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Genetic Studies on Faecal Egg Counts and Packed Cell Volume Following Natural Haemonchus contortus Infection and Their Relationships with Liveweight in Muzaffarnagari Sheep

  • Yadav, N.K.;Mandal, Ajoy;Sharma, D.K.;Rout, P.K.;Roy, R.
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.11
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    • pp.1524-1528
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    • 2006
  • A total of 437 animals, comprising lambs aged between 3 and 12 months and adults of either sex of Muzaffarnagari sheep maintained at the Central Institute for Research on Goats, Makhdoom, Farah, Mathura, India were screened to assess the prevalence of Haemonchus contortus infection following natural infection and to identify the various factors affecting faecal egg count (FEC) and packed cell volume (PCV) of ewes and their genetic control. The relationships between FEC, PCV and body weight were also estimated. The prevalence rate for H. contortus infection in the flock under study was 15.7% indicating much lower occurrence of worm infection in lambs up to one year of age. On the other hand, a large proportion i.e., 67.7% of sheep was refractive to natural H. contortus infection. The random effect of sire significantly contributed (p<0.01) variation in log-transformed FEC (LFEC) of ewes. The season of birth had a significant (p<0.01) effect on LFEC of ewes. The lactating ewes had significantly (p<0.01) higher faecal egg counts compared to dry and pregnant ewes. The linear regression effects of the age of ewes on LFEC of animals were significant (p<0.01) in the present study. The heritabilities of LFEC, PCV and body weights of ewes during the course of infection were moderate to high in magnitude and ranged from 0.24 to 0.47. The LFEC of ewes was significantly (p<0.05) and negatively correlated with PCV at both genetic and phenotypic level. The genetic and phenotypic relationships between LFEC and body weights of ewes were -0.26 and -0.06 for this breed. The genetic correlation of PCV and body weight of ewes was positive and high (0.58) and statistically significant (p<0.05) but it was negatively correlated (-0.01) with body weight at the phenotypic level.

The Hematologic Study on Cerebral Infarction (뇌경색환자의 혈액학적 소견 연구)

  • Kim, Yoon-Sik
    • Journal of Haehwa Medicine
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    • v.12 no.2
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    • pp.1-9
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    • 2004
  • 1. Purpose Stroke is the most frequent cause of mortality and morbidity rate in Korea with coronary heart disease and cancer. The ischemic type of stroke is increasing tendency. The purpose of this studies is to examine the hematologic difference between cb infarction patients and Korean normal adults. 2. Method The study group consisted of neurologically confirmd 50 cb-infarction patients as the case group and 278 patients as control group that they had no significant result by CT through early examination of stroke in Cheonan oriental hospital of Daejeon university. We tested and compared RBC, hemoglobin, hematocrit, WBC, PT, PTT, total protein, albumin, total bilirubin, direct bilirubin, GOT GPT, $\gamma$-GTP, total cholesterol, triglyceride, HDL-C, glucose, BUN, creatinine, Na, K in the both group. 3. Result In the sample group(cb infarction group), there were many patients with low RBC count but no significant and with low hemoglobin, hematocrit(p<0.05). Thereas, increased WBC count and delayed PTT were showed respectively 20%, 36% in patient group, 7.9%, 4.7% in normal group(p<0.05). Comparing the LFT between cb infarction patients and normal adults, we founded significant cases with low HDL-C level, high glucose level, low potassium level in patient group(p<0.05). But the percentage of high total cholesterol level and triglyceride level were 18%, 29%(norma1 group), 20%, 28%(cb infarction group) respectively, there were no significant difference. 4. Conclusion In this study, we demonstrated that low HDL-C level and high glucose level is one of important risk factor of cb infarction. Also prospective studies are needed to evaluate many risk factor(hemoglobin, hematocrit, WBC, cholesterol, triglyceride, K, etc) of cb infarction.

