• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 1998년도 가을 학술발표대회 논문집(III)
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• pp.668-673
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• 1998

The specimen of current study has the same type with the 3-span slabs of Burns et al used in the study by Mojtahedi/Gamble, which laid a ground for the revision of the ACI318-77 code to the ACI 318-83 code. But those specimens was failed prematurely before it reached the ultimate strength which the specimen had. The reason is that bonded reinforcements were cut off where there is no need for the flexural reinforcement. As results. the slabs failed ultimately where the reinforcements was cut off. Thus, the tendon stresses of failure may have been much smaller than the values which culd reach if the bonded reinforcements were extended beyond the theoretical cut off points. On the based on the fact mentioned above. the specimens which had the same conditions as the specimens of Burns et al were used in the current study, but in which the reinforcements were distributed in a sequence for the reinforcements not to be cut anywhere in the 3-span. As a results, it was known that the current ACI code, revised by the result of Mojtahedi/Gamble's study, overestimated the effect of span/depth ratio on the members with high span/depth ratio. Thus it was concluded that the effect of span/depth ratio on the ultimate stress of unbonded tendon regulated by the current ACI code must be reconsidered and reevaluated.

• Journal of Preventive Medicine and Public Health
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• 제30권4호
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• pp.741-751
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• 1997

Measurement of blood lead (PbB) and blood zinc protoporphyrin (ZPP) are most common biological indices to identify the individual at risk for excess or the health sequences by lead exposure. Because PbB is known most important and reliable index of lead exposure, PbB is often regarded as a gold standard to detect lead exposure. But in Korea PbB is a secondary test item of detailed health check-up with positive finding of screening test in most occasion. Our lead standard requires all lead workers to take annual heath-check twice a year for investigation of their health effect due to lead exposure. Blood ZPP is one of most important index to detect high lead absorption in lead workers as a screening test. Measurement of blood ZPP is known ,well to correlate with PbB in steady state of exposure in most lead workers and is often used as a primary screening test to detect high lead absorption of lead workers with the advantage of simplicity, easiness, portability and low cost. The current cut-off criteria of blood ZPP for further detailed health check-up is $100{\mu}g/d\ell$ which is supposed to match the level of $40{\mu}g/d\ell$ of PbB according to our standard. Authors tried to investigate the validity of current criteria of cut-off level $(100{\mu}g/d\ell)$ of blood ZPP and possible another better cut-off level of it to detect the lead workers whose PbB level over $40{\mu}g/d\ell$. The subjects in our study were 212 male workers in three small scale storage battery industries. Blood ZPP, PbB and hemoglobin (Hb) were selected as the indices of lead exposure. The results were as follows. 1. The mean of blood ZPP, PbB and Hb in lead workers were $79.5{\pm}46.7{\mu}g/d\ell,\;38.7{\pm}15.1{\mu}g/d\ell,\;and\;14.8{\pm}1.2g/d\ell$, respectively. There were significant differences in blood ZPP, PbB and Hb by industry (P<0.01). 2. The percents of lead workers whose blood ZPP were above $100{\mu}g/d\ell$ in the group of work duration below 1, 1-4, 5-9 and above 10 years were 8.6%, 17.2%, 47.6%, and 50.0%, respectively. The percents of lead workers whose PbB were above $40{\mu}g/d\ell$ in those were 31.4%, 40.4%, 71.4%, and 86.4%, respectively. 3. The percents of lead workers whose PbB were below $40{\mu}g/d\ell$, $40-59{\mu}g/d\ell$ and above $60{\mu}g/d\ell$ were 54.7%, 34.9% and 10.4%, respectively. Those of lead workers whose blood ZPP were below $100{\mu}g/d\ell$, $100-149{\mu}g/d\ell$ and above $150{\mu}g/d\ell$ were 79.2%, 13.7% and 7.1%, respectively. 4. Simple linear regression of PbB on blood ZPP was statistically significant (P<0.01) and as PbB was $40{\mu}g/d\ell$, blood ZPP was $82.1{\mu}g/d\ell$. 5. While the highest sensitivity and specificity of blood ZPP test to detect lead workers with PbB eve. $40{\mu}g/d\ell$ were observed in the cut-off level of $50{\mu}g/d\ell$ and $100{\mu}g/d\ell$ of blood ZPP, respectively, the highest validity (sensitivity+specificity) of blood ZPP to detect lead workers with PbB over $40{\mu}g/d\ell$ was observed in the cut-off level of around $70{\mu}g/d\ell$ of blood ZPP. But even with optimal cut-off level of around $70{\mu}g/d\ell$ of blood ZPP, still 25.0% of false negative and 20.7% false positive lead workers were found. As the result of this study, it was suggested that reconsideration of current blood ZPP cut-off of our lead standard from $100{\mu}g/d\ell$ to somewhat lower level such as around $70{\mu}g/d\ell$ and the inclusion of PbB measurement as a primary screening test for lead workers was highly recommended for the effective prevention of lead workers.

