• Title/Summary/Keyword: Coupled channel analysis

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Consensus channelome of dinoflagellates revealed by transcriptomic analysis sheds light on their physiology

  • Pozdnyakov, Ilya;Matantseva, Olga;Skarlato, Sergei
    • ALGAE
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    • v.36 no.4
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    • pp.315-326
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    • 2021
  • Ion channels are membrane protein complexes mediating passive ion flux across the cell membranes. Every organism has a certain set of ion channels that define its physiology. Dinoflagellates are ecologically important microorganisms characterized by effective physiological adaptability, which backs up their massive proliferations that often result in harmful blooms (red tides). In this study, we used a bioinformatics approach to identify homologs of known ion channels that belong to 36 ion channel families. We demonstrated that the versatility of the dinoflagellate physiology is underpinned by a high diversity of ion channels including homologs of animal and plant proteins, as well as channels unique to protists. The analysis of 27 transcriptomes allowed reconstructing a consensus ion channel repertoire (channelome) of dinoflagellates including the members of 31 ion channel families: inwardly-rectifying potassium channels, two-pore domain potassium channels, voltage-gated potassium channels (Kv), tandem Kv, cyclic nucleotide-binding domain-containing channels (CNBD), tandem CNBD, eukaryotic ionotropic glutamate receptors, large-conductance calcium-activated potassium channels, intermediate/small-conductance calcium-activated potassium channels, eukaryotic single-domain voltage-gated cation channels, transient receptor potential channels, two-pore domain calcium channels, four-domain voltage-gated cation channels, cation and anion Cys-loop receptors, small-conductivity mechanosensitive channels, large-conductivity mechanosensitive channels, voltage-gated proton channels, inositole-1,4,5-trisphosphate receptors, slow anion channels, aluminum-activated malate transporters and quick anion channels, mitochondrial calcium uniporters, voltage-dependent anion channels, vesicular chloride channels, ionotropic purinergic receptors, animal volage-insensitive cation channels, channelrhodopsins, bestrophins, voltage-gated chloride channels H+/Cl- exchangers, plant calcium-permeable mechanosensitive channels, and trimeric intracellular cation channels. Overall, dinoflagellates represent cells able to respond to physical and chemical stimuli utilizing a wide range of G-protein coupled receptors- and Ca2+-dependent signaling pathways. The applied approach not only shed light on the ion channel set in dinoflagellates, but also provided the information on possible molecular mechanisms underlying vital cellular processes dependent on the ion transport.

Steady- and Transient-State Analyses of Fully Ceramic Microencapsulated Fuel with Randomly Dispersed Tristructural Isotropic Particles via Two-Temperature Homogenized Model-II: Applications by Coupling with COREDAX

  • Lee, Yoonhee;Cho, Bumhee;Cho, Nam Zin
    • Nuclear Engineering and Technology
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    • v.48 no.3
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    • pp.660-672
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    • 2016
  • In Part I of this paper, the two-temperature homogenized model for the fully ceramic microencapsulated fuel, in which tristructural isotropic particles are randomly dispersed in a fine lattice stochastic structure, was discussed. In this model, the fuel-kernel and silicon carbide matrix temperatures are distinguished. Moreover, the obtained temperature profiles are more realistic than those obtained using other models. Using the temperature-dependent thermal conductivities of uranium nitride and the silicon carbide matrix, temperature-dependent homogenized parameters were obtained. In Part II of the paper, coupled with the COREDAX code, a reactor core loaded by fully ceramic microencapsulated fuel in which tristructural isotropic particles are randomly dispersed in the fine lattice stochastic structure is analyzed via a two-temperature homogenized model at steady and transient states. The results are compared with those from harmonic- and volumetric-average thermal conductivity models; i.e., we compare $k_{eff}$ eigenvalues, power distributions, and temperature profiles in the hottest single channel at a steady state. At transient states, we compare total power, average energy deposition, and maximum temperatures in the hottest single channel obtained by the different thermal analysis models. The different thermal analysis models and the availability of fuel-kernel temperatures in the two-temperature homogenized model for Doppler temperature feedback lead to significant differences.

