among these factors, 6 factors are chosen to investigate empirically. For the empirical investigation, 107 foreign subsidiaries among KOITA(Korea Industrial Technology Association)'s list are chosen. Each subsidiary has more than 50% of foreign equity and implement R&D activities in Korea. The results show that sales volume of foreign subsidiary is dominant influencing factor in determining scale of R&D activities in Korean market. And also I found that currently established firms are implementing more R&D activities than old established firms. This is quite interesting finding. However, R&D activities of foreign subsidiary are not vitalized in Korean market. It probably means that Korean government and Korean business partners have to make effort to enhance foreign firms/ R&D activities, because it could contribute technological and economic development of Korean market.

• Proceedings of the KIEE Conference
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• 1987.07b
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• pp.1457-1460
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• 1987

2-D shape matching algorithm is proposed which uses pivot vector and componentwise adaptive convergence factor. It is proved that proposed algorithm has better result than any other algorithm. It is to be expected that this algorithm will work effectively in 3-D shape matching.

• Journal of Microbiology
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• v.38 no.3
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• pp.187-191
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• 2000

A validation study was conducted to determine the efficacy of solvent/Detergent (S/D) inactivation and Q-Sepharose column chromatographic removal of the human immunodeficiency virus (HIV) during the manufacturing of a high purity antihemopilic factor VIII (GreenMono) from human plasma. S/D treatment using the organic solvent, tri (n-butyl) phosphate, and the detergent, Trition X-100, was a robust and effective step in eliminating HIV-1. The HIV-1 titer was reduced from an initial titer of 8.3 log10 TCID50 to undetectable levels within one minute of S/D treatment, HIV-1 was effectively partitioned form factor VIII during Q-Sepharose column chromatography with the log reduction factor of 4.1 . These results strongly assure the safety of GreenMono From HIV.

• Journal of Advanced Marine Engineering and Technology
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• v.15 no.1
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• pp.51-58
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• 1991

Corrosion fatigue test was performed by the use of plane bending fatigue tester in marine environment having various specific resistance from 25(natural sea water) to 5000.ohm.cm. It is in order to investigate the effects of marine environmental factor on the corrosion fatigue fracture of SS41 steel. The main results obtained are as follows; 1. The aspect ratio(b/a) of corner crack growing in natural sea water is lower than that in air. 2. The surface crack growth rate(da/dN) in marine environment is faster than that in air and da/dN delaies with the specific resistance increased. 3. The experimental constant m of paris rule [da/dN=C(${\delta}$K)$^m$] decrease with the specific resistance decreased and the effect of corrosion in proportion to the specific resistance is more sensitive than that of stress intensity factor range(${\delta}$K) under region II. 4. The accelerative factor(${\alpha}$) in marine environment is about 1.1-2.7 and .alpha. is increase under the low region of stress intensity factor range(${\delta}$K). 5. The electrode potential($E_0$) gets less noble potential with the specific resistance decreased.

• Nuclear Engineering and Technology
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• v.38 no.8
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• pp.809-818
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• 2006

The existing experimental data related to the turbulent mixing factor in rod arrays is examined and a new definition of the turbulent mixing factor is introduced to take into account the turbulent mixing of fluids with various Prandtl numbers. The new definition of the mixing factor is based on the eddy diffusivity of energy. With this definition of the mixing factor, it was found that the geometrical parameter, ${\delta}_{ij}/D_h$ correlates the turbulent mixing data better than Sid, which has been used frequently in existing correlations. Based on the experimental data for a highly turbulent condition in square rod arrays, a correlation describing turbulent mixing dependent on the parameter ${\delta}_{ij}/D_h$ has been developed. The correlation is insensitive to the Re number and it takes into account the effect of the turbulent Prandtl number. The proposed correlation predicts a reasonable mixing even at a lower S/d ratio.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.7 no.4
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• pp.681-693
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• 1995

A new set of capillary tube selection charts for R-22 is proposed. The set of charts takes into account of the roughness effect on the mass flow rate. For this purpose, a set of numerical model is developed and a series of experiments is conducted to verify the numerical model. A numerical model is used to calculated the mass flow rate for several sets of tube diameter, length, inlet pressures and degree of subcooling. The outlet of the tube is controlled to be at critical condition. The experimental flow rate is compared with calculated values. The calculated values are consistently less than the experimental ones except for the flow rate range below 40kg/hr. The deviation is within 10---. Based on the nunmerical model and results of experiments, the set of capillary tube selection charts for R-22 is constructed. The set of charts consists of standard capillary tube chart(L=2030mm, d=1.63mm, ${\varepsilon}=2.5{\mu}m$), non -standard flow factor(${\phi}_1$) chart, and non-standard roughness factor(${\phi}_2$) chart. The mass flow rate, flow factor, and the roughness factor are defined respectively as; $\dot{m}={\phi}_1{\phi}_2\dot{m}_{standard}\\{\phi}_1=\frac{\dot{m}(L,\;d,\;\varepsilon_{standard})}{\dot{m}_{standard}(L_{standard},\;d_{standard},\;{\varepsilon}_{standard})}\\{\phi}_2=\frac{\dot{m}(L_{standard},\;d_{standard},\;{\varepsilon})}{\dot{m}_{standard}(L_{standard},\;d_{standard},\;{\varepsilon}_{standard})}$.

• Journal of the Korean Geotechnical Society
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• v.30 no.1
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• pp.49-63
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• 2014

Bearing capacity factor $N_{\gamma}$ and shape factor were studied for rigid strip and circular footings with a rough base on sand by numerical modelling considering the effect of dilation angle. The numerical model was developed with an explicit finite difference code. Loading procedures and interpretation methods were devised in order to shorten the running time while eliminating the exaggeration of the reaction caused by the explicit scheme. Using the Mohr-Coulomb plasticity model with associated (${\psi}={\phi}$) and nonassociated (${\psi}$ < ${\phi}$) flow-rules, the bearing capacity factor $N_{\gamma}$ was evaluated for various combinations of internal friction angles and dilation angles. Bearing capacity factor decreased as the dilation angle was reduced from the associated condition. An equation applicable to typical sands was proposed to evaluate the relative bearing capacity for the nonassociated condition compared to the associated condition on which most bearing capacity factor equations are based. The shape factor for the circular footing varied substantially when the plane-strain effect was taken into account for the strip footing. The numerical results of this study showed closer trends with the previous experimental results when the internal friction angle was increased for the strip footing. Discussions are made on the reason that previous equations for the shape factor give different results and recommendations are made for the appropriate design shape factor.

• Journal of the Earthquake Engineering Society of Korea
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• v.6 no.2
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• pp.29-37
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• 2002

The purpose of this study is to provide a fundamental data of earthquake resistant design through the estimation of the response modification factor and nonlinear displacement for moment resisting reinforced concrete frames by linear and nonlinear static analysis. The analysis models are designed in accordance with AIK code and then, estimated the response modification factor and nonlinear displacement of the buildings. The parameters such as story numbers(10, 20, 30), plan ratios(1:1, 1:2) and analysis types(2D, 3D) of building structure are chosen for use in this study. After comparing the results of linear and nonlinear static analysis, the response modification factor is obtained as the product of four factors: ductility factor, strength factor, damping factor and redundancy factor. The response modification factor are close to 3.5 in case of 2 span, 4.3 in case of 3 span and 5.0 in case 4 or more span models regardless number of stories and plan ratios. The nonlinear displacement is evaluated from the ratio of story drift angle(nonlinear drift/linear drift). The ratio of story drift angle increases as story numbers increase and the value varies from 5.85 to 9.34.

• BMB Reports
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• v.52 no.6
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• pp.391-396
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• 2019

Receptor activator of nuclear factor kappa B ligand (RANKL) expression in osteoblasts is regulated by 1,25-dihydroxyvitamin D3 (1,25D3). CCAAT/enhancer-binding protein beta ($C/EBP{\beta}$) has been proposed to function as a transcription factor and upregulate RANKL expression, but it is still uncertain how $C/EBP{\beta}$ is involved in 1,25D3-induced RANKL expression of osteoblasts. 1,25D3 stimulation increased the expression of RANKL and $C/EBP{\beta}$ genes in osteoblasts and enhanced phosphorylation and stability of these proteins. Moreover, induction of RANKL expression by 1,25D3 in osteoblasts was downregulated upon knockdown of $C/EBP{\beta}$. In contrast, $C/EBP{\beta}$ overexpression directly upregulated RANKL promoter activity and exhibited a synergistic effect on 1,25D3-induced RANKL expression. In particular, 1,25D3 treatment of osteoblasts increased $C/EBP{\beta}$ protein binding to the RANKL promoter. In conclusion, $C/EBP{\beta}$ is required for induction of RANKL by 1,25D3.

• Journal of Korean Ophthalmic Optics Society
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• v.3 no.1
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• pp.189-199
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• 1998

The system for optical tolerances of completion spectacles was made to sum of the accumulated error - the circumstances on composing prescription, the visual-distance, the tilting angle, the losing of a temple, the vertex distance, the axis of toric lens and the sloping of lens etc. It was given by the relation of allowed values size(T) and power(D), $T=T_0e^{-aD}$. Here, $T_0$ is the size of allowed values of plane-lens with power is 0 and ${\alpha}$ is the factor of allowed values. In case of being adopted to new form s tolerance corresponding to RAL 915, for the tolerance is large direction, the factor of allowed values ${\alpha}$ is $0.166(T_0=5.90)$ and for the tolerance is small direction, the factor of allowed values ${\alpha}$ is $0.166(T_0=2.95)$.