• Journal of Acupuncture Research
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• v.19 no.5
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• pp.10-27
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• 2002

연구목적 : 면역억제와 활성 작용을 지닌 것으로 알려진 녹용약침(CPH)을 type II collagen 유발 관절염 (CIA) 백서와 인산이온 유발 연골세포의 세포사에 있어 보호활성 효과를 연구하였다. 연구방법 : 7주된 암컷 Sprague-Dawley 쥐를 collagen으로 관절염을 유발시킨 후 CPH의 효과를 관절염 점수, 체중감소 등의 평가기준으로 검정하였다. CPH는 일주일에 5번씩 각각 10, 20, 30 및 $100{\mu}g/kg/day$의 용량으로 양측 신수혈에 주입하였다. 연구결과 : 1. 300 mg/kg/day CPH처리로 관절염점수의 감소를 기초로 한 collagen 유발 관절염의 발생을 완전히 억제하였으며 관절염 점수상에서 CPH의 효과작인 용량은 64 mg/kg이었다. 2. CHP는 쥐의 간에 있는 DHO-DHase 활성을 $Ki=843{\pm}43{\mu}g/ml$의 비교적 높은 비활성으로 억제하였다. 3. 관절염관련 세포의 증식억제활성을 검정한 결과 CPH의 항 증식효과는 세포주기 S기에서 정지시키는 활성을 나타내었다. 4. 쥐의 늑연골로부터 완전히 최종 분화된 비대연골세포를 분리 배양하여 3~5mM/L Pi를 첨가함으로서 세포사멸을 측정하였다. $10{\mu}g/ml$ CPH 처리에 의한 보호(억제) 효과가 Pi-유발 연골세포의 세포사에 대한 Na-Pi cotransport의 경쟁적 저해제로 알려진 phosphonoformic acid(PFA)의 억제활성과 상응하는 수준으로 CPH의 활성을 확인하게 되었다.

• Proceedings of the Korea Crystallographic Association Conference
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• 2002.11a
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• pp.30-30
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• 2002

Heating [Cp＊Rh(η²-NO₃)(OTf) (1) and PhC≡CPh in EtOH for 3 h gave a η⁴-cyclobutadienerhodium complex, [Cp＊Rh(η⁴-C₄Ph₄)] (2). Complex 1 reacted with HC=CPh in acetone at room temperature for 3 h to give a (η⁴-cyclobutadiene)-rhodium complex, [Cp＊Rh(η⁴-C₄HPhC=CPh)] (3). Whereas, the reactions of 1 with HC=CCH₂Cl in acetone at room temperature for 3 h gave the triply halide-bridged dinuclear rhodium complex, [Cp＊Rh(μ₂-Cl)₃RhCp＊](OTf) (4). Complexes 2-4 have been structurally characterized by X-ray diffraction.

• Asian-Australasian Journal of Animal Sciences
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• v.26 no.3
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• pp.433-442
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• 2013

This study aimed to compare the dynamics of air temperature and velocity under two different ventilation and housing systems during summer and winter in Korea. The $NH_3$ concentration of both housing systems was also investigated in relation to the pig's growth. The ventilation systems used were; negative pressure type for the enclosed pig house (EPH) and natural airflow for the conventional pig house (CPH). Against a highly fluctuating outdoor temperature, the EPH was able to maintain a stable temperature at 24.8 to $29.1^{\circ}C$ during summer and 17.9 to $23.1^{\circ}C$ during winter whilst the CPH had a wider temperature variance during summer at 24.7 to $32.3^{\circ}C$. However, the temperature fluctuation of the CPH during winter was almost the same with that of EPH at 14.5 to $18.2^{\circ}C$. The NH3 levels in the CPH ranged from 9.31 to 16.9 mg/L during summer and 5.1 to 19.7 mg/L during winter whilst that of the EPH pig house was 7.9 to 16.1 mg/L and 3.7 to 9.6 mg/L during summer and winter, respectively. These values were less than the critical ammonia level for pigs with the EPH maintaining a lower level than the CPH in both winter and summer. The air velocity at pig nose level in the EPH during summer was 0.23 m/s, enough to provide comfort because of the unique design of the inlet feature. However, no air movement was observed in almost all the lower portions of the CPH during winter because of the absence of an inlet feature. There was a significant improvement in weight gain and feed intake of pigs reared in the EPH compared to the CPH (p<0.05). These findings proved that despite the difference in the housing systems, a stable indoor temperature was necessary to minimize the impact of an avoidable and highly fluctuating outdoor temperature. The EPH consistently maintained an effective indoor airspeed irrespective of season; however the CPH had defective and stagnant air at pig nose level during winter. Characteristics of airflow direction and pattern were consistent relative to housing system during both summer and winter but not of airspeed. The ideal air velocity measurement favored the EPH and therefore can be appropriate for the Korean environment. Further emphasis on its cost effectiveness will be the subject of future investigations.

