• 한국식품과학회지
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• 제19권1호
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• pp.38-41
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• 1987

팽창된 복숭아 통조림으로부터 분리된 Saccharomyces cerevisiae Py9와 Saccharomyces chevalieri Pw7의 자낭포자의 열저항성을 측정하였다. 그 결과 S. cerevisiae Py9는 $D_{58}$=6.5분, $D_{60}$=2.5분, $D_{62}$=1.25분이었고 Z값은$5.5^{\circ}C$로 나타났다. 그리고 S. chevalieri Pw7은 $D_{58}$=35분, $D_{60}$=3.5분, $D_{62}$=1.5분이었고 Z값은 $3.4^{\circ}C$로 나타났다. 열처리를 했을때 미생물 사멸이 직선인 부분과 그렇지 않은 부분으로 나뉘어지므로 즉, tailing 현상으로 인해 가열치사속도곡선과 가열치사시간곡선에 나타난 대로의 열처리 만으로는 효모의 완전 살균이 불가능함을 알 수 있었다.

• Molecules and Cells
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• 제26권5호
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• pp.481-485
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• 2008

As an inhibitor of phosphatidylcholine-specific phospholipase C (PC-PLC), D609 has been widely used to explain the role of PC-PLC in various signal transduction pathways. This study shows that D609 inhibits group IV cytosolic phospholipase $A_2$ ($cPLA_2$), but neither secretory $PLA_2$ nor a $Ca^{2+}$-dependent $PLA_2$. Dixon plot analysis shows a mixed pattern of noncompetitive and uncompetitive inhibition with $K_i=86.25{\mu}M$ for the $cPLA_2$ purified from bovine spleen. D609 also time- and dose-dependently reduces the release of arachidonic acid from a $Ca^{2+}$- ionophore A23187-stimulated MDCK cells. In the AA release experiment, $IC_{50}$ of D609 was ${\sim375}{\mu}M$, suggesting that this reagent may not enter the cells easily. The present study indicates that the inhibitory effects of D609 on various cellular responses may be partially attributable to the inhibition of $cPLA_2$.

• Mycobiology
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• 제28권4호
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• pp.185-189
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• 2000

The antifungal activity of methanolic extracts of Centella asiatica and Andrographis paniculata leaves was observed against fourteen fungi, viz., Alternaria alternata, A. brassicae, A. brassicicola, A. solani, A. tenuissima, Cercospora blumae, Curvularia lunata, C. penniseti, and Drechslera monoceras, D. oryzae, D. turitica, Fusarium albizziae and F. udum. Different concentrations of the methanolic extract (1000, 2000, 3000, 5000, 7000, 10000ppm) were used. The effect of mixed leaf extract (1500 ppm of C. asiatica + 1500 ppm of A. paniculata) and its 1:2 ad 1:4 dilutions were also studied. The individual extracts of both the plants showed significant inhibitory effect on spore germination of all the fungi tested. F. udum, F. albizzae, D. oryzae, D. turtica, and D. monoceras were particularly sensitive to these extracts. In general, the extract of C. asiatica showed a higher inhibitory effect in all concentrations against all the fungi as compared to A. paniculata, except for A. brassicae A. solani, D. oryzae, D. penniseti and Curvularia sp. The inhibitory effect of extracts increased when they were used in combination with or without dilutions against A. brassicicola, A. solani A. brassicae, A. alternata, A. tenussima, C. blumae, C. lunata, C. penniseti and Curvularia species. Higher efficacy of active ingredient of these extracts under field condition is envisaged against plant pathogens.

• 대한원격탐사학회:학술대회논문집
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• 대한원격탐사학회 2003년도 Proceedings of ACRS 2003 ISRS
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• pp.1255-1257
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• 2003

This study proposes a single-channel satellite remote sensing algorithm for retrieving aerosol optical thickness over global ocean using FY-1C/1D data. An efficient lookup table (LUT)method is adopted in this algorithm to generate apparent reflectance in channel 1 and channel 2 of FY-1C/1D over ocean. The algorithm scale the apparent reflectance in cloud-free conditions to aerosol optical thickness using a state-of-art radiative transfer model 6S with input of the relative spectral response of channel 1 and 2 of FY-1C/1D. Monthly mean composite maps of the aerosol optical thickness have been obtained from FY-1C/1D global area coverage data between 2001 and 2003. Aerosol optical thickness maps can show the major aerosol source which are located off the west coast of northern and southern Africa, Arabian Sea and India Ocean. These result is very similar to other satellite sensors such as AVHRR and MODIS in the location area of heavy aerosol optical thickness over global ocean. The algorithm have been used to FY-1D operational performance and it is the first operational aerosol remote sensing product in China.

