• Journal of Electrochemical Science and Technology
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• 제9권4호
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• pp.276-281
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• 2018

High concentration of copper in mezcal, a representative Mexican spirituous alcoholic beverage, is a serious problem due to the damage that it may cause to human health. A cyclic voltammetry and square wave anodic stripping voltammetry study of copper (II) in three commercial mezcal samples based on glassy carbon electrode response was undertaken. The analysis was developed using a simulated matrix solution ($EtOH/H_2O$ (1:1), 0.1 M $LiClO_4$ and AcOH/AcONa 0.05 M/0.008 M), with Cu (II) concentrations in the range 0 - 1 ppm. Direct electrochemical analysis of mezcal samples was complicated by the presence of different organic compounds in the matrix. The analytical signal of Cu (II) in the spirituous was notably improved and the interferences caused by organic compounds were minimized, by diluting the mezcal samples 10% with $EtOH/H_2O$ (1:1) solution. An efficient quantification of Cu (II) was obtained from the calibration curve by the SWASV and using the internal standard method (Cd (II)) in commercial samples (1.2-6.7 ppm); the results were correlated satisfactorily with the values obtained by AAS.

• ETRI Journal
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• 제43권4호
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• pp.660-673
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• 2021

To efficiently use frequency resources, the next 6th generation mobile communication technology must solve the problem of out-of-band emission (OoBE) of cyclic prefix (CP) orthogonal frequency division multiplexing (OFDM), which is not solved in 5th generation technology. This study describes a new zero insertion technique to replace an existing filtering scheme to solve this internal problem in OFDM signals. In the development of the proposed scheme, a precoder with a two-dimensional structure is first designed by generating a two-dimensional mapper and using the specialty of each matrix. A spectral shaping technique based on zero insertion instead of a long filter is proposed, so it can be applied not only to long OFDM symbols, but also very short ones. The proposed method shows that the transmitted signal is completely blocked at the bandwidth boundaries of signals according to the current standards, and it is confirmed that the proposed scheme is ideal with respect to bit error rate (BER) performance because its BER is the same as that of CP-OFDM. In addition, the proposed scheme can transformed into a real time structure through vectorizing process with minimal complexity.

• ETRI Journal
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• 제45권1호
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• pp.45-59
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• 2023

In this paper, to optimize the average delay and power allocation (PA) for system users, we propose a resource scheduling scheme for wireless networks based on Cyclic Prefix Orthogonal Frequency Division Multiplexing (CP-OFDM) according to the first fifth-generation standards. For delay minimization, we solve a throughput maximization problem that considers CPOFDM systems with carrier aggregation (CA). Regarding PA, we consider an approach that involves maximizing goodput using an effective signal-to-noise ratio. An algorithm for jointly solving delay minimization through computation of required user rates and optimizing the power allocated to users is proposed to compose the resource allocation approach. In wireless network simulations, we consider a scenario with the following capabilities: CA, 256-Quadrature Amplitude Modulation, millimeter waves above 6 GHz, and a radio frame structure with 120 KHz spacing between the subcarriers. The performance of the proposed resource allocation algorithm is evaluated and compared with those of other algorithms from the literature using computational simulations in terms of various Quality of Service parameters, such as the throughput, delay, fairness index, and loss rate.

• ETRI Journal
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• 제45권2호
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• pp.213-225
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• 2023

Physical layer security (PLS) can improve the security of both terrestrial and nonterrestrial wireless communication networks. This study proposes a simplified framework for nonterrestrial cyclic prefixed orthogonal variable spreading factor (OVSF)-encoded multiple-input and multiple-output nonorthogonal multiple access (NOMA) systems to ensure complete network security. Various useful methods are implemented, where both improved sine map and multiple parameter-weighted-type fractional Fourier transform encryption schemes are combined to investigate the effects of hybrid PLS. In addition, OVSF coding with power domain NOMA for multi-user interference reduction and peak-toaverage power ratio (PAPR) reduction is introduced. The performance of $\frac{1}{2}$-rated convolutional, turbo, and repeat and accumulate channel coding with regularized zero-forcing signal detection for forward error correction and improved bit error rate (BER) are also investigated. Simulation results ratify the pertinence of the proposed system in terms of PLS and BER performance improvement with reasonable PAPR.