• Journal of Korea Entertainment Industry Association
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• v.13 no.8
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• pp.583-593
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• 2019

The purpose of this study was to investigate the relation between and subjective instability pain behavior (SIPB) and physical instability test(PIT) according to the presence of characteristic past histories(CPH) in people with chronic low back pain(CLBP). Forty CLBP subjects participated in this study. The presence of four characteristics past histories(long term history, traumatic experience, sports activities, neurologic sign) were examined. According to presence number(PN) of CPH, subjects were divided into 5 groups[group 1(PN:0): n=8, group 2(PN:1): n=8, group 3(PN:2): n=8, group 4(PN:3): n=8, group 5(PN:4): n=8]. After 16 items were examined for the SIPBs, then Seven PITs were conducted, and the results were scored. The SIPBs and PITs were compared according to the presence numbers of CPH, and the relation between them was analyzed. There was a significant difference(p<.05) in both SIPB scores and PIT scores in the comparison of groups according to the presence number of CPH. There was high positive correlation between the presence numbers of CPH and SIPB score(r=.819, p=.000) and PIT score(r=.606, p=.000). Also, there was a correlation between SIPB score and PIT score(r=.571, p=.000). Based on the findings in the present study, the presence of three or more CPH in people with CLBP may be a useful variable in the diagnosis of lumbar instability. The combined findings of the three variables such as CPH, SIPB, and PIT can improve the accuracy of lumbar instability diagnosis.

• The Korean Journal of Nuclear Medicine
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• v.17 no.2
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• pp.49-55
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• 1983

By radioimmunoassay, serologic markers of Hepatitis B Virus were studied in 44 patients with acute viral hepatitis, 10 patients with chronic persistent hepatitis, 10 patients with chronic active hepatitis, 44 patients with liver cirrhosis and 25 patients with primary hepato cellular carcinoma. The results were follows: 1) HBsAg was present in 77.2% of AVH, 40% of CPH, 80% of CAH, 55.1% of LC and 68 % of PHC. In this HBsAg positive groups, all but one in liver cirrhosis had Anti-HBc. 2) Anti-HBs was most commonly detected in CPR and accompanied by Anti-HBc except one case in AVH. 3) Anti-HBc was the only marker detected in 11.4% of AVH, 20% of CPH, 20% of CAH, 16.3% of LC and 8% of PHC. 4) HBeAg was most commonly found in HBsAg-positive CPH but Anti-HBe was most frequently detected in PHC. 5) The absence of HBV markers was noted in 2.3% of AVH, 10% of CPH, 8% of PHC except CAH and LC.

• Journal of Microbiology and Biotechnology
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• v.16 no.9
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• pp.1441-1447
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• 2006

The light perception and phototransformation of phytochromes are the first process of the phytochrome-mediated light signal transduction. The chromophore ligation and its photochromism of various site-specific and deletion mutants of pea phytochrome A and bacterial phytochrome-like protein (Cph1) were analyzed in vitro. Serial truncation mutants from the N-terminus and C-terminus indicated that the minimal N-terminal domain for the chromophore ligation spans from the residue 78 to 399 of pea phytochrome A. Site-specific mutants indicated that several residues are critical for the chromophore ligation and/or photochromism. Histidine-324 appears to serve as an anchimeric residue for photochromism through its H-bonding function. Isoleucine-80 and arginine-383 playa critical role for the chromophore ligation and photochromism. Arginine-383 is presumably involved in the stabilization of the Pfr form of pea phytochrome A. Apparently, the amphiphilic ${\alpha}$-helix centered around the residue-391 is in the chromophore pocket and critical for the chromophore ligation.

• Asian-Australasian Journal of Animal Sciences
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• v.28 no.3
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• pp.343-350
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• 2015

