• Title/Summary/Keyword: D 002

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Screening method for amines by derivatization reaction on TLC (TLC 상 유도체화 반응을 이용한 아민 계 화합물의 Screening 방법)

  • Choi, Sung-Woon;Lee, Hye-In;Sung, Nack-Do
    • Analytical Science and Technology
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    • v.26 no.4
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    • pp.228-234
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    • 2013
  • Methamphetamine is an amine-containing illegal drug and is distributed unlawfully in South Korea. Finding a rapid, convenient and semi-quantitative determination method for methamphetamine is a very important issue in the area of forensic drug testing. As an effort to develop new screening method, the reactions between three organic compounds which are structurally similar to methamphetamine and N-(9-fluorenylmethoxycarbonyloxy) succinimide (FMOC-NHS) were performed on silica gel ($SiO_2$) TLC plates. Three reference compounds were synthesized and used for the identification, comparison and study of the limit of detection (LOD) of the products obtained from a direct reaction on a TLC plate. As a result, FMOC-NHS as a derivatization reagent generated compounds containing highly UV-active functional groups on the TLC plate after reacting with primary- and secondary amines. In the experiment 2D the LOD of amines was in the range of 0.045 and 0.01 mg/mL ($2{\mu}L/spot$), and in 1D the LOD was in the range of 0.002 and 0.007 mg/mL ($2{\mu}L/spot$). The LODs of the compounds tested were dependent on the concentration of the derivatizing reagent.

Crystal growth and photocurrent of $Mg_{x}Zn_{1-x}$Te single crystals ($Mg_{x}Zn_{1-x}$Te 단결정 성장과 광전류 특성)

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    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.11 no.1
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    • pp.6-13
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    • 2001
  • By using a vertical Bridgeman method, single crystalline structures of $Mg_xZn_{1-x}Te(0{\le}X{\le}0.48)$ were grown for various Mg mole compositions. With the increasing Mg fraction, the lattice constant is linearly increased from 6.103 to 6.239$\AA$ for the range of $0{\le}X{\le}0.48$ and the lattice constant of zincblende MgTe was linearly extrapolated to the value of 6.433$\pm$0.002$\AA$. The optical properties of the crystalline structure were characterized with photocurrent measurements. As a results of photocurrent spectra, the single crystalline $Mg_xZn_{1-x}Te$ show the energy bandgap of 2.380 and 2.260eV at 4.2 and 294 K, respectively. The photocurrent peak blueshifts with increasing Mg mole fraction and show the linear dependence of energy bandgap, $E_g$(X)=b+(0.8)X. The extrapolation shows the energy bandgaps of MgTe of 3.18 and 3.06eV at the temperatures of 4.2 and 294K, respectively. Furthermore, the photocurrent peaks redshifts with increasing temperature and the temperature coefficient is given to the value of $dE_g$/dT=-(5.6~$6.1){\times}10^{-4}$eV/K. for the temperature range above 100K.

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Quality characteristics of non steamed oriental melon Makgeolli by adding sucralose (Sucralose 첨가에 따른 참외 생쌀발효 막걸리의 품질특성)

  • Kim, Ok Mi;Jo, Yong Jun;Jeong, Yong Jin
    • Food Science and Preservation
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    • v.22 no.3
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    • pp.377-384
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    • 2015
  • This study examined the physicochemical quality characteristics of the oriental melon Makgeolli variant by addition of sucralose during its non-steamed fermentation process. The results showed a partial increase in initial sugar content in Makgeolli depending on the level of sucralose addition; and this slight increase in sugar content was exhibited in all intervals into which the sucralose was added during fermentation. The pH of Makgeolli did not exhibit significant changes according to the level of added sucralose until the fourth day of the fermentation process; and the total acidity of Makgeolli did not significantly change in accordance with the varied levels of added sucralose. Reducing sugar rapidly decreased in all intervals of the experiment during the first day of fermentation, and it was then increased slightly staring from the second day of the fermentation. Alcohol content in all experimental intervals was proportionally increased in accordance with the amount of added sucralose during the alcoholic fermentation process. The alcohol content was reached to the final alcohol contents of control (A) 11.27%, 0.001% (w/w) (B) 11.43%, 0.002% (w/w) (C) 11.80%, and 0.003% (w/w) (D) 12.23%. The levels of acetaldehyde, 1-propanol, isobutanol, and isoamyl alcohol in Makgeolli were all proportional to the level of the amount of sucralose added in the fermentation process. The organoleptic characteristics of Makgeolli was accorded with the level of the amount of sucralose. In the sensory evaluation, the experimental interval of 0.003% (w/w) (D) showed the highest scores of 3.30, 2.67, 3.17, and 3.20 in color, odor, taste and overall, respectively.

