• 대한본초학회지
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• 제37권1호
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• pp.31-39
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• 2022

Objectives : It is very important to know the exact dosage of the Decoctions in 《Treatise on Cold Damage Diseases》. This study identified the characteristics of 15 Medicinal marked in volume and calculated their dosages in weight. Methods : The origin, processing methods, and properties of 15 Medicinal were identified. The shape of the appropriate container that measures the volume of one seung was estimated, and the dosage in volume was converted into weight. These were compared with the dosages indicated by weight or count. Results : The 15 Medicinal were categorized into liquids, powders, and grains. Ten items had only one dosage, of which three items had one seung, and seven items had 0.5 seung. Five items had two different dosages, of which four items had one or 0.5 seung, and only Suis Fel was 0.2 or 0.1 seung. Pinelliae Tuber and Urine were marked as 0.5 seung for convenience of measurement, although 0.4 seung were accurate. There were 20 different dosages in total, and when converted into weight, they matched 1, 2, 3, 4, 6, 8, or 16 Ryang, with none of 5 Ryang. Some exceptions that did not fit in the above were indicated by weight or count. Conclusions : In the Decoctions of 《Treatise on Cold Damage Diseases》, dosages of 15 Medicinal were easy to measure by volume, and when converted into weight, they were consistent with the dosages originally indicated in weight or count.

• Asian-Australasian Journal of Animal Sciences
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• 제20권2호
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• pp.263-272
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• 2007

This experiment was conducted to examine the effects of cage type (CT) and cage density (CD) on physiological variables in growing rats. Sprague Dawley rats (n=108) weighing an average of 46 g were housed in metallic cage with woodchip bedding (MCWB), metallic cage with wire mesh (MCWM), and plastic shoebox with woodchip bedding (PCWB) separately by sex at normal ($160-cm^2/rat$, ND) and high ($80-cm^2/rat$, HD) CD from 3 to 10 wks of age. All cages were in dimension of $24{\times}40{\times}20$ cm ($W{\times}D{\times}H$). At the end of the experiment, blood samples were collected and 6 rats from each cage were sacrificed. No death was observed among rats at ND, whereas mortality rate at HD was 22.3% for males and 13.9% for females. Heart weight was affected by CT. Doubling CD caused 23, 11.8, 17.9, 8.6, 6.9, and 16.4% decreases in BW and weights of heart, liver, kidney, testis, and ovary, respectively. Except for adrenal gland, other organs for males were heavier than for females. Liver weight of males and females responded differently to CT and CD. Comparing with females, males had 7.3 and 5.2% heavier and 9.9% lighter liver weights in MCWB, MCWM, and PCWB, respectively. As CD doubled, liver weight for males and females decreased by 22.4 and 13.1%, respectively. Mean adrenal gland weight increased by 8.4% and decreased by 9.7% for males and females, respectively, with doubling CD. CT affected glucose, TG, Ca, and ALP levels. However, CD did not alter blood chemistry. Rats housed in metallic cages had greater neutrophil count and neutrophil:lymphocyte ratio than rats housed in plastic cages. Doubling CD caused a 24.2% increase in lymphocyte count. There were CT by CD, CT by sex, and CD by sex interaction effects on lymphocyte count. Doubling CD caused 0.1% decrease and 49.8 and 26.7% increases in lymphocyte count for rats housed in MCWB, MCWM, and PCWB, respectively. Comparing with females, lymphocyte count for males housed in MCWB, MCWM, and PCWB had 8.9 and 12.9% greater and 30.3% less lymphocyte counts, respectively. Lymphocyte count decreased by 4.12% for males, whereas it increased by 61.0% for females as CD doubled. Doubling CD resulted in 2.5 and 2.3% increases in erythrocyte count and hematocrit value. These data suggest that animals perform better in metallic cages than in plastic cages and that cage density had pronounceable effects on physiological parameters in a cage type and sex dependent-manner.

• Clinical and Experimental Pediatrics
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• 제54권2호
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• pp.69-78
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• 2011

Purpose: The aim of this study was conducted to investigate the mean nRBC count in very low births weight infants (VLBWIs) and to determine the usefulness of the nRBC as an independent prognostic factors of perinatal complications in VLBWIs. Methods: This study was conducted on 112 VLBWIs who were hospitalized in the neonatal intensive care unit (NICU) of the author's hospital within the period from March 2003 to and May 2008. Based on the infants' nucleated red blood cells (nRBC) counts at birth, on the third day after birth, on the seventh day after birth, in the second week after birth, and in the fourth week after birth in the medical records, the correlation between nRBC or absolute nRBC counts with birth weight, gestational age, and other perinatal outcomes were retrospectively investigated. Results: In VLBWIs, their mean nRBC and absolute nRBC counts were showing a gradual decrease after birth, and they were consisteantly kept at low values since one week after and inversely proportional to the birth weights. The mean nRBC counts based on the stage after birth showed a significant correlation with perinatal death, necrotizing enterocolitis, and severe intraventricular hemorrhage. Conclusion: The increase in the nRBC count showed a significant correlation with having a severe intraventricular hemorrhage, necrotizing enterocolitis, and perinatal death in VLBWIs. If an increase or no decrease in the nRBC count after birth is observed, newborninfant care precautions should be required.

• 한국정보통신학회논문지
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• 제16권3호
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• pp.470-475
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• 2012

EPCglobal Class-1 Gen-2 RFID 시스템의 Q-알고리즘에서는 슬롯-카운트 매개변수인 $Q_{fp}$ 값에 대한 초기 값이 정의되어 있지 않고, 슬롯-카운트의 크기를 증감시키기 위한