• Korean Journal of Construction Engineering and Management
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• v.24 no.6
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• pp.81-90
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• 2023

Climate change has resulted in increased frequency and intensity of heat waves, which poses a significant threat to the health and safety of construction workers, particularly those engaged in labor-intensive and heat-stress vulnerable working environments. To address this challenge, this study aimed to propose an interpretable machine learning approach for forecasting personal heat strain by considering the cumulative effect of heat exposure as a situational variable, which has not been taken into account in the existing approach. As a result, the proposed model, which incorporated the cumulative working time along with environmental and personal variables, was found to have superior forecast performance and explanatory power. Specifically, the proposed Multi-Layer Perceptron (MLP) model achieved a Mean Absolute Error (MAE) of 0.034 (℃) and an R-squared of 99.3% (0.933). Feature importance analysis revealed that the cumulative working time, as a situational variable, had the most significant impact on personal heat strain. These findings highlight the importance of systematic management of personal heat strain at construction sites by comprehensively considering the cumulative working time as a situational variable as well as environmental and personal variables. This study provided a valuable contribution to the construction industry by offering a reliable and accurate heat strain forecasting model, enhancing the health and safety of construction workers.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.7 no.1
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• pp.43-54
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• 1987

Cumulative damage characteristics of concrete, on which rapetitive loads are applied, are investigated. Preliminarily, a series of uniaxial compression tests on cylindrical specimens of plain concrete is carried out to find out that, among various factors, stress levels of repetitive loadings and loading order are the most governing factors of cumulative damage of concrete. Based on this preliminary study, fatigue tests are carried out applying two levels of stresses, stepwisely. As a result, it is found that characteristics of cumulative damage of concrete are governed by nonlinear relationships and do not follow Miner's linear theory. It is also observed that cumulative damage characteristics and static strengths of concrete vary with loading history of stresses. Empirical equations which may be useful in predicting fatigue characteristics and remaining life of concrete stuctures are proposed for concrete subjected two stress levels.

• Journal of Applied Reliability
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• v.16 no.2
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• pp.118-124
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• 2016

Purpose: The purpose of this paper is to suggest an environmental test plan for reducing early failure. Methods: We study the preferred test design and tests that are performed substantially in the company. We investigate the environmental profile on the actual supply chain and identify the effectiveness for this test design. Results: Proposed sequential test designed to implement the supply chain on the environment profile showed more effective results compared to existing tests. Conclusion: Suggested sequential test in this paper will be an effective guidance for the given environment test.

• Journal of The Korean Society of Grassland and Forage Science
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• v.11 no.4
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• pp.209-214
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• 1991

The germination of seeds is developmentally complex process requiring water uptake, which is regulated by both genotypic and environmental factors. The present study was undertaken to determine the difference in germination characteristics, and to compare the ability of the logistic and Weibull functions to describe the cumulative germination curve when two levels of osmotic potential(0, -5 bar) were put to seeds of alfalfa, tall fescue, orchardgrass, and Kentucky bluegrass. The effects of grass type, osmotic potential, and their interaction on the total germination and coefficient of germination velocity were significant(P<0.01). The Weibull equation for predicting percent cumulative germination curve of alfalfa had significantly lower residuals than the logistic equation regardless of osmotic potential(P<0.01), indicating that the Weibull equation was more efficient than the logistic equation to fit the data of the percent cumulative germination of alfalfa. The rate parameter from the logistic equation was decreased under water stress, whereas the scale and shape parameters were increased. There were significant differences in days to 20% germination estimated from the logistic and Weibull equations.

• International Journal of Highway Engineering
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• v.13 no.4
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• pp.103-115
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• 2011

Concrete slab curls and warps due to the uneven distribution of temperature and moisture and as the result, internal stress develops within the slab. Therefore, environmental loads must be considered in addition to the traffic loads to predict the lifespan of the concrete pavement more accurately. The strength of the concrete slab is gradually decreases to a certain level at which fatigue cracking is generated by the repetitive traffic and environmental loadings. In this study, a new fatigue regression model was developed based on the results from previously performed studies. To verify the model, another laboratory flexural fatigue test program which was not used in the model development, was conducted and compared with the predictions of other existing models. Each fatigue model was applied to analysis logic of cumulative fatigue damage of concrete pavement developed in the study. The sensitivity of cumulative fatigue damage calculated by each model was analyzed for the design factors such as slab thickness, joint spacing, complex modulus of subgrade reaction and the load transfer at joints. As the result, the model developed in this study could reflect environmental loading more reasonably by improving other existing models which consider R, minimum/maximum stress ratio.

