• 한국구조물진단유지관리공학회 논문집
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• 제13권6호통권58호
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• pp.192-203
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• 2009

본 연구는 경부고속철도(대구~부산) 도심통과 노반신설 공사중 기존 부산지하철 1호선 및 부산지하철 2호선 구간에 대한 안정성에 관한 연구로서 현장조사를 실시하여 대상시설물의 외관상태, 품질상태 및 내구성능 등을 평가하고 MIDAS/GTS를 이용한 수치해석을 통해 대상시설물 및 본선터널의 안정성을 검토하는데 그 목적이 있다. 지하수위 하에서 터널이 시공되는 기본 메카니즘과 3차원 유한요소해석 응력-간극수압 연계해석을 수행한 후 라이닝 작용하중, 막장안정성, 지표침하 등 지하수와 터널굴착의 상호관계를 고찰하였다. 수치해석의 결과 1, 2호선의 최대침하, 부등침하, 라이닝응력 등은 허용치 이내이며 손상 정도는 무시할 수 있는 정도의 경미한 것으로 나타나고 있다. 그러나 실제 터널 시공시 막장거동을 최소화하기 위하여 필요시 Pre-Grouting을 시행하여 터널 굴착시 터널내 유출수를 최소화하는 것이 필요할 것으로 판단된다.

• Biomolecules & Therapeutics
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• 제15권3호
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• pp.150-155
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• 2007

In the present study, we have tested the effect of dioleoyl phosphatidic acid (PA) on intracellular $Ca_{2+}$ concentration ($[Ca^{2+}]_{i}$) in two human colon cancer cell lines (HCT116 and HT29). PA and lysophosphatidic acid (LPA), a bioactive lysolipid, increased $[Ca^{2+}]_{i}$ in both HCT116 and HT29 cell lines. Increases of $[Ca^{2+}]_{i}$ by PA and LPA were more robust in HCT116 cells than in HT29 cells. A specific inhibitor of phospholipase C (U73122), however, was not inhibitory to the cell responses. Pertussis toxin, a specific inhibitor of $G_{i/o}$ type G proteins, however, had an inhibitory effect on the responses except for an LPA-induced one in HT29 cells. Ruthenium red, an inhibitor of the ryanodine receptor, was not inhibitory on the responses, however, 2-APB, a specific inhibitor of inositol 1,4,5-trisphosphate receptor, completely inhibited both lipid-induced $Ca^{2+}$ increases in both cell types. Furthermore, by using Ki16425 and VPC32183, two structurally dissimilar specific antagonists for $LPA_{1}/LPA_{3}$ receptors, an involvement of endogenous LPA receptors in the $Ca^{2+}$ responses was observed. Ki16425 completely inhibited the responses but the susceptibility to VPC32183 was different to PA and LPA in the two cell types. Expression levels of five LPA receptors in the HCT116 and HT29 cells were also assessed. Our data support the notion that PA could increase $[Ca^{2+}]_{i}$ in human colon cancer cells, probably via endogenous LPA receptors, G proteins and $IP_{3}$ receptors, thereby suggesting a role of PA as an intercellular lipid mediator.

• Journal of electromagnetic engineering and science
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• 제10권1호
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• pp.28-34
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• 2010

This paper introduces a new U.S. ultra-wideband(UWB: 3.1~10.6 GHz) 1:2 power divider based on a single section Wilkinson type configuration. The divider provides very flat in-band power splitting, high isolation, low insertion loss, sharp roll-off bandpass filtering, and DC blocking characteristics. The circuit consists of a $\lambda$/4 Y resonator, three capacitively coupled $\lambda$/2 short-circuited lines, and a resistor between the two output ports. The circuit structure was simulated with ADS and HFSS, and realized with low-temperature co-fired ceramic(LTCC) green tape, which has a dielectric constant of 7.8. $|S_{11}|$ better than 10 dB, $|S_{21}|$ and $|S_{31}|$ less than 3.2 dB, with both $|S_{22}|$ and $|S_{32}|$ measured as better than 12 dB for the whole UWB band. Measurement results agree closely with HFSS simulation results. The power divider has a compact size of $4\times9\times0.6mm^3$.

