• Title/Summary/Keyword: Cross-sectional factor

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Pretreatment Serum Albumin Level is an Independent Prognostic Factor in Patients with Stage IIIB Non-Small Cell Lung Cancer: A Study of the Turkish Descriptive Oncological Researches Group

  • Tanriverdi, Ozgur;Avci, Nilufer;Oktay, Esin;Kalemci, Serdar;Pilanci, Kezban Nur;Cokmert, Suna;Menekse, Serkan;Kocar, Muharrem;Sen, Cenk Ahmet;Akman, Tulay;Ordu, Cetin;Goksel, Gamze;Meydan, Nezih;Barutca, Sabri
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.5971-5976
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    • 2015
  • Background: Several prognostic factors have been studied in NSCLC, although it is unknown which is most useful. In this study, we aimed to investigate whether pre-treatment serum albumin level has prognostic value in patients with Stage IIIB NSCLC. Materials and Methods: This cross-sectional study included a total of 204 patients with Stage IIIB NSCLC who met the inclusion criteria. Pre-treatment serum albumin levels and demographic, clinical, and histological characteristics, as well as laboratory variables were recorded. A cut-off value was defined for serum albumin level and the patients were stratified into four groups on thios basis. Results: The majority of the patients was males and smokers, with a history of weight loss, and squamous histological type of lung cancer. The mean serum albumin level was $3.2{\pm}1.7g/dL$ (range, 2.11-4.36 g/dL). A cut-off value 3.11 g/dL was set and among the patients with a lower level, 68% had adenocarcinoma and 82% were smokers. The patients with low serum albumin levels had a lower response rate to e first-line chemotherapy with a shorter progression-free survival and overall survival. Multivariate analysis showed that low serum albumin level was an independent poor prognostic factor for NSCLC. Conclusions: This study results suggest that low serum albumin level is an independent poor prognostic factor in patients with Stage IIIB NSCLC, associated with reduction in the response rate to first-line therapy and survival rates.

An Evaluation Study on the Cardiovascular Risk Factors in a Rural Adult Population (농촌지역 주민의 심혈관 질환 위험요인 평가)

  • Na, Baek-Ju;Park, Kyung-Soo;Lim, Jung-Su;Sun, Byeong-Hwan;Nam, He-Sung;Sohn, Seok-Joon
    • Journal of agricultural medicine and community health
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    • v.23 no.2
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    • pp.193-204
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    • 1998
  • Cardiovascular diseases are the leading cause of death and disability in Korea. Their risk factors can be classified as either modifiable or nonmodifiable and among modifiable factors are high bood pressure, elevated blood cholesterol, obesity and cigarette smoking. The purpose of this study was to evaluate the risk factors for the cardiovascular diseases in a rural community and to get basic data for the development of a community-based rick reduction intervention program. Evaluation involved population-based, cross-sectional samples of adult residents in a rurual community. We measured blood pressure, body fat percent by bioelectric impedance fatness analyzer and serum cholesterol and interviewed adult residents over 20-year-old age. Blood pressure was checked twice and hypertension was classified by the sixth report of the Joint National Committee on Detection. Evaluation, and Treatment of High Blood Pressure. The Cutpoints for high blood cholesterol was used National Cholesterol Treatment Guidelines and those for obesity was 25% in male. 30% in female. The results were as follows: 1. Prevalence of definitive hypertension was 59.7% in males and 54.4% in female. 2. Prevalence of hypercholesterolemia was 14.3% in male and 18.2% in female. 3. Prevalence of obese was 10.7% in male and 41.1% in female. 4. Among definitive hypertension, hypercholesterolemia, and obesity 52.1% possessed one risk factor, 12.6% two risk factors and 2.5% three risk factors in males. In females 41.4% possessed one risk factor and 27.6%. 5.7% respectively. 5. The smoking rate was 65.8% in males and 5.2% in females. Our results are used effectively for the community-based intervention towards cardiovascukr diseases risk reduction. However, because of limitations in our study design, further datas are needed including other risk factors and in-person clinical datas.