• ETRI Journal
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• 제46권3호
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• pp.392-403
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• 2024

Even though generalized frequency division multiplexing is an alternative waveform method expected to replace the orthogonal frequency division multiplexing in the future, its implementation must alleviate channel effects. Least-squares (LS), a low-complexity channel estimation technique, could be improved by using the discrete Fourier transform (DFT) without increasing complexity. Unlike the usage of the LS method, the DFT-based method requires the receiver to know the channel impulse response (CIR) length, which is unknown. This study introduces a simple, yet effective, CIR length estimator by utilizing LS estimation. As the cyclic prefix (CP) length is commonly set to be longer than the CIR length, it is possible to search through the first samples if CP is larger than a threshold set using the remaining samples. An adaptive scale is also designed to lower the error probability of the estimation, and a simple signal-to-interference-noise ratio estimation is also proposed by utilizing a sparse preamble to support the use of the scale. A software simulation is used to show the ability of the proposed system to estimate the CIR length. Due to shorter CIR length of rural area, the performance is slightly poorer compared to urban environment. Nevertheless, satisfactory performance is shown for both environments.

• 한국통신학회논문지
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• 제30권10C호
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• pp.1017-1026
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• 2005

버스트 방식 OFDM 시스템에서의 프레임 동기는 수신된 프레임의 시작 위치를 판단하고, 정확한 FPT-window 위치 추정을 위해 가장 우선적으로 수행되어야 한다. 유효 OFDM 심볼 내의 규정된 반복 패턴 또는 보호 구간의 상관을 이용하는 기존의 일반적인 프레임 동기 방식은 연속적으로 증가하다 감소하는 상관 출력 특성에 의해 정확한 프레임 시작 지점 검출이 어려우며, 수신 신호와 기준 신호 간의 상관 특성을 이용하는 방식은 주파수 옵셋으로 인한 성능 열화를 초래한다. 따라서, 본 논문에서는 프레임 동기 방식으로서 주파수 옵셋에 강인하고 정확한 프레임 시점 검출이 가능한 차동 상관(Differential Correlation) 방식을 기반으로 한 새로운 알고리즘을 제안하였다. 그러나, 일반적인 차동 신호의 상관 결과는 프리앰블의 반복 구조에 의해 다수의 Peak를 가지게 되며 이로 인하여 정확한 프레임 동기의 검출 성능이 열화된다. 본 논문에서는 이러한 차동 검출 방식의 단점을 보완하기 위하여 차동 신호 생성 시 반복되는 동일 패턴 구간의 샘플을 이용하여 단일 상관 Peak를 갖는 알고리즘을 제안한다. 또한 다중경로 페이딩 채널 환경에서 페이딩에 의한 프레임 시작 위치 검출 에러를 줄이기 위하여 신호 전력으로 상관 출력 값을 정규화하는 블록을 도입함으로써 고속 이동 채널 환경에서의 프레임 시작 지점 검출 확률을 높였다.

• 한국발생생물학회지:발생과생식
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• 제22권1호
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• pp.55-64
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• 2018

