• Asian Pacific Journal of Cancer Prevention
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• 제13권1호
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• pp.97-101
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• 2012

Objective: With the background of aging population in China and advances in clinical medicine, the amount of operations on old patients increases correspondingly, which imposes increasing challenges to critical care medicine and geriatrics. The study was designed to describe information on the length of ICU stay from a single institution experience of old critically ill gastric cancer patients after surgery and the framework of incorporating data-mining techniques into the prediction. Methods: A retrospective design was adopted to collect the consecutive data about patients aged 60 or over with a gastric cancer diagnosis after surgery in an adult intensive care unit in a medical university hospital in Shenyang, China, from January 2010 to March 2011. Characteristics of patients and the length their ICU stay were gathered for analysis by univariate and multivariate Cox regression to examine the relationship with potential candidate factors. A regression tree was constructed to predict the length of ICU stay and explore the important indicators. Results: Multivariate Cox analysis found that shock and nutrition support need were statistically significant risk factors for prolonged length of ICU stay. Altogether, eight variables entered the regression model, including age, APACHE II score, SOFA score, shock, respiratory system dysfunction, circulation system dysfunction, diabetes and nutrition support need. The regression tree indicated comorbidity of two or more kinds of shock as the most important factor for prolonged length of ICU stay in the studied sample. Conclusions: Comorbidity of two or more kinds of shock is the most important factor of length of ICU stay in the studied sample. Since there are differences of ICU patient characteristics between wards and hospitals, consideration of the data-mining technique should be given by the intensivists as a length of ICU stay prediction tool.

• Journal of Clinical Nutrition
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• 제10권2호
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• pp.51-55
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• 2018

Purpose: This study was conducted to assess how extreme obesity affects 30-day mortality in this patient group. Methods: A total of 802 patients who underwent emergency gastrointestinal surgery from January 2007 to December 2017 were retrospectively reviewed. Patients were divided into three groups according to their body mass index (BMI): group 1, normal weight (BMI: $18.5{\sim}22.9kg/m^2$); group 2, overweight (BMI: $23.0{\sim}29.9kg/m^2$ ); and group 3, obesity ($BMI{\geq}30kg/m^2$). Patients with a BMI under 18.5 were excluded from the analysis. Chi-squared test, Fisher's exact test, Kaplan-Meier survival analysis, and the log-rank test were used to assess and compare 30-day mortality rates between groups. Results: The mortality rates of group 1, group 2, and group 3 were 11.3%, 9.0%, and 26.9%, respectively (P<0.017). The mortality rate did not differ significantly between group 1 and 2 (11.3% vs. 9.0%; P=0.341), but group 1 and 2 showed better survival rates than group 3 (11.3% vs. 26.9%; P=0.028, 9.0% vs. 26.9%; P=0.011). Kaplan-Meier survival analysis revealed that group 3 had higher mortality than the other two groups (P=0.001). Conclusion: Obesity ($BMI{\geq}30kg/m^2$) was one of the risk factors influencing critically ill patients who underwent emergency surgery.

• 대한치과보철학회지
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• 제58권4호
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• pp.378-384
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• 2020

잘 맞지 않는 의치를 장기간 사용하여 불안정한 하악운동을 가진 환자에게서 성공적인 새 의치를 제작하는 것은 도전적이다. 이러한 증례에서 새 의치를 제작하기 전에 정확한 중심위를 채득하는 것은 매우 중요하다. 본 증례에서 하악의 운동을 안정화 시키고, 중심위를 채득하기 위해 flat occlusal table을 가진 치료의치를 이용하였다. 치료의치를 통해 얻어진 환자의 악간관계와 수직고경을 최종의치에 최대한 반영하기 위해 치료의치를 디지털 복제하였고, 복제된 치료의치 이용하여 인상과 악간관계 채득하였다. 이를 통해 심미적, 기능적으로 만족할 만한 결과를 얻었기에 보고하는 바이다.

