• Journal of Sericultural and Entomological Science
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• v.50 no.2
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• pp.166-170
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• 2012

Most of Cudriania tricuspidata Bureau saplings in Korea have been produced by crown division. But the production of Cudriania tricuspidata B. saplings by this method is very low in efficiency and in uniformity. Therefore, to develop Cudriania tricuspidata B. saplings production system by cutting method which is suitable for mass production, several conditions on rooting and growth of cuttings were investigated. The rooting ability of cuttings varied according to temperature on the bed, length, thickness of the hard wood cutting and rooting agent application. Of different concentration of rooting agent, the 5,000 ppm of 1-naphthalenacetic acid(NAA) and Indole butyric acid(IBA) were found to be the highest in rooting of hardwood cuttings; other concentration were in order as follows; 2,500, 1,000 and 10,000 ppm in concentration of rooting agents. The shading ratio of polyethylene film showed the highest rooting ratio of the softwood cuttings at 55%.

• Herbal Formula Science
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• v.27 no.3
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• pp.223-236
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• 2019

Dengropanax morfiferus (D), Broussonitia kazinoki (B), and Cudriania tricuspidata (E), a widely cultivated species in South Korea, has been used as traditional medicine to treat numerous diseases. In this study, we evaluated the antidiabetic effects in a various signaling mechanisms using mixed extract and major component contents were analyzed by HPLC in the combined extracts from Dengropanax morfiferus, Broussonitia kazinoki, and Cudriania tricuspidata (DBCE). DBCE inhibited ${\alpha}$-glucosidase and ${\alpha}$-amylase activation and showed potent antioxidant effects, which are evaluated using DPPH, ABTS, and SOD assay. Cytokines, which are released by inflammatory cells in pancreatic islets, are involved in the pathogenesis of type 1 diabetes mellitus. DBCE showed the protective effects in RINm5F cells against cytokines-induced damage by suppressing inducible nitric oxide (NO) synthase and COX-2 expression and NO production. Insulin resistance is the primary characteristic of type 2 diabetes. Therefore, the regulatory effect of DBCE on glucose uptake and production are investigated in insulin-responsive human HepG2 cells. DBCE stimulated glucose uptake, prevented Glut2 and phosphor-IRS1 downregulation induced by high glucose (HG, 30 mM). Moreover, DBCE pretreatment diminished glucose levels, PEPCK and G6Pase overexpression provoked by HG. These findings suggest that DBCE might be used for diabetes treatment through alpha-glucosidase or alpha-amylase activity regulation, pancreatic beta cell protection, hepatic glucose sensitivity improvement. Cytokines, which are released by inflammatory cells' infiltrations around the pancreatic islets, are involved in the pathogenesis of type 1 diabetes mellitus.