• Natural Product Sciences
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• v.5 no.2
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• pp.70-74
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• 1999

In the course of a search for tumor necrosis factor $(TNF)-{\alpha}$ inhibitory compounds from medicinal plants, we identified neolignans, honokiol and magnolol, from the alcoholic extract of Magnolia offcinalis as active inhibitory principles. These compounds dose-dependently inhibited $TNF-{\alpha}$ production without displaying cytotoxicity and their inhibitory activities measured by $IC_{50}$ values were 53.7 and $61.4\;{\mu}M$, respectively.

• Journal of Institute of Control, Robotics and Systems
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• v.9 no.9
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• pp.700-706
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• 2003

This paper presents a 3D last design system that provides the 3-dimensional last data based on the FFD(Free Form Deformation) method. The proposed system utilizes the control points for deformation factor to convert from the 3D point cloud foot data to the 3D point cloud last data. The deformation factor of the FFD is obtained from the conventional last design technique, and constructed on the FFD lattice based on the bottom view and lateral view of the measured 3D point cloud foot data. In addition, the control points of FFD lattice is decided on the anatomical points of foot. The deformed 3D last obtained from the proposed FFD is saved as a 3D dxf foot data. The experimental results demonstrate that the proposed system have the descent 3D last data based on the openGL window.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.8
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• pp.3741-3745
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• 2014

Background: Emerging evidence implicates the platelet-derived growth factor-D (PDGF-D) in many types of human solid tumors. We investigated whether PDGF-D plays an important role in endometrial cancer (EC) in relation to clinicopathologic phenotype, angiogenesis, and patient prognosis. Materials and Methods: We analyzed PDGF-D protein expression by Western blotting in twenty-seven human endometrial cancer tissues, and matched normal endometrial controls collected at the third Affiliated hospital of Sun Yat-sen University during 2012-2013 (n=27). Immunohistochemical staining was performed using a human PDGF-D antibody on the endometrial cancer patients collected in the same facility during January 2001 and October 2013 (n=152). Patients were followed from the time of primary surgery in 2001-2013 until death or last follow-up. We correlated the PDGF-D expression levels with clinicopathologic parameters and prognosis in human endometrial cancer patients. Results: Compared with matched normal endometrial cases, PDGF-D was up-regulated in endometrial cancer. Expression of PDGF-D protein, found in 78% of the cases, was associated with nonendometrioid histologic type (p=0.028), FIGO stage III/IV (p=0.039), >50% solid tumor growth (p=0.048), pelvic LN metastasis (p=0.035) and ER and PR negativity (p=0.04 and 0.002). PDGF-D expression was also significantly associated with expression of VEGF-A (p=0.021). In multivariate analysis, PDGF-D expression proved to be an independent prognostic factor in addition to histologic grade and FIGO stage. Patients with high expression levels of PDGF-D had a significantly poorer overall survival rate compared with patients with no expression. Conclusions: PDGF-D expression is frequently up-regulated in endometrial cancer, and is associated with aggressive features and poor prognosis.

• Journal of Environmental Science International
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• v.18 no.4
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• pp.389-400
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• 2009