Expression of Toll-like Receptors, Pro-, and Anti-inflammatory Cytokines in Relation to Gut Microbiota in Irritable Bowel Syndrome: The Evidence for Its Micro-organic Basis

  • Shukla, Ratnakar;Ghoshal, Ujjala;Ranjan, Prabhat;Ghoshal, Uday C
    • Journal of Neurogastroenterology and Motility
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    • v.24 no.4
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    • pp.628-642
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    • 2018
  • Background/Aims A Subset of patients with irritable bowel syndrome (IBS) may have mild inflammation due to immune activation. Toll-like receptors (TLRs) and cytokines may cause intestinal inflammation. We studied their expression in relation to gut microbiota. Methods Expression of TLRs and cytokines was assessed in 47 IBS patients (Rome III) and 25 controls using quantitative real-time polymerase chain reaction. Immunohistochemistry was further performed to confirm the expression of TLR-4 and TLR-5. Results Of 47 patients with IBS, 20 had constipation (IBS-C), 20 diarrhea (IBS-D), and 7 unclassified (IBS-U). The mRNA levels of TLR-4 and TLR-5 were up-regulated in IBS patients than controls (P = 0.013 and P < 0.001, respectively). Expression of TLR-4 and TLR-5 at protein level was 4.2-folds and 6.6-folds higher in IBS-D than controls. The mRNA levels of IL-6 (P = 0.003), C-X-C motif chemokine ligand 11 (CXCL-11) (P < 0.001) and C-X-C motif chemokine receptor 3 (CXCR-3) (P < 0.001) were higher among IBS patients than controls. Expression of IL-6 (P = 0.002), CXCL-11 (P < 0.001), and CXCR-3 (P < 0.001) were up-regulated and IL-10 (P = 0.012) was down-regulated in IBS-D patients than controls. Positive correlation was seen between TLR-4 and IL-6 (P = 0.043), CXCR-3, and CXCL-11 (P = 0.047), and IL-6 and CXCR-3 (P = 0.003). Stool frequency per week showed positive correlation with mRNA levels of TLR-4 (P = 0.016) and CXCR-3 (P = 0.005), but inversely correlated with IL-10 (P = 0.002). Copy number of Lactobacillus (P = 0.045) and Bifidobacterium (P = 0.011) showed correlation with IL-10 in IBS-C, while Gram-positive (P = 0.031) and Gram-negative bacteria (P = 0.010) showed correlation with CXCL-11 in IBS-D patients. Conclusions Altered immune activation in response to dysbiotic microbiota may promote intestinal inflammation in a subset of patients with IBS.

Orientation, Surface Roughness and Piezoelectric Characteristics of AlN Thin Films with RF Magnetron Sputtering Conditions (RF 마그네트론 스퍼터링 공정 조건에 따른 AlN 박막의 배향성, 표면 거칠기 및 압전 특성에 관한 연구)