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A Study on Relationship among Recognized by Tourism Gentrification and Urban Image (지역거주민의 지각하는 관광 젠트리피케이션과 도시이미지간의 관계 연구)

  • Yang, Sung-Soo;Joa, Bong-Doo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.10
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    • pp.384-394
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    • 2019
  • The purpose of this study is to investigate the relationships between physical factors, economic factors, and cultural factors of tourism gentrification (TG) in urban areas. Based on the results of an empirical analysis, we provide the basic theory and practical implications of the relationship between tourism phenomena and city image. This study used a questionnaire for residents of the Jeju area. From September 1, 2018, to October 3, 2018, the survey was conducted in Nuemori Street, Yeongdong Street, Gucheong Eup, and Moon Town. Thus, we use 479 samples for analysis out of 500 samples obtained. This study produced two important results. First, the physical, economic, and cultural factors of tourism gentrification have significant effects on cognitive image and emotional image. Second, economic factors have statistical significance in cognitive image and emotional image. These results and implications can be useful for practical implications of the theoretical implications of tourism gentrification and regional specialization promotion policies. In addition, from the economic point of view, what should be considered is that development-centered area development can have a negative impact on urban image. Despite these research results, there are limitations in the research, such as cross-sectional studies and short-term studies, and we look forward to a longitudinal study in the future from a long-term perspective.

Numerical Analysis for Dynamic Characteristics of Next-Generation High-Speed Railway Bridge (차세대 고속철 통과 교량의 동적특성에 대한 수치해석)

  • Oh, Soon-Taek;Lee, Dong-Jun;Yi, Seong-Tae;Jeong, Byeong-Jun
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.26 no.2
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    • pp.9-17
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    • 2022
  • To take into account of the increasing speed of next generation high-speed trains, a new design code for the traffic safety of railway bridges is required. To solve dynamic responses of the bridge, this research offers a numerical analyses of PSC (Pre-stressed Concrete) box girder bridge, which is most representative of all the bridges on Gyungbu high-speed train line. This model takes into account of the inertial mass forces by the 38-degree-of-freedom and interaction forces as well as track irregularities. Our numerical analyses analyze the maximum vertical deflection and DAF (Dynamic Amplification Factor) between simple span and two-span continuous bridges to show the dynamic stability of the bridge. The third-order polynomial regression equations we use predict the maximum vertical deflections depending on varying running speeds of the train. We also compare the vertical deflections at several cross-sectional positions to check the influence of running speeds and the maximum irregularity at a longitudinal level. Moreover, our model analyzes the influence lines of vertical deflection accelerations of the bridge to evaluate traffic safety.

Preparation and Characterization of Organic Solvent Reverse Osmosis (OSRO) Membranes Using Polyketone (PK) Supports (폴리케톤(PK) 지지체를 이용한 유기용매 역삼투(OSRO) 분리막의 제조 및 특성 평가)

  • Seoungwoo Kim;Seunghee Hong;Hee Min Park;Yong Taek Lee
    • Membrane Journal
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    • v.34 no.4
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    • pp.205-215
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    • 2024
  • The purpose of this paper was to preparation of organic solvent reverse osmosis (OSRO) membrane using a polyketone (PK) support. The PK support was prepared by non-solvent induced phase separation (NIPS) method, and a polyamide layer was interfacially polymerized on the PK support to fabricate OSRO membrane in the form of thin-film composite (TFC). After that, the surface and cross-sectional morphology of the OSRO membrane were analyzed, and the surface chemical structure of the membrane was analyzed. The water permeance and salt rejection of the OSRO membrane were about 1.28 LMH/bar and 99.0% respectively. The polyamide layer of the OSRO membrane was very stable during 1 day of organic solvent immersion, and the single organic solvent permeance trend was consistent with the organic solvent nanofiltration (OSN) membrane permeance model. The MWCO of the OSRO membrane is 240 g/mol in MeOH. The permeance and separation factor of the OSRO membrane for MeOH-toluene mixture were 200% and 60% higher than those of the commercial OSN membranes respectively.

Cross-Sectional Item Response Analysis of Geocognition Assessment for the Development of Plate Tectonics Learning Progressions: Rasch Model (판구조론의 학습발달과정 개발을 위한 지구적 인지과정 평가의 횡단적 문항 반응 분석: Rasch 모델)