Previous studies showed that recombinant equine chorionic gonadotropin ($rec-eCG{\beta}/{\alpha}$) exhibits both follicle-stimulating hormone (FSH) and luteinizing hormone (LH)-like activities in rat LHR- and FSHR-expressing cells. In this study, we analyzed signal transduction by eelFSHR and eelLHR upon stimulation with $rec-eCG{\beta}/{\alpha}$ and native eCG. The cyclic adenosine monophosphate (cAMP) stimulation in CHO-K1 cells expressing eelLHR was determined upon exposure to different doses (0-1,450 ng/mL) of $rec-eCG{\beta}/{\alpha}$ and native eCG. The $EC_{50$ values of $rec-eCG{\beta}/{\alpha}$ and native eCG were 172.4 and 786.6 ng/mL, respectively. The activity of $rec-eCG{\beta}/{\alpha}$ was higher than that of native eCG. However, signal transduction in the CHO PathHunter Parental cells expressing eelFSHR was not enhanced by stimulation with both agonist $rec-eCG{\beta}/{\alpha}$ and native eCG. We concluded that $rec-eCG{\beta}/{\alpha}$ and native eCG were completely active in cells expressing eelLHR, similar to the activity in the mammalian cells expressing LHRs. However, $rec-eCG{\beta}/{\alpha}$ and native eCG did not invoke any signaling response in the cells expressing eelFSHR. These results suggest that eCG has a potent activity in cells expressing eelLHR. Thus, we also suggest that $rec-eCG{\beta}/{\alpha}$ can induce eel maturation by administering gonadotropic reagents (LH), such as salmon pituitary extract.

• 대한전자공학회논문지TC
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• 제46권5호
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• pp.95-103
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• 2009

본 논문에서는 cyclic shift diversity(CSD)가 적용된 프리앰블을 이용하는 MIMO-OFDM 기반의 IEEE 802.11n 무선랜 시스템을 위한 효율적인 심볼 동기 알고리즘을 제안한다. IEEE 802.11n 시스템에서는 다수개의 전송안테나를 통해 같은 프리앰블이 전송될 때 의도하지 않은 빔형성이 생성되는 것을 방지하고 송신안테나 다이버시티 이득을 얻기 위해 프리앰블에 CSD를 적용한다. 그런데, 이것은 수신단의 CSD 프리앰블의 cross-correlation 결과에서 다수개의 peak 값을 발생시키기 때문에, cross-correlation 방식을 이용하여 하나의 peak 위치를 검출한 후 심볼 동기를 수행하는 기존의 알고리즘을 이용할 경우 심볼 동기 오류가 발생되고, 패킷 검출과 AGC 완료 시점에 따라 심볼 동기의 성능이 좌우되는 문제를 발생시킨다. 따라서 본 논문에서는 CSD 프리앰블의 cross-correlation 특성, 패킷 검출과 AGC 완료 시점을 고려하여 LTS와 OFDM 심볼간의 경계 구역을 검출하는 기법과 신호 검출 시 임계점을 초과하는 지점의 정확도를 향상시킬 수 있는 재결정 모드 기법, 그리고 SNR별로 최적의 임계값을 적용할 수 있는 가변 임계값 기법 등으로 구성된 새로운 심볼 동기 알고리즘을 제안한다 제안하는 방식은 최대 주파수 오차가 존재하는 환경에서도 기존 방식에 비해 동기 실패율이 1%인 경우에는 4.3dB, 동기 실패율이 0.1%인 경우에는 18dB의 성능 향상을 이루는 것으로 나타났다. 이를 바탕으로, 제안하는 방식은 IEEE 802.11n 무선랜 시스템에 적합할 뿐만 아니라, CSD 프리앰블이 적용된 MIMO-OFDM 기반의 시스템에 확대 응용이 가능할 것으로 판단된다.