• Asian Pacific Journal of Cancer Prevention
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• 제16권16호
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• pp.6923-6928
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• 2015

Background: Early detection of various kinds of cancers nowadays is needed including colorectal cancer due to the highly significant effects in improving cancer treatment. The aim of this study was to evaluate the potential value of adiponectin, visfatin and resistin as early biomarkers for colorectal cancer patients. Materials and Methods: Serum levels of adiponectin, visfatin and resistin were measured by a sandwich-enzyme-linked (ELISA) assay technique in 114 serum samples comprising 34 patients with colorectal cancer (CRC), 27 with colonic polyps (CP), 24 with inflammatory bowel disease (IBD) and 29 healthy controls. The diagnostic accuracy of each serum marker was evaluated using receiver-operating characteristic (ROC) curve analysis. Results: The mean concentration of adiponectin was significantly higher in CRC and CP groups than IBD and control groups (P-value <0.05). Also the mean concentration of serum resistin was significantly elevated in the IBD and control groups compared to CRC and CP groups (P-value = 0.014). However, no significant difference was noted in patients of the CRC and CP groups. On the other hand, the mean concentration of visfatin was significantly elevated in CRC and control groups compared to CP and IBD groups (P-value = 0.03). ROC analysis curves for the studied markers revealed that between CRC and IBD groups serum level of adiponectin had a sensitivity of 76.7% and a specificity of 76% at a cut off value of 3940, +LR being 3.2 and -LR 0.31 with AUC 0.852, while serum level of adiponectin between CP and IBD had a sensitivity of 77.8% and a specificity of 75% at a cut off value of 3300, with +LR=3.11 and -LR = 0.3 with AUC 0.852. On the other hand the serum level of visfatin between CRC and CP groups had a sensitivity of 65.5% and a specificity of 66.7 at a cut off value of 2.4, +LR being 1.67 and -LR 0.52 with AUC 0.698. Also the serum level of resistin had a sensitivity of 62.5% and a specificity of 70.3% at a cut off value of 24500, with +LR=2.1 and -LR = 0.53 with AUC 0.685 between control and other groups. On the other hand by comparing control vs CP groups resistin had a sensitivity of 81.8% and a specificity of 70.8% at a cut off value of 17700, with +LR=2.8 and -LR = 0.26 with AUC 0.763 while visfatin had a sensitivity of 68.2% and a specificity of 70.8% at a cut off value of 2.7, with +LR=2.34 and -LR = 0.0.45 with AUC 0.812. Conclusions: These findings support potential roles of adiponectin, visfatin and resistin in early detection of CRC and discrimination of different groups of CRC, CP or IBD patients from normal healthy individuals.

