• 한국생산제조학회지
• /
• 제25권1호
• /
• pp.48-53
• /
• 2016

An EMAT can be used to reliably detect defects as it serves as a non-contact transducer with the ability to transmit ultrasonic waves into specimens without couplant. Moreover, an EMAT can easily generate desired waves by altering the design of the coil and magnet. This study proposes an SH-EMAT to evaluate the integrity of the TIG welding part. A stainless steel was welded using the TIG welding method. The welding current was varied to create artificial defects. Both the PA-UT and the RT were applied to verify the defect size. The experimental results generated by using the EMAT were compared with those methods. The amplitude was observed to decrease with an increase in the defect size. These results confirmed that the presence of defects can be reliably detected by attenuation of signal amplitude. The results demonstrated that the proposed method is suitable for evaluating the integrity of TIG welding.

• 한국분말재료학회지
• /
• 제16권3호
• /
• pp.180-184
• /
• 2009

In this paper, the electrochemical non-enzyme immunosensor has been developed for the determination of salmonella antigen, using inverse voltammetry. For the estimation of salmonella antigen concentration, the $Fe_3O_4$ nanoparticles synthesized by microemulsion method were conjugated with salmonella antigen. Then, the immunocomplex between antibody immobilized on the transducer surface and antigen containing a magnetic nanoparticles was formed. From the linear relationship between the reduction peak current of Fe(III) and salmonella antigen concentration, it is suggested that the electrochemical non-enzyme biosensor is applicable to detect salmonella antigen in the concentration range of $10^1-10^5$ CFU/ml.

• KSBB Journal
• /
• 제13권1호
• /
• pp.52-57
• /
• 1998

The present work proposes a simple electrochemical method applicable to any immobilization processes of oxidase using a Clark type oxygen electrode as a base transducer. The present work suggests an optimal immobilization technique among three different methods of glucose oxidase(GOD) onto one side of $37[\mu}$mthick blend membranes, composed o 80% of cellulose triacetate and 20% of polycaprolactone, on the basis of the maximum Michaelis-Menten parameter(Vm) determined by either steady state or transient analyses. The electrode system was made of disk type gold cathode(4mm diameter) and Ag/AgCl anode. One side of the blend membrane was in contact with the cathode surface while the other side was immobilized with GOD either in covalent-bond or cross-linked forms, the latter being covered by $25{\mu}$m thick dialysis membrane of cellulose acetate. The resultant current density was on-line monitored by a potentiostat while glucose level was varied from 1 to 20 mM. The present study shows that direct cross-linking of GOD with glutaraldehyde was mostly preferred for fabrication of glucose sensor, on the basis of resultant kinetic parameters from either steady state or transient analyses.

• 전기전자학회논문지
• /
• 제1권1호
• /
• pp.1-10
• /
• 1997

It is well-known that rectangular bulk-Si sensors prepared by etch or epi etch-stop micromachining technology are already in practical use today, but the conventional bulk-Si sensor shows some drawbacks such as large chip size and limited applications as silicon sensor device is to be miniaturized. We consider a circular-shape SOI(Silicon-On-Insulator) micro-cavity technology to facilitate multiple sensors on very small chip, to make device easier to package than conventional sensor like pressure sensor and to provide very high over-pressure capability. This paper demonstrates the cross-functional results for stress analyses(targeting $5{\mu}m$ deflection and 100MPa stress as maximum at various applicable pressure ranges), for finding permissible diaphragm dimension by output sensitivity, and piezoresistive sensor theory from two-type SOI structures where the double SOI structure shows the most feasible deflection and small stress at various ambient pressures. Those results can be compared with the ones of circular-shape bulk-Si based sensor$^{[17]}. The SOI micro-cavity formed the sensors is promising to integrate with calibration, gain stage and controller unit plus high current/high voltage CMOS drivers onto monolithic chip.

• 한국광학회지
• /
• 제12권4호
• /
• pp.257-262
• /
• 2001

상용 반도체 레이저 다이오드에 Littman형 외부공진기를 결합하여 파장기변 레이저 다이오드 시스템을 제작하였다. 0차 출력광은 단일종모드로 동작하여 CFP의 분해능인 9MHz이내의 선폭을 예상할 수 있었으며 다이오드 구동전류 140mA 및 동작온도 $25^{\circ}C$의 조건하에서 거울을 수동나사로 회전시키는 성긴 튜닝(coarse tuning)시 3.475nm 의 파장가변 범위를 보였으며 PZT(piezoelectric transducer)에 200Hz의 톱니파 전압을 인가해서 거울을 회전시키는 미세튜닝(fine tuning)시 0.042nm의 범위내에서 연속적인 파장가변이 가능하였다.

