• Title/Summary/Keyword: Cyclopentaquinoline derivatives

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Synthesis and In Vitro Cytotoxicity of 4-Alkyl- or 4-Arylaminosubstituted Cyclopenta[c]quinoline Derivatives

  • Lee, Hee-soon;Lee, Jee-man;Yang, Sung-Il
    • Archives of Pharmacal Research
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    • v.24 no.5
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    • pp.385-389
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    • 2001

  • Twelve 4-substituted cyclopenta[c]quinoline derivatives were synthesized and evaluated in vitro cytotoxicity against four human cancer cell lines (HOP62, SK-OV-3, MD-MB-468 and T-47D). The compounds 6c and 6e bearing p-anisidine and pyrrolidine side chain were more active than the others.

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