  • Bang Jung-Ho;Chang Dong-Hoon;Kang Seong-Jun;Kim Dong-Guk;Yoon Yung-Sup
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.43 no.4 s.346
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    • pp.1-7
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    • 2006
  • AlN thin films have been fabricated by using RF magnetron sputtering method and their crystal orientations, microstructures and piezoelectric properties have been investigated with variation of the $Ar/N_2$ gas ratio and the substrate temperature. Particularly, when the $Ar/N_2$ gas ratio and the substrate temperature are 10/10 (sccm) and $400^{\circ}C$, respectively, the AlN thin film exhibits the highest (002) orientation. The result of the surface roughness measurement by using AFM shows that the surface roughness becomes better as the partial pressure of $N_2$ increases at the substrate temperature of $400^{\circ}C$ and it becomes the smallest value of 2.1 nm when $Ar/N_2$ is 0/20 (sccm). The AFM measurement also shows that when $Ar/N_2$ is 10/10 (sccm) shows that surface roughness becomes better as the substrate temperature increases from room temperature up to $300^{\circ}C$ and then it becomes worse as the substrate temperature goes up from $300^{\circ}C$. At the substrate temperature of $300^{\circ}C$ and $Ar/N_2$=10/10 (sccm), the surface roughness is 3.036 nm. The piezoelectric constant ($d_{33}$) of AlN thin film is measured by Pneumatic probe method. The measurement shows that the AlN thin film with the highest (002) orientation, fabricated at $Ar/N_2$=10/10 (sccm) and the substrate temperature of $400^{\circ}C$, has the best Piezoelectric constant ($d_{33}$) of 6.01 pC/N.

A Field Survey on Concentration of Odor Compounds in Pig Buildings and Boundary Areas (돈사 내 및 부지경계에서 악취물질 발생 조사 연구)

  • Yoo Yong-Hee;Kim Tae-Il;Jeong Jong-Won;Gwak Jeong-Hun;Choi Hee-Chul;Song Jun-Ik;Yang Chang Bum;Jang Young-Kee;Kim Ho-Jung;Song Ki-Pong
    • Journal of Animal Environmental Science
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    • v.11 no.1
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    • pp.45-54
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    • 2005
  • A field survey was conducted to determine the concentration of odor compounds from pig buildings and that were 20 meters within the boundary area. The odor compounds were measured from large, medium and small farms with enclosed and open housing systems and slurry and sawdust manure fermentation treatment methods. Among the odor compounds investigated, ammonia ($NH_3$) had the highest concentration at 0.9 ${\~}$ 21.0 ppm followed by Hydrogen Sulfide($H_2S$) with a wide variation concentration of 51.9 ${\~}$ 6,712.4 pub, Uethylmercaptan($CH_3SH$) with non-detectable (N. D.) ${\~}$ 12.9 ppb, Dimethylsulphide($(CH_3)_2S$), with N. D. ${\~}$ 5.2 ppb and Dimethyldisulphide($(CH_3)_2S_2$) with N. D. ${\~}$ 2.6 ppb. Considering the prevailing wind direction and air velocity ranging from 0.23 to 0.73 m/s within the boundary area, the odorous matters; $NH_3$, $H_2S$, $CH_3SH$, $(CH_3)_2S_2$ and $(CH_3)_2S$ were 0.2${\~}$4.5 ppm, 0.01 ${\~}$0.06 ppb, N. D. ${\~}$0.009ppb, N. D.${\~}$0.002ppb and N. D. for $(CH_3)_2S$ respectively. These findings suggested that the Odor compounds $(CH_3)_2S_2$ had the lower detection in the boundary area whilst $(CH_3)_2S$ had no detection level within a 20-meter distance only. However, with these results odor compounds from pig buildings has to be further investigated under more controlled environmental factors.

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Practical Data Transmission in Cluster-Based Sensor Networks

  • Kim, Dae-Young;Cho, Jin-Sung;Jeong, Byeong-Soo
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.4 no.3
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    • pp.224-242
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    • 2010
  • Data routing in wireless sensor networks must be energy-efficient because tiny sensor nodes have limited power. A cluster-based hierarchical routing is known to be more efficient than a flat routing because only cluster-heads communicate with a sink node. Existing hierarchical routings, however, assume unrealistically large radio transmission ranges for sensor nodes so they cannot be employed in real environments. In this paper, by considering the practical transmission ranges of the sensor nodes, we propose a clustering and routing method for hierarchical sensor networks: First, we provide the optimal ratio of cluster-heads for the clustering. Second, we propose a d-hop clustering scheme. It expands the range of clusters to d-hops calculated by the ratio of cluster-heads. Third, we present an intra-cluster routing in which sensor nodes reach their cluster-heads within d-hops. Finally, an inter-clustering routing is presented to route data from cluster-heads to a sink node using multiple hops because cluster-heads cannot communicate with a sink node directly. The efficiency of the proposed clustering and routing method is validated through extensive simulations.

