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Analysis of Inner Temperature in High Strength Concrete under Standard Temperature-time Curve (표준화재곡선에 의한 고강도 콘크리트 부재의 내부온도 예측)

  • Song, Hun;Lee, Sea-Hyun;Mun, Kyung-Ju;Do, Jeong-Yun;Soh, Yang-Seob
    • Proceedings of the Korea Concrete Institute Conference
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    • 2005.05b
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    • pp.469-472
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    • 2005
  • With all ensuring the fire resistance structure as a method of setting the required cover thickness to fire, the RC is significantly affected from the standpoint of its structural stability that the compressive strength and elastic modulus is reduced by fire. Normally, the degradation of concrete member exposed to fire is largely dependent on the fire scale and fire condition. There is therefore a need to precisely predict the deterioration and fire damage of the exposed member. Thus, this work estimated the temperature distribution inside a member taking into consideration of the thermal properties by means of finite element method(FEM). The estimation results in a little higher prediction value than the experimental value in surface layer and is almost coincident with the experiment as the heating depth increase. From this work it can be known that the simulation application of FEM using the thermal properties of concrete member in high temperature gives rise to the confident prediction in the prediction of temperature distribution.

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New Lung Cancer Panel for High-Throughput Targeted Resequencing

  • Kim, Eun-Hye;Lee, Sunghoon;Park, Jongsun;Lee, Kyusang;Bhak, Jong;Kim, Byung Chul
    • Genomics & Informatics
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    • v.12 no.2
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    • pp.50-57
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    • 2014
  • We present a new next-generation sequencing-based method to identify somatic mutations of lung cancer. It is a comprehensive mutation profiling protocol to detect somatic mutations in 30 genes found frequently in lung adenocarcinoma. The total length of the target regions is 107 kb, and a capture assay was designed to cover 99% of it. This method exhibited about 97% mean coverage at $30{\times}$ sequencing depth and 42% average specificity when sequencing of more than 3.25 Gb was carried out for the normal sample. We discovered 513 variations from targeted exome sequencing of lung cancer cells, which is 3.9-fold higher than in the normal sample. The variations in cancer cells included previously reported somatic mutations in the COSMIC database, such as variations in TP53, KRAS, and STK11 of sample H-23 and in EGFR of sample H-1650, especially with more than $1,000{\times}$ coverage. Among the somatic mutations, up to 91% of single nucleotide polymorphisms from the two cancer samples were validated by DNA microarray-based genotyping. Our results demonstrated the feasibility of high-throughput mutation profiling with lung adenocarcinoma samples, and the profiling method can be used as a robust and effective protocol for somatic variant screening.

A Phenomenological Study on the Information Technology Acceptance of the Korean Baby Boomer Generation

  • Kim, Sohyun;Brady, John Thomas
    • International Journal of Advanced Culture Technology
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    • v.7 no.4
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    • pp.172-186
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    • 2019
  • As ICT technology develops rapidly and social and consumer interactions require more knowledge of the technology, the interest for baby boomers' ICT technology acceptance is increasing as they age. However, previous studies have limitations as they lack a systematic and in-depth understanding of this phenomenon in which the emerging elderly population embraces emerging technology. To overcome this limitation, this study carried out a phenomenological study on baby boomers' ICT technology acceptance. In addition, since existing studies have just simply listed variables or proved the relationship between a few variables, this study aimed to find the relationship between variables by analyzing the data obtained through semi-structured interviews. Through this procedure, it was aimed to construct conceptual model which illustrates the relationships between variables so that understanding the phenomenon of baby boomers' acceptance of ICT technology with a holistic view could be possible. The ten variables suggested by Lee & Coughlin (2015) that cover multiple sides of baby boomers' technology acceptance were used. As a result, we found that there is a sequential relationship between these variables and different agents can be related to each variable in sequence. Also, from an ecological perspective, we analyzed baby boomers and their surroundings to find agents involved in this phenomenon.

Bond Splitting Strength and Behavior of GFRP Reinforcement with Roughened Surface (거친표면 GFRP 보강근의 쪼갬부착파괴강도 및 거동 고찰)

  • Moon, Do-Young
    • Journal of the Korean Society of Hazard Mitigation
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    • v.11 no.2
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    • pp.23-29
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    • 2011
  • In this experimental study, bond splitting strength and behavior were evaluated through pull-out tests. The tests were conducted on a GFRP rebar with roughened surface which was produced by Canadian manufacturer. The used variables in this study were rebar diameter, cover depth and compressive strength of concrete. For each variable, five specimens were made and tested to obtain good results. The bond splitting behavior was investigated from the relationship of pull-out force and slip. The experimental bond splitting strength was compared with the predicted strength obtained from the equations presented by some researchers. The results of the comparison demonstrated that the strength could be predicted well by using the Harajli et al's equation.