  • Maeng, Seungho;Lee, Kiyoung
    • Journal of The Korean Association For Science Education
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    • v.35 no.1
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    • pp.37-52
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    • 2015
  • In this study, assessment items to examine geocognition on plate tectonics were developed and applied to middle and high school students and college students. Conceptual constructs on plate tectonics are Earth interior structure, specific geomorphology, and geologic phenomena at each plate boundary. Construct for geocognition included temporal reasoning, spatial reasoning, retrospective reasoning, and system thinking. Pictorial data in each item were all obtained from GeoMapApp. Students' responses to the items were analyzed and measured cross-sectionally by Rasch model, which distinguishes persons' ability levels based on their scores for all items and compared them with item difficulty. By Rasch model analysis, Wright maps for middle and high school students and college students were obtained and compared with each other. Differential Item Functioning analysis was also implemented to compare students' item responses across school grades. The results showed: 1) Geocognition on plate tectonics was an assessable construct for middle and high school students in current science curriculum, 2) The most distinguished geocognition factor was spatial reasoning based on cross sectional analysis across school grades, 3) Geocognition on plate tectonics could be developed towards more sophisticated level through scaffolding of relevant instruction and earth science content knowledge, and 4) Geocognition was not a general reasoning separated from a task content but a content-specific reasoning related to the content of an assessment item. We proposed several suggestions for learning progressions for plate tectonics and national curriculum development based on the results of the study.

A Study on Oil Price Risk Affecting the Korean Stock Market (한국주식시장에 파급되는 국제유가의 위험에 관한 연구)

  • Seo, Ji-Yong
    • The Korean Journal of Financial Management
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    • v.24 no.4
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    • pp.75-106
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    • 2007
  • In this study, it is analyzed whether oil price plays a major role in the pricing return on Koran stock market and examined why the covariance risk between oil and return on stock is different in each industry. Firstly, this study explores whether the expected rate of return on stock is pricing due to global oil price factors as a function of risk premium by using a two-factor APT. Also, it is examined whether spill-over effects of oil price volatility affect the beta risk to oil price. Considering the asymmetry of oil price volatility, we use the GJR model. As a result, it shows that oil price is an independent pricing factor and oil price volatility transmits to stock return in only electricity and electrical equipment. Secondly, the two step-analyzing process is introduced to find why the covariance between oil price factor and stock return is different in each industry. The first step is to study whether beta risk exists in each industry by using two proxy variables like size and liquidity as control variables. The second step is to grasp the systematic relationship between the difference of liquidity and size and beta to oil price factor by using the panel-data model which can be analyzed efficiently using the cross-sectional data formed with time series. Through the analysis, we can argue that oil price factor is an independent pricing factor in only electricity and electrical equipment having the greatest market capitalization, and know that beta risk to oil price factor is a proxy of size in the other industries. According to the result of panel-data model, it is argued that the beta to oil price factor augments when market capitalization increases and this fact supports the first assertion. In conclusion, the expected rate of return of electricity and electrical equipment works as a function of risk premium to market portfolio and oil price, and the reason to make beta risk power differentiated in each industry attributes to the size.

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Availability of Diagnosis of Yin-deficiency in Elderly People with Xerostomia and Factors Influencing Subjective Oral Dryness: A Prospective Cross-sectional Study (노인 구강건조증에 대한 음허 진단의 유용성 및 주관적 구강건조감의 영향요인 : 전향적 단면 조사 연구)

  • Kim, Juyeon;Kim, Jinsung;Park, Jaewoo;Ryu, Bongha
    • The Journal of Korean Medicine
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    • v.34 no.3
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    • pp.13-24
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    • 2013
  • Objectives: The aims of this study were to investigate the availability of diagnosis of Yin-deficiency in the elderly with xerostomia and factors influencing subjective oral dryness. Methods: We surveyed 50 patients recruited by the clinical trial, 'Efficacy of Yukmijihwang-tang on Xerostomia in the Elderly: A Randomized, Double-blind, Placebo-controlled, Two-center Trial'. The subjects were assessed on their subjective oral dryness using the Dry Mouth Symptom Questionnaire (DMSQ). Their salivary functions were measured by Unstimulated Salivary Flow Rate (USFR) measurements. In addition, the subjects were evaluated on their Qi-stagnation and Yin-deficiency conditions using the Qi-stagnation questionnaire and Yin-deficiency questionnaire. Results: There were statistically significant correlations between three variables (USFR, DMSQ score and Qi-stagnation score) and Yin-deficiency score. In the multiple regression analysis, the regression model was statistically significant (F = 10.273, p < .001). The factor most strongly influencing the subjective oral dryness was USFR (${\beta}$ = -0.386). Yin-deficiency had the next strongest impact on the subjective oral dryness (${\beta}$ = 0.371). Qi-stagnation affected the subjective oral dryness weakly (${\beta}$ = 0.075). In the simple regression analysis, Yin-deficiency had a statistically significant effect on each of six subscales of DMSQ (p < .01). Among the six subscales, DMSQ-1 ('Oral dryness at night or on awakening') was the most strongly influenced by Yin-deficiency. Conclusions: The results of this study show that the diagnosis of Yin-deficiency in the elderly with xerostomia was available and Yin-deficiency was an important factor influencing the subjective oral dryness. Therefore, the consideration of Yin-deficiency is significant for diagnosis and treatment in the elderly with xerostomia.