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Effect of Herbal-acupuncture with Chaenomelis Fructus Solution at the Joksamni($ST_{36}$) of Mice with Collagen-induced Aarthritis (목과(木瓜) 약침(藥鍼)이 Collagen-induced Arthritis 억제 및 면역조절에 미치는 영향)

  • Shin, Dong-Soo;Kim, Young-Il;Lee, Hyun
    • Journal of Acupuncture Research
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    • v.24 no.3
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    • pp.127-143
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    • 2007
  • Objectives : The purpose of this study was to observe the effects of Chaenomelis Fructus herbal-acupuncture solution (ChF-HAS) at the Joksamni ($ST_{36}$) on arthritis induced by Collagen II in mice. Methods : The author performed several experimental items. The severity of arthritis, changes of mouse weight, size of the spleen and the degree of stenosis, changes of cytokine level, IgG, IgM and anti-collagen II, changes of immunocyte count, histological changes of the CIA mouse joint were analyzed and the conclusions are as follows. Results: 1. In the ChF-HA, the arthritis index, the incidence of arthritis, the degree of joint edema was significantly decreased. 2. In the ChF-HA, weight, spleen size and stenosis rate was low and maintained as the normal group was. 3. In the ChF-HA, cytokine level, IgG, IgM and anti-collagen II were significantly decreased. 4. In the ChF-HA, on changes of immunocyte count were maintained to the levels of normal group. 5. In histological changes of the CIA mouse joint, the cartilage destruction and synovial cell proliferation were decreased. Conclusions: These results suggest that ChF-HA at the $ST_{36}$ has an important role to control the immune reactions and suppress inflammatory response on the collagen induced rheumatoid arthritis. This study can be a significant supporting evidence that ChF-HA is chosen to be the principal therapy for clinical practice of the rheumatoid arthritis in the future.

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A Study on the Relationship between Body Composition Analysis and CBC in University Students (대학생의 체성분분석과 혈구산정검사의 관계연구)

  • Jo, Yoon-kyung;Yoon, Joon;Cho, Young-KuK;Sung, Hyun-Ho
    • Korean Journal of Clinical Laboratory Science
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    • v.48 no.3
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    • pp.269-274
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    • 2016
  • The tendency of students to become adults in the future to improve the country's public health policy and to determine the socio-economic development of the research is very important. The objectives of this study were to examine the changes in body weight, body mass index (BMI), body composition, and complete blood cell count in a group of male and female university students. Among the body compositions, height, weight, BMI, muscle volume, basal metabolic rate, red blood cells, hemoglobin, and hematocrit showed a correlation between the amount shown both had statistical significance (p<0.01). In particular, platelets showed a rather different result from fat and body fat percentage, and were positively correlated with waist-hip ratio points (p<0.01). This study may be useful as it provides the basic data necessary for students of healthcare. Therefore, developing a sustainable management system of healthcare on a national level for university students is very important.

An Efficient Bit Loading Algorithm for OFDM-based Wireless LAN systems and Hardware Architecture Design (OFDM 기반의 무선 LAN 시스템을 위한 효율적인 비트 로딩 알고리즘 및 하드웨어 구조 설계)

  • 강희윤;손병직;정윤호;김근회;김재석
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.41 no.5
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    • pp.153-160
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    • 2004
  • In this paper, we propose an efficient bit loading algorithm for IEEE 802.11a wireless LAN systems. While a conventional bit loading algorithm uses the SNR value of each subcarrier, it is very difficult to estimate the exact SNR value in wireless LAN systems due to randomness of AWGN. Therefore, in order to solve this problem our proposed algorithm uses the channel frequency response instead of the SNR of each subcarrier. Through simulation results, we can obtain the performance gain of 3.5∼8㏈ at PER of 10-2 with the proposed bit loading algorithm while the conventional one obtains the performance gain of 0.5∼5㏈ at the same conditions. Also, the increased data rate can be confirmed 63Mbps. After the logic synthesis using 0.3${\mu}{\textrm}{m}$ CMOS technology, the logic gate count for the processor with proposed algorithm can be reduced by 34% in comparison with the conventional one.

