• Microbiology and Biotechnology Letters
• /
• v.24 no.3
• /
• pp.380-383
• /
• 1996

Adenosine deaminase inhibitor was extracted from culture broth of Streptomyces sp. strain V-8 with ethylacetate. The ethylacetate extract showed the characteristic UV absorption spectrum of actinomycins at 440-450 nm. The ethylacetate extract was compared with respect to inhibitory behavior against adenosine deaminase from calf intestinal mucosa with actinomycin D, -C complex and actinomycin V. The Ki values for actnomycin D, -C complex, and actinomycin V against adenosine deaminase were determined to be 9.9 $\times$ 10$^{-6}$ M, 9.6 $\times$ 10$^{-6}$ M and 9.3 $\times$ 10$^{-6}$ M, respectively. The Ki value for the ethylacetate extract of culture broth against adenosine deaminase was determined to be 5.7 $\times$ 10$^{-6}$ M. The kinetic parameters of actinomycin D, -C complex, -V and ethylacetate extract of culture broth for adenosine deaminase were as follows:I$_{50}$ = 1.5 $\times$ 10$^{-5}$ M (actinomycin D), 2.7 $\times$ 10$^{-5}$ M (actinomycin C complex), 3.5 $\times$ 10$^{-5}$ M (actinomycin V), 8.9 $\times$ 10$^{-6}$ M (ethylacetate extract of culture broth). The adenosine deaminase was inhibited noncompetitively by ethylacetate extract of culture broth as well as by actinomycin D, -C complex and actinomycin V.

• Korean Journal of Pharmacognosy
• /
• v.12 no.1
• /
• pp.12-14
• /
• 1981

${\beta}-Sitosteryl-3-O-{\beta}-D-glucopyranoside$ was isolated from the seeds of Plantago asiatica (Plantaginaceae). The assignments of $^{13}C$ NMR spectra of ${\beta}-sitosterol$ and ${\beta}-sitosteryl-3-O-{\beta}-D-glucopyranoside$ were made by comparing with $^{13}C$ NMR spectra of cholesterol and $cholesteryl-3-O-{\beta}-D-glucopyranoside$. Our data indicate that the revision of previous $^{13}C$ NMR spectral assignment is needed.

• 한국정보통신설비학회:학술대회논문집
• /
• 2004.08a
• /
• pp.109-112
• /
• 2004

오늘날 급속한 컴퓨팅 환경의 변화에 따라 방송, 통신, 기계 등 디지털 컨버전스 패러다임으로 데스크탑 컴퓨터에 제한적이던 정보 서비스가 언제, 어느곳에서든 가능한 유비쿼터스 시대가 도래하고 있다. 가정에서도 또한, 유비쿼터스 홈 환경이 조성 되면서 댁내 보안, 건강 모니터링 및 진료, 오락, 교육, 전자상거래 등 다양한 서비스가 이루어질 것이다. 이러한 환경에 적절한 멀티미디어 컨텐츠의 안전하고 체계적인 관리 및 보호가 필요할 것이다. 본 논문에서는 이러한 유비쿼터스 환경에서의 멀티미디어서비스를 사용자의 상황인지 정보를 통해 지능화된 미디어 서비스 및 멀티미디어 컨텐츠의 체계적이고 안전한 관리 및 보호를 위한 시스템을 제안한다.

• Korean Journal of Materials Research
• /
• v.17 no.9
• /
• pp.500-506
• /
• 2007

The effects of anisotropic surface energy on the microstructure development of porous materials have been studied through Monte Carlo simulation using a three dimensional lattice. The changes in porosity ($f_v$), mean grain diameter ($D_s$), fraction of connected pores ($f_{v,c}$) and contiguity of the solid phase (C) were examined in cases with three different ${\gamma}_{SV}$ relations and initial grain diameters ($D_{s,o}$). It has been found that larger ${\gamma}_{SV}$ enhances sintering of particles and increases C and does not change $D_s$. And Introducing anisotropic ${\gamma}_{SV}$ brought an increase in $f_v$ and $f_{v,c}$ and an decrease in $D_s$ and C, and this tendency become more marked for fine $D_{s,o}$.

• Proceedings of the KIEE Conference
• /
• 2002.07c
• /
• pp.1652-1654
• /
• 2002

The defects making partial discharge(PD) in a C-GIS(Cubicle Insulated Switchgear) initiate acoustic wave which can be detected using acoustic emission sensor placed outside or inside the C-GIS enclosure. In this paper, partial discharge property for 2 locations for AE sensor and 3 locations for defects in C-GIS are presented and PD waveforms were analyzed by PRPDA(Partial Resolved Partial Discharge Analysis). As a result, using post amplifier having gain of 10,000 and band pass filter having $20kHz{\sim}300kHz$, resolution of waveforms AE sensor signal by detected was good. Noise level was about 80 mV.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.14 no.6
• /
• pp.2735-2742
• /
• 2013

The purpose of this study is to assess the association of vitamin D and pulse pressure in Korean adults. The data for analysis were obtained from Korea National Health and Nutrition Examination Survey 2010. PP showed a significant positive correlation with Age(p<0.01), TG(p<0.01), TC(p<0.01), FBS (p<0.01), BMI(p<0.01) and Waist measurement(p<0.01). PP showed a significant negative correlation with HDL-C(p<0.01), Height(p<0.01), Weight(p<0.01) and 25(OH)D(p<0.01). When a multiple linear regression analysis was performed, PP was considered as the dependent variable, Age, Height, Weight, Waist measurement, BMI, TC, TG, HDL-C, FBS and 25(OH)D as independent parameters, PP maintained a significant association only with Age(p<0.001), Waist measurement(p<0.001), FBS(p<0.001), 25(OH)D(p<0.001), TC(p<0.001), Weight(p<0.001), HDL-C(p<0.001). In conclusion, Our results suggest that vitamin D decrease may contribute to higher PP. To maintain standard level of vitamin D may be expected that decrease in incidence of coronary arterial disease.