Convergence factor Influencing Job Satisfaction of Radiographer (방사선사의 직무만족도에 영향을 미치는 융복합요인)

  • Lee, Mi-Hwa
    • Journal of Digital Convergence
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    • v.13 no.8
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    • pp.357-368
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    • 2015
  • This cross-sectional study was performed to offer radiographer who registered to the Korean Association of Radiographers as a basic material promote job satisfaction and lower job stress. A total of 213 radiographer were surveyed using a self-administered questionnaire. The 105 questionnaires consist of general characteristics, job characteristics, job stress, and job satisfaction. The job satisfaction was categorized into 3 sub-scales; psychological variables, environmental variables, and structural variables. The job stress insufficient job control, interpersonal conflict, job insecurity, organizational system, lack of reward, and occupational climate. Job satisfaction in psychological variables of radiographer was higher in the radiographers who have a high level of education, work in seoul,have a high sense of mission, don't have job leaving attitude, have a lower job insecurity. Job satisfaction in environmental variables of radiographer was higher in the radiographers who get lower salary. Job satisfaction in structural variables of radiographer was higher in the radiographers who have a high sense of mission, don't have job leaving attitude, have a lower organizational system, lack of reward, and occupational climate. Job satisfaction of radiographer was higher in th radiographers who don't have job leaving attitude, have a high sense of mission, have a lower lack of reward, and occupational climate.

Decisional balance corresponding to the Stage of Change of Exercise in Elderly (노인운동의 변화단계에 따른 의사결정 균형에 대한 연구)

  • Kim, So In;Chun, Young Ja;Lee, Pyoung Sook;Kim, Soon Yong;Lee, Sook Ja;Park, Eun Sook;Chang, Sung Ok
    • Korean Journal of Adult Nursing
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    • v.12 no.1
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    • pp.40-51
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    • 2000
  • Purpose : This study was carried out to identify the factor of decisional balance for exercise. This was composed of a set of variables at the level of decision making when the elderly decide to do exercise. It was used to classify and identify the characteristics of the stages of change for exercise to which the elderly belong, and was used to identify the variables of decisional balance which influence the stage of change for exercise in the elderly. Methods : Convenient samples of 198 subjects over age 60 in Seoul( mean age=70) were selected from community living, mentally competant older adults and the data was collected from April 1, 1999 to May 31, 1999. The research instrument was the Decisional Balance Measure for Exercise(Marcus & Owen., 1992), Stage of Change Measure(Marcus et al,1992). The data was analyzed by SAS Program. Results: 1. According to stage of change measure, without missing data,191 subjects were distributed in each stage of change for exercise : 50 subjects(26.1%), 7 subjects (3.6%), 52 subjects(27.2%), 4 subjects(2%), and 78(40.8%) belonged to the precontemplation stage, contemplation stage, preparation stage, action stage and maintenace stage. 2. Factor analysis identified 3 factors of decisional balance as appropriate factors for exercise of the elderly and named by researchers; 1)'Perceived Physical-psychological benefit', 2)'Perceived Physical-psychological burden', and 3)'Perceived time burden'. 3. The analysis of variance showed that the two components Perceived Physical - psychological benefit(F=45.95, P=.0001), and Perceived Physical-psychological burden (F=26.52, P=.0001) were significantly associated with stage of change. 4. Through the discriminant analysis, it was found that both 'Self Perceived Physical - Psychological benefit' and 'Perceived Physical-Psychological burden' were the influential variables in discriminating the three stages of change(pre-contemplation, preparation, and maintenance). Conclusion : Results are consistent with the application of the Transtheoretical model, which has been used to understand how people change health behaviors. Even though this study is a cross-sectional, not a longitudinal study, the findings of this study give useful information for exercise intervention about especially the factors relating to decision making for exercise of the elderly in the different stages of change of exercise.

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