• Journal of the Korea Institute of Information and Communication Engineering
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• v.5 no.4
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• pp.653-660
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• 2001

In this paper, we designed 2303.15MHz frequency synthesizer for the purpose of the phase noise prediction. For the modeling of phase noise generated in the designed system through introducing the noise-modeling method suggested by Lascari we analyzed a variation of phase noise as according as that of offset frequency. Especially, for the third-order system of the PLL among some kinds of phase noise generated from VCO we analyzed the aspect of 1/f-noise appearing troubles in the low frequency band. Since it is difficult to analyze mathematically 1/f-noise in the third-order system of the PLL, introducing the concept of pseudo-damping factor has made an ease of the access of the 1/f-noise variance. we showed a numerical formula of 1/f-noise variance in the third-order system of the PLL which is compared with that of 1/f-noise variance in the second-order system of the PLL. As a result, In case of txco we found the reduce rapidly along the offset frequency after passed through that phase-noise was -160dBc/Hz before passed through a loop at 10kHz offset frequency and -162.6705dBc/kHz after passed through the loop, -180dBc/Hz at 100kHz offset frequency and -560dBc/kHz after passed through the loop. We can notice that the variance of third-order system more occurs (or the variance of second-order system in connection with noise bandwidth and variance factor of second-order and third-order system.

• Journal of the Korean Institute of Telematics and Electronics D
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• v.36D no.3
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• pp.75-84
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• 1999

Systematic studies for the effect of the linewidth enhancement factor, the confinement factor, the internal loss and the cavity length on the single mode gain difference and the frequency detuning are performed for $\lambda$/4 phase shifted DFB lasers above threshold. The above threshold characteristics are mainly determined by the linewidth enhancement factor, not by the confinement factor or the parameter defined by the product of the linewidth enhancement factor and the confinement factor. The normalized internal loss defined by the product of the internal loss and the cavity length mainly determines the above threshold characteristics compared to that of the internal loss or the cavity length alone. The effect of the cavity length on threshold characteristics is larger than that of the internal loss in the case of the same normalized internal loss. The above threshold characteristics of quantum well lasers are more resistant to the variations of the confinement factor and the normalized internal loss than those of bulk lasers due to the small linewidth enhancement factor.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.31 no.5
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• pp.363-369
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• 2005

Purpose: To determine the role of Insulin-like Growth Factor-I (IGF-I) in the regulation of Vascular Endothelial Growth Factor (VEGF) expression in MG-63 cells and then to find the mechanism b which this regulation occurs. Materials and methods: MG-63 cells were grown to confluence in 60-mm dishes. To determine the effects of IGF-I on expression of VEGF mRNA according to time and concentration, the cells were treated with 10 nM IGF-I, following isolation of total RNA and Northern blot analysis after 1, 2, 4, 8, 12, 24 hours and after 2 hours of treatment with 0.5, 2, 10, 25, 50 nM IGF-I respectively, isolation of total RNA and Northern blot analysis were followed. To determine the mechanism of action of IGF-I, inhibitors such as hydroxyurea $(76.1\;{\mu}g/ml)$, actinomycin D $(2.5\;{\mu}g/ml)$, cycloheximide $(10\;{\mu}g/ml)$ were added 1 hour after treatment of 10 nM IGF-I. Results: 1. the expression of VEGF mRNA was increased with treatment of IGF-I. 2. The expression of VEGF mRNA was increased according to time-and concentration dependent manner of IGF-I. 3. The effect of IGF-I was decreased by hydroxyuera, actinomycin D, but not by cycloheximide. Conclusion: IGF-I regulate the expression of VEGF mRNA in the level of DNA synthesis and transcription. These results could suggest that IGF-I plays an important role in angiogenesis in the process of new bone formation and remodeling.

• Asian-Australasian Journal of Animal Sciences
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• v.10 no.2
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• pp.233-239
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• 1997

A mammary epithelial cell line (MAC-T) established as a model for lactation was utilized to identify and characterize effects of various hormones upon insulin-like growth factor binding protein secretion. Ligand and immunoblot analyses of conditioned media indicated that insulin-like growth factor binding protein-2 was secreted by MAC-T cells. Insulin-like growth factor-I stimulated insulin-like growth factor binding protein-2 secretion in a dose-dependent manner, but prolactin and bovine somatotropin did not alter insulin-like growth factor binding protein-2 secretion. Insulin increased and cortisol decreased insulin-like growth factor binding protein-2 secretion. Effects of insulin-like growth factor-I on insulin-like growth factor binding protein-2 secretion support previous studies using primary cultures of bovine mammary cells and bovine fibroblasts. Effects of cortisol and insulin on insulin-like growth factor binding protein-2 secretion may be explained by changes in protein synthesis. In addition, supraphysiological doses of insulin can cross-react with the insulin-like growth factor-I receptor and stimulate insulin-like growth factor binding protein-2 secretion. MAC-T cells provide a model system to study mechanisms that regulate local insulin-like growth factor-I bioactivity.