Cost Management of Ecotourism Programs: A Case Study of the Community Enterprises in Thailand

  • DUNGTRIPOP, Wilawan;SRISUWAN, Praphada
    • The Journal of Asian Finance, Economics and Business
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    • v.8 no.7
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    • pp.181-193
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    • 2021
  • Thailand's tourism industry contributed to over three trillion baht in 2019. Tourist attractions across Thailand attract tourists around the world with their natural scenery, lifestyles, and cultures, especially in those called "second-tier cities". Community enterprises play a vital role to drive the tourism industry to local areas. However, most community enterprises lack professional accounting knowledge. This research aims to provide guidelines for ecotourism cost management of community enterprises in Thailand. Participatory Action Research (PAR) was employed to investigate the current circumstances of the Banlaem enterprise by using in-depth interviews to identify problems in cost management. Then, the focus and small group meetings were organized to monitor and evaluate solutions. The results reveal that the cost of VIP-Two Days trip was generating the highest net profit and margin, followed by VIP-One Day trip, but net losses were detected on the Students-One Day trip, even though income was greater than the variable costs, revenues didn't cover fixed costs. Thus, accounting knowledge could be a major concern of these enterprises. They should systematically record revenues and expenses, set appropriate labor costs, reduce production costs by using seasonal seafood and make use of vegetables in their gardens, and price products according to their production costs.

Flood Runoff Analysis of Multi-purpose Dam Watersheds in the Han River Basin using a Grid-based Rainfall-Runoff Model (격자기반의 강우유출모형을 통한 한강수계 다목적댐의 홍수유출해석)

  • Park, In-Hyeok;Park, Jin-Hyeog;Hur, Young-Teck
    • Journal of Korean Society on Water Environment
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    • v.27 no.5
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    • pp.587-596
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    • 2011
  • The interest in hydrological modeling has increased significantly recently due to the necessity of watershed management, specifically in regards to lumped models, which are being prosperously utilized because of their relatively uncomplicated algorithms which require less simulation time. However, lumped models require empirical coefficients for hydrological analyses, which do not take into consideration the heterogeneity of site-specific characteristics. To overcome such obstacles, a distributed model was offered as an alternative and the number of researches related to watershed management and distributed models has been steadily increasing in the recent years. Thus, in this study, the feasibility of a grid-based rainfall-runoff model was reviewed using the flood runoff process in the Han River basin, including the ChungjuDam, HoengseongDam and SoyangDam watersheds. Hydrological parameters based on GIS/RS were extracted from basic GIS data such as DEM, land cover, soil map and rainfall depth. The accuracy of the runoff analysis for the model application was evaluated using EFF, NRMSE and QER. The calculation results showed that there was a good agreement with the observed data. Besides the ungauged spatial characteristics in the SoyangDam watershed, EFF showed a good result of 0.859.

A study of minimizing edge chipping of coverglass using MR Polishing (MR Polishing을 이용한 커버글라스의 굽힘강도 향상에 관한 연구)

  • Lee, Jeong-woo;Kim, Ji-Hun;Lim, Dong-Wook;Ha, Seok-Jae
    • Design & Manufacturing
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    • v.16 no.1
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    • pp.50-54
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    • 2022
  • Coverglass of electronic equipments is thinner and slimmer, so the glass must have good bending strength. In these days, the polishing edge of glass is used by solid tool like grinding wheel. But solid tool leave micro crack or edge chipping in edge of glass. MR polishing is an optimal method by polishing edge of glass. MR polishing is used MR fluid that is a liquid tool. MR polishing doesn't leave tool path or residual stress, micro crack and edge chipping unlike grinding wheel polishing. In this paper, the results of grinding and MR polishing were compared and analyzed to improve bending strength by minimizing edge chipping of cover glass. It was derived that the depth and size of cracks have a significant influence on the bending strength of the glass edge. The edges of the glass using MR grinding were analyzed to have a better surface and higher bending strength than the glass using abrasive wheel grinding. It was confirmed that MR polishing had an effect on strength improvement by effectively removing cracks in the specimen.

Treatment of Class II Furcation Involvements in Humans with Bioabsorbable Guided Tissue Regeneration Barriers (2급 치근분지부 병소에서의 생분해성 차폐막의 효과)

