• Tuberculosis and Respiratory Diseases
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• 제46권5호
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• pp.718-722
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• 1999

14세 여자 환자에서 무증상의 전종격동 낭성 종괴가 있어 절제적 생검을 시행하여 고분화성 흉선암종의 광범위한 낭성 변화로 확진되어 제1기의 흉선종을 완전 적출 후 방사선 치료 혹은 병합화학요법 없이 추후 흉부전산화단층촬영 예정으로 외래에서 경과 관찰 중인 1예를 경험하여 문헌 고찰과 함께 보고하는 바이다.

• Tuberculosis and Respiratory Diseases
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• 제62권4호
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• pp.331-335
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• 2007

전종격동 하부에 심장과 연접한 이소성 흉선종은 폐암뿐 아니라 흉선종, 생식세포암, 림프종, 전이성 종양 등의 여러 질환과 감별이 필요하다. 병리조직상으로는 이소성 흉선종에 대한 주의가 없는 경우, 미분화상피암, 암성병변의 림프절 전이, 또는 림프구가 우세하게 관찰되는 경우 림프종 등으로 오진될 수도 있으므로 감별진단에 있어 주의가 필요하다. 또한 낭성 흉선종은 이러한 감별진단을 더욱 어렵게 한다. 저자들은 하부 종격동에 심장 우측과 연접하여 발생한 이소성 낭성 흉선종 환자 1예를 경험하였기에 보고하는 바이다.

• Journal of Chest Surgery
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• 제50권1호
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• pp.68-70
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• 2017

The actual incidence of multiple thymoma is unknown and rarely reported because it remains controversial whether the cases represent a disease of multicentric origin or a disease resulting from intrathymic metastasis. In this case, a patient underwent total thymectomy for multiple thymoma with myasthenia gravis via bilateral video-assisted thoracic surgery. A well-encapsulated multinodular cystic mass, measuring $57mm{\times}50mm{\times}22mm$ in the right lobe of the thymus, and a well-encapsulated mass, measuring $32mm{\times}15mm{\times}14mm$ in the left lobe, were found. Both tumors were type B2 thymoma. Few cases of multiple thymoma with myasthenia gravis have ever been reported in the literature. We report a case of synchronous multiple thymoma associated with myasthenia gravis.

• Journal of Yeungnam Medical Science
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• 제27권2호
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• pp.98-104
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• 2010

원발성 전 종격동 종양은 종격동 종양의 반이상을 차지하고 그 종류도 다양하다. 흉선 상피 종양이 가장 흔하고 악성 흉선종은 드물다. 생식세포종은 두 번째로 흔한 전 종격동 종양으로 보다 어린나이에 발생하며 대부분 양성이다. 임파종은 대부분 전신성 질환의 흉부 침습 형태로 나타나나 원발성 흉부 임파종은 Hodgkin씨 병이 많다. 저자는 대표적인 전종격동 종양의 임상증상과 영상의학적 소견을 소개한다.

• Journal of Chest Surgery
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• 제10권2호
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• pp.355-358
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• 1977

The period from .1959 to 1976, authors experienced 13 cases of thymoma at the Department of Thoracic and Cardiovascular Surgery in National Medical Center. Ten patients were male, and 3 patients were female.Main complaints were cough 76.9%, dyspnea, 69.2%, chest pain 61.6%, myasthenia gravis 23.1 % and S.V.S 23.1%. All of them located anterior mediastinum. 7 cases were benign and 6 cases were malignant. Lymphocytic type was 5 cases, epithelial type 3 case,spindle cell type 1 case, mixed type 2 cases, cystic type 1 case and seminomatous type 1 case. All cases were surgically approached but in malignant cases, only 1 case was palliatively removed and followed radiation therapy. 4 cases were made only biopsy, among them, obstained good response with radiation therapy in seminomatous type case. In benign cases, excellent result was obtained but 2 cases which were combined myasthenia gravis were relapsed the symptoms.

