• KDI Journal of Economic Policy
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• 제38권2호
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• pp.45-62
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• 2016

This paper analyzes changes in the export potential and competitiveness of China, Japan, and Korea. The analysis of Japan's export market share reveals that in sectors where Korea's potential was strong in the early 1990s, Japan's market share diminished. This suggests the possibility that Korea was catching up with Japan, eating into Japan's market share. The same analysis of Korea's export market share in the 2000s shows, for items in which China's export potential was high, Korea's market share has declined comparatively since 2010, with the tendency growing much larger. China's export potential continues to expand in markets for Korea's key export products, making it difficult to rule out the possibility that Korea's competitiveness in key export products will be hindered, driven by the catching up of China. To respond to these challenges, it is important for Korea continuously to foster and enhance creative and core capabilities that latecomers will not easily be able to emulate.

• 한국지구과학회지
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• 제23권4호
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• pp.324-333
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• 2002

최근의 연구들은 과학영역에서 남학생이 여학생에 비해 훨씬 더 높은 학업 성취도를 보인다고 주장하고, 과학영역에서의 창의성 측면에서도 남학생이 여학생에 비해 더 높은 창의적 성취를 보일 것이라는 것이 일반적인 통념이다. 과학영재교육이 본격화되고 남${\cdot}$여 과학영재들의 창의적 특성에 대한 이해의 중요성이 부각되고 있지만, 이를 뒷받침할 연구들은 거의 부재한 상황이다. 본 연구에서는 135명의 과학영재학생들을 대상으로 창의성의 다양한 영역에서, 특히 확산적 사고라는 영역 보편적 입장과 과학에서의 창의적 행동특성과 문제해결 및 발견이라는 영역 특수적 입장에서, 남학생과 여학생간의 창의성의 차이를 살피고 창의성의 본성에 대한 이해를 돕고자 했다. 본 연구의 결과는 과학 영재여학생들이 남학생들에 비해 모든 영역에서 유의미하게 큰 차이를 보이지는 않았지만, 전반적으로 창의성의 세 영역 모두에서 상대적으로 높은 성취를 보이는 것으로 나타났다. 구체적으로 살펴보면 확산적 사고의 융통성, 제목의 추상성, 정교성 영역에서, 과학에서의 창의적 문제 해결력 및 문제 발견력을 측정하는 CPSF의 가설 설정 능력의 유창성과 독창성 영역에서, 그리고 과학에서의 창의적 행동 특성을 측정하는 CBCS에서 개방성, 심미안에서 과학 영재 여학생이 남학생보다 유의미하게 창의성이 높은 것으로 나타났다. 남학생은 여학생에 비해 CBCS에서의 '과학적 호기심' 문항에서만 유의미하게 더 높은 창의성 점수를 보임으로 본 연구 결과는 '남학생이 여학생보다 더 창의적이다'라는 사회의 일반적인 통념과 상반된 결과를 보였다.

• Journal of Microbiology and Biotechnology
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• 제32권12호
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• pp.1547-1552
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• 2022

β-Amyrin is a pentacyclic triterpene widely distributed in leaves and stems worldwide. The ability of β-amyrin to induce the production of reactive oxygen species (ROS) in microorganisms suggests its potential as an antimicrobial agent. Thus, this study aimed to elucidate the antibacterial mode of action of β-amyrin. We treated Escherichia coli cells with β-amyrin and found that it triggered ROS accumulation. Excessive stress caused by ROS, particularly hydroxyl radicals, induces glutathione (GSH) dysfunction. GSH protects cells from oxidative and osmotic stresses; thus, its dysfunction leads to membrane depolarization. The resultant change in membrane potential leads to the release of apoptotic proteins, such as caspases. The activated caspases-like protein promotes the cleavage of DNA into single strands, which is a hallmark of apoptosis-like death in bacteria. Apoptotic cells usually undergo events such as DNA fragmentation and phosphatidylserine exposure, differentiating them from necrotic cells, and the cells treated with β-amyrin in this study were positive for annexin V and negative for propidium iodide, indicating apoptosis-like death. In conclusion, our findings suggest that the antibacterial mode of action of β-amyrin involves the induction of ROS, which resulted in apoptosis-like death in E. coli.

