• Tuberculosis and Respiratory Diseases
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• v.78 no.1
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• pp.1-7
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• 2015

Background: The incidence of tuberculosis (TB) in Korea is relatively high compared to the other Organisation for Economic Co-operation and Development (OECD) countries, with a prevalence of 71 per 100,000 in 2012, although the incidence is declining. Real-time polymerase chain reaction (PCR) has been introduced for the rapid diagnosis of TB. Recently, its advantage lies in higher sensitivity and specificity for the diagnosis of TB. This study evaluated the clinical accuracy of real-time PCR using respiratory specimens in a clinical setting. Methods: Real-time PCR assays using sputum specimens and/or bronchoscopic aspirates from 2,877 subjects were reviewed retrospectively; 2,859 subjects were enrolled. The diagnosis of TB was determined by positive microbiology, pathological findings of TB in the lung and pleura, or clinical suspicion of active TB following anti-TB medication for more than 6 months with a favorable response. Results: Sensitivity, specificity, and accuracy were 44%, 99%, and 86% from sputum, and 65%, 97%, and 87% from bronchoscopic aspirates, respectively. For overall respiratory specimens, sensitivity was 59%, specificity was 98%, and accuracy increased to 89%. Conclusion: Positivity in real-time PCR using any respiratory specimens suggests the possibility of active TB in clinically suspected cases, guiding to start anti-TB medication. Real-time PCR from selective bronchoscopic aspirates enhances the diagnostic yield much more when added to sputum examination.

• Earthquakes and Structures
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• v.1 no.2
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• pp.147-162
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• 2010

The ground acceleration measured at a point on the earth's surface is composed of several waves that have different phase velocities, arrival times, amplitudes, and frequency contents. For instance, body waves contain primary and secondary waves that have high frequency content and reach the site first. Surface waves are composed of Rayleigh and Love waves that have lower phase velocity, lower frequency content and reach the site next. Some of these waves could be of more damage to the structure depending on their frequency content and associated amplitude. This paper models critical earthquake loads for single-degree-of-freedom (SDOF) inelastic structures considering evolution of the seismic waves in time and frequency. The ground acceleration is represented as combination of seismic waves with different characteristics. Each seismic wave represents the energy of the ground motion in certain frequency band and time interval. The amplitudes and phase angles of these waves are optimized to produce the highest damage in the structure subject to explicit constraints on the energy and the peak ground acceleration and implicit constraints on the frequency content and the arrival time of the seismic waves. The material nonlinearity is modeled using bilinear inelastic law. The study explores also the influence of the properties of the seismic waves on the energy demand and damage state of the structure. Numerical illustrations on modeling critical earthquake excitations for one-storey inelastic frame structures are provided.

• Water Engineering Research
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• v.1 no.2
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• pp.119-127
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• 2000

In the process of crossflow microfiltration, a deposit of cake layer tends to form on the membrane, which usually controls the performance of filtration. It is found, however, that there exist a condition under which no deposit of cake layer is made. This condition is called the sub-critical flux condition, and the critical flux here means a flux below which a decline of flux with time due to the deposit of cake layer does not occur. In order to study the characteristics of the critical flux, a numerical model is developed to predict the critical flux condition, and is verified with experimental results. For development of the model, the concept of effective particle diameter is introduced to find a representative size of various particles in relation to diffusive properties of particles. The model is found to be in good match with the experimental results. The findings from the use of the model include that the critical flux condition is determined by the effective particle diameter and the ratio of initial permeate flux to crossflow velocity.

• Proceedings of the KSME Conference
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• 2003.04a
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• pp.2127-2132
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• 2003

A computational study is performed to better understand the choke phenomenon of unsteady gas flow through a critical nozzle. The axisymmetric, unsteady, compressible, Navier-Stokes equations are solved using a finite volume method. In order to simulate the effects of back pressure fluctuations on the critical nozzle flow, a forced sinusoidal pressure wave is assumed downstream the exit of the critical nozzle. It's frequency is 20kHz and amplitude is varied below 15% of time-mean back pressure. The results obtained show that for low Reynolds numbers, the unsteady effects of the pressure fluctuations can propagate upstream of the throat of critical nozzle, and thereby giving rise to applicable fluctuations of mass flow through the critical nozzle. The effect of the amplitude of the excited pressure fluctuations on the choke phenomenon is discussed in details.

• Journal of Arbitration Studies
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• v.32 no.4
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• pp.103-141
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• 2022

Traditionally, schedule analysis in Korea has been used, mainly through the Critical Path Method, to evaluate the claim for extension of time and/or the amount of liquidated damages for delay. Critical path method, however, cannot identify the delay event and its impact occurred in non-critical path especially in multi facility projects. In multi facility projects that comprise several independent but related facilities or structures, each facility has its own facility critical path the duration of which will be impacted by facility specific critical delays. Thus, only through the non-critical delay analysis along with the critical delay analysis damages not attributable to contractors may be remedied in full. Because all the records and pictures can reveal what has actually happened in post contract review, only the retrospective analysis rather than the prospective analysis based on the assumptions can establish the cause and allocate the each parties' responsibilities appropriately.

