• Biotechnology and Bioprocess Engineering:BBE
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• v.8 no.6
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• pp.349-353
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• 2003

The physiological characteristics of cultures of very high cell mass (e.g. 10g cell mass/L), termed“ultrahigh cell density cultures”is reviewed. A close relationship was found between the length of the optical path (OP) in flat-plate reactors and the optimal cell density of the culture as well as its areal (g m$\^$-2/ day$\^$-1/) productivity. Cell-growth inhibition (GI) unfolds as culture density surpasses a certain threshold. If it is constantly relieved, a 1.0cm OP reactor could produce ca. 50% more than reactors with longer OP, e.g. 5 or 10cm. This unique effect, discovered by Hu et al. [3], is explained in terms of the relationships between the frequency of the light-dark cycle (L-D cycle), cells undergo in their travel between the light and dark volumes in the reactor, and the turnover time of the photosynthetic center (PC). In long OP reactors (5cm and above) the L-D cycle time may be orders of magnitude longer than the PC turnover time, resulting in a light regime in which the cells are exposed along the L-D cycle, to long, wasteful dark periods. In contrast, in reactors with an OP of ca. 1.0 cm, the L-D cycle frequency approaches the PC turnover time resulting in a significant reduction of the wasteful dark exposure time, thereby inducing a surge in photosynthetic efficiency. Presently, the major difficulty in mass cultivation of ultrahigh-density culture (UHDC) concerns cell growth inhibition in the culture, the exact nature of which is awaiting detailed investigation.

• Journal of The Korean Society of Integrative Medicine
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• v.6 no.2
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• pp.17-23
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• 2018

Purpose : The purpose of this study was to investigate whether the respiratory cycle and posture can modulate the autonomic nervous system. Methods : Thirty-two healthy men and women, aged 20-30 years, were enrolled in this study. We conducted 2-second and 6-second respiratory cycle with the subjects in standing, sitting, and supine positions, respectively. Their heart rate variability was measured in each position for both cycle lengths. Results : The low frequency/high frequency (LF/HF) ratio is derived from heart rate variability. In the 2-second respiratory cycles, the LF/HF ratios were highest in standing, sitting, and supine position in descending order. There was a significant difference in heart rate between standing and sitting positions (P<.005). In addition, there was a significant difference in heart rate between standing and supine position (P<.000). In the 6-second respiratory cycles, the LF/HF ratios were again highest in a standing, sitting, and supine position in descending order. However, posture was not found to make a significant difference in this case. Conclusion : Respiratory cycle and posture effectively modulated the autonomic nervous system. Further studies of the clinical application of these results should be conducted.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.27 no.5C
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• pp.500-505
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• 2002

In this paper, a novel architecture of programmable divider with fifty percent duty cycle output and programmable dividing number has been proposed. Through HSPICE simulation, a 900MHz frequency synthesizer with proposed frequency divider has designed in a standard 0.25$\mu\textrm{m}$ CMOS technology. To verify the operation of proposed frequency divider, a chip had been fabricated using 0.65$\mu\textrm{m}$ 2-poly, 3-metal standard CMOS processing and experimental result shows that the proposed frequency divider works well. The designed voltage controlled oscillator(VCO) has a center frequency of 900MHz, a tuning range of ${\pm}$10%, and a gain of 154MHz/V. The simulated frequency synthesizer performance has a settling time of 1.5${\mu}\textrm{s}$, a frequency range from 820MHz to 1GHz and power consumption of 70mW at 2.5V power supply voltage.

• International Journal of Air-Conditioning and Refrigeration
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• v.6
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• pp.27-35
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• 1998

An experimental study was performed to investigate the optimum cycle of an inverter heat pump as a function of frequency. The performance of the inverter heat pump with the rated cooling capacity of 4,141 W(3,550kcal/h) was measured with a variation of frequency, indoor and outdoor temperature, and length of capillary tube in the psychrometric test room. As a base case, the inverter heat pump with the standard capillary length of l,000mm(optimum size for the frequency of 60Hz) and ASHRAE Test condition "A" was tested by varying frequency from 30Hz to 80Hz. Then, the optimum cycles were investigated by varying the length of capillary tube at each frequency level of 30, 60 and 80Hz. Based on the experimental data, the change of system characteristics between the optimum and the base case were analyzed for each selected frequency level. Generally, for low frequency level(30Hz), the longer length of the capillary tube compared with the standard size showed the higher energy efficiency ratio(EER), while for high frequency level(80Hz) the shorter length of the capillary tube showed the higher EER.

• Proceedings of the IEEK Conference
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• 2003.07b
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• pp.1233-1236
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• 2003

This paper proposes a phase-locked loop (PLL) that achieves one-cycle lock acquisition by employing the lock-acquisition circuit (LAC). The LAC produces the initial analog voltage ( v$_{c}$ ) that corresponds to the input frequency. When the transfer curve of the LAC matches that of the voltage-controlled oscillator (VCO), one-cycle locking can be possible. By HSPICE simulations, the proposed LAC is proved to be applicable to any kinds of PLL [1][2][3].].