• JSTS:Journal of Semiconductor Technology and Science
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• 제14권5호
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• pp.649-657
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• 2014

In this study, the effects of the frequency-dependent characteristics of through-silicon vias (TSVs) on the performance of 3D ICs are examined by evaluating a typical interconnection structure, which is composed of 32-nm CMOS inverter drivers and receivers connected through TSVs. The frequency-domain model of TSVs is extracted in S-parameter from a 3D electromagnetic (EM) method, where the dimensional variation effect of TSVs can be accurately considered for a comprehensive parameter sweep simulation. A parametric analysis shows that the propagation delay increases with the diameter and height of the TSVs but decreases with the pitch and liner thickness. We also investigate the crosstalk effect between TSVs by testing different signaling conditions. From the simulations, the worst signal integrity is observed when the signal experiences a simultaneously coupled transition in the opposite direction from the aggressor lines. Simulation results for nine-TSV bundles having regular and staggered patterns reveal that the proposed method can characterize TSV-based 3D interconnections of any dimensions and patterns.

• 한국전자파학회논문지
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• 제16권7호
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• pp.661-670
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• 2005

본 논문에서는 $2\~6$ Hz의 광대역에서 -3 dB 결합 특성과 $90^{\circ}$ 위상차를 제공하는 마이크로스트립 하이브리드를 설계하였다. 3-단 결합기 구조를 가지며, 양 측면 단은 대칭 가장자리 결합 선로로 구현되는 반면에, 가운데 단은 수직으로 장착된 평면 회로로 구성된다. 특히 수직 장착된 평면 회로는 밀 결합 특성을 얻기 위해 일부 접지면이 제거된 형태를 갖는다. 본 하이브리드는 마이크로스트립 구조이기 때문에 제작이 용이하고, 수직 장착 기판을 특성 적정화의 조정점으로 이용함으로써 양호한 튜닝 유연성을 갖는다. 무엇보다도 제안한 하이브리드는 구조와 제작의 단순성에 비해 만족할만한 성능을 제공한다.

• Journal of Microbiology
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• 제44권1호
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• pp.42-49
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• 2006

In this study, we describe our newly-developed sensitive two-stage PCR procedure for the detection of 13 common mycoplasmal contaminants (M. arthritidis, M. bovis, M. fermentans, M. genitalium, M. hominis, M. hyorhinis, M. neurolyticum, M. orale, M. pirum, M. pneumoniae, M. pulmonis, M. salivarium, U. urealyticum). For primary amplification, the DNA regions encompassing the 16S and 23S rRNA genes of 13 species were targeted using general mycoplasma primers. The primary PCR products were then subjected to secondary nested PCR, using two different primer pair sets, designed via the multiple alignment of nucleotide sequences obtained from the 13 mycoplasmal species. The nested PCR, which generated DNA fragments of 165-353 bp, was found to be able to detect 1-2 copies of the target DNA, and evidenced no cross-reactivity with the generated DNA of related microorganisms or of human cell lines, thereby confirming the sensitivity and specificity of the primers used. The identification of contaminated species was' achieved via the performance of restriction fragment length polymorphism (RFLP) coupled with Sau3AI digestion. The results obtained in this study furnish evidence suggesting that the employed assay system constitutes an effective tool for the disagnosis of mycoplasmal contamination in cell culture systems.