  • Lee, Hak-Churl;Han, Seoung-Min;Seol, Yang-Jo;Lee, Chul-Woo;Um, Heung-Sik;Chang, Beom-Suk;Chung, Chong-Pyoung;Han, Soo-Boo
    • Journal of Periodontal and Implant Science
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    • v.29 no.3
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    • pp.539-553
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    • 1999
  • The purpose of this 6-months study was to compare the clinical and radiographic outcomes following guided tissue regeneration treating human mandibular Class II furcation defects with a bioabsorbable BioMesh barrier(test treatment) or a nonabsorbable ePTFE barrier(control treatment). Fourteen defects in 14 patients(mean age 44 years) were treated with BioMesh barriers and ten defects in 10 patients(mean age 48 years) with ePTFE barriers. After initial therapy, a GTR procedure was done. Following flap elevation, root planing, and removal of granulation tissue, each device was adjusted to cover the furcation defect. The flaps were repositioned and sutured to complete coverage of the barriers. A second surgical procedure was performed at control sites after 4 to 6 weeks to remove the nonresorbable barrier. Radiographic and clinical examinations(plaque index, gingival index, tooth mobility, gingival margin position, pocket depth, clinical attachment level) were carried out under standardized conditions immediately before and 6 months after surgery. Furthermore, digital subtraction radiography was carried out. All areas healed uneventfully. Surgical treatment resulted in clinically and statistically equivalent changes when comparisons were made between test and control treatments. Changes in plaque index were 0.7 for test and 0.4 for control treatments; changes in gingival index were 0.9 and 0.5. In both group gingival margin position and pocket depth reduction was 1.0mm and 3.0mm; clinical attachment level gain was 1.9mm. There were no changes in tooth mobility and the bone in radiographic evaluation. No significant(p${\leq }$0.05) difference between the two membranes could be detected with regard to plaque index, gingival index, gingival margin position, pocket depth, and clinical attachment level. In conclusion, a bioabsorbable BioMesh membrane is effective in human mandibular Class II furcation defects and a longer period study is needed to fully evaluate the outcomes.

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Measuring System of Visual Evoked Potential (VEP) in Mice using BioPAC Modules (BioPAC 모듈을 이용한 마우스 시각유발전위 측정 시스템 확립)

  • Lee, Wang Woo;Ahn, Jung Ryul;Goo, Yong Sook
    • Journal of Biomedical Engineering Research
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    • v.38 no.1
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    • pp.16-24
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    • 2017
  • For the development of feasible retinal prosthesis, one of the important elements is acquiring proper judging tool if electrical stimulus leads to patient's visual perception. If evoked potential to electrical stimulus is recorded in primary visual (V1) cortex, it means that the stimulus effectively evokes visual perception. Therefore, in this study, we established VEP recording system on V1 cortex using BioPAC modules as the judging tool. And the measuring system was evaluated by recording VEP of mice. After anesthesia, normal mice (C57BL/6J strain; n = 6) were secured to stereotaxic apparatus (Harvard Apparatus, USA). For the recording of VEP, the stainless steel needle electrode (impedance: $2-5k{\Omega}$) was positioned on the surface of the cortex through the burr hole at 2.5 mm lateral and 4.6 mm caudal to bregma. DA 100C and EEG 100C BioPAC modules were used for the trigger signal and VEP recording, respectively. When left eye was blocked by black cover and right eye was stimulated by flash light using HMsERG (RetVet Corp, USA), VEP response at left V1 cortex was detected, but there was no response at right V1 cortex. Amplitudes and latencies of P2, N3 peaks of VEP recording varied according to the depths of the electrodes on V1 cortex. From the surface upto $600{\mu}m$ depth, amplitudes of P2 and N3 increased, while deeper than $600{\mu}m$, those amplitudes decreased. The deeper the insertion depth of the electrode, the latency of N1 peaks tends to be delayed. However, there was no statistically significant difference among the latencies of P2 and N3 peaks (P > 0.05, ANOVA). Our VEP recording data such as the insertion depth and the latency and amplitudes of peaks might be used as guidelines for electrically-evoked potential (EEP) recording experiment in near future.

Open Channel Characteristics on Different Land Cover for Neponset River, Boston, MA (상이한 토지이용에서 나타나는 하천의 특성에 관한 연구 : 메사추세츠 보스턴의 네폰셋강의 사례연구)

  • Lee, Ja-Won
    • Journal of the Korean association of regional geographers
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    • v.16 no.2
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    • pp.100-109
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    • 2010
  • The study examines two different sites to analyze the difference of stream channel profile between two different landuse areas on Neponset River, Boston, MA. Landuse represents the current status of land in terms of human, agricultural or forest, industry and environmental activity types. According to the previous research, forest and urban area are significantly distinguished in chemical characteristic, shape and bed load of the stream. On the chosen sites, I look at the cross-section profile, the slope, velocity, and roughness of the channels. With the data collected at the site I determined the value for the channel bed material using Manning's equation, and compared with the result of HEC-RAS model with the cross-section profile data I measured. In the forest area, water surface elevation and bed material obtained through Manning's equation are very close to HEC-RAS model result. However, in the resident area the Manning's 'n' value calculated much higher than assumption which was considered as cobble whose 'n' value is 0.03-0.06. The difference could be caused by unusual steep elevation on the site and the dam present down further. With the steep elevation upside of dam, there is critical-depth condition occurs. The difference of Manning's 'n' value reflects the difference of depth. HEC-RAS model was run to analyze the difference and the result shows that depth is 0.36 much less than 0.688 what I computed when the Manning's n value is 0.03(cobble) instead of the result of the study (0.13292). Beside, dam is a major source of fragmentation and degradation of stream, and it's possibly inferred upstream water levels are increased and stream velocity is decreased. This study is meaningful for introduction of HEC-RAS in geography field to analyze different sites with channel bed material, and it is going to be used more actively to manage river and river side.

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