• International Journal of Computer Science & Network Security
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• 제24권5호
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• pp.165-171
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• 2024

The processes of society's informatization and digitalization necessitate the widespread use of new pedagogical technologies. Through these technologies, comprehensive disclosure of didactic functions of new methods of educational activity and the realization of the potential and creative potential. The use of information and computer multimedia technologies in teaching music art is especially relevant in the intensification of the development of interactive technologies, the transition to mixed forms of learning, and a period of socio-economic and sociopolitical upheavals. The study aims to substantiate the theoretical and applied principles of the analysis of multimedia technology learning musical art in modern conditions and assess the status and trends in their use in conducting educational activities. The study uses general scientific and unique methods of economic analysis, in particular, analysis and synthesis, analogy and comparison, generalization and systematization, and graphic ways. Regarding the results of the study of multimedia technologies for teaching musical art in current conditions, it was found that they contribute to the development of the seeker's creative, creative, and cognitive activity, have a positive impact on learning material, and diversify the educational process. Multimedia technologies such as presentations, programs for watching a video, listening to audio, music and singing karaoke, electronic encyclopedias, and Internet resources are proven to be the most used in music education. They have several qualitative and quantitative advantages, manifested in the possibilities of audio-visual presentation of educational material and significantly higher information density. It is suggested to strengthen the use of such computer programs as Microsoft Word, Ahead Nero, Finale, Adobe Audition, Sound Forge, and Microsoft PowerPoint for musical art classes.

• Journal of Information Display
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• 제2권3호
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• pp.48-53
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• 2001

Carbon nanotube emitters, prepared by screen printing, have demonstrated a great potential towards low-cost, largearea field emission displays. Carbon nanotube paste, essential to the screen printing technology, was formulated to exhibit low threshold electric fields as well as an emission uniformity over a large area. Two different types of triode structures, normal gate and undergate, have been investigated, leading us to the optimal structure designing. These carbon nanotube FEDs demonstrated color separation and high brightness over 300 $cd/m^2$ at a video-speed operation of moving images. Our recent developments are discussed in details.

• 전자공학회논문지
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• 제53권8호
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• pp.136-144
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• 2016

일반적으로 임베디드 소프트웨어 교육을 위해 다양한 교구와 학습 방법이 개발 및 활용이 되고 있다. 본 논문에서는 임베디드 소프트웨어 공학교육에서 요구되고 있는 창의적 문제해결 방법을 학습하기 위하여 스마트 로봇을 활용하고자 한다. 스마트 로봇을 사용한 창의적 공학교육으로 그 NCS 직무교육 효과를 분석하고 임베디드 소프트웨어교육 향상을 위하여 RSPM(Robot Based Software Programming Method) 공학교육 방법에 대해 제시한다. 임베디드 소프트웨어 공학교육에서 좀 더 창의적이고 소프트웨어 코딩 능력향상을 위해 스마트 로봇인 EV3 시스템을 활용하였다. 본 논문에서는 임베디드 소프트웨어 공학교육에 미치는 정도, 흥미, 프로그램 능력 향상과 영향에 대하여 설문 및 분석을 통하여 창의적인 RSPM 공학교육과정을 통하여 EV3 시스템을 교구로 활용하여 성공적인 임베디드 소프트웨어 코딩 능력 가능성에 대해 제시하고자 한다. 특히 RSPM 공학교육은 스마트 로봇 NCS 직무로써 미래 유망한 임베디드 소프트웨어분야의 직업인으로 성장할 수 있도록 경쟁력을 갖춘 기초 스마트로봇 직무학습 중심으로 구성하였다.