The Change of Salivary and Oral Bacteria Amount by Composition of SLS Contents of Toothpaste (세치제내 SLS함유에 따른 타액과 세균변화)

  • Shim, Youn-Su;Jeong, Mi-Ae;Jeong, Sang-Hee
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.9
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    • pp.3341-3346
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    • 2010
  • Dentifrices comtaining SLS of 2.2% and 0.0% were applied to 60 subjects for 4 weeks in this study. Dentifrice is used for salivary and oral bacteria amount change according to its SLS contents in toothpaste. The results were as follows. Anaysis of LSL contents befor and after the after experiment in salivary and bacterial count oral cavity didn't show significant difference in time interval. There was no correlation between salivary flow rate and bacterial count in the oral cavity according to content of SLS. Dentifrice of 2.2% content satisfied the subjects much more than that of 0.0% content(p<0.001).

Clinical Value of Procalcitonin in Patients with Spinal Infection

  • Jeong, Deok-Ki;Lee, Hyun-Woo;Kwon, Young-Min
    • Journal of Korean Neurosurgical Society
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    • v.58 no.3
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    • pp.271-275
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    • 2015
  • Objective : This study was designed to evaluation the diagnostic value of procalcitonin (PCT) in patients with spinal infection, compare to the classical biomarkers such as C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), white blood cell (WBC) count. Methods : All patients who were diagnosed as a spinal infection between January, 2013 and July, 2014 were included in this study. Serum PCT, CRP, ESR, and WBC count were checked at initial hospital visit and once a week serially until they were discharged. Patient's medical history, causes and pathogens of spinal infection were reviewed. Results : Total 34 (16 men, 18 women) patients were included in this study. Mean age of the patients was 65.6 year-old. Causes of spinal infection were pain block procedure (14, 41.2%) and post-operation (5, 14.7%). Out of 25 patients who showed elevated initial serum PCT level, 20 patients (80%) had a combined systemic infection. 14 patients (6.7%) had a sepsis, 3 patients (14.2%) had a urinary tract infection and 2 (9.6%) had a pneumonia. 14 patients (41.2%) showed elevation of serum PCT level during treatment. Among them, 9 patients (64.3%) had a combined infection such as sepsis and urinary tract infection. Conclusion : Serum CRP showed more sensitivity compared to serum PCT in patients with spinal infection. Patients with spinal infection who showed elevated serum PCT level should be investigated for combined infection and proper antibiotics should be applied.

CMV Infection in AIDS Patients Depends on the Decrease of CD4+ T Cell Count (AIDS 환자에서 CD4+ T 세포수 감소에 따른 CMV 감염)

  • Cho, Young-Keol;Kim, Yoo-Kyum;Oh, Won-Il;Cho, Goon-Jae
    • The Journal of Korean Society of Virology
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    • v.28 no.4
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    • pp.359-368
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    • 1998
  • Cytomegalovirus is the most common cause of life-threatening viral infection in HIV-infected patients. This study was done prospectively to investigate the incidence of CMV infection according to the decrease of CD4+ T cell count (CD4+) in Korean AIDS patients. Thirty-nine HIV-infected patients diagnosed before 1994 were followed for regular immunological monitoring. We have used urine shell vial method for the CMV detection from 1994 and have also checked clinical findings. Positive urine culture rate definitely depended on the CD4+ as follows; 45%, 22%, 17%, 11% and 0%, CD4+ <50, 50-100, 100-200, 200-500 and >500, respectively. Except culture positive 2 patients with CD4+ of $200{\sim}300/{\mu}l$, all eight culture positive patients with CD4+ less than $200/{\mu}l$ showed CMV related diseases on or before urine culture. But, we could not get a positive culture for a late AIDS patient with vision loss. With ganciclovir therapy, all culture results were at least negative just after or on late of first 14 days-ganciclovir infusion-course. These data suggest that the incidence of CMV disease in Korean AIDS patients is very high, and early diagnosis and treatment for CMV diseases is required for the prevention of life threatening results.