• Journal of Acupuncture Research
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• 제17권3호
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• pp.233-249
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• 2000

Objectives : Gimun-chimbub(Jimen-zhenfa) is the method of needling which is based on Gimun-hak (Jimen-xue), and it is the most excellent method of needling than any other methods. In spite of the superiority of Gimun-chimbub(Jimen-zhenfa), there are few documents which explain it in details. The purpose of this study is to make clear principle of Gimun(Jimen) & apptication of Gimun-chimbub(Jimen-zhenfa) so many clinicians can make good use of it. Methods : Through investigation of many documents concerning Gimun(Jimen), Gimun-chimbub(Jimen-zhenfa) and Bosa(buxie), the author first explained principle of Gimun(Jimen) and then made clear how to apply it in needling and how to perform Bosa(buxie). Conclusions : 1. Gimun-hak(Jimen-xue) is constituted combinations of infinite change of Chen-Gy-In Samje(Tianrendi Sancai) and Hado lakse(Hetu Luoshu). Gimun-hak(Jimen-xue), is the study which shows us the change of space time e- ntangling at once, and it is applied to troublous times and critical situations. Gimun-chimbub(Jimen-zhenfa) combines of the method of needling with the time when Chen(Tian) opens and closes. So according to each cases, doctor must consider the adequate time. For example, in case of acute disease, the first day when the patient got ill is ta - ken. In case of chronic disease, the day when the patient came to see a doctor is taken. In Gimun-chimbub(Jimen-zhenfa), first it uses Jik-Sa-Mun(zhishimen) which can ac - cept Chen-Gi(tianqi). When needling, doctor must find the accurate acu-points and perform Bosa(buxie). Finally it uses Saeng-Mun(shengmen) which stirs up the vit - ality. Using Saeng-Mun(shengmen) decreases the rate of relapse of diseases.

• Journal of Korean Neurosurgical Society
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• 제67권4호
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• pp.451-457
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• 2024

Objective : Exploring protein requirements for critically ill patients has become prominent. On the other hand, considering the significant impact of coma therapy and targeted temperature management (TTM) on the brain as well as systemic metabolisms, protein requirements may plausibly be changed by treatment application. However, there is currently no research on protein requirements following the application of these treatments. Therefore, the aim of this study is to elucidate changes in patients' protein requirements during the application of TTM and coma therapy. Methods : This study is a retrospective analysis of prospectively collected data from March 2019 to May 2022. Among the patients admitted to the intensive care unit, those receiving coma therapy and TTM were included. The patient's treatment period was divided into two phases (phase 1, application and maintenance of coma therapy and TTM; phase 2, tapering and cessation of treatment). In assessing protein requirements, the urine urea nitrogen (UUN) method was employed to estimate the nitrogen balance, offering insight into protein utilization within the body. The patient's protein requirement for each phase was defined as the amount of protein required to achieve a nitrogen balance within ±5, based on the 24-hour collection of UUN. Changes in protein requirements between phases were analyzed. Results : Out of 195 patients, 107 patients with a total of 214 UUN values were included. The mean protein requirement for the entire treatment period was 1.84±0.62 g/kg/day, which is higher than the generally recommended protein supply of 1.2 g/kg/day. As the treatment was tapered, there was a statistically significant increase in the protein requirement from 1.49±0.42 to 2.18±0.60 in phase 2 (p<0.001). Conclusion : Our study revealed a total average protein requirement of 1.84±0.62 g during the treatment period, which falls within the upper range of the preexisting guidelines. Nevertheless, a notable deviation emerged when analyzing the treatment application period separately. Hence, it is recommended to incorporate considerations for the type and timing of treatment, extending beyond the current guideline, which solely accounts for the severity by disease.

• 한국정보통신학회논문지
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• 제14권1호
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• pp.16-22
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• 2010

심전도 신호 분석 및 부정맥 분류는 환자를 진단하고 치료하는데 중요한 역할을 한다. 부정맥은 맥박이 불규칙한 상태로 심실빈맥(VT)이나 심실세동(VF) 환자에게 심각한 위협이 될 수 있다. 심방조기수축(APC)과 상심실성빈맥(SVT), 심실조기수축(PVC)은 심실빈맥(VT)만큼 치명적이지는 않지만 심장질환을 진단하는데 중요한 부정맥이다. 본 논문은 2~3개의 부정맥 분류만을 고려한 기존의 방법을 극복하고 다양한 부정맥을 분류하기 위한 새로운 방법을 제시한다. 심전도 신호의 특징 추출을 위해서 EMD 방법으로 신호를 분해하여 IMFs를 얻는다. 입력 데이터의 양은 분류기 성능에 영향을 미치므로 신호 데이터의 차원을 감소시키기 위해 Burg 알고리즘을 IMFs에 적용하여 AR 계수를 구하고 여러 개의 이진 분류기를 결합한 다중 클래스 SVM의 입력으로 사용한다. 최적의 SVM 성능 파라미터를 선택하고 부정맥 분류에 적용한 결과 검출의 정확성은 96.8%~99.5%였다. 실험 결과는 제안한 EMD 방법에 의한 전처리 및 특징 추출과 다중 클래스 SVM에 의한 부정맥 분류의 유용성을 보여준다.