• Structural Engineering and Mechanics
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• v.71 no.2
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• pp.139-151
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• 2019

In a project schedule, it is possible to reduce the time required to complete a project by allocating extra resources for critical activities. However, accelerating a project causes additional expense. This issue is addressed by finding optimal set of time-cost alternatives and is known as the time-cost trade-off problem in the literature. The aim of this study is to identify the optimal set of time-cost alternatives using a multiobjective teaching-learning-based optimization (TLBO) algorithm integrated with the non-dominated sorting concept and is applied to successfully optimize the projects ranging from a small to medium large projects. Numerical simulations indicate that the utilized model searches and identifies optimal / near optimal trade-offs between project time and cost in construction engineering and management. Therefore, it is concluded that the developed TLBO-based multiobjective approach offers satisfactorily solutions for time-cost trade-off optimization problems.

• Korean Journal of Construction Engineering and Management
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• v.5 no.6 s.22
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• pp.72-79
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• 2004

Critical Path-based project management has been applied to the construction projects with a goal of delivering projects within original costs and time estimates. These current project management methods, rarely make early finishes of construction Projects. In addition, current practices on time management seems not to take advantages of early finishes concepts due to student syndrome and Parkinson's Law, This research study applied the Theory of Constraints(n) in the estimation of construction project duration. While the TOC includes variety of management techniques, in this study, it refers to critical chain that has been used to develop the specific management technique in scheduling. The concept of critical chain is applied to this study to solve the problems associated with the current scheduling method. The efforts focus to solve the p개blems associated with current construction project scheduling methods by adopting both stochastic estimation technique and the concept of schedule buffer,

• Journal of Information Technology and Architecture
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• v.9 no.4
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• pp.443-453
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• 2012

In order to minimize the damage from system failures, systems over various fields are requested to contain the safety-critical features. In this paper, we deliver the considerable issues, especially, in the cyber physical systems that is recently used as a safety-critical system, as well as we propose the model driven architecture based on time as its the important factor. Based on meta-modeling approach, we introduce the time-based architecture which is associated with deadline, transition state, and threshold, and also we work out a design for this by using model driven architecture. We propose a realizable safety-critical architecture by means of showing failure handling components with safety transaction model from the meta-model. In the detailed models and the example, we design a basic safety processing state, a multiple safety processing state, and a compound safety processing state for completing the safety-critical system architecture.

• Progress in Superconductivity and Cryogenics
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• v.8 no.1
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• pp.39-44
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• 2006

Before applying HTS power cable to the real utility. system analysis should be carried out by some simulation tools . Hereby the electrical power system analysis is very important for practical use of HTS devices. Nowadays PSCAD/EMTDC simulation tool is one of the most popular and useful analysis tool for the electrical power system analysis. Unfortunately the model component for HTS power cable is not provided in the PSCAD/EMTDC simulation tool In this paper. the EMTDC model component for HTS power cable has been developed considering critical current, critical temperature and recovery time constant that depend on the sorts of HTS wire. The numerical model of HTS Power cable in PSCAD/EMTDC was designed by using the real experimented data obtained from the real HTS 1G wire test. The utility application analysis of HTS power cable was also performed using the developed model component and the parameters of the real utility network in this study. The author's got good results. The developed model component for HTS power cable could be variously used when the power system includes HTS power cable, especially it will be readily analyzed by PSCAD/EMTDC in order to obtain the data for the level of fault current power flow, and power losses, and so on.

• Structural Engineering and Mechanics
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• v.24 no.5
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• pp.621-639
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• 2006

Stability of a cylindrical shell subject to a uniform axial compression, which is a power function of time, is examined within the framework of small strain elasto-plasticity. The material of the shell is incompressible and the effect of the elastic unloading is considered. Initially, employing the infinitesimal elastic-plastic deformation theory, the fundamental relations and Donnell type stability equations for a cylindrical shell have been obtained. Then, employing Galerkin's method, those equations have been reduced to a time dependent differential equation with variable coefficient. Finally, for two initial conditions applying a Ritz type variational method, the critical static and dynamic axial loads, the corresponding wave numbers and dynamic factor have been found. Using those results, the effects of the variations of loading parameters and the variations of power of time in the axial load expression as well as the variations of the radius to thickness ratio on the critical parameters of the shells for two initial conditions are also elucidated. Comparing results with those in the literature validates the present analysis.