• Title/Summary/Keyword: Cox proportional hazard

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Factors Influencing Commuting Time to Work for the Simple Linkage Travel (단순연계 출근통행시간에 미치는 요인분석)

  • Bin, Mi-Yeong
    • Journal of Korean Society of Transportation
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    • v.29 no.4
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    • pp.29-41
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    • 2011
  • This study investigates the factor that influences commuting time to work when individuals allocate their time for different types of activities. The commuting time is an important indicator for an individual to determine the residence and choose the means of transportation. The analysis uses the data collected from people who live in Seoul metropolitan area including Seoul, Incheon and Gyeonggi Province, and commute to work and making the simple linkage travel (home-work-home) within the area. For the analysis, the Cox hazard proportional methodology was adopted. The method is known to be well applied without assuming any distribution in case of the dependent variable being continuous. For the covariate, the interaction effect between the space variable of the work place and the variable of transportation has been also included in the model. The commuting time to work has been estimated for both 1) the whole metropolitan area and 2) the separate regions i.e., Seoul, Incheon and Gyeonggi-Do. The result reveals that characteristic variables related to individual, household and travel properties influence the mode of transportation and the time allocated for commuting to work (p<0.01). This study also demonstrates the usefulness of the Cox hazard proportional model. The data used in this study is the actual household travel data surveyed in 2006 in the metropolitan area, and analyzing the survey data in 2010 is currently in progress. Comparison of the two survey data sets seeking any behavioral change is suggested for the future study.

Bayesian Variable Selection in the Proportional Hazard Model

  • Lee, Kyeong-Eun
    • Journal of the Korean Data and Information Science Society
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    • v.15 no.3
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    • pp.605-616
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    • 2004
  • In this paper we consider the proportional hazard models for survival analysis in the microarray data. For a given vector of response values and gene expressions (covariates), we address the issue of how to reduce the dimension by selecting the significant genes. In our approach, rather than fixing the number of selected genes, we will assign a prior distribution to this number. To implement our methodology, we use a Markov Chain Monte Carlo (MCMC) method.

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비례위험모형에서 비례성 가정에 대한 검정: 도산모형에의 응용

  • Nam Jae-U;Kim Dong-Seok;Lee Hoe-Gyeong
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 2004.10a
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    • pp.615-618
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    • 2004
  • The previous quantitative bankruptcy prediction models cannot include time dimension. To overcome this limit, various dynamic models using survival analysis are developed recently. This paper emphasizes that the proportionality assumption must be adapted with caution when the Cox's proportional hazard model is used to explain bankruptcy. It is shown that a non-proportional hazard model including a change point model is a proper alternative, when the proportionality assumption is violated by the change of macroeconomic environment, such as the financial crisis in 1997.

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Prognostic Factors for Survival in Patients with Breast Cancer Referred to Omitted Cancer Research Center in Iran

  • Baghestani, Ahmad Reza;Shahmirzalou, Parviz;Zayeri, Farid;Akbari, Mohammad Esmaeil;Hadizadeh, Mohammad
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.12
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    • pp.5081-5084
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    • 2015
  • Background: Breast cancer is a malignant tumor that starts from cells of the breast and is seen mainly in women. It's the most common cancer in women worldwide and is a major threat to health. The purpose of this study was to fit a Cox proportional hazards model for prediction and determination of years of survival in Iranian patients. Materials and Methods: A total of 366 patients with breast cancer in the Cancer Research Center were included in the study. A Cox proportional hazard model was used with variables such as tumor grade, number of removed positive lymph nodes, human epidermal growth factor receptor 2 (HER2) expression and several other variables. Kaplan-Meier curves were plotted and multi-years of survival were evaluated. Results: The mean age of patients was 48.1 years. Consumption of fatty foods (p=0.033), recurrence (p<0.001), tumor grade (p=0.046) and age (p=0.017) were significant variables. The overall 1- year, 3-year and 5-year survival rates were found to be 93%, 75% and 52%. Conclusions: Use of covariates and the Cox proportional hazard model are effective in predicting the survival of individuals and this model distinguished 4 effective factors in the survival of patients.

Comparison between Parametric and Semi-parametric Cox Models in Modeling Transition Rates of a Multi-state Model: Application in Patients with Gastric Cancer Undergoing Surgery at the Iran Cancer Institute

  • Zare, Ali;Mahmoodi, Mahmood;Mohammad, Kazem;Zeraati, Hojjat;Hosseini, Mostafa;Naieni, Kourosh Holakouie
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.11
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    • pp.6751-6755
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    • 2013
  • Background: Research on cancers with a high rate of mortality such as those occurring in the stomach requires using models which can provide a closer examination of disease processes and provide researchers with more accurate data. Various models have been designed based on this issue and the present study aimed at evaluating such models. Materials and Methods: Data from 330 patients with gastric cancer undergoing surgery at Iran Cancer Institute from 1995 to 1999 were analyzed. Cox-Snell Residuals and Akaike Information Criterion were used to compare parametric and semi-parametric Cox models in modeling transition rates among different states of a multi-state model. R 2.15.1 software was used for all data analyses. Results: Analysis of Cox-Snell Residuals and Akaike Information Criterion for all probable transitions among different states revealed that parametric models represented a better fitness. Log-logistic, Gompertz and Log-normal models were good choices for modeling transition rate for relapse hazard (state $1{\rightarrow}state$ 2), death hazard without a relapse (state $1{\rightarrow}state$ 3) and death hazard with a relapse (state $2{\rightarrow}state$ 3), respectively. Conclusions: Although the semi-parametric Cox model is often used by most cancer researchers in modeling transition rates of multistate models, parametric models in similar situations- as they do not need proportional hazards assumption and consider a specific statistical distribution for time to occurrence of next state in case this assumption is not made - are more credible alternatives.