• Journal of Preventive Medicine and Public Health
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• 제28권3호
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• pp.640-650
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• 1995

After the introduction of National Medical Insurance in 1989, the medical demand has rapidly increased. The impact of increased medical demand was followed by an increase in the number of claims in need of review. We studied a new, fair method for reducing the number of claims reviewed. We analysed 90,583 outpatient claims submitted between September and October; claims were made for services given August of 1994. We finally suggested a screening system for claims review using a statistical method of discriminant analysis of the medical costs. The results were as follows. 1. In the cut-off group, age, days of medication, number of hospital or clinic visits, and total charge were significantly high. The cut-off rates according to the hospital-type and existence of accompanied disease were significantly different 2. According to ICD, the cut-off rate was highest in peripheral enthesopathies and allied syndromes(20.76%), lowest in acute sinusitis(0.93%). The mean charges were significantly different according to ICD and existence of cut-off. 3. We build discriminant functions by ICD with such discriminant variables as patient age, sex, existence of accompanied disease, number of hospital or clinic visits, and 9 detailed hospital or clinic charges included in claim. 4. We applied the discriminant function for screening those claims that were expected to be cut-off. The sensitivities comprised from 40% to 70%, and specificities from 70% to 95% by ICD. Acute rhinitis had highest sensitivity(100.00%) and other local infections of skin and subcutaneous tissue had highest specificity(98.45%). The expected number of cut-off was 17,762(19.61%). The total sensitivity was 49.62%, the total specificity was 82.57% and the error rate was 19.66%. We lacked economic analysis such as cost-benefit analysis. But, if the new method of screening claims using discriminant analysis were applied, the number of claims in need of review will reduce considerably.

• 대한토목학회논문집
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• 제12권4_1호
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• pp.129-136
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• 1992

압력식(壓力式) 파고계(波高計)에서 측정(測定)되어진 압력파형(壓力波形)으로부터 수위변동(水位變動)을 추정(推定)하는 방법(方法)에 대해서 1) Fast Fourier Transform Method(FFTM), 2) Local Curvature Method(LCM), 3) Individual Wave Method(IWM)의 3가지 방법(方法)을 비교(比較)하여, 천해역(淺海域)에 있어서의 파랑측정(波浪測定)에 대한 압력식(壓力式) 파고계(波高計)의 적용성(適用性)에 대해 검토(檢討)했다. 그 결과(結果) 다음과 같은 결론(結論)을 얻었다. 1) 측정(測定)되어진 압력파형(壓力波形)으로부터 수위변동(水位變動)을 추정(推定)할 때에 사용(使用)되어지는 이론선형응답함수(理論線形應答函數)(Hp=coshkh/coshk(h+z)의 적용가능범위(適用可能範圍)(cut-off-frequency)는 $kh{\leq}3.0$이다. 그리고 kh > 3.0의 영역(領域)에 있어서의 이론선형응답함수(理論線形應答函數)는 일정치(一定値)를 부여함으로써 매우 정도높은 수위변동(水位變動)을 얻을 수 있다. 2) LCM에 의한 수위변동(水位變動)의 변환(變換)에 있어서는 측정(測定)된 압력파형(壓力波形)속에 포함되어 있는 단주기파(短週期波)들에 의해 크게 영향(影響)을 받는다. 그러므로, kh > 1.5인 영역(領域)의 압력변동(壓力變動)을 무시할 필요(必要)가 있다. 3) FFTM 및 IWM에 의해 추정(推定)되어진 통계량(統計量)의 재현성(再現性)은 양호하고, 특(特)히 평균주기(平均週期)의 재현성(再現性)으로부터 비선형성(非線型性)이 강한 영역(領域)에 있어서는 IWM이 유효(有效)한 수단이라고 사려되어진다.

• 지구물리와물리탐사
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• 제12권1호
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• pp.154-162
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• 2009

