• 제목/요약/키워드: Crude drug

검색결과 377건 처리시간 0.031초

백두옹의 생약학적 연구 (Pharmacognostical Studies on the 'BaegDuOng')

  • 배지영;전은진;박종희
    • 생약학회지
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    • 제42권1호
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    • pp.6-8
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    • 2011
  • 'BaegDuOng(白頭翁)' is one of the Chinese crude drugs used mainly as a pruritus, arthritis, cough and abdominal pain. The botanical origin of the crude drug has never been studied pharmacognostically. To clarify the botanical origin of 'BaegDuOng', the morphological and anatomical characteristics of Pulsatilla species growing in Korea, i.e. Pulsatilla koreana Nakai and P. cernua (Thunb.) Spreng. were studied. As a result, BaegDuOng from Korea was proved to be the root of Pulsatilla koreana.

해동계명환의 현미감정 연구 (Microscopic Identification of the Chinese Patent Medicine 'Hae Dong Gye Meong Hwan')

  • 박상일;황명석;심효영;박종희
    • 생약학회지
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    • 제29권3호
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    • pp.159-162
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    • 1998
  • 'Hae Dong Gye Meong Hwan' is a Chinese patent medicine, which is used as a cough remedy or an expectorant, for asthma, bronchitis, and so on in Korea. This powdery medicine consist of 14 kinds of crude drugs. For the identification of individual ingredients in the preparation, microscopic method may advantageously be used as it requires only a small amount of specimens. In this paper, the effectiveness of this method is exemplified by the identification of the ingredients.

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황백의 생약학적 연구 (Pharmacognostical Studies on the Whang Baig)

  • 박종희;오종영;배지영
    • 생약학회지
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    • 제40권2호
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    • pp.99-102
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    • 2009
  • 'Whang Baig(黃柏)' is one of the crude drugs used mainly as a removing dampness, purging fire, detoxicating, and cleaning away heat of deficiency type. The botanical origin of the crude drug has never been studied pharmacognostically in Korea. To clarify the botanical origin of Whang Baig, the anatomical characteristics of Phellodendron amurense Rupr., Phellodendron insulare Nakai and Phellodendron molle Nakai were studied. As a result, it was clarified that Whang Baig from Korea was the bark of Phellodendron amurense and Phellodendron molle.

일문전(Stephania delavayi Diels.) 메탄올, 부탄올, 에틸아세테이트 분획물의 항산화 및 세포증식억제 효과 (Antioxidative Effects and Anti-proliferative Effects of MeOH, BuOH and Ethyl Acetate Fractionated from Stephania delavayi Diels)

  • 이용순;김경희;서홍덕;박대훈;최연식;황혜림;이민재;최종진;권명상;육홍선
    • 한국식품영양과학회지
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    • 제38권3호
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    • pp.297-301
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    • 2009
  • 본 연구에서는 중국에서 급성 위장염에 대한 약제로 사용되어 오던 일문전의 메탄올 추출물을 이용하여 물, 에틸 아세테이트, 부탄올 층으로 분획한 뒤 항산화 활성과 항암활성을 측정하였다. DPPH 라디칼 소거능은 $1,000{\mu}g/mL$ 농도에서 부탄올(75.23%)> 메탄올(68.11%)> 에틸아세테이트 (63.58%)> 물(50.13%) 순으로 나타났으며 환원력의 경우 용매 분획물의 농도가 증가함에 따라 환원력이 증가하는 경향을 나타내었다. DPPH 라디칼 소거능 및 환원력 모두 부탄올 분획층에서 좋은 활성을 나타내었다. 항암활성 측정결과 메탄올 추출물과 부탄올 분획물, 에틸 아세테이트 분획물에서 MDA-MB-231 cell과 MCF-7 cell에 대한 세포증식억제효과를 나타내었다. 이상의 결과에서 일문전의 용매 분획물은 항암 후보물질로의 가능성이 있을 것으로 사료된다.

천연산 및 양식산 뱀장어, 복어, 가물치의 맛 성분에 대한 연구 (Comparison of The Taste Compounds of Wild and Cultured Eel, Puffer and Snake head)

  • 김희연;신재욱;심규창;박희옥;김현숙;김상무;조재선;장영미
    • 한국식품과학회지
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    • 제32권5호
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    • pp.1058-1067
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    • 2000
  • In this study, eel, puffer and snake head fish, which are widely taken and highly valued for processing into baked fish, soup or fish juice were studied by classifying them into wild fish and cultured fish, and evaluated in terms of taste. The samples were gathered in the area including Kimhae, Samchonpo and Haman in Kyungsangnam-do, Kangsu-Gu in Pusan and Bukcheju-Gun in Cheju-do. Proximate compositions, the content of nucleotides and their related compounds, total and free amino acids, organic acids and fatty acids of the fishes were analysed. Generally, as for the compositions, wild fish had a higher crude fat content and a lower moisture content as compared with cultured fish, while there was no great difference between them in terms of crude protein and ash contents. Nucleotides and their related compounds including ATP, ADP, AMP, IMP, HxR, Hx were detected, and the amounts of which were nearly the same with respect to the growth conditions. IMP content was high in all of the samples, while ATP content was extremely low. Total 17 amino acids were detected from the samples, and most of the samples had high contents of glutamic acid, aspartic acid, lysine, leucine, glycine, alanine and arginine, and low contents of cystein, isoleucine and methionine. As for the other amino acids, generally same level of contents were detected for each samples. In cases of eel and snake head fish, the wild fish had higher total amino acid contents in comparison with cultured fish. And the result to the contrary was obtained for the case of puffer. Sample fishes had nearly the same compose distribution of free amino acid though the contents of which were a little different according to the samples. Each sample had high contents of taurine, hydroxyproline, glutamic acid, glycine, cystathionine, ${\beta}-aminoisobutyric$ acid and lysine. Total organic acid contents of cultured fish was higher than that of wild fish. All fishes commonly had high contents of lactic acid, iso-valeric acid, oxalic acid and fumaric acid. High levels of $C_{16:0},\;C_{16:1},\;C_{18:1(cis)},\;C_{18:3},\;and\;C_{22:6}$ were shown in all of the samples and ${\omega}-3$ polyunsaturated fatty acid content of cultured fish was higher than that of wild fish, and as for the essential fatty acid, wild fish has higher content in comparison with cultured fish.