• BMB Reports
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• v.48 no.4
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• pp.209-216
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• 2015

Stress is now recognized as a universal premorbid factor associated with many risk factors of various chronic diseases. Acute stress may induce an individual's adaptive response to environmental demands. However, chronic, excessive stress causes cumulative negative impacts on health outcomes through "allostatic load". Thus, monitoring the quantified levels of long-term stress mediators would provide a timely opportunity for prevention or earlier intervention of stressrelated chronic illnesses. Although either acute or chronic stress could be quantified through measurement of changes in physiological parameters such as heart rate, blood pressure, and levels of various metabolic hormones, it is still elusive to interpret whether the changes in circulating levels of stress mediators such as cortisol can reflect the acute, chronic, or diurnal variations. Both serum and salivary cortisol levels reveal acute changes at a single point in time, but the overall long-term systemic cortisol exposure is difficult to evaluate due to circadian variations and its protein-binding capacity. Scalp hair has a fairy predictable growth rate of approximately 1 cm/month, and the most 1 cm segment approximates the last month's cortisol production as the mean value. The analysis of cortisol in hair is a highly promising technique for the retrospective assessment of chronic stress. [BMB Reports 2015; 48(4): 209-216]

• Toxicological Research
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• v.19 no.3
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• pp.161-172
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• 2003

Explanted mammalian cells perform a limited number of cell division in vitro and than are arrested in a state known as replicative senescence. Such cells are irreversibly blocked, mostly in the G1 phase of cell cycle, and are no longer sensitive to growth factor stimulation. Thus replicative senescence is defined as a permanent and irreversible loss of replicative potential of cells. For this characteristic, replicative senescence seems to evolve to protect mammalian organism from cancer. However, senescence also contributes to aging. It seems to decrease with age of the cell donor and, as a form of cell senescence, is thought to underlie the aging process. Extensive evidence supports the idea that progressive telomere loss contributes to the phenomenon of cell senescence. Telomeres are repetitive structures of the sequence (TTAGGG)n at the ends of linear chromosomes. It has been shown that the average length of telomere repeats in human somatic cells decreases by 30∼200 bp with each cell division. It is generally believed that when telomeres reach a critical length, a signal is activated to initiate the senescent program. This has given rise to the hypothesis that telomeres act as mitotic clocks to regulate lifespan. One proposes that cumulative oxidative stress, mainly reactive oxygen species generated from mitochondria, may mainly cause telomere shortening, accelerating aging. Here, the biological importance and mechanism of replicative senescence were briefly reviewed. Also it was summarized that how oxidative stress affects replicative senescence and telomere shortening.

• Geomechanics and Engineering
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• v.38 no.6
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• pp.621-631
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• 2024

In designing earthquake-resistant structures, we traditionally select dynamic loads based on the recurrence period of earthquakes, using individual seismic records or aligning them with the design spectrum. However, these records often represent isolated waveforms lacking continuity, underscoring the need for a deeper understanding of natural seismic phenomena. The Earth's crustal movement, both before and after a significant earthquake, can trigger a series of both minor and major seismic events. These minor earthquakes, which often occur in short time before or after the major seismic events, prompt a critical reassessment of their potential impact on structural design. In this study, we conducted a detailed tunnel response analysis to assess the impact of both single mainshock and multiple earthquake scenarios (including foreshock-mainshock and mainshock-aftershock sequences). Utilizing numerical analysis, we explored how multiple earthquakes affect tunnel deformation. Our findings reveal that sequential seismic events, even those of moderate magnitude, can exert considerable stress on tunnel lining, resulting in heightened bending stress and permanent displacement. This research highlights a significant insight: current seismic design methodologies, which predominantly focus on the largest seismic intensity, may fail to account for the cumulative impact of smaller, yet frequent, seismic events like foreshocks and aftershocks. Our results demonstrate that dynamic analyses considering only a single mainshock are likely to underestimate the potential damage (i.e., ovaling deformation, failure lining, permanent displacement etc.) when compared to analyses that incorporate multiple earthquake scenarios.

• Korean Journal of Environmental Biology
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• v.25 no.1
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• pp.27-33
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• 2007

Sediment microcosm experiments were conducted for 14 and 28 days using Zn spiked sediment to examine chronic toxicity (mortality) of Diporeia spp. as a function of density and time. Mean cumulative Diporeia mortality in 28 day sediment microcosms was 25% at $1,800\;{\mu}g\;g^{-1}$ total Zn in sediment. Although a certain fraction $(20{\sim}40%)$ of Diporeia was dead, its mortality was attributed by handling stress within 4 days and was not significantly encreased with increasing within the range of Zn concentrations examined in this study. These results suggest that Diporeia can tolerate Zn contaminated sediment and may be useful as a biomonitor for Zn contamination in freshwater environments.

• Coupled systems mechanics
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• v.2 no.1
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• pp.85-110
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• 2013

Generally, mass concrete structural behavior is governed by the strain components. However, relevant guidelines in dam engineering evaluate the structural behavior of concrete dams using stress-based criteria. In the present study, strain-based criteria are proposed for the first time in a professional manner and their applicability in seismic failure evaluation of an arch dam are investigated. Numerical model of the dam is provided using NSAD-DRI finite element code and the foundation is modeled to be massed using infinite elements at its far-end boundaries. The coupled dam-reservoir-foundation system is solved in Lagrangian-Eulerian domain using Newmark-${\beta}$ time integration method. Seismic performance of the dam is investigated using parameters such as the demand-capacity ratio, the cumulative inelastic duration and the extension of the overstressed/overstrained areas. Real crack profile of the dam based on the damage mechanics approach is compared with those obtained from stress-based and strain-based approaches. It is found that using stress-based criteria leads to conservative results for arch action while seismic safety evaluation using the proposed strain-based criteria leads to conservative cantilever action.