• Bulletin of the Korean Chemical Society
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• v.29 no.1
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• pp.111-116
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• 2008

A piperazinylalkylisoxazole library containing 86 compounds was constructed and evaluated for the binding affinities to dopamine (D3) and serotonin (5-HT2A/2C) receptor to develop antipsychotics. Dopamine antagonists (DA) showing selectivity for D3 receptor over the D2 receptor, serotonin antagonists (SA), and serotonin-dopamine dual antagonists (SDA) were identified based on their binding affinity and selectivity. The analogues were divided into three groups of 7 DAs (D3), 33 SAs (5-HT2A/2C), and 46 SDAs (D3 and 5-HT2A/2C). A classification model was generated for identifying structural characteristics of those antagonists with different affinity profiles. On the basis of the results from our previous study, we conducted the generation of the decision trees by the recursive-partitioning (RP) method using Cerius2 2D descriptors, and identified and interpreted the descriptors that discriminate in-house antipsychotic compounds.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.41 no.10
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• pp.97-102
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• 2004

In this paper, a new predistorter controlling modified individual order jntermodulation distortion signals is proposed. The proposed predistorter generates and controls predistorted third and high order IM signals independently. Using predistorted signals, jntermodulation distortion signals of power amplifier are suppressed effectively. The predistortion linearizer has been implemented to operate in Korean PCS basestation transmitting band (1840～1870MHz). The test results show that IMD3 and IMD5 (C/I) of power amplifier are improved more than 40dB and 23dB for CW two tone signals, respectively. The predistorter improves the adjacent channel power ratio (ACPR) more than 10dB at 885KHz offset point for CDMA (IS-95) signals.

• 한국정보디스플레이학회:학술대회논문집
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• 2002.08a
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• pp.498-499
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• 2002

In In order to develop liquid crystal mixtures of high response time and high nematic-isotropic transition temperature ($T_{NI}$) for LCD-TV application, novel liquid crystal molecules with a fluoro-isothiocyanate moiety were synthesized. They showed remarkably high $T_{NI}$ over 200 $^{\circ}C$, wide mesophase range of 170 $^{\circ}C$, high dielectric anisotropy of 14 and high optical anisotropy of 0.19. New LC Mixtures of the high $T_{NI}$ ($85{\sim}100 ^{\circ}C$) and fast response time ($8{\sim}10ms$) were blended with the novel fluoro-isothiocyanate containing LC molecules, phenylcyclohexanes, bicyclohexanes and ester compounds. It was also studied on optimum pitch of liquid crystal for high speed twisted nematic LCD-TV applicaton. The LC mixtures show a fast speed of the below one frame rate in real 17" TV panel.

• 한국정보디스플레이학회:학술대회논문집
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• 2002.08a
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• pp.413-414
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• 2002

In In order to develop liquid crystal mixtures of high response time and high nematic-isotropic transition temperature ($T_{NI}$) for LCD-TV application, novel liquid crystal molecules with a fluoroisothiocyanate moiety were synthesized. They showed remarkably high $T_{NI}$ over 200 $^{\circ}C$, wide mesophase range of 170 $^{\circ}C$, high dielectric anisotropy of 14 and high optical anisotropy of 0.19. New LC Mixtures of the high $T_{NI}$ (85${\sim}$100 $^{\circ}C$) and fast response time (8${\sim}$10ms) were blended with the novel fluoroisothiocyanate containing LC molecules, phenylcyclohexanes, bicyclohexanes and ester compounds. It was also studied on optimum pitch of liquid crystal for high speed twisted nematic LCD-TV applicaton. The LC mixtures show a fast speed of the below one frame rate in real 17" TV panel.

• Proceedings of the KAIS Fall Conference
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• 2011.05a
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• pp.500-503
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• 2011

본 논문에서는 RTO 반응기의 최적 조업 조건을 도출하고자 현재 조업 중인 RTO 반응기 촉매층의 압력분포, 유속분포, 유선장, 체류시간, 온도분포 등에 대하여 분석하였고 최적의 조업 조건을 도출하기 위한 전상유체해석을 수행하였다. 전산 해석 결과, 현재 조업중인 반응기 촉매층의 축열재로 인한 압력손실은 크지 않은 것으로 나타났으며, 세라믹 필터 이후 유속은2-3 m/s로 특별한 편류없이 비교적 안정적 유속분포룰 보이고 있었다. 그러나 기류분포를 좀 더 개선하려고 한다면 설비 내부에 플래넘과 촉매층 접속 구간 연장 등의 방법을 고려할 수 있을 것으로 판단된다. 그러나 기류안내판이나 다공판 부착 등의 방법은 큰 효과는 없을 것으로 나타났다.

• Proceedings of the Ginseng society Conference
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• 1998.06a
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• pp.115-126
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• 1998

Four new dammarnae-glycosides named ginsenosides Rgs, Rh4, RsB and Rf2 have been isolated 1'rom Korean red ginseng, the root of Panax ginseng C. A. Meyer (Araliaceae) and their chemical structures have been elucidated by chemical and spectroscopic methods, including'H-'H COSY, HMQC, HMBC, NOESY, as 3-0- [$\beta$-D-glucopyranosyl(1 ~2)-$\beta$-D-glucopyranosyl] dammar-20(22) , B4-diene-3P,12P-diol (ginsenoside Rgs),6-0-$\beta$-D-glucopyranosyl-dammar-20(22),24-diene-3P,6P, 12P-triol (ginsenoside Rh4),3-0- [6" -0-acetyl-D-glucopyranosyl(1 ~2)--D-glucopyranosyl] 20(5)- protopanaxadiol (ginsenoside Rs3) and 6-0- [u-L-rhamno-pyranosyl(1 ~2)-$\beta$-D-glucopyranosyl] dammarane -3$\beta$, 6a, 12 $\beta$, 20(R),25-pentol(ginsenoslde Rfa). The absolute stereo structure of a double bond at C-20(22) was determined as entgegen type by applying NOESY.OESY.

