• Proceedings of the Korean Fiber Society Conference
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• 2003.10a
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• pp.41-42
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• 2003

Osteoblasts (MC3T3-E1) were cultured on polysaccharide type polyelectrolyte complex (PEC). The growth of the MC3T3-E1 on the PEC with carbxyl group (c-type) was slightly suppressed and exhibited aggregation morphology. On the other hand, cell growth on the PEC with sulfate group (s-type) was enhanced and the cell exhibited spreading form. Differentiation markers of osteoblast (ALPase activity, calcification, expression of osteocalsin) were enhanced and localized around cell aggregates on c-type PECs. These results suggest that PEC has the ability to control osteoblast proliferation and differentiation.

• Korean System Dynamics Review
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• v.5 no.2
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• pp.5-31
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• 2004

systems thinking is a methodology to explain structural mechanisms for resolving problems in highly complex and dynamic society. This article applies systems thinking to understand recent social and political changes in South Korea. This article identifies the weakers' virtuous circle that played central role in reinforcing soical climate to support the weakers and the oppressed group. Also this article adopts the concept of tipping points and triggers to explain how the political and social changes are produced and widely accepted in a few days. In conclusion we propose that systems thinking is promising in understand social and political changes.

• Korean Institute of Interior Design Journal
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• no.7
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• pp.87-96
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• 1996

In today's man's domestic environments, the development of furnishings in their various shapes and functions is as complex as human lives. Architecture, Interior, and Furniture, each one of these have the relationship closer and closer to the direct human environments. In this study, by choosing the theme of sitting , the transformation of man's behavioral models would be examined in sociological terms. By viewing the chair as an emblematic objects made for more than just sitting, the chair has revealed the relations of man with his environment since the history of furnishings began. Qualified architects and designers know that chairs are no longer the objects, but the primary subject of furnishings. Through this examination of the emblematic typologies of periodic chairs in the history of the Western culture, in terms of their relationships with politics , religions, monarchies, societies, and etc., the meaning of the designs could be find and which could be the resolutions for the future innovative design. These refound or recreated meanings in the history of design could create another typology for the future reality.

• Proceedings of the Korean Institute of Interior Design Conference
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• 2006.11a
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• pp.95-98
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• 2006

Movement from aging society to aged society and to ultra aged society is a fact that we have to accept as reality. It also means that we are given a common assignment of supporting the aged. Therefore, this study dealt with forms of space of the welfare facilities for the aged in Japan that are being suggested as a plan to solve the problem of supporting the aged. Japan who has similar Confucian culture like Korea experienced the aging of population 30 years earlier and enactment of law 20 years earlier than Korea. Therefore, Korean policies, systems and standards for welfare of the aged have been following Japanese welfare development model. This study analyzed the small-scale multifunctional welfare facilities for the aged in Japan before founding them in Korea to adapt the facilities that are compatible in domestic circumstance.

• Proceedings of the Korean Institute of Interior Design Conference
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• 2006.11a
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• pp.223-226
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• 2006

The purpose of this design plan is a method for opening the church to regional society to contribute to make up the community within regional society and to achieve the desirable common society of christianity like following. 1)For opening churchs to regional society, the church has to make up exterior spaces sufficiently. 2)The main chapel has to planned with mutipurpose for fiexibility and various functions of contemporary church. 3)The whole facilities have to be organized with a kind of the complex or multifunctional building which can accommodate activities of education, recreation and culture, therefore, content with the community's requirements. 4)The architectural form of the church has to planned with human scale, considering harmonization with regional environment. Modern church architecture needs a centralized plan, a variety of shapes such as square, round oval and polygon rather then a rectangular which is able to bring about a closer reationship between the priest and the congregation in the church.

• Journal of Microbiology and Biotechnology
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• v.11 no.2
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• pp.204-210
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• 2001

Paclitaxel can be produced in high yield and with a high degree of purify from plant cell cultures of Taxus chinensis. The complete purification method was systematically established and described. This method was an efficient procedure for the purification of paclitaxel from crude paclitaxel, consisting or reverse-phase chromatography, followed by a normal-phase chromatography. The two-stage HPLC purification scheme serves as an effective and economical approach for resolving paclitaxel from complex mixtures of taxoids, with high purify (>99%) and low impurities (<0.1%). The process is readily scalable to a pilot plant and eventually to a production environment where multikilogram quantities of material are expected to be produced. The process has been optimized to minimize solvent usage, complexity, and operating costs.

• Journal of the Korean Society of Systems Engineering
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• v.7 no.1
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• pp.43-51
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• 2011

SE generally defines approaching ways of conducting identification, verification and integration of an optimized product and process solution to meet customer's needs by leveraging organizational competency in engineering and management. To successfully develop a new product under mass production contract, it is important to efficiently carry out the program by ensuring that three major competencies are secured; core technology, system integration, and program management. For successful implementation of tasks in the three areas, systematic execution is called for, which requires identifying risk factors in advance. In particular, comprehensive risk management role and responsibility is required for program management. Success of a development program is determined by complex elements of human resources, organization culture, and overall competency of an organization in technology and program management, including capability of the program manager. In this paper, a risk management solution is suggested to lead a program to success with a more efficient way through actual risk management by the concept of SE around the above three areas.

• Architectural research
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• v.11 no.2
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• pp.35-42
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• 2009

Recently, intensive urban redevelopment concentrated on new towns has reduced the number of settled population, and weakened various functions such as commercial, culture, education and welfare in old towns, and made the stagnation and declination of the entire or some parts of old towns. Urban regeneration project means renewing cities' functions in terms of physical, environmental, social, cultural, industrial and economic aspects or revitalizing the existing functions through improvement project in the entire or part of a city, which is now drawing keen attention from the public. However, urban regeneration project is huge in scale, needs long construction period and various complex facilities, and also characterized by complicated relations with many stakeholders. Due to such characteristics, there are many risks in the project. Therefore, systematic risk management is absolutely necessary to efficiently manage various risk factors inherent in urban regeneration project. The purpose of this research proposes a basic model to establish risk management plan and work process in order to help project participants to perform risk management more systematically and rationally in the development phase of urban regeneration project.

• Microbiology and Biotechnology Letters
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• v.10 no.3
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• pp.223-226
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• 1982

The aim of the present study was to assess the oxygen transfer rate and oxygen uptake rate in antibiotic fermentation. As a model study, cultures of Streptomyces kanamyceticus in a complex medium were analyzed to evaluate the oxygen transfer and uptake rates using oxygen balance technique. Quantitative evidence for the effect of oxygen transfer rate on the volumetric antibiotic production was clearly demonstrated. The oxygen uptake rates and the specific oxygen requirements were significantly changed with culture time. Those phenomena were indicative of biological turnover in the antibiotic fermentation.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.11 no.4
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• pp.213-217
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• 1978

Henri-Michaelis-Menten model for predicting the behavior of culture of Brevibacterium flavum under carbon limiting condition has been evaluated on a chemostat growing in the presence of the phenol derivatives: guaiacol, o-vanillin and vanillin. It is found that Henri-Michaelis-Menten model could be applicable to the evaluation of the growth rate of cells in the phenol derivatives. The marked enhancing abilities of the cells treated by the phenol derivatives during fermentation were ascribed to the formation of charge-transfer complex between the phenol-derivatives and oxygen which supplies oxygen effectively to the fermentation system.