• Journal of Chest Surgery
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• 제25권7호
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• pp.723-726
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• 1992

We have experienced two cases of video thoracosopic excision of mediastinal tumors at the department of thoracic and cardiovascular surgery, Yonsei University, College of medicine. Histologically the mediastinal tumors were cystic thymoma in one & bronchogenic cyst in another. The operative times were rather short and the post-operative courses were not eventful. These patients were discharged with less chest discomforts in post-operative 5 days & have been in good conditions to now.

• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5581-5585
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• 2012

Objective: To explore the relationship between computed tomography (CT) manifestations of thymoma and its WHO pathological classification. Methods: One hundred and five histopathologically confirmed cases were collected for their pathological and CT characteristics and results were statistically compared between different pathological types of thymoma. Results: Tumor size, shape, necrosis or cystic change, capsule integrity, invasion to the adjacent tissue, lymphadenopathy, and the presence of pleural effusion were significantly different between different pathological types of thymomas (P<0.05). Type B2, B3 tumors and thymic carcinomas were greater in size than other types. More than 50% of type B3 tumors and thymic carcinomas had a tumor size greater than 10 cm. The shape of types A, AB, and B1 tumors were mostly round or oval, whereas 75% of type B3 tumors and 85% of thymic carcinomas were irregular in shape. Necrosis or cystic change occurred in 67% of type B3 thymomas and 57% of thymic carcinomas, respectively. The respective figures for capsule destruction were 83% and 100%. Increases in the degree of malignancy were associated with increases in the incidence of surrounding tissue invasion: 33%, 75%, and 81% in type B2, type B3, and thymic carcinomas, respectively. Pleural effusion occurred in 48% of thymic carcinomas, while calcification was observed mostly in type B thymomas. Conclusions: Different pathological types of thymic epithelial tumors have different CT manifestations. Distinctive CT features of thymomas may reflect their pathological types.

• Journal of Yeungnam Medical Science
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• 제6권2호
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• pp.79-90
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• 1989

30례의 종격동 종양의 CT분석 결과, 저자들은 다음과 같이 요약 할 수 있었다. 1. 가장 흔한 종양은 흉선질환 이었으며, 그 다음으로는 기형종, 림프종, 기관지성 낭종, 신경종, 심막낭종의 순이었다. 2. 5례의 흉선종은 균일한 충실성 음영의 종괴로 보였으며, 석회침착, 소엽형성이 각각 1례에서 보였다. 악성흉선종 중 1례에서 피낭형성이 잘된 낭성 종괴로 보였으며, 흉선암종은 주위 경계의 소엽형성을 보인 균일한 음영의 종괴로 보였다. 3. 전 례의 가형종은 모두 낭성종괴로 보였으며, 지방과 석회음영은 각각 2례, 4례에서 보여졌다. 4. 신경종은 4례 모두에서 후종격동에 위치한 균일한 음영의 종괴로 보여졌다. 5. 기관지성 낭종은 기관분기부 하방, 부흉곽지역에 각각 1례, 후기관부에 2례 있었으며, 모두 균일한 음영의 낭성 종괴로 보여졌다. 6 심막낭종은 심장 주위 경계를 따라 난형모양의 낭성 종괴로 보여졌다. 결론적으로 종격동 종괴의 진단에 CT를 실시함으로써 종괴의 정확한 위치, 크기 및 특징적인 구성성분을 관찰할 수 있으며, 이러한 소견으로 종괴의 감별진단에 도움을 얻을 수 있다.

• Journal of Chest Surgery
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• 제26권3호
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• pp.163-169
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• 1993