• 소성∙가공
• /
• 제23권7호
• /
• pp.413-418
• /
• 2014

The current study presents experimental and numerical results on the effect of ultrasonic vibrations on a cylindrical cup drawing of a cold rolled steel sheet(SPCC). An experimental apparatus, which can superimpose high frequency oscillations during deep drawing, was constructed by installing on the tooling ultrasonic vibration generators consisting of a piezoelectric transducer and a resonator. Conventional and vibration-assisted cylindrical deep drawing tests were conducted for various drawing ratios, and the limiting drawing ratios(LDR) for both methods were compared. To evaluate quantitatively the contribution from the ultrasonic vibrations to the reduction of friction between tools and material finite element analyses were conducted. Through a series of parametric analyses, the friction coefficients, which minimized the differences of punch load data between the experiments and simulations, were determined. The results show that the application of ultrasonic vibration effectively improves the LDR by reducing the friction between the tools and the material.

• 한국구조물진단유지관리공학회 논문집
• /
• 제5권3호
• /
• pp.173-180
• /
• 2001

In the past few years, the nondestructive inspection technology has greatly developed due to the increased necessity to gain a complete understanding of the bridge behavior. Especially, the deformations of bridges contain a lot of informations about its health state. By measuring these deformations it is possible to analyze the loading and aging behavior of the structure. However, the current, methods (such as LVDT, dial gage, optical displacement transducer, etc) are often of changeable application on site and have the limitations of installation. In this paper, the classical beam theory was reviewed and the deflections of structure are estimated using measured strain which is easy to acquire. The applicability of this algorithm is verified by laboratory(simple reinforced concrete beam) and field test. By this test, we proposed correction factor to estimate deflection of reinforced concrete beam after cracking, and analyze about the generation of correction factor. Also fiber optic sensors as well as resistive strain gages were installed in the concrete beams to establish the applicability of fiber optic sensors in the field of civil engineering.

• 조명전기설비학회논문지
• /
• 제17권4호
• /
• pp.50-56
• /
• 2003

본 논문에서는 유입변압기 진단을 목적으로 부분방전시 발생하는 여러 가지 물리적 화학적 현상중 초음파를 검출하기 위하여 광섬유 Mach-Zehnder 간섭계를 구성하였다. 구성된 광섬유 센서의 초음파 검출 평가 실험을 실시하고, 절연유 중에 배치한 침-평판전극에 교류 고전압을 인가하여 방전시 발생하는 초음파를 측정하고 퓨리에 변환 및 wavelet 변환을 이용한 데이터 분석 결과를 나타냈다.

• Journal of Korean Medical Science
• /
• 제33권44호
• /
• pp.279.1-279.16
• /
• 2018

Magnetic resonance-guided focused ultrasound (MRgFUS) is a new emerging neurosurgical procedure applied in a wide range of clinical fields. It can generate high-intensity energy at the focal zone in deep body areas without requiring incision of soft tissues. Although the effectiveness of the focused ultrasound technique had not been recognized because of the skull being a main barrier in the transmission of acoustic energy, the development of hemispheric distribution of ultrasound transducer phased arrays has solved this issue and enabled the performance of true transcranial procedures. Advanced imaging technologies such as magnetic resonance thermometry could enhance the safety of MRgFUS. The current clinical applications of MRgFUS in neurosurgery involve stereotactic ablative treatments for patients with essential tremor, Parkinson's disease, obsessive-compulsive disorder, major depressive disorder, or neuropathic pain. Other potential treatment candidates being examined in ongoing clinical trials include brain tumors, Alzheimer's disease, and epilepsy, based on MRgFUS abilities of thermal ablation and opening the blood-brain barrier. With the development of ultrasound technology to overcome the limitations, MRgFUS is gradually expanding the therapeutic field for intractable neurological disorders and serving as a trail for a promising future in noninvasive and safe neurosurgical care.

• 대한병리학회지
• /
• 제52권6호
• /
• pp.363-368
• /
• 2018

Background: Vitiligo is a chronic autoimmune disease in which the destruction of melanocytes causes white spots on the affected skin. Janus kinase (JAK) is a family of intracellular, non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-signal transducer and activator of transcription pathway. The aim of the present study is to explore the possible role of JAK1 in the pathogenesis of vitiligo using immunohistochemical methods. Methods: The current study was conducted in a sample of 39 patients who presented with vitiligo and 22 healthy individuals who were age and sex matched as a control group. We used immunohistochemistry to evaluate JAK1 status (intensity and distribution) and assess the percentage of residual melanocytes using human melanoma black 45 (HMB45). Results: Intense and diffuse JAK1 expression was significantly more likely to indicate vitiliginous skin compared to normal skin (p<.001). Strong and diffuse JAK1 expression was associated with short disease duration, female sex, and lower percentage of melanocytes (detected by HMB45) (p<.05). Conclusions: JAK1 may be involved in the pathogenesis of vitiligo, as indicated by intense and diffuse expression compared to control and association with lower percentage of melanocytes detected by HMB45 immunostaining.