• Journal of Gastric Cancer
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• 제6권3호
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• pp.132-138
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• 2006

목적: 도파민은 중추신경전달물질이지만 위장관에서 도파민수용체와 결합하여 점막상피세포 증식, 상피세포의 보호, 위암 세포증식과 관련이 있는 것으로 알려져 있다. 본 연구에서는 위암에서 기원한 세포주를 이용하여 도파민과 각각의 도파민 수용체가 위암 세포 증식과 억제에 작용하는 역할에 대해 알아보았다. 대상 및 방법: 위암세포기원에서 각각 유래한 세포주인 SNU601과 KCU-C2를 이용하여 RNA 추출 후 RT-PCR 시행 후 도파민수용체 D1, D2L과 D2S 각각에 대한 primer로 PCR을 시행하여 수용체 유전자의 상대적인 발현정도를 측정하였다. 도파민과 Dl 수용체의 대항제인 SCH 23390과 D2 수용체 대항제인 raclopride를 사용하여 약물처리에 따른 위암세포주에서 세포 증식에 대한 분석을 하였다. 결과: KCU-C2 세포주에서 D1과 D2L과 D2S 유전자 mRNA의 상대적인 발현정도는 모두 높은 발현을 보였지만, SNU 601 세포주에는 mRNA의 발현이 모두 낮은 수준이었으며, 특히 D2L mRNA는 발현되고 있지 않았다. 약물처리에 따른 위암세포주에서 세포증식에 대한 분석에서는 D1과 D2S 수용체를 통한 도파민의 신호는 세포의 증식을 억제하였고 D2L 수용체를 통한 도파민의 신호는 세포의 증식을 유도하였다. 결론: 본 연구를 통해 도파민이 위암의 세포증식과 억제에 관여하며, 도파민의 이러한 효과는 도파민의 신호가 어느 수용체를 통해 전달되었느냐에 따라 위암세포의 증식과 억제가 이루어짐을 알 수 있었다.

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 2005년도 춘계학술발표회
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• pp.255-256
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• 2005

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 2005년도 추계학술발표회
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• pp.197-198
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• 2005

• 대한화학회지
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• 제21권2호
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• pp.75-82
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• 1977

순수한 액체의 증가압에 미치는 동위원소 효과를 연구하였고, 증기압 비를 계산하였다. Significant Structure Theory of Liquid를 사용한 계산결과에 의하면, $C_2H_4/C_2H_2D_2$(trans)계 에서는 분자량과 관성능률에 의한 효과가 현저하고, $C_2H_2D_2(trans)/C_2H_2D_2(cis)$계에서는 분자 회전이 자유롭지 못한 데서 오는 영점에너지 효과가 현저했다. 그리고, $CH_3OH/CH_3OD$계에서는 분자간 인력이 동위원소에 따라 다르기 때문임이 밝혀졌다. $CH_4/CD_4,\;SiH_4/SiD_4,\;GeH_4/GeD_4$ 동위원소계에서는 분자량에 의한 효과가 $CH_4/CD_4 >SiH_4/SiD_4 >GeH_4/GeD_4$의 순서로 감소함을 알 수 있었다.

• 미생물학회지
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• 제9권2호
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• pp.55-60
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• 1971

Among 50 yeasts of red pepper paste isolated and identified in the previous report, 12 strains of yeast which possess osmophilic and non-film characteristics were examined their growth rates and alcohol fermentation ability in red pepper medium. 5 strains of yeast possessing powerful growth rates and excellent alcohol fermentation ability were selected as excellent yeasts in this experiment. And their cultural conditions, salt resistance and red pepper concentration upon the growth were examined in this report. The results obtained were as follows ; 1) Among 12 strains of yeast, Saccharomyces cerevisiae group II(strain $D_1$), Saccharomyces oviformis($D_2$), Saccharomyces steineri($M_3$), Saccharomyces rouxii($D_9$) and Saccharomyces mellis($G_8$) were selected as excellent yeasts. 2) Among 5 strains of yeast selected, the strain $D_1$ and $D_2$showed the best alcohol fermentation ability and the best fermentative flavour. 3) The optimum temperature for growth of the strain $D_1$ and $D_2$ was $25^{\circ}C$$M_3$, $D_9$ and $G_8$ $30^{\circ}C$$D_1$ and $D_2$ was $62^{\circ}C$$M_3$,$D_9$ and $G_8$ ws 60.deg.C with treatment for 10 minutes. 4) The optimum pH for growth of all strains was around 5.0. 5) The strain $D_1$ and $M_3$were grown exceedingly well on the emdia containing 3 percent of NaCl and $D_2$,$D_9$ and $G_8$ on the media containing 6 percent of NaCl. 6) In the case of 5 percent of red pepper liquor added 5 percent of glucose was more nutritional than in the case of 5 percent glucose only. However, the growth rates of yeasts were restrained by the increase of red pepper concentration.

• 생약학회지
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• 제25권3호
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• pp.199-203
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• 1994

Chemical examination of the leaves of Betula platyphylla var. latifolia has led to the isolation and characterization of five flavonoid glycosides including two C-glucosyl flavonoids. The structures of these compounds were elucidated as myricetin $3-O-{\alpha}-_L-rhamnoside$ (myricitrin), $quercetin-3-O-{\beta}-_D-glucopyranoside$ (isoquercitrin), $quercetin-3-O-{\beta}-_D-glucopyranoside$ (hyperoside), $nalingenin-6-C-{\beta}-_D-glucopyranoside$ (hemiphloin) and $aromadendrin-6-C-{\beta}-_D-glucopyranosidre(6-C-glucosyldihydrokaempferol)$ on the basis of physico-chemical and spectroscopic evidences.