Occurrence of longtail tuna (Thunnus tonggol) juvenile in Korean waters (백다랑어 (Thunnus tonggol) 치어의 국내 출현)

  • Yoon, Sang Chul;Choi, Kwang Ho;Jeong, Yeon Kyu;Lee, Dong Woo;Ryu, Jung Hwa
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.49 no.4
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    • pp.500-504
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    • 2013
  • A total of 24 juvenile specimens of Thunnus tonggol (5.45~7.26mm in total length) of the Sombridae were collected from the southeast sea of Jeju Island during 26~30 July, 2013. Twenty-four specimens identified T. tonggol have melanophores distributed on the 1st dorsal-fin rays, the dorsal of head and vetral side. Three individulas were identified using mitochondrial DNA cytochrome oxidase submit 1 (CO1) sequences (452 base pairs). All were identified as T. tonggol, their mtCO1 sequences being consistent with those of Thunnus tonggol (d=0.000), followed by Thunnus albacares (d=0.002) and Thunnus obesus (d=0.007).

Autonomous swimming technology for an AUV operating in the underwater jacket structure environment

  • Li, Ji-Hong;Park, Daegil;Ki, Geonhui
    • International Journal of Naval Architecture and Ocean Engineering
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    • v.11 no.2
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    • pp.679-687
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    • 2019
  • This paper presents the autonomous swimming technology developed for an Autonomous Underwater Vehicle (AUV) operating in the underwater jacket structure environment. To prevent the position divergence of the inertial navigation system constructed for the primary navigation solution for the vehicle, we've developed kinds of marker-recognition based underwater localization methods using both of optical and acoustic cameras. However, these two methods all require the artificial markers to be located near to the cameras mounted on the vehicle. Therefore, in the case of the vehicle far away from the structure where the markers are usually mounted on, we may need alternative position-aiding solution to guarantee the navigation accuracy. For this purpose, we develop a sonar image processing based underwater localization method using a Forward Looking Sonar (FLS) mounted in front of the vehicle. The primary purpose of this FLS is to detect the obstacles in front of the vehicle. According to the detected obstacle(s), we apply an Occupancy Grid Map (OGM) based path planning algorithm to derive an obstacle collision-free reference path. Experimental studies are carried out in the water tank and also in the Pohang Yeongilman port sea environment to demonstrate the effectiveness of the proposed autonomous swimming technology.

Studies on the Distributiion of Vascular Plants in the Islands around the Korean Peninsula (한반도 주변도서의 관속식물 분포에 관한 연구)

  • Paik, Kwang Soo;Yang-Jai Yim
    • The Korean Journal of Ecology
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    • v.5 no.4
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    • pp.143-153
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    • 1982
  • Distributional pattern of vascular plant species in terms of species-area relationship and distances from their species pool on the 53 islands selected in the South Korea were studied. From the relationship between vascular plant species and area the equation of species-area was established as the follow: S=cA2 c=135.52 z=0.226 S; number of species A; area of island In the equation the Z value 0.226 is lower than those of any other localities reported in the world. Z value increased with the increasing distance from the species pool while C value decreased. The relationships of Z and/or C and distance from species pool, D, were established; Z=0.002D+0.176 C=-39.5logD+178.5 The tendency of common species decrease of them with the increasing islands was fifted to the Fisher's logarithm series. Common species 50% above was 39 species, including the most common species, Pinus thunbergii. Quotient of Similarity value by Sorensen (1948) on common species was relatively low i.e. 0.27∼0.47. It is noticeable for their vegetation conditions that the naturalized plant as a indicator of disturbance, for example Erigeron canadensis, was widely distributed.

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