Analysis of stage III proximal colon cancer using the Cox proportional hazards model (Cox 비례위험모형을 이용한 우측 대장암 3기 자료 분석)

  • Lee, Taeseob;Lee, Minjung
    • Journal of the Korean Data and Information Science Society
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    • v.28 no.2
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    • pp.349-359
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    • 2017
  • In this paper, we conducted survival analyses by fitting the Cox proportional hazards model to stage III proximal colon cancer data obtained from the Surveillance, Epidemiology, and End Results program of the National Cancer Institute. We investigated the effect of covariates on the hazard function for death from proximal colon cancer in stage III with surgery performed and estimated the survival probability for a patient with specific covariates. We showed that the proportional hazards assumption is satisfied for covariates that were used to analyses, using a test based on the Schoenfeld residuals and plots of the Schoenfeld residuals and $log[-log\{{\hat{S}}(t)\}]$. We evaluated the model calibration and discriminatory accuracy by calibration plot and time-dependent area under the ROC curve, which were calculated using 10-fold cross validation.

The Factors Affecting the Marital Duration (결혼지속에 영향을 미치는 요인에 관한 연구)

  • Hong, Baeg-Eui;Park, Eun-Joo;Park, Hyun-Jung;Bahk, Jin
    • Korean Journal of Social Welfare
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    • v.61 no.3
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    • pp.307-328
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    • 2009
  • This study aims to investigate the patterns and causes of the marital duration. Data used for this study are ten waves of Korean Labor and Income Panel Study(KLIPS) in 1998~2007, in which the final sample consists of 2,397 households. The Life-table method is used for describing the overall patterns of marital duration by birth-cohorts and different education groups, and the Cox proportional hazard regression model is used to identify significant factors on the marital duration. The results show that among the all respondents, the 0.79% has divorced or separated within five years after marriage, 2.12% within 10 years, and 5.84% within 20 years, respectively. In addition, the Cox regression results show that the marital duration is significantly affected by the birth-cohorts of respondents and their spouses, education level, earning of spouses, co-residence with parents, and household income. This implies that the hazard rate of marital disruption is higher for younger cohorts, individuals with lower education and economic status, persons living with parents-in-law, compared to their counterparts. Thus, it is necessary to implement social welfare policies applicable for these persons.

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Review on proportional hazards regression diagnostics based on residuas (잔차에 기초한 비례위험모형의 회귀진단법 고찰 - PBC 자료를 통한 응용 연구)

  • 이성임;박성현
    • The Korean Journal of Applied Statistics
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    • v.15 no.2
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    • pp.233-250
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    • 2002
  • Cox's proportional hazard model is highly-used for the regression analysis of survival data in various fields. Regression diagnostics for the proportional hazards model, however, is not as well-known as the diagnostics for the classical linear models and so these diagnostic methods are not used widely in our practical data analyses. For this reason, we review the residuals proposed by several authors, and investigate how to use them in assessing the model. We also provide the results and interpretation with the analysis of PBC data using S-plus 2000 program.

A Study on the Conditional Survival Function with Random Censored Data

  • Lee, Won-Kee;Song, Myung-Unn
    • Journal of the Korean Data and Information Science Society
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    • v.15 no.2
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    • pp.405-411
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    • 2004
  • In the analysis of cancer data, it is important to make inferences of survival function and to assess the effects of covariates. Cox's proportional hazard model(PHM) and Beran's nonparametric method are generally used to estimate the survival function with covariates. We adjusted the incomplete survival time using the Buckley and James's(1979) pseudo random variables, and then proposed the estimator for the conditional survival function. Also, we carried out the simulation studies to compare the performances of the proposed method.

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Credit Prediction Based on Kohonen Network and Survival Analysis (코호넨네트워크와 생존분석을 활용한 신용 예측)

  • Ha, Sung-Ho;Yang, Jeong-Won;Min, Ji-Hong
    • Journal of the Korean Operations Research and Management Science Society
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    • v.34 no.2
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    • pp.35-54
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    • 2009
  • The recent economic crisis not only reduces the profit of department stores but also incurs the significance losses caused by the increasing late-payment rate of credit cards. Under this pressure, the scope of credit prediction needs to be broadened from the simple prediction of whether this customer has a good credit or not to the accurate prediction of how much profit can be gained from this customer. This study classifies the delinquent customers of credit card in a Korean department store into homogeneous clusters. Using this information, this study analyzes the repayment patterns for each cluster and develops the credit prediction system to manage the delinquent customers. The model presented by this study uses Kohonen network, which is one of artificial neural networks of data mining technique, to cluster the credit delinquent customers into clusters. Cox proportional hazard model is also used, which is one of survival analysis used in medical statistics, to analyze the repayment patterns of the delinquent customers in each cluster. The presented model estimates the repayment period of delinquent customers for each cluster and introduces the influencing variables on the repayment pattern prediction. Although there are some differences among clusters, the variables about the purchasing frequency in a month and the average number of installment repayment are the most predictive variables for the repayment pattern. The accuracy of the presented system leaches 97.5%.