• Korean Journal of Plant Resources
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• v.20 no.3
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• pp.226-233
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• 2007

To develop a clinically available saponin- or sapogenin complex from Oriental medicines, the EtOH extract (KPRG-A) was obtained by extracting from the four crude drugs, Kalopanacis Cortex, Platycodi Radix, Rubi Fructus and Glycyrrhizae Radis. The BuOH fraction (KPRG-B), a crude saponin complex, was prepared by fractionating KPRG-A, which were further completely hydrolyzed to afford the sapogenin complex (KPRG-D). In an attempt to find the antinoicpetive effects of the saponin complex and sapogenin complex, KPRG-C, and -D, were assayed by writhing-, hot plate-, and tail-flick tests using mice or rats. The three samples were also subjected to antiiflammatory tests using serotonin-induced and carrageenan-induced hind paw edema mice and rats, respectively. The three samples significantly reduced inflammations and pains of the experimental animal. The potency were found in the order of KPRG-D> KPRG-C> KPRG-B. The most active sample, KPRG-D, caused no death, no body increase or no anatomical pathlogic change even at 2,000 mg/kg dose. These results suggest that a sapogenin complex, KPRG-D, which was found to contain mainly hederagenin, platycodigenin, polygalacic acid, 23-hydroxytormentic acid, glycyrrhetic acid together with minor triterpene acids, could be a potential candidate for antiinflammatory therapeutics.

• Journal of the Korean Chemical Society
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• v.10 no.4
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• pp.149-152
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• 1966

An insecticide was obtained by condensation of chloral hydrate with p-chloroanisole. The structure of the insecticide was found to be 2,2-bis(2-methoxy-5-chlorophenyl)1,1,1-trichloroethane(M.C.T.). The best conditions for this condensation reaction were as follows: 1) The sulfuric acid concentration: 93% 2) The mole ratio of sulfuric acid to p-chloroanisole: 8 3) The mole ratio of chloral hydrate to p-chloroanisole: 0.7 4) The reaction time and reaction temperature: 12 hrs and 25-30$^{\circ}C$ The insecticidal effects of M.C.T against the Citrus Red Mite and Chrysanthemum Aphid were five times as strong as D.D.T.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.16 no.7
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• pp.593-598
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• 2003

In this paper, 3rd overtone mode energy-trapped filter using modified PbTiO$_3$ system ceramics was manufactured to apply for intermediate frequency(IF) SMD type fillet with splitted electrode and gap size. To investigate the effects of splitted electrode and gap size on filter characteristics of 3rd overtone mode energy-trapped filter, ceramic wafers were fabricated by etching splitted rectangular electrode size(b$\times$d) of b=0.4, 0.6, 0.8, 1mm, d=0.3, 0.4, 0.5, 0.6mm and gap size(c) c=0.2, 0.3, 0.4, 0.6mm, respectively. And then, SMD type ceramic filter were fabricated with the size of 3.7$\times$3.1$\textrm{mm}^2$. SMD type ceramic filter with the size of b=0.8mm, d=0.4mm and gap(c)=0.4mm, which showed insertion loss of 2.951dB, 3dB bandwidth of 54.7kHz and 20dB stop bandwidth of 129.27kHz, was suitable for IF bandpass filter application.

• Proceedings of the Korea Information Processing Society Conference
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• 2001.04a
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• pp.453-456
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• 2001

21세기에 새로운 분야로 대두되고 있는 가상현실은 많은 사람들의 흥미를 끌고 있다. 상상 속에서나 가능하던 일들을 현실감과 입체감을 통해 실제처럼 느낄 수 있게 해준다는 것이 가상현실의 가장 큰 매력일 것이다. 가상현실을 요하는 멀티미디어 기기들의 활발한 시장진출로 3D 효과를 가진 오디오/비디오의 하드웨어 구현이 불가피하다. 본 연구에서는 휴대용 기기들에서 실시간 3D 입체음향 효과를 얻을 수 있도록 하드웨어를 구성하였다. 기존의 입체음향 기술에서 사용되는 콘볼루션 방법은 계산량이 많기 때문에 실시간 구현이 어렵다. 그러나 제안된 방식은 FFT를 사용하여 주파수 영역에서 처리함으로써 계산량을 줄여 하나의 프로세서로도 실시간 처리가 가능하도록 하였다. 저가/저전력/소형화조건을 요구하는 휴대용 기기에서 3D 입체 음향 효과를 얻을 수 있는 것이다. DSP는 TI(Texas Instruments)사의 16비트 고정소수점(fixed-point) 프로세서인 TMS320C5416을 사용한다. 구현된 3D 입체음향 칩은 입체음향을 필요로 하는 휴대용 MP3 Player, 가전용 오디오/비디오 등에 응용될 수 있다.