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단삼(Salvia miltiorrhiza Bunge)으로 부터 Tanshinone IIA의 분리 및 함량분석 (Isolation and Quantitative Determination of Tanshinone IIA from the Rhizomes of Salvia miltiorrhiza Bunge)

  • 박미정;이승호;박정일;강신정;장승엽;이경순;손건호
    • 생약학회지
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    • 제30권2호
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    • pp.158-162
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    • 1999
  • The rhizomes of Salvia miltiorrhiza Bunge(Labiatae) has been used in Chinese traditional medicine for the treatment of coronary heart diseases and myocardial infarction. As a part of a research for standardization of crude oriental drugs, we have determined the content of tanshinone IIA in Salvia miltiorrhiza purchased from various regions of Korea. The HPLC method by which quantitative analysis was conducted, showed reproducible results and chromatographic isolation of tanshinone IIA was accomplished successively.

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정신약리학(精神藥理學)의 연구방법(硏究方法)의 제문제(諸問題) (Methodological Issues in Psychopharmacology)

  • 장현갑
    • 생약학회지
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    • 제8권4호
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    • pp.139-148
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    • 1977
  • It is the purpose of this article to present a brief and systematical behavioral methods in recent developed behavioral pharmacology. Specifically, the present review has been organized around three major topics reflecting both current research emphasis in behavioral pharmacology and methodological applications to the study of psychopharmacological actions of crude drug or herb medicine. The first major topic focuses upon the appropriate experimental design especially in the study of psychopharmacology. A large number of factors should be controlled to have a bearing on design of studies reflecting to psychological effects of drugs. The second section presents several recent methodological developments in behavioral pharmacology involving Turner's screening methods and several types of conditioning techniques. The last section calls specific attention to the observation of behavioral development processes in relation to the activity of pharmacological agents and emphasizes critical period of drug treatment.

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An Identity Based Pharmacognostical Profile of folium Annona squamosa

  • Kumar, C. Dinesh;Rajendran, K.;Lobo, Richard;Shirwaikar, Annie
    • Natural Product Sciences
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    • 제11권4호
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    • pp.213-219
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    • 2005
  • The leaves of Annona squamosa Linn. (Annonaceae), commonly called as custard apple, are popularly used for the treatment of diabetes by various tribes in India. The leaves are also used for their powerful insecticidal activity, especially for destroying lice. This paper present a detailed pharmacognostical study of the crude drug folium Annona squamosa. The samples were studied using procedures of light, confocal microscopy, WHO recommended physico-chemical determinations and authentic phytochemical procedures. The physicochemical, morphological and histological parameters presented in this paper may be proposed as parameters to establish the authenticity of Annona squamosa leaf and may possibly help to differentiate the drug from its adulterants.

민간약 "진해초"의 생약학적 연구 (Pharmacognostical Studies on the Korean Folk Medicine 'Jin Hae Cho')

  • 박종희;도진경
    • 생약학회지
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    • 제25권2호
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    • pp.178-187
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    • 1994
  • Korean folk medicine 'Jin Hae Cho' has been used as a remedy for neuralgia and an invigorating drug after a childbirth in Korea. The botanical origin of the crude drug has been no pharmacognostical confirmation on it. To clarify the botanical origin of 'Jin Hae Cho', studied on the morphological and anatomical characteristics of the roots of Potentilla species growing wild in Korea i.e. Potentilla chinensis Ser., P. cryptotaeniae Maxim., P. dickinsii Fr. et Sav., P. discolor Bunge, P. fragarioides L. var. major Maxim., P. freyniana Bornm., P. kleiniana Wight et Arnott, P. paradoxa Nutt., P. yokusaiana Makino and 'Jin Hae Cho' from Korea on Korean market. As a result, it was made clear that 'Jin Hae Cho' from Korea was derived from the roots of Potentilla chinensis Ser. and Potentilla discolor Bunge.

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Antinociceptive and antidiarrhoeal activities of Sonneratia caseolaris

  • Ahmed, F;Baksi, B;Sadhu, SK;Shahid, IZ
    • Advances in Traditional Medicine
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    • 제7권3호
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    • pp.274-279
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    • 2007
  • The crude ethanol extract of leaves of Sonneratia caseolaris Linn. (Sonneratiaceae) was screened for its antinociceptive and antidiarrhoeal activities. The extract produced significant writhing inhibition in acetic acid induced writhing in mice at dose of 250 and 500 mg/kg body weight (P<0.01) comparable to the standard drug diclofenac sodium at the dose of 25 mg/kg of body weight. When tested for its antidiarrhoeal effects on castor oil induced diarrhea in mice, it increased mean latent period and decreased the frequency of defecation significantly at the dose of 500 mg/kg body weight (P < 0.05) comparable to the standard drug loperamide at the dose of 50 mg/kg of body weight. The overall results tend to suggest the antinociceptive and antidiarrhoeal activities of the extract.