• Tuberculosis and Respiratory Diseases
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• 제61권1호
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• pp.46-53
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• 2006

연구배경: IAP의 증가는 혈류량을 감소시켜 여러 장기에 영향을 준다. IAH는 IAP가 12 mmHg 이상 또는 APP가 60 mmHg 이하로, ACS는 IAP가 20 mmHg 이상이면서 동시에 하나 이상의 장기 손상이 있는 경우로 각각 정의한다. 저자들은 중환자에서 IAH 및 ACS의 유병률과 이들이 환자의 예후에 미치는 영향을 고찰하고자 하였다. 방 법: 고려대학교 의료원 중환자실에 입원하는 내과계 환자를 대상으로 하여, APACHE II 및 III 점수, SAPS II 점수를 기록하였다. IAP는 삼중관 요도관을 통하여, 입원 7일째까지 매일 3회 측정하였고, 환자가 사망하거나 일반 병실로 전실 또는 요도관을 제거할 때까지 계속하였다. 환자의 예후는 28일을 기준으로 판단하였다. 결 과: 총 111명 대상 환자들의 입원 1일 IAH 및 ACS의 유병률은 각각 47.7%, 15.3%였다. 사망군과 생존군 사이에 IAH의 유병률은 유의한 차이가 없었으나, ACS는 사망군에서 더 높았다 (p=0.004). 사망군에서 IAP는 더 높았고 (p=0.012), APP는 유의하게 낮았다 (p<0.001). 결 론: 중환자에서 입원 1일에 측정한 IAP의 증가, APP의 감소 및 ACS 발생은 환자의 사망과 연관이 있을 것으로 판단된다.

• Clinical and Experimental Pediatrics
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• 제55권8호
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• pp.286-292
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• 2012

Purpose: Continuous renal replacement therapy (CRRT) is becoming the treatment of choice for supporting critically ill pediatric patients. However, a few studies present have reported CRRT use and outcome in neonates weighing less than 3 kg. The aim of this study is to describe the clinical application, outcome, and complications of CRRT in small neonates. Methods: A retrospective review was performed in 8 neonatal patients who underwent at least 24 hours of pumped venovenous CRRT at the Samsung Medical Center in Seoul, Korea, between March 2007 and July 2010. Data, including demographic characteristics, diagnosis, vital signs, medications, laboratory, and CRRT parameters were recorded. Results: The data of 8 patients were analyzed. At the initiation of CRRT, the median age was 5 days (corrected age, $38^{+2}$ weeks to 23 days), and the median body weight was 2.73 kg (range, 2.60 to 2.98 kg). Sixty-two patient-days of therapy were reviewed; the median time for CRRT in each patient was 7.8 days (range, 1 to 37 days). Adverse events included electrolyte disturbances, catheter-related complications, and CRRT-related hypotension. The mean circuit functional survival was $13.9{\pm}8.6$ hours. Overall, 4 patients (50%) survived; the other 4 patients, who developed multiorgan dysfunction syndrome, died. Conclusion: The complications of CRRT in newborns are relatively high. However, the results of this study suggest that venovenous CRRT is feasible and effective in neonates weighing less than 3 kg under elaborate supportive care. Furthermore, for using potential benefit of CRRT in neonates, efforts are required for prolonging filter survival.