단극 및 쌍극 음원을 이용하여 S파속도 결정에 큰 영향을 미치는 분산특성을 연구하였다. 이를 위하여 동일한 물성을 가지면서 공경을 달리하는 3종류의 시추공모형(${\Phi}520\;mm$. ${\Phi}150\;mm$and ${\Phi}76\;mm$)을 중심으로 이른 분산곡선을 구하고 공경과 공내검층기 존재 유무에 따른 분산 특성의 변화를 비교 분석하였다. 분산곡선의 형태는 단극음원에서 시추공 내의 공내검층기 유무에 크게 영향을 받지 않고 비슷하게 나타난 반면에 쌍극음원에서는 공내검층기 유무가 큰 차이를 보였다. 반면에 절단주파수에서는 쌍극음원에 비하여 단극음원에서 공내검층기 유무에 따른 차이가 크며 특히 소구경 시추공에서 큰 차이를 보여 단극음원을 이용한 토목시추공 음파검층에서 주파수 선택이 매우 중요한 변수가 될 수 있음을 보였다. 수치모델링결과, 절단주파수와 시추공경과의 관계는 기존에 알려진 일반적인 반비례 관계보다는 지수함수적으로 감소하는 관계임을 확인하였으며, 분산모드의 종류나 공내검층기 유무에 상관없이 각 환경에 있어서의 절단주파수 값을 지수함수로 표시할 수 있었다. 특정 시추공 환경에서의 분산곡선 및 분산특성들은 과거 연구결과들로부터 비교적 잘 알려져 있지만 분산곡선의 직접 비교에 의하여 분산특성에 미치는 시추공경과 공내측정기 영향을 보다 구체적으로 밝힐 수 있었다.

• 전기화학회지
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• 제7권1호
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• pp.32-37
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• 2004

리튬 이차전지의 음극재료로서 천연흑연의 충방전 속도에 따른 용량특성을 조사하였다 정전류 조건에서 $0.0-2.0V(vs. Li/Li^+)$의 범위에서 충방전 하였을 때, 충전전류가 증가할수록 충전반응의 과전압이 증가하여 $Li^+$이온이 충분히 삽입되지 못한 상태에서 컷오프 전압(0.0 V)에 도달하기 때문에 충전용량은 충전전류의 크기가 클수록 감소하였다. 한편, 방전전류가 증가함에 따라 방전반응의 과전압도 증가하여 0.0-0.3V범위에서 방전반응이 일어나나 방전 컷오프 전압(2.0 V)과는 격차가 커서 $Li^+$이온이 탈리되지 못한 상태에서 방전 컷오프에 도달하는 현상은 없기 때문에 방전용량이 방전전류의 크기에 영향을 받지 않았다. 충전전류가 증가함에 따라 부반응인 리튬 전착반응의 과전압도 증가하므로 충전 컷오프 전압을 0.0V 이하로 낮출 수 있었다. 그러나 $Li^+$이온의 삽입반응에 비해 전착반응의 저항이 적어 충전전류에 따른 전착반응의 과전압 증가에는 한계가 있었다. 1C조건에서 -0.04V까지 충전 z컷오프 전압을 낮추었을 때 리튬의 전착반응은 없었고, 이로부터 약 $11\%$의 방전용량을 증가시킬 수 있었다.

• 한국지반공학회논문집
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• 제33권11호
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• pp.73-82
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• 2017

최근 재래식 가물막이의 문제점을 해결하기 위하여 새로운 해상 대형원형강재 가물막이 공법이 제안되었다. 본 연구에서는 침투 흐름해석을 수행하여 대형원형강재의 파이핑 현상에 대하여 분석하였다. 흐름해석에서 균질한 지반조건과 정상상태 흐름조건을 적용하였다. 흐름 조건의 경우 2차원 조건(2-D), 2차원 흐름집중 조건(2-DC), 그리고 2차원 축대칭 조건을 서로 비교하였다. 그 결과, 축대칭 흐름조건의 침투속도가 2-D와 2-DC 조건의 흐름속도와 비교하여 각각 1.5배와 2배 큰 침투속도를 보여주였다. 즉, 대형원형강재는 원형형상의 벽체 중심으로 흐름이 집중되므로 2차원 축대칭 흐름조건을 적용하였다. 대형원형강재의 직경, 벽체의 지중 근입깊이, 그리고, 벽체 내외부의 수위차 등을 변화시키며 변수연구를 수행하였다. 파이핑 안전율에 영향을 주는 유출동수경사는 벽체의 지중 근입깊이와 강재직경이 증가할수록 감소하였다. 본 연구에서는 다양한 변수조건에서 안전율과 유출동수경사를 산정할 수 있는 간이설계도표를 제안하였다. 그리고, 최종적으로 대형원형강재의 간이 설계에 적용할 수 있는 유출동수경사 산정식을 제안하였다.