• Structural Engineering and Mechanics
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• 제61권6호
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• pp.785-794
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• 2017

This paper is concerned with the comparative numerical and experimental study on the natural behavior and the motion responses of a 1/75 moored scale model of a 2.5 MW spar-type floating offshore wind turbine subject to 1-D regular wave. Heave, pitch and surge motions and the mooring tensions are investigated and compared by numerical and experimental methods. The upper part of wind turbine which is composed of three rotor blades, hub and nacelle is modeled as a lumped mass and three mooring lines are pre-tensioned by means of linear springs. The numerical simulations are carried out by a coupled FEM-cable dynamics code, while the experiments are performed in a wave tank equipped with the specially-designed vision and data acquisition system. Using the both methods, the natural behavior and the motion responses in RAOs are compared and parametrically investigated to the fairlead position, the spring constant and the location of mass center of platform. It is confirmed, from the comparison, that both methods show a good agreement for all the test cases. And, it is observed that the mooring tension is influenced by all three parameters but the platform motion is dominated by the location of mass center. In addition, from the sensitivity analysis of RAOs, the coupling characteristic of platform motions and the sensitivities to the mooring parameters are investigated.

• Progress in Superconductivity
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• 제6권1호
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• pp.19-23
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• 2004

YBCO do superconducting quantum interference device (SQUID) magnetometers based on bicrystal Josephson junctions on 10 mm ${\times}$ 10 mm $SrTiO_3$ substrates have been fabricated. The pickup coil of the device was designed to have 16 parallel loops with 50-fm-wide lines. We could obtain optimised direct coupled YBCO SQUID magnetometer design with field sensitivity $B_{N}$ $\Phi$/ of $4.5 nT/\Phi_{0}$ and magnetic field noise $B_{N}$ of about $22 fT/Hz^{1}$2/ with an I/f corner frequency of 2 Hz measured inside a magnetically shielded room. Preliminary results of magnetocardiograph measurement using the HTS SQUID magnetometers show signal to noise ratio of about 110, which is comparable to the quality of a commercial MCG system based on Nb-SQUIDs.

• 한국전자통신학회논문지
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• 제2권4호
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• pp.199-202
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• 2007

본 논문에서는 UHF 대역(860~960 MHz의 수동 RFID 태그 안테나 제안하여 해석하였다. 제안한 안테나는 루프구조에 의한 UHF 대역 초소형 수동 RFID 태그 안테나이다. 제안한 안테나는 단일 평면 구조 형태로 인쇄 기판에 손쉽게 인쇄할 수 있어 생산비 절감을 통한 대량 생산이 용이하며, Pareto 유전자 알고리즘과 IE3D 시뮬레이션 툴로 최적화하여 안테나의 크기를 소형화 하였다. 최적화 한 RFID 태그 안테나의 성능을 검증하기 위하여 몇 개의 표본 안테나를 제작하고 반사 손실, 복사 효율, 복사 패턴 등을 측정하였다. 상용태그 와 고정형 리더 시스템을 이용하여 제작된 태그 안테나의 인식 거리를 측정하였고, 약 1~3 m의 인식거리를 가지는 것을 확인하였다.

• 대한전자공학회논문지TC
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• 제37권6호
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• pp.396-396
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• 2000

두 개의 마이크로 스트립 선로를 이용하여 결합한 유전체 공진기를 유한 차분 시간 영역(FDTD)법을 적용하여 3차원 해석을 하였다. 유전체 공진기의 표면은 곡면으로서, Noriaki model을 이용하여 정확하게 모델링 하였다. 일반적인 FFT에 의해 106.46 MHz의 주파수 해상도를 얻었지만 공진 주파수를 결정할 수가 없다. 따라서 1.00 MHz의 높은 주파수 분해능을 갖기 위해서 Pad 근사법과 Stoer-Bulirsch법을 적용하고 측정치와 비교하였다. 그 결과 Pad 근사법을 통하여 매우 정확한 공진주파수를 얻었다. 그리고 정현파를 인가하여 전자계 분포를 도시하였으며, 공진 모드가 $TE_{01{\delta}}$ 모드임을 알 수 있었다.