This is the result of the annual statistic analysis of thoracic and cardiovascular surgical cases in 1992 Korea. Overall 17, 520 cases of surgery [11, 732 cases of thoracic surgery by 54 institutes / 5, 788 cases of cardiovascular surgery by 48 institutes] were done. 1. Tumor [N=2, 532] : Lung was the most frequently involved organ by tumor [54.9%],and the remainders were mediastinum [16.2%] / esophagus [14.8%] / chest wall [11.7%] / tracheobronchus [1.3%] / pleura [1.1%] in order. Of 1, 082 cases of primary lung cancer surgery,the frequency of cell type was squamous [62.6%] / adeno [21.6%] / small cell [7.1%] / large cell [2.7%]. Of 411 cases of mediastinal tumor surgery,the frequency of cell type was neurogenic [28.8%] / thymoma [27.6%] / teratoma [17.7%] / congenital cystic [17.2%]. Of 376 cases of esophageal tumor surgery,primary cancer were the most [85.4%]. 2. Infection [N=3, 157] : Pleura was the most frequently involved organ [59.0%],and the remainders were lung [31.3%] / chest wall [8.6%] / mediastinum [1.1%] in order. 3. Miscellaneous [N=6, 043] : Lung and pleural disease esp. pneumothorax [85.1%] was the most frequent surgical indication. The remainders were chest wall anomaly [3.4%] / benign esophageal disease [3.4%] / diaphragmatic pathology [2.4%] / myasthenia [1.4%] in order. Of 85 cases of thymectomy for myasthenia gravis,thymoma was noted in 58.8%. 1. Congenital heart disease [N=3, 363] : The ratio of noncyanotic to cyanotic heart disease was 3:1. Of 2, 516 cases of noncyanotic heart disease,the frequency of disease entity was VSD [44.1%] / ASD [26.0%] / PDA [19.4%] / PS [3.3%],and that of 847 cases of cyanotic heart disease was TOF [29.4%] / ECD [15.6%] / TGA [9.7%] / DORV [7.6%]. Overall mortalities were 2.1% in noncyanotic and 12.2% in cyanotic heart surgery. 2. Acquired heart disease [N=1, 929] : Of 1, 422 cases of valvular surgery,single mitral pathology was the most frequent candidate [48.0%],and total 1, 574 prosthetic valves which were mainly mechanical [95.6%] were used. Of 376 cases of coronary surgery,triple vessel was the most [35.9%],and the frequency of bypassing grafts was great saphenous vein [52.9%] / internal mammary artery [44.7%] / artificial vessel [2.4%]. Overall mortalities were 3.4% in valvular and 4.5% in coronary surgery. 3. Pericardium,Cardiac tumor,Arrhythmia,Aortic aneurysm,Assist device,and Pacemaker : There were no specific changes compared to previous survey1]. This nation-wide inquiry will be continued and reported annually by KTCS Society.

• Journal of Chest Surgery
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• 제25권12호
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• pp.1383-1390
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• 1992

This is the result of the annual statistic analysis of thoracic and cardiovascular surgical cases in 1991, Korea. 14,715 cases of surgery[thoracic 8,995/cardiovascular 5,720] were done by 53 institutes replied. The order of frequency of cell type in primary lung cancer was squamous [62.3%] / adeno [23.9%] / small [6.4%] / adenosquamous [3.0%], and in mediastinal tumor, neurogenic[27.l%] / thymoma [27.1%] / teratoma[26.4%] / congenital cystic[12.0%]. Surgery for tuberculosis was decreased to 15.8% of overall infectious disease from the recent 6 year`s average 35.7%. In general thoracic surgery, the single most frequent operation was closed thoracostomy[4,047 cases] for pleural pathology. The ratio of congenital to acquired heart disease was 2:1, and acyanotic to cyanotic was 3:1. The order of frequency of congenital acyanotic heart disease was VSD [45.6%] / ASD [25.6%] / PDA [20.4%] / PS [2.9%], and that of cyanotic heart disease was TOF [42.6%] / PA [12.9%] / TGA [9.9%] / DORV [8.8%]. In 1,364 cases of valvular surgery, single mitral pathology was the most frequent candidate[729 cases, 53.4%]. In 243 cases of coronary surgery, bypassing graft materials were great saphenous vein[41.6%], internal mammary [39.5%], and artificial vessel[18.9%]. There were no specific differences in aortic surgery, assisted device implantation, and antiarrhythmic surgery as compared to previous study. This nation-wide inquiry will be continued and reported annually by KTCS Society.