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2003.05a
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• pp.240-243
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• 2003

Combustion instability phenomena have been observed in various different combustion systems. For each specific combustion system, pressure fluctuations measured during high frequency combustion instability presented many different characteristics. High frequency instability occurring in a lean premixed gas turbine combustor mar be dominantly affected by a nonlinear relation between pressure oscillations and heat release rate fluctuations, and gas dynamics plays a crucial role in determining an amplitude of a limit cycle for a liquid rocket thrust chamber. Combustion instability phenomena manifest their inherent nonlinear characteristics. One is a limit cycle and the other bifurcation described by nonlinear time series analysis.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.10 no.4
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• pp.495-507
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• 1998

The transient characteristics of a 4.0㎾ inverter driven heat pump was investigated by theoretical and experimental studies. The heat pump used in this study consists of a high side scroll compressor and $\Phi$7 compact heat exchangers with two capillary tubes. A series of tests was peformed to examine the transient characteristics of heat pump in heating and cooling mode when the operating speed was varied from 30Hz to 102Hz. One of the major issues that has not been addressed so far is transient characteristics during speed modulation. A cycle simulation model has been developed to predict the cycle performance under frequency rise-up conditions, and the results of theoretical study were compared with the results of experimental study. The theoretical model was driven from mass conservation and energy conservation equations to predict the operation points of refrigerant cycle and the performances at various operating speeds. For transient conditions, the simulated results are in good agreement with the experimental results within 10%. The transient cycle migration of the liquid state refrigerant causes a significant dynamic change in system. Thus, the migration of refrigerant is the most important factor whenever An experimental analysis is performed or A simulation model is developed.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.31 no.8
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• pp.694-701
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• 2007

The applications of a transcritical $CO_2$ cycle into water heaters show advantages over conventional systems in the respect of power consumption and heating efficiency because the $CO_2$ cycle has a high compressor discharge temperature. Besides, the heating performance of the transcritical $CO_2$ cycle can be improved by optimizing operating conditions. In this study, the heating performance of a variable speed $CO_2$ heat pump was measured and analyzed by varying refrigerant charge amount, EEV opening, compressor frequency and outdoor temperature. As a result, the optimum normalized charge for heating was 0.226. The COPs at the compressor frequencies of 40, 50 and 60 Hz were 2.94, 2.75 and 2.25, respectively. The heating performance of the $CO_2$ cycle with charge amount was more sensitive than the cooling performance. Moreover, the heating performance was improved significantly by optimizing of compressor frequency and EEV opening.

• Journal of Power Electronics
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• v.6 no.2
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• pp.95-103
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• 2006

In this paper, a novel prototype of auxiliary switched capacitor assisted voltage source soft switching PWM Single-Ended Push Pull (SEPP) series capacitor compensated load resonant inverter with two auxiliary edge resonant lossless inductor snubbers is proposed and discussed for small scale consumer high-frequency induction heating (IH) appliances. The operation principle of this inverter is described by using switching mode equivalent circuits. The newly developed multi resonant high-frequency inverter using trench gate IGBTs can regulate its output AC power via constant frequency edge-resonant associated soft switching commutation by using an asymmetrical PWM control or duty cycle control scheme. The brand-new consumer IH products which use the newly proposed edge-resonant soft switching PWM-SEPP type series load resonant high-frequency inverters are evaluated using power regulation characteristics, actual efficiency vs. duty cycle and input power vs. actual efficiency characteristics. Their operating performance compared with some conventional soft switching high-frequency inverters for IH appliances is discussed on the basis of simulation and experimental results. The practical effectiveness of the newly proposed soft switching PWM SEPP series load resonant inverter is verified from an application point of view as being suitable for consumer high-frequency IH appliances.

• International Journal of Automotive Technology
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• v.8 no.3
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• pp.259-268
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• 2007

A knock detection circuit that is based on the signal of an accelerometer installed on the engine block of a spark ignition automotive engine has a band-pass filter with a certain frequency as a parameter to be calibrated. A new statistical method for the determination of the frequency which is the most suitable for the knock detection in real-time applications is proposed. The method uses both the cylinder pressure and block vibration signals and is divided into two steps. In both steps, a new recursive trigonometric interpolation method that calculates the frequency contents of the signals is applied. The new trigonometric interpolation method developed in this paper improves the performance of the Discrete Fourier Transformation, allowing a flexible choice of the size of the moving window. In the first step, the frequency contents of the cylinder pressure signal are calculated. The knock is detected in the cylinder of the engine cycle for which at least one value of the maximal amplitudes calculated via the trigonometric interpolation method exceeds a threshold value indicating a considerable amount of oscillations in the pressure signal; this cycle is selected as a knocking cycle. In the second step, the frequency analysis is performed on the block vibration signal for the cycles selected in the previous step. The knock detectability, which is an individual cylinder attribute at a certain frequency, is verified via a statistical hypothesis test for testing the equality of two mean values, i.e. mean values of the amplitudes for knocking and non-knocking cycles. Signal-to-noise ratio is associated in this paper with the value of t-statistic. The frequency with the largest signal-to-noise ratio (the value of t-statistic) is chosen for implementation in the engine knock detection circuit.