• Environmental Analysis Health and Toxicology
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• 제31권
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• pp.16.1-16.9
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• 2016

Objectives Banha-sasim-tang (BST), which consists of seven different herbs, is one of the most popular herbal formulae for treating gastrointestinal disorders in Eastern Asia. The commonly used herbal medicine is often co-administered with other therapeutic drugs, which raises the possibility of herb-drug interactions and may modify the clinical safety profile of therapeutic drugs. Methods We investigated the potential herb-drug interactions between BST extract and midazolam (MDZ) in mice. The area under the plasma concentration-time curve (AUC) of MDZ and 1'-hydroxymidazolam (1'-OH-MDZ) was evaluated for both oral and intraperitoneal administration of MDZ, following oral administration of BST (0.5 and 1 g/kg). Results It was found that the AUC of MDZ and 1'-OH-MDZ was lower in case of oral administration of MDZ. Administration of BST extract was not associated with hepatic cytochrome P450 activity. BST extract induced a strong reduction in pH and it has been reported that oral mucosal absorption of MDZ is lower at low pH. The decreased absorption rate of MDZ might be caused by the ingredients of BST and may not be related to other factors such as increased excretion of MDZ by P-glycoprotein. Conclusions The altered pharmacokinetics of midazolam caused by co-administration with BST in vivo could be attributed to a decrease in pH and subsequent reduction of MDZ absorption rate.

• 한국과학교육학회지
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• 제22권1호
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• pp.158-175
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• 2002

In the present study we have compared and analyzed three different measures of creativity in 135 gifted and 161 normal students to understand the nature of creativity and to propose the guideline for measuring creativity. The instruments used to measure creativity in this study are the Torrance Test of Creativity Thinking (TTCT), the Test of Creative Problem solving and Finding in Science (CPFS), and the Creative Behavior Checklist in Science (CBCS). The TTCT is the most widely used divergent thinking test and measures creativity in the aspect of domain-generality. The CPFS and the CBCS were developed for the purpose of this study and measure domain-specific creativity in the area of Science. The findings of this study revealed that gifted students are significantly more creative compared to normal students in all measures of creativity used in the study. The biggest difference between the gifted and normal students was found in the aspect of CPFS. This study implies that creativity, which is considered less useful to identify gifted students compared to achievement or IQ scores, is the important factor to consider for judging giftedness. The low correlations revealed among the TTCT, CPFS, and CBCS imply that the three measures of creativity address relatively different aspects of creativity. The results also suggest that it is essential to consider multiple criteria of creativity not to overlook potential creative students in the area of science. Implications of the study in connection with the identification and educational practices for gifted education program is discussed.

• 한국경제지리학회지
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• 제17권1호
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• pp.28-44
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• 2014

글로컬라이제이션의 시대가 도래함에 따라, 세계는 각각의 지역이 가진 고유의 매력을 발굴하여 지역의 경쟁력을 강화시키기 위해 노력하고 있다. 본 연구는 창조적 지역재생의 관점에서 장소마케팅과 장소자산이 어떠한 특징을 갖는가 하는 고민에서 시작되었다. 특히 장소자산의 구성요소로서 '예술'을 독립된 콘텐츠로 인식하고, 새로운 지역재생과 지역경제 활성화의 수단으로서 어떻게 도입되고 사용되는지에 대해서 살펴보고자 한다. 이를 위해 장소자산에 대한 기존 연구에 대한 검토를 바탕으로 예술자산의 개념을 새롭게 정리하였으며, 유형별로 분류하고 각각의 사례를 살펴보았다. 이를 통해 궁극적으로 지역재생의 창조적 장소자산으로서 예술자산의 가능성과 활용가치를 검토하고자 한다.

• Mass Spectrometry Letters
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• 제10권2호
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• pp.61-65
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• 2019

Korean ginseng (Panax ginseng Meyer) is a traditional herb used across the world to treat various diseases. Although, red ginseng is this herb's most famous product and has demonstrated diverse pharmacological activities, white ginseng (WG) is another ginseng product that is made fresh and individually regulated in Eastern Asia. Red and white ginseng show different characteristics due to distinct processing steps despite originating from the same plant, and the drug interactions induced by WG have not been well documented. Selegiline is a selective monoamine oxidase (MAO) inhibitor used as an antidyskinetic and antiparkinsonian agent. Here we developed a quantification method for selegiline in mouse plasma using a C8 stationary phase in triple quadrupole-mass spectrometry (LC-MS/MS) with multiple reaction monitoring (MRM). The validated LC-MS/MS method was successfully applied to determine the potential interaction with WG extract (0.1 g/kg/day) pre-administered for 4 weeks. The $AUC_{0-240min}$ of selegiline was altered due to a decrease in the absorption of selegiline with repeated administration of WG extract.