• Proceedings of the IEEK Conference
• /
• 2001.06b
• /
• pp.229-232
• /
• 2001

4H-SIC(silicon carbide) MESFET large signal model was studied using modified Materka-Kacprzak large signal MESFET model. 4H-SiC MESFET device simulation have been conducted by Silvaco's 2D device simulator, ATLAS. The result is modeled using modified Materka large signal model. simulation and modeling results are -8V pinch off voltage, under $V_{GS=0V}$, $V_{DS=25V}$ conditions, $I_{DSS=270㎃}$mm, $G_{m=45㎳}$mm were obtained. Through the power simulation 2GHz, at the bias of $V_{GS=-4V}$ and $V_{DS=25V}$, 10dB Gain, 34dBm(1dB compression point)output power, 7.6W/mm power density, 37% PAE(power added efficiency) were obtained.d.d.d.

• Bulletin of the Korean Chemical Society
• /
• v.35 no.8
• /
• pp.2299-2303
• /
• 2014

Two diastereoisomers of cyclo(Pro-Tyr) have been synthesized simultaneously. The crystal structures and conformations of both cyclo($\small{L}$-Pro-$\small{L}$-Tyr) and a racemic mixture of cyclo($\small{D}$-Pro-$\small{L}$-Tyr) and cyclo($\small{L}$-Pro-$\small{D}$-Tyr), abbreviated as rac-cyclo($\small{D}$-Pro-$\small{L}$-Tyr/$\small{L}$-Pro-$\small{D}$-Tyr), have been determined by a single-crystal X-ray diffraction study at low temperature. The crystals of rac-cyclo($\small{D}$-Pro-$\small{L}$-Tyr/$\small{L}$-Pro-$\small{D}$-Tyr) belong to orthorhombic space group $Pna2_1$ with a = 10.755 (1), b = 12.699 (1), c = 9.600 (1) ${\AA}$ and Z = 4. The tyrosine side chain is folded towards the diketopiperazine (DKP) ring. The DKP ring adopts a twist boat conformation with pseudo symmetry $C_{2v}$. The pyrrolidine ring has an envelope conformation with the N5, C4, C7 and C8 atoms in a plane. The crystal of rac-cyclo($\small{D}$-Pro-$\small{L}$-Tyr/$\small{L}$-Pro-$\small{D}$-Tyr) is stabilized by hydrogen bonds between amide N2-H2 and carbonyl oxygen O2 in the neighbor. The hydroxyl group of tyrosine residue is also hydrogen bonded to the oxygen of the carbonyl group of the DKP ring in the next molecule. The spectroscopic properties of both isomers are also described.

• Korean Journal of Fisheries and Aquatic Sciences
• /
• v.48 no.6
• /
• pp.913-919
• /
• 2015

In vertebrates, the vitamin D receptor (VDR), a member of the nuclear receptor superfamily, binds the biologically active ligand $1{\alpha},25-(OH)_2$-vitamin $D_3$ (1,25 $D_3$). Nearly all vertebrates, including Agnatha, possess a VDR with high ligand selectivity for 1,25 $D_3$ and related metabolites. Although a putative ancestral VDR gene is present in the genome of the chordate invertebrate Ciona intestinalis, the functional characteristics of marine invertebrate VDR are still obscure. To elucidate the ascidian Halocynthia roretzi VDR (HrVDR), we cloned full-length HrVDR cDNA and investigated the transcriptional activity of HrVDR in HEK293 cells. HrVDR consists of 1,680 nucleotides (559 amino acids [aa]), including a short N-terminal region (A/B domain; 26 aa), DNA-binding domain (C domain; 72 aa), hinge region (D domain; 272 aa), and C-terminal ligand-binding domain (E domain; 161 aa). The amino acid sequence identity of HrVDR was greatest to that of C. intestinalis VDR (56%). In the luciferase reporter assays, the transcriptional activity of HrVDR was not significantly increased by 1,25 $D_3$, whereas the farnesoid X receptor agonist GW4064 increased the transactivation of HrVDR. These results suggest the presence of a novel ligand for and a distinct ligand-binding domain in ascidian VDR.

• Journal of Korea Multimedia Society
• /
• v.20 no.2
• /
• pp.352-362
• /
• 2017

This paper proposes an algorithm for automatically converting and displaying rainfall radar data on a 3D GIS platform. The weather information displayed like rainfall radar data is updated frequently and large-scale. Thus, in order to efficiently display the data, an algorithm to convert and output the data automatically, rather than manually, is required. In addition, since rainfall data is extracted from the space, the use of the display image fused with the 3D GIS data representing the space enhances the visibility of the user. To meet these requirements, this study developed the Auto Data Converter application that analyzes the raw data of the rainfall radar and convert them into a universal format. In addition, Unity 3D, which has good development accessibility, was used for dynamic 3D implementation of the converted rainfall radar data. The software applications developed in this study could automatically convert a large volume of rainfall data into a universal format in a short time and perform 3D modeling effectively according to the data conversion on the 3D platform. Furthermore, the rainfall radar data could be merged with other GIS data for effective visualization.