• Journal of Preventive Medicine and Public Health
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• 제56권4호
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• pp.319-326
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• 2023

Objectives: The coronavirus disease 2019 (COVID-19) pandemic has increased the workload of healthcare workers (HCWs), impacting their health. This study aimed to assess sleep quality using the Pittsburgh Sleep Quality Index (PSQI) and identify factors associated with poor sleep among HCWs in Vietnam during the COVID-19 pandemic. Methods: In this cross-sectional study, 1000 frontline HCWs were recruited from various healthcare facilities in Vietnam between October 2021 and November 2021. Data were collected using a 3-part self-administered questionnaire, which covered demographics, sleep quality, and factors related to poor sleep. Poor sleep quality was defined as a total PSQI score of 5 or higher. Results: Participants' mean age was 33.20±6.81 years (range, 20.0-61.0), and 63.0% were women. The median work experience was 8.54±6.30 years. Approximately 6.3% had chronic comorbidities, such as hypertension and diabetes mellitus. About 59.5% were directly responsible for patient care and treatment, while 7.1% worked in tracing and sampling. A total of 73.8% reported poor sleep quality. Multivariate logistic regression revealed significant associations between poor sleep quality and the presence of chronic comorbidities (odds ratio [OR], 2.34; 95% confidence interval [CI], 1.17 to 5.24), being a frontline HCW directly involved in patient care and treatment (OR, 1.59; 95% CI, 1.16 to 2.16), increased working hours (OR, 1.84; 95% CI,1.37 to 2.48), and a higher frequency of encountering critically ill and dying patients (OR, 1.42; 95% CI, 1.03 to 1.95). Conclusions: The high prevalence of poor sleep among HCWs in Vietnam during the COVID-19 pandemic was similar to that in other countries. Working conditions should be adjusted to improve sleep quality among this population.

• Journal of Chest Surgery
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• 제30권10호
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• pp.966-972
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• 1997

1994년 6월부터 1996년 8월까지 한림대학교 강동성심병원에서는 총 88례의 관상동맥우회 술을 시행하였 튼데 그중 13례를 응급으로 시행하였다. 응급수술 시행환자의 남녀비는 3:10으로 선택수술의 41:34에 비 하여 여자가 많았으며 나이는 평균 65.5+/-6.3(56-80)세로 선택수술의 58.9+/-10.3(35-82)세와 유의한 차이가 없었다. 응급수술의 적응증은 수회의 심율동전환(cardioversion)에도 반응하지 않는 심실성 빈맥환자 1례를 제외한 12례가 심인성 쇼크였는데 심인성 쇼크의 원인으로는 진행성 심근경색이 6례, 경피적 관상동맥성형술 실패가 4례, 급성 심근경색이 1례, 그리고 급성심근경색후 심실중격파열이 1례를 차지하고 있었다. 13Bl 의 환자중 5례의 환측는 심인성 쇼크가 발생한 후 2시간 이내에 수술을 시작할수 있었으나 나머지 8례의 환자는 3시간 내지 10시간이 지나서야 수술을 시작할수 있었다. 13례의 환자중 12례의 환자에서는 통상의 관상동맥우회 술을 시행하였는데 그중1례에서는 파열된 심실 중격 봉합을 동반시행하였으며 좌주관상동맥에만 국한된 병변이 있었던 1례의 환자에서는 좌주관상동맥 성형술을 실시하였다. 통상의 관상동맥 우 \ulcorner술을 시행한 12례의 환자에서는 37개의 문합을 실시하여 환자 당 평균 3.1개를 실시하였는데 선택적인 수술과는 달리 내흉동맥은 3례의 환자에서만 사용할수 있었으며 나머지는 모두 복제정맥을 이용한 문함을 시행하였다. 수술하는데 필요한 대동맥차단시간은 평군 96+/-25(65-140)분이었으며 인공심폐기 가동시간은 평균 281+/-117(136-592)분으로 손상된 심근의 회복을 위한 심보조시간이 상당부분을 차지하고 있었다. 수술후 5례의 환자가 사망하여(38.5%) 선택수술의 4.0%(3/75)에 비하여 높은 사망률을 보이고 있었으며 사망원인으로는 좌심실기능부전이 3례,심실성 인맥이 1례,그리고 다장기 기능부전이 1례를 차지하고 있 었다. 또한 3례의 환자에서 수술주위 심근경색, 종격동염,그리고 상부위장관출혈, 등의 합병증이 발생하 였으나 별다른 후유증없이 치유되었다. 생존한 환자 8례는 모두 현재 외래에서 특별한 문제없이 추적관 찰중이다. 결론적으로 아직 사망률이 높기는 하지만 심인성 쇼크 등과 같은 중환자들에게서 의 적극적인 치료는 이러한 환자들을 살릴수 있는 유일한 방법이라 생각되며 이러한 치료에 있어서 가장 중요한 점은 심장에 비가역적인 손상이 발생하기 전에 시행하는 조기수술요법이라 생각된다.