• BMB Reports
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• v.42 no.9
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• pp.593-598
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• 2009

Cell cycle progression is regulated by both transcriptional and post-transcriptional mechanisms. MicroRNAs (miRNAs) emerge as a new class of small non-coding RNA regulators of cell cycle as recent evidence suggests. It is hypothesized that expression of specific miRNAs oscillates orderly along with cell cycle progression. However, the oscillated expression patterns of many candidate miRNAs have yet to be determined. Here, we describe miRNA expression profiling in double-thymidine synchronized HeLa cells as cell cycle progresses. Twenty-five differentially expressed miRNAs were classified into five groups based on their cell cycle-dependent expression patterns. The cyclic expression of six miRNAs (miR-221, let-7a, miR-21, miR-34a, miR-24, miR-376b) was validated by real-time quantitative RT-PCR (qRT-PCR). These results suggest that specific miRNAs, along with other key factors are required for maintaining and regulating proper cell cycle progression. The study deepens our understanding on cell cycle regulation.

• Journal of Korean Institute of Industrial Engineers
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• v.33 no.1
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• pp.110-125
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• 2007

Various different types of yard cranes are used in container terminals. Examples are rubber tired gantry cranes,rail mounted gantry cranes, overhead bridge cranes, dual rail-mounted gantry cranes, and automated stacking cranes. The kinematics and handling characteristics of these yard cranes are different from each other. Ttiis study analyses charactehstics of generic types of yard cranes which represent various yard cranes m practice Demg used in several types of block layouts, Considering specifications of yard cranes and block layouts, expected cycle times and variances of the cycle time are estimated for different handling activities.

• Proceedings of the KSAR Conference
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• 2004.06a
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• pp.257-257
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• 2004

The study was carried out to investigate the effects of morphology, reproductive cycle, incubation time and activation of oocytes on in vitro maturation of cat oocytes and development of IVM/IVF embryos. 1. When recovered from ovaries collected at different stages of the reproductive cycle (inactive, follicular and luteal stage), the developmental rates of oocytes to GV and MI stage were 72.5% and 27.5%, 57.5% and 7.5%, 62.5% and 17.5%, respectively. (omitted)

• Journal of the Korean Society for Precision Engineering
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• v.24 no.8 s.197
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• pp.97-107
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• 2007

The present CNC machining system if without any CAM software has been limited to 2D or 2.5D plane cut using lines, arcs and curves. If the CNC is equipped with a surface interpolation module and a surface reorganizing module inside it, we can easily try 3D surface machining without aid of CAM software. The existing NURBS surface interpolator is simple and direct to use for a unit surface. However, it enables only machining of each reference surface individually even when machining a simple composite surface. In this paper, we propose a method which can unify and reorganize various reference surfaces with a newly defined NURBS surface cycle command: a multi-repetitive cycle command such as in a CNC turning center. We also introduce a reorganizing rule for reference surfaces using NURBS properties. The usefulness of the proposed method is verified through computer simulation.

• International Journal of Quality Innovation
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• v.2 no.2
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• pp.136-144
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• 2001

The Markov Chain approach is used to develop an economic adjustment model of a process whose quality can be affected by a single special cause, resulting in changes of the process mean by incorrect adjustment of the process when it is operating according to its capability. The $\bar{X}$ control chart is thus used to signal the special cause. It is demonstrated that the expressions for the expected cycle time and the expected cycle cost are easier to obtain by the proposed approach than by adopting that in Collani, Saniga and Weigang (1994). Furthermore, this approach would be easily extended to derive the expected cycle cost and the expected cycle time for the case of multiple special causes or multiple control charts. A numerical example illustrates the proposed method and its application.

• Proceedings of the Korean Society of Machine Tool Engineers Conference
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• 2002.10a
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• pp.387-392
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• 2002

It is very important to measure linear cycle plane positioning accuracy of NC lathes as they affect those of all other machines machined by them in industries. For example, if the linear cycle plane positioning accuracy of each axes directions is bad, the accuracy of works will be wrong and the change-ability will be bad in the assembly of machine parts. In this paper, computer software systems are organized to measure linear displacements of ATC(Automatic tool changer) of NC lathes using linear scale and time pulses comming out from computer in order to get data at constant time intervals from the sensors. And each sets of error data gotten from the test is expressed to plots by computer treatment and the results of linear cycle plane positioning error motion estimated to numerics by statistical treatments.

• International Journal of Air-Conditioning and Refrigeration
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• v.15 no.4
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• pp.175-181
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• 2007

A computer model of a high efficiency refrigeration system equipped with heat storage for reverse cycle-hot gas defrost (the stored heat is used during defrost cycle of the system) is presented. The model was developed based on both theoretical and empirical equations for the compressor, evaporator, condenser and the heat storage equipment. Simulations of the prototype system were carried out to investigate refrigeration system performance under various operating conditions during refrigeration cycles. The simulations of the evaporator during defrost cycles at 30 and $40^{\circ}C$ hot gas refrigerant temperature were also performed which resulted on shorter defrost time but only slight increase in defrost efficiency. These information on energy efficiency and the defrost time required are important in order to avoid excessive parasitic load and temperature rise of the refrigerated room.

• Advances in aircraft and spacecraft science
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• v.4 no.2
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• pp.203-218
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• 2017

This paper focuses on the computational study of nonlinear effects of unsteady aerodynamics for non-classical aileron buzz. It aims at a comprehensive investigation of the aileron buzz phenomenon under varying flow parameters using the describing function technique with multiple inputs. The limit cycle oscillatory behavior of an asymmetrical airfoil is studied initially using a CFD-based numerical model and direct time marching. Sharp increases in limit cycle amplitude for varying Mach numbers and angles of attack are investigated. An aerodynamic describing function is developed in order to estimate the variation of limit cycle amplitude and frequency with Mach number and angle of attack directly, without time marching. The describing function results are compared to the amplitudes and frequencies predicted by the CFD calculations for validation purposes. Furthermore, a limited sensitivity analysis is presented to demonstrate the potential of the approach for aeroelastic design.

• Proceedings of the ESK Conference
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• 1996.10a
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• pp.103-107
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• 1996

The menstrual cycle is repeated as long as a female is capable of bearing young, except during pregnancy and also for a certain length of time after the period of pregnancy. In this study, menstrual cycle and circadian rhythm of body temperature in young women are presented. Also, the specifications of different types in menstrual cycle and circadian rhythm are discussed to define the physiolosical temperature regulatuion system.

• Journal of the Korea Safety Management & Science
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• v.6 no.1
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• pp.173-185
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• 2004

The production using U-shaped line is studied. This research presents the relationship among machining time, cycle time and production rate in a U-shaped line. The U-shaped line produces shafts by automated machines. In this paper when any production rate is given the U-shaped line always satisfies the production rate. An algorithm is developed for the determination of cycle time, the number of machines and workers of the U-shaped line in order to minimize the total machine capacity and the number of workers for any given production rate. The U-shaped line was successfully designed by applying the proposed algorithm.