Entropy analysis in a cilia transport of nanofluid under the influence of magnetic field

  • Abrar, Muhammad N.;Haq, Rizwan Ul;Awais, Muhammad;Rashid, Irfan
    • Nuclear Engineering and Technology
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    • v.49 no.8
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    • pp.1680-1688
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    • 2017
  • In this study, analysis is performed on entropy generation during cilia transport of water based titanium dioxide nanoparticles in the presence of viscous dissipation. Moreover, thermal heat flux is considered at the surface of a channel with ciliated walls. Mathematical formulation is constructed in the form of nonlinear partial differential equations. Making use of suitable variables, the set of partial differential equations is reduced to coupled nonlinear ordinary differential equations. Closed form exact solutions are obtained for velocity, temperature, and pressure gradient. Graphical illustrations for emerging flow parameters, such as Hartmann number (Ha), Brinkmann number (Br), radiation parameter (Rn), and flow rate, have been prepared in order to capture the physical behavior of these parameters. The main goal (i.e., the minimizing of entropy generation) of the second law of thermodynamics can be achieved by decreasing the magnitude of Br, Ha and ${\Lambda}$ parameters.

Analysis of Dielectric Rectangular Waveguide and Directional Coupler with Step Index Profile by the Modified Effective Index Method (수정된 실효 굴절율법에 의한 계단형 굴절률 분포를 갖는 광도파로와 방향성 결합기의 해석)

  • Kim, Chang Min;Jung, Byung Gi;Lee, Choang Woong
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.23 no.4
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    • pp.522-528
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    • 1986
  • Based on the modified effective index method, analysis of dielectric rectangular waveguides and directional couplers are presented. Aside from the effective index concept of channel region, the equivalent index concept of cladding region is proposed. The error problem of eigenvalues, which has been experienced when the effective index method is used, is improved. Our approxiamtions give similar accuracy when compared with the results of other regorous approxiamtion techiniques. The advantage of the modified effective index methods is utilized by replacing the directional coupler with the equivalent slab guides, and the coupling constant is calculated by the coupled mode theory. The effectiveness of the equivalent index concept is positively confirmed.

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Numerical Analysis of Rainfall Induced Landslide Dam Formation

  • Do, Xuan Khanh;Regmi, Ram Krishna;Jung, Kwansue
    • Proceedings of the Korea Water Resources Association Conference
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    • 2015.05a
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    • pp.245-245
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    • 2015
  • In the recent years, due to long-lasting heavy rainfall events, a large number of landslides have been observed in the mountainous area of the world. Such landslides can also form a dam as it blocks the course of a river, which may burst and cause a catastrophic flood. Numerical analysis of landslide dam formation is rarely available, while laboratory experimental studies often use assumed shape to analyze the landslide dam failure and flood hydraulics in downstream. In this study, both experimental and numerical studies have been carried out to investigate the formation of landslide dam. Two case laboratory experiments were conducted in two flumes simultaneously. The first flume (2.0 m 0.6 m 0.5 m) was set at $22^{\circ}$ and $27^{\circ}$ slope to generate the landslide using rainfall intensity of 70.0 mm/hr. On the other hand, the second flume (1.5 m 0.25 m 0.3 m) was set perpendicularly at the downstream end of the first flume to receive the landslide mass forming landslide dam. The formation of landslide dam was observed at $15^{\circ}$ slope of the second flume. The whole processes including the landslide initiation and movement of the landslide mass into the second channel was captured by three digital cameras. In numerical analysis, a two-dimensional (2D) seepage flow model, a 2D slope stability model (Spencer method) and a 2D landslide dam-geometry evaluation model were coupled as a single unit. This developed model can determine the landslide occurrence time, the failure mass and the geometry of landslide dam deposited in the second channel. The data obtained from numerical simulation results has good agreement with the experimental measurements.