• BMB Reports
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• v.45 no.4
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• pp.227-232
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• 2012

In vertebrates, there are two variants of eukaryotic peptide elongation factor 1A (eEF1A; formerly eEF-$1{\alpha}$), eEF1A1 and eEF1A2, which have three well-conserved domains ($D_I$, $D_{II}$, and $D_{III}$). In neurons, eEF1A1 is the embryonic type, which is expressed during embryonic development as well as the first two postnatal weeks. In the present study, EGFP-tagged eEF1A1 truncates were expressed in cortical neurons isolated from rat embryo (E18-19). Live cell images of transfected neurons showed that $D_{III}$-containing EGFP-fusion proteins (EGFP-$D_{III}$, -$D_{II-III}$, -$D_{I-III}$) formed clusters that were confined within somatodendritic domains, while $D_{III}$-missing ones (EGFP-$D_I$, -$D_{II}$, -$D_{I-II}$) and control EGFP were homogeneously dispersed throughout the neuron including axons. In dendrites, EGFP-$D_{III}$ was targeted to the heads of spine- and filopodia-like protrusions, where it was colocalized with $SynGAP{\alpha}$, a postsynaptic marker. Our data indicate that $D_{III}$ of eEF1A1 mediates formation of clusters and localization to spines.

• Journal of Digital Convergence
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• v.11 no.7
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• pp.201-207
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• 2013

The chirp signaling has been mainly used in radar systems due to its good correlation characteristics, and nowadays it is applied to real time locating system(RTLS). The RTLS with chirp signaling was chosen as a standard such as ISO/IEC 24730-5 and IEEE 802.15.4a. In this paper, the performance of a real time locating system with chirp signaling was evaluated and simulated with relative distance error rates. We considered three cases of S/I = -30[dB], -20[dB], and -10[dB] with Rician factor K=10 and K=20. The performance was enhanced with K factor improvement by 25%, 27% and 50% for respective three cases of S/I. As results, in case of S/I < -20[dB], the minimum signal power is required for performance improvement even though the line of sight component is helpful. And also, in case of S/I ${\geq}$ -20[dB], as the line of sight component is stronger the better performance is obtained.

• International journal of advanced smart convergence
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• v.4 no.1
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• pp.64-70
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• 2015

This paper proposes fluorescent electronic ballast with high power factor and low line input current harmonics. The system performance can be improved by a charged pump circuit. Details of design and circuit operation are described. The proposed electronic ballast is modified from single-stage half bridge class D electronic ballast by adding capacitor parallel with each power switch and setting the circuit parameter to operate under class DE inverter condition. By using this proposed method the DC bus voltage can be reduced around by 50% compare with conventional class D inverter circuit. Because the power switches are operated at zero voltage switching condition and low dv/dt of class DE switching. The experimental results show that the proper frequency of the prototype is around 50 kHz with input power factor of 0.982, $THD_i$ 10.2% at full load and efficiency of more than 90%.

• Journal of the Korea Safety Management & Science
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• v.15 no.4
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• pp.357-363
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• 2013

The purpose of this study was to identity the relationships of sub factor among the brain dominance thinking types(A,B,C,D quadrant thinking type) is based on the Whole Brain Modal and self-leadership by Manz. The subjects were 102 undergraduates students from the Hoseo university in Cheonan. The results of this study as follows ; first, the brain dominance thinking type A was the highest and type C was highly rated. Second, the brain dominance thinking type A was not correlated type C and type D. Third, the brain dominance thinking type C and self-leadership sub factor was significantly positively correlated.

• Journal of Radiation Protection and Research
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• v.16 no.1
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• pp.25-32
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• 1991

MCNP code was used to calculate conversion factor H(d)ma at the depths of 0.07 and 10mm within a water phantom recommended by IAEA and within a PMMA phantom required by the US dosimeter proficiency testing programmes. The calculations were performed for an expanded parrallel beam of monoenergetic photons of perpendicular incidence on one faces of the phantom. The results can be used as conversion factor in calibrating individual dosemeters in terms of the dose equivalent quantities defined directly in the phantom.

• Journal of the Korean Society for Precision Engineering
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• v.18 no.7
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• pp.134-142
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• 2001

The integrals $J_k$(k=1,2) in the rectilinear anisotropis body in 2-D were determined using Lekhnitskii formalism. The relationship between $J_k$ and stress intensity factors are implified by the important equation between elastic compliance. The numerical evaluation of stress intensity factor for the single edge crack in mixed mode is determined by superposing known exact solutions.