• The Korean Journal of Physiology and Pharmacology
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• 제4권6호
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• pp.445-453
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• 2000

The present investigation tested the hypothesis that the activation of protein kinase G (PKG) leads to a phosphorylation of $Ca^{2+}-activated$ potassium channel $(K_{Ca}\;channel)$ and is involved in the activation of $K_{Ca}$ channel activity in cerebral arterial smooth muscle cells of the rabbit. Single-channel currents were recorded in cell-attached and inside-out patch configurations of patch-clamp techniques. Both molsidomine derivative 3-morpholinosydnonimine-N-ethylcarbamide $(SIN-1,\;50\;{\mu}M)$ and 8-(4-Chlorophenylthio)-guanosine-3',5'-cyclic monophosphate $(8-pCPT-cGMP,\;100\;{\mu}M),$ a membrane-permeable analogue of cGMP, increased the $K_{Ca}$ channel activity in the cell-attached patch configuration, and the effect was removed upon washout of the drugs. In inside-out patches, single-channel current amplitude was not changed by SIN-1 and 8-pCPT-cGMP. Application of ATP $(100\;{\mu}M),$ cGMP $(100\;{\mu}M),$ ATP+cGMP $(100\;{\mu}M\;each),$ PKG $(5\;U/{\mu}l),$ ATP $(100\;{\mu}M)+PKG\;(5\;U/{\mu}l),$ or cGMP $(100\;{\mu}M)+PKG\;(5\;U/{\mu}l)$ did not increase the channel activity. ATP $(100\;{\mu}M)+cGMP\;(100\;{\mu}M)+PKG\;(5\;U/{\mu}l)$ added directly to the intracellular phase of inside-out patches increased the channel activity with no changes in the conductance. The heat-inactivated PKG had no effect on the channel activity, and the effect of PKG was inhibited by 8-(4-Chlorophenylthio)-guanosine-3',5'-cyclic monophosphate, Rp-isomer $(Rp-pCPT-cGMP,\;100\;{\mu}M),$ a potent inhibitor of PKG or protein phosphatase 2A (PP2A, 1 U/ml). In the presence of okadaic acid (OA, 5 nM), PP2A had no effect on the channel activity. The $K_{Ca}$ channel activity spontaneously decayed to the control level upon washout of ATP, cGMP and PKG, and this was prevented by OA (5 nM) in the medium. These results suggest that the PKG-mediated phosphorylations of $K_{Ca}$ channels, or some associated proteins in the membrane patch increase the activity of the $K_{Ca}$ channel, and the activation may be associated with the vasodilating action.

• The Korean Journal of Physiology and Pharmacology
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• 제20권1호
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• pp.9-14
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• 2016

Adenosine 3',5'-cyclic monophosphate (cAMP) participates in the regulation of numerous cellular functions, including the $Na^+-K^+$-ATPase (sodium pump). Ouabain, used in the treatment of several heart diseases, is known to increase cAMP levels but its effects on the atrium are not understood. The aim of the present study was to examine the effect of ouabain on the regulation of atrial cAMP production and its roles in atrial endothelin-1 (ET-1) secretion in isolated perfused beating rabbit atria. Our results showed that ouabain ($3.0{\mu}mol/L$) significantly increased atrial dynamics and cAMP levels during recovery period. The ouabain-increased atrial dynamics was blocked by KB-R7943 ($3.0{\mu}mol/L$), an inhibitor for reverse mode of $Na^+-Ca^{2+}$ exchangers (NCX), but did not by L-type $Ca^{2+}$ channel blocker nifedipine ($1.0{\mu}mol/L$) or protein kinase A (PKA) selective inhibitor H-89 ($3.0{\mu}mol/L$). Ouabain also enhanced atrial intracellular cAMP production in response to forskolin and theophyline ($100.0{\mu}mol/L$), an inhibitor of phosphodiesterase, potentiated the ouabain-induced increase in cAMP. Ouabain and 8-Bromo-cAMP ($0.5{\mu}mol/L$) markedly increased atrial ET-1 secretion, which was blocked by H-89 and by PD98059 ($30{\mu}mol/L$), an inhibitor of extracellular-signal-regulated kinase (ERK) without changing ouabain-induced atrial dynamics. Our results demonstrated that ouabain increases atrial cAMP levels and promotes atrial ET-1 secretion via the mitogen-activated protein kinase (MAPK)/ERK signaling pathway. These findings may explain the development of cardiac hypertrophy in response to digitalis-like compounds.