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Development of a System Analysis Code, SSC-K, for Inherent Safety Evaluation of The Korea Advanced Liquid Metal Reactor

  • Kwon, Young-Min;Lee, Yong-Bum;Chang, Won-Pyo;Dohee Hahn;Kim, Kyung-Doo
    • Nuclear Engineering and Technology
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    • v.33 no.2
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    • pp.209-224
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    • 2001
  • The SSC-K system analysis code is under development at the Korea Atomic Energy Research Institute (KAERI) as a part of the KALIMER project. The SSC-K code is being used as the principal tool for analyzing a variety of off-normal conditions or accidents of the preliminary KALIMER design. The SSC-K code features a multiple-channel core representation coupled with a point kinetics model with reactivity feedback. It provides a detailed, one-dimensional thermal-hydraulic simulation of the primary and secondary sodium coolant circuits, as well as the balance-of-plant steam/water circuit. Recently a two-dimensional hot pool model was incorporated into SSC-K for analysis of thermal stratification phenomena in the hot pool. In addition, SSC-K contains detailed models for the passive decay heat removal system and a generalized plant control system. The SSC-K code has also been applied to the computational engine for an interactive simulation of the KALIMER plant. This paper presents an overview of the recent activities concerned with SSC-K code model development This paper focuses on both descriptions of the newly adopted thermal hydraulic and neutronic models, and applications to KALIMER analyses for typical anticipated transients without scram.

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Investigation of the Conjugate Heat Transfer and Wall Thermal Boundary Conditions (복합열전달과 열경계조건에 관한 연구)

  • Chang, Byong Hoon
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.23 no.1
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    • pp.33-42
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    • 1999
  • The effects of wan thermal boundary condition were investigated for a uniform wall temperature, a uniform wall heat flux, and for coupled heat conduction In the channel wall with transverse rectangular ribs. Numerical investigations for steady laminar flow show behavior similar to that observed experimentally in the separated flow region for flow over a cylinder. Conjugate heat transfer with a low solid-fluid thermal conductivity ratio does not lead to the same results as for the uniform heat flux boundary condition, and heat transfer reversal is found on the back sides of the ribs.

Coupled Mode Analysis of Phase-Locked CSP Laser Arrays (위상이 고착된 CSP 레이저 어레이의 결합 모우드 해석)

  • 吳煥述
    • Journal of the Korean Institute of Telematics and Electronics
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    • v.24 no.1
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    • pp.133-139
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    • 1987
  • A phase-locked Channel-Substrate-Planar(CSP) laser arrays is described. Arrays of emitters with weak coupling are operated in a set of discrete modes determined by the number and spacing of the emitters. The interactions between emitters lead to a splitting of the wave-length and gain which are calculated from the coupling strength. Phase-locked arrays has exhibited to CW output-power as high as 80 m W and the highest order mode will have preferred oscillation. A strong hole burning is occurred at p=30m W. The most stable lasing mode is occurred at element spacing S=3.5\ulcornerm and there is no coupling at S>7 \ulcornerm.

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Study on the Effect of Performance Factors on the Evaporator Using Liquid Desiccant Falling Flim for Dehumidification (습식건조제 이용 제습에서의 증발기 성능인자 영향 연구)

  • Park, M.S.
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.7 no.3
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    • pp.512-520
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    • 1995
  • This study investigates the simultanceous heat and mass transfer between a falling desiccant film and air in cross flow at the interface. The application of this work is the optimization of falling film evaporators for use in potential hybrid air conditioning systems. The specific geometry considered is liquid TEG films falling along the vertical cooled surfaces of a channel with air in cross flow. The equations to describe the coupled heat and mass transfer between a falling desiccant film and air in cross flow for a falling film evaporator have been presented and solved numerically. The effects of important design and operating variables on the evaporator performance predicted by the parametric numerical analysis and suggestions for performance improvements of the evaporator are presented.

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Effects of ring number and baffled-ring distances on ultrafiltration in the tubular membrane inserted concentrically with a ring rod

  • Yeh, Ho-Ming;Ho, Chii-Dong;Li, Cha-Hsin
    • Membrane and Water Treatment
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    • v.3 no.1
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    • pp.51-62
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    • 2012
  • The permeate flux declination along an ultrafilter membrane is due mainly to the concentration-polarization resistance increment and the decline in transmembrane pressure. It was found in previous works that the concentration polarization resistance could be reduced in a ring-rod tubular membrane ultrafilter using the turbulent behavior. In the present study, the performance was further improved by properly and gradually decreasing the baffled-ring distance along the cross-flow channel coupled with properly adjusting the number of baffled rings. This theoretical analysis is based on the mass and momentum balances as well as the application of the resistance-in-series model. The correlation predictions are confirmed with the experimental results for dextran T500 aqueous solution ultrafiltration.