Cocoa pod is among the by-products of cocoa (Theobroma cacao) plantations. The aim of this study was to apply a number of treatments in order to improve nutritional quality of cocoa pod for feeding of ruminants. Cocoa pod was subjected to different treatments, i.e. C (cocoa pod without any treatment or control), CAm (cocoa pod+1.5% urea), CMo (cocoa pod+3% molasses), CRu (cocoa pod+3% rumen content) and CPh (cocoa pod+3% molasses+Phanerochaete chrysosporium inoculum). Analysis of proximate and Van Soest's fiber fraction were performed on the respective treatments. The pods were then subjected to an in vitro digestibility evaluation by incubation in rumen fluid-buffer medium, employing a randomized complete block design (n = 3 replicates). Further, an in vivo evaluation of the pods (35% inclusion level in total mixed ration) was conducted by feeding to young Holstein steers (average body weight of $145{\pm}3.6kg$) with a $5{\times}5$ latin square design arrangement (n = 5 replicates). Each experimental period lasted for 30 d; the first 20 d was for feed adaptation, the next 3 d was for sampling of rumen liquid, and the last 7 d was for measurements of digestibility and N balance. Results revealed that lignin content was reduced significantly when cocoa pod was treated with urea, molasses, rumen content or P. chrysosporium (p<0.01) with the following order of effectiveness: CPh>CAm>CRu>CMo. Among all treatments, CAm and CPh treatments significantly improved the in vitro dry matter and organic matter digestibility (p<0.05) of cocoa pod. Average daily gain of steers receiving CAm or CPh treatment was significantly higher than that of control (p<0.01) with an increase of 105% and 92%, respectively. Such higher daily gain was concomitant with higher N retention and proportion of N retention to N intake in CAm and CPh treatments than those of control (p<0.05). It can be concluded from this study that treatment with either urea or P. chrysosporium is effective in improving the nutritive value of cocoa pod.

• 한국정보통신설비학회:학술대회논문집
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• 2002.08a
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• pp.233-237
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• 2002

차세대 지능망은 지능망서비스교환기(SSP:Service Switching Point), 지능망서비스제어 시스템(SCP:Service Control Point), 지능형정보제공 시스템(IP:Intelligent Peripheral)간의 시스템 연동으로 구성되며, 각 망 요소들은 지능망 서비스를 제공하기 위한 필요 기능들을 지원한다, 현재 KT는 ITU-TCS(Capability Set)-1 기반의 지능망 서비스를 제공하고 있으나 다양한 종류 즉, 회의통화 서비스나 선불카드 서비스에서 다자간의 호연결 기능 등이 요구될 때 그 한계점을 갖는다. CS-2 기반의 지능망으로 발전하면서 SSP는 CPH(Call Party Handling) 기능이 추가된다. CPH는 하나의 호에 대해 다자간 호를 관리할 수 있는 능력을 말한다. 이런 CPH 기능을 제공할 수 있어 CS-2 기반으로 발전된 차세대 지능망은 더욱 다양한 서비스를 고객에게 제공할 수 있게 된다. 본 논문은 CS-2 기반의 차세대 지능망 서비스의 기능에 대해 분석하고 분석된 결과를 확인하기 위한 메시지 흐름을 도식화 하였다. 또한 회의통화서비스를 분석된 지능망 기능을 적용하여 설명하였다.

• Korean Journal of English Language and Linguistics
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• v.1 no.3
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• pp.437-456
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• 2001

This paper raises a question on the theoretical background behind the English education at the elementary school level. The Critical Period Hypothesis (CPH), supporting the common belief of the earlier the better in foreign language learning, which has promoted the strong trend toward teaching English in Korean elementary schools, is analyzed to determine whether it provides a comprehensible picture to explain age-related factors and whether it is a valid hypothesis which can be applicable in an EFL situation such as Korea. This paper concludes that CPH itself is still considered as an impending hypothesis full of unresolved issues and that the present educational situation of Korean elementary schools is rather far from the environment in which the ideas of CPH could practically apply, and thus it may be desirable to find alternative theoretical backgrounds from which the educational programs can be developed and further expanded.

• Korean Journal of English Language and Linguistics
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• v.1 no.4
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• pp.587-608
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• 2001

When teaching English in elementary schools was introduced in Korea in 1997, the theoretical basis was the critical period hypothesis (CPH). The object of this study was to test whether the Korean situation satisfies the conditions for the CPH such as the amount of English input and needs. As a test for this, English input and needs were compared in Korea, the U.S.A. and Singapore. The items for English input were on a continuum of primary to secondary sources and the items for English needs were on a continuum of immediate to future needs. The 0-5 scale was used. The result showed that the total means of English input were 4.87, 4.62, and 1.05 for children in the U.S.A., Singapore and Korea respectively. The total means of English needs were 4.32, 3.81, and 1.52 for children in the U.S.A., Singapore and Korea respectively. These figures show that Korean children's levels of both input and needs were from “almost none” to “little,” while those of children in the U.S.A. and Singapore were from “much” to “very much.” This shows that teaching English in Korea presently is far from meeting the conditions that are expected by the CPH. As an alternative to explain what happens cognitively to Korean children, this paper suggests the automatization and proceduralization processes.