• 한국방사선학회논문지
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• 제13권2호
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• pp.201-207
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• 2019

본 연구는 갑상샘 초음파에서 K-TIRADS 분류와 K-TIRADS 분류에 따른 Different risk group의 조합을 이용한 방법이 양성과 악성 결절의 감별진단에 유용한지를 평가하였다. 갑상샘 초음파를 시행한 210명을 대상으로 하였으며, 세침흡인세포검사 결과를 바탕으로 후향적인 분석을 하였다. 갑상샘 결절의 양성과 악성에 따른 K-TIRADS와 Different risk group의 점수체계의 차이 분석은 카이제곱 검정을 하였다. ROC 곡선 분석을 통해 악성 결절의 예측을 위한 K-TIRADS 점수와 Different risk group의 최적 cut off 값을 결정하였다. 양성과 악성 결절 군의 분류에 따른 K-TIRADS와 Different risk group의 차이검증 결과에서 각각 통계적으로 유의한 차이를 보였다(p=.001). ROC 곡선 분석에서 양성과 악성 결절의 예측을 위한 K-TIRADS에 따른 점수분류에서는 AUC 0.786, Cut-off value> 2를 나타내었으며, Different risk group에서는 AUC 0.640, Cut-off value> 2로 결정되었다(p=.001). 갑상샘 초음파에서 결절을 발견했을 때 양성과 악성 갑상샘 결절을 감별하는 데 도움을 주는 K-TIRADS에 따른 분류체계가 Different risk group에 따른 분류체계보다 갑상샘 결절의 감별진단에 도움을 줄 것으로 생각하며 K-TIRADS에 따른 분류체계를 적용하면, 불필요한 세포 검사를 줄일 수 있고, 악성 결절의 조기발견에 도움이 될 것으로 생각된다.

• 대한통합의학회지
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• 제9권3호
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• pp.37-45
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• 2021

Purpose : This study aimed to present normative data and cut-off points for older Korean adults completing the Montreal Cognitive Assessment - Korean (MoCA-K), which is used as a screening test for mild cognitive impairment in Korea. Methods : A total of 195 healthy adults ≥60 years were recruited. All participants completed the MoCA-K and the Korean - Mini-Mental State Examination (MMSE-K) to assess their cognitive function. Participants were divided into six groups based on their age: 60-64 years, 65~69 years, 70~74 years, 75~79 years, 80~84 years, and 85~89 years. Results : The results revealed that MoCA-K score decreased significantly with age (mean score ± standard deviation [SD]; 27.63±2.80 in subjects aged 60~64 years; 27.00±2.39 in subjects aged 65~69 years; 24.94±2.96 in subjects aged 70~74 years; 24.74±3.37 in subjects aged 75~79 years; 22.59±4.72 in subjects aged 80~84 years; and 18.83±5.38 in subjects aged 85~89 years; p<.001). Additionally, MoCA-K score also increased significantly with educational level (mean score±standard deviation [SD]; 19.95±4.78 in no formal education group; 24.95±2.22 in elementary school graduated group; 26.35±2.72 in middle school graduated group; 28.32±1.36 in high school graduated group; and 28.50±1.51 in more than college graduated group; p<.001). The optimal cut-off points were 24/25 for 60~69 years old group, 21/22 for 70~79 years old group, 17/18 for 80~84 years old group, and 13/14 for 85~89 years old group. The optimal cut-off points were 15/16 for individuals who were illiterate, 22/23 for individuals with 6 years of education, 22/24 for individuals with 9 years of education, and 26/27 for individuals with 12 or more years of education. Conclusions : This study presents normative data and cut-off points for the MoCA-K in older Korean adults. This data will facilitate more accurate detection and follow-up of the risk of mild cognitive impairment in this population, taking into consideration age and education. Future studies are required that should focus on the cut-off score on the level of education according to age.