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The impact of caudally administrated tramadol on immune response and analgesic efficacy for pediatric patients: a comparative randomized clinical trial

  • Sayed, Jehan Ahmed;Elshafy, Sayed Kaoud Abd;Kamel, Emad Zareif;Riad, Mohamed Amir Fathy;Mahmoud, Amal Ahmed;Khalaf, Ghada Shalaby
    • The Korean Journal of Pain
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    • v.31 no.3
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    • pp.206-214
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    • 2018
  • Background: Immune responses appear to be affected by anesthetics and analgesics. We investigated the effects of caudal tramadol on the postoperative immune response and pain management in pediatric patients. Methods: Sixty ASA-I pediatric patients aged 3-10 years undergoing lower abdominal surgery. Patients were randomly assigned either to a caudal bupivacaine (0.25%) group (group B), or a group that received caudal tramadol (1 mg/kg) added to the bupivacaine (0.25%) (group T). Both were diluted in a 0.9% NaCl solution to a total volume of 1ml/ kg. The systemic immune response was measured by collecting blood samples preoperatively, at the end of anesthesia, and at 24 and 72 hours postoperatively, and studied for interleukin IL-6, C-reactive proteins (CRP) cortisol levels, and leucocytes with its differential count. Postoperative pain was assessed along with sedation scales. Results: Postoperative production of IL-6 was significantly higher in group B at the end of anesthesia, than at the $24^{th}$ hour, and at the $72^{nd}$ hour in group B and group T, respectively. The immune response showed leukocytosis with increased percentages of neutrophil and monocytes, and a decreased lymphocyte response rate within both groups with no significant differences between the groups. Cortisol and CRP were significantly higher in group B. Conclusions: Adding tramadol to a caudal bupivacaine block can attenuate the pro-inflammatory cytokine response, Cortisol, and CRP in children undergoing lower abdominal surgery.

The influence of Self-efficacy on Activities of Daily Living in Patients with Rheumatoid Arthritis (류마티스 관절염환자의 자기효능감에 따른 질병상태와 일상활동의 정도)

  • Lee, Hae Ran;Park, Jeong Sook
    • Korean Journal of Adult Nursing
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    • v.12 no.1
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    • pp.5-16
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    • 2000
  • The aim of this study was to investigate the differences in the level of disease condition and ADL by self-efficacy in patients with rheumatoid arthritis. The subjects of the study consisted of eighty-four outpatients with rheumatoid arthritis at a university hospital in Taegu between July 20, 1999 and August 25, 1999. The instruments used in this study were the self-efficacy developed by Lorig et al. (1989), the pain scale developed by Lee and Song(1987), the erythrocyte sedimentation rate(ESR), the pain joint count to measure disease condition scale, and the ADL scale developed by Katz et al. (1970) and Barthel(1973). Analysis of data was done by use of descriptive statistics: Pearson Correlation, Chi-square test, t-test, ANOVA and Scheffe, with the SPSS program. The major findings can be summarized as follows: 1. The first hypothesis, "There will be differences in the level of disease condition by self-efficacy in patients with rheumatoid arthritis" was partially supported. 1-1. "There will be differences in the level of pain by self-efficacy in patients with rheumatoid arthritis" was supported(F=3.422, p=.037). 1-2. "There will be differences in the level of ESR by self-efficacy in patients with rheumatoid arthritis" was the Disease Condition and supported (F=3.314, p=.041). 1-3. "There will be differences in the level of pain joints count by self-efficacy in patients with rheumatoid arthritis" was rejected(F=2.602, p=.080). 2. The second hypothesis, "There will be differences in the level of ADL by self-efficacy in patients with rheumatoid arthritis" was supported(F=7.067, p=.001). With the above results, it can be concluded that the higher level of self-efficacy contributed to the better level of disease condition and ADL in patients with rheumatoid arthritis. Therefore, by providing nursing intervention to promote the level of self-efficacy of rheumatoid arthritis patients with low self-efficacy, disease condition and ADL would be much better.

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