In this research, we measured the number of lanes, distance, disposition of apartment that are affecting the road traffic noise to evaluate the current condition of G city's road traffic noise. We decide on a basis regarding an apartment price formation factor, and the apartment current price and the results that compared. To have a point scale, we set the maximum road traffic noise at a 8 lane road for 5 points, give 4 points for a 6 lane road, which has a $2.1{\sim}2.5\;dB(A)$ difference compared to a 8 lane road, give 3 points for a 4 lane road, which has a $5.2{\sim}5.5\;dB(A)$ difference compared to a 8 lane road, and set 2 points for a 2 lane road and lower. If we set the standard floor plan as horizontal and a living room facing the roadside, the horizontal and living room facing the opposite side of the road is 1 point because it differs by 14.1 dB(A), and the vertical is 3 points since the difference is 5.3 dB(A). If we make grades by the distance, making standard the fifth floor with little soundproof effect from apartment to road, we observe a measurement below 2.9 dB(A) at a distance of less than 10 m and 5 dB(A), decreased at a distance of 20 m. Therefore, 4 points were given for less than 10m, 3 points for $10{\sim}20\;m$, 2 points for more than 20 m as we can apply the effect of a decay distance of line sound source and the decrease in noise effects of more than 6 dB(A), 1 point for more than 40m, and 0 points for more that 80 m since it is negligible. 28 apartments got 0 points because there is no effect of road traffic noise from other apartments, and 50 apartments where only the road at one side effect them got $5{\sim}10$ points. 4 apartments (17-2, 6-3, 10-4, 3-3) received over 20 points. 15 cases showed a difference between developer price and resale price, and 11 cases (73%) among them showed the same trend (price increases with a low road traffic noise restriction factor point) with the point of road traffic noise restriction factor. 4 cases demonstrated the opposite trend, showing price increases with a high restriction factor point. Among the 4 cases, case numbers 2,6 and 9 appear to be more affected by the location factor (business district) than the road traffic noise restriction factor, and case number 1 appears to be affected by the building factor (openness and direction).

• Journal of Korean Academy of Nursing
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• v.12 no.1
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• pp.13-24
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• 1982

The main purpose of this study was to investigate attitudes toward mental illness and the mentally ill of psychiatric nurses in Korea and to identify the relationships between the nurses' attitudes and demographic variables. Subjects in this study were 122 psychiatricnurses and 111non-psychiatric nurses in active service at 12 hospitals in Seoul. The insrtument used for measuring attitudes was a questionaire developed by Cohen and Struening (1962) referred to as the“Opinions about Mental illness(OMI) Scale”made up to 51 Likert-type items. The findings of this study indicated hatnurses showed negative attitudetoward mental illness and the mentally ill: Very high on social restrictiveness (factor D), low on Mental Health Ideology (factor C), and Interpersonal Etiology (factor E). Since the high score on Factor A, B and the low score on Factor B, C, E reflect a negative altitudes toward mental illness, this study population related extremely negative attitudes compared to any other surveys. And of the demographic variables that related to their attitudes the education degree and the kind of the hospital in active service showed very significant differences. On the basis of the investigation the findings indicated the followings; 1) Althohg attitudes toward mental illness and the mentally ill of psychiatric nurses were not significant differences from non-psychatric nurses, there was a trend that attitudes of psychaitric nurses did show more negative responses rather than those of non-psychiatric nurses. 2) Demographic variables that relate to their attitudes on the OMI scale were the education degree of the respondent and the kind of their hospital in active service. 3) About attitudes toward mental illness and the mentally ill baccalaureate nursesshowed more positive attitudes in Factor A (Authoritarianism), Factor C (Mental Health Ideology) and Factor D (Social Restrictiveness) than diploma program murses. 4) Nurses in active Service in the private hospital revealed more positive attitudes(A,B,C,D) except Factor (E) than those in the national or public hospital. 5) The ages, duration of work, wanted or unwantedG roup of psychiatric ward and satisfactory level of psychiatric nursing service were non-significant.

• Journal of Fashion Business
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• v.17 no.6
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• pp.141-157
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• 2013

In this study, we analyzed the figure type and lower-body size of Shanghai and Hong Kong adult women in their early twenties using the data obtained from 3D whole body scanners. We also provided concrete information related to women's lower bodies, in terms of crotch width, crotch length, inseam, outseam, slope of waist, etc., among women in Shanghai and Hong Kong. The result may be useful to the Chinese apparel industry when designing trouser pants for adult women. According to the results of the factor analysis for categorizing the body shape of the lower half, 5 factors were obtained: obesity of the lower half factor, height of the lower half factor, length from waist to the crotch factor, factor related to legs, and shape of the abdomen factor. After performing a cluster analysis according to the factor analysis, three clusters were set: Cluster 1 was represented as the lower half growth type, which has a high value in height of the lower half factor and grows in the abdomen part. Cluster 2 was represented as thin legs type, which has a low value in most part compared to the length of leg bones and factors about legs that have high value. Cluster 3 was represented as the obesity type having a high value in the obesity of the lower half factor. Overall, thin legs type achieved a high rate in Shanghai adult women and obesity type received a high rate in adult women living in Hong Kong.

• The Journal of the Korea Contents Association
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• v.12 no.10
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• pp.63-71
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• 2012

Depth understanding is important for stereoscopic and various methods including space design and cognitive science should be taken account in contents production. Among them, human scientific engineering such as human factor needs to be touched. More specifically, when the stereoscopic designer determines a binocular disparity, the viewpoint of the camera has to be matched with that of the audience. In this process, the structural problem by the distortion due to the dichoptic error is happened, Therefore, 3D sweetening process based on geometric re-analysis and human scientific engineering to minimize the visual fatigue is significant. This paper analyzes the inconsistency problems of the viewpoint in stereoscopic images, and we produce the stereoscopic image contents based on human factors.

• Transactions of the Korean Society of Automotive Engineers
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• v.4 no.2
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• pp.69-79
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• 1996

Dynamic stress intensity factors are derives when the crack is propagating with constant velocity under longitudinal shear stress in orthotropic disk plate. General stress fields of crack tip propagating with constant velocity and least square method are used to obtain the dynamic stress intensity factor. The dynamic stress intensity factors of GLV/GTV=1(=isotropic material or transversely isotropic material) which is obtained in out study nearly coincides with Chiang's results when mode Ⅲ stress is applied to boundary of isotropic disk. The D.S.I.F. of mode Ⅲ stress is greater when α(=angle of crack propagation direction with fiber direction) is 90° than that when α is 0°. In case of a/D(a:crack length, D:disk diameter)<0. 58, the faster crack propagation velocity, the less D.S.I.F. but when crack propagation velocity arrive on ghear stress wave velocity, the D.S.I.F. but when crack propagation velocity arrive on shear stress wave velocity, the D.S.I.F. unexpectedly increases and decreases to zero.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.13 no.1
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• pp.74-79
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• 2002

The EM(Engineering Model) VCO(Voltage Controlled Oscillator) is nonlinear designed for LO(Local Oscillator) of Ka-band satellite transponder. The microstripline coupled with dielectric resonator is implemented as a high impedance inverter to improve the phase noise, and the quality factor of resonant circuit can be transferred to active device with the enhanced loaded quality factor. The developed VCO has the oscillating tuning range of 9.7965~9.8032 GHz for the control voltage range of 0~12 V. This VCO requires the DC power of 8 V and 17 mA. The phase noise characteristics are -96.51 dBc/Hz @10 KHz and -116.5 dBc/Hz @100 KHz, respectively. And, the output power of 7.33 dBm is measured.

• Fisheries and Aquatic Sciences
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• v.26 no.3
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• pp.224-233
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• 2023

This research was conducted at Langgur City, Southeast Maluku Regency, Maluku Province, Eastern Indonesia from November 2020 to February 2021 to study biological aspects of roundscads (Decapterus spp.) which consist of species composition, sex ratio, gonad maturation level, size distribution, length-weight relationship and condition factor. Samples were collected at traditional fish market in Langgur City. Fish samples collected at the market were put into cool box and then brought to the laboratory for further examination. Fish samples were identified, separated based on species, dissected to determine their sex and gonad maturation stage and then measured. Totally, there were 290 specimen collected which consist of five species namely Decapterus kurroides, D. macarellus, D. macrosoma, D. muroadsi and D. russelli. Sex ratio between male and female for all species showed 1:1. Gonad maturation level showed that stage I and II have higher percentage than stage III and IV indicates immature fish more dominant compare to mature one. Among five species found, D. macarellus has larger size while the smaller belongs to D. muroadsi. Results of length-weight relationship analysis showed that roundscads inhabiting Southeast Maluku waters have isometric and negative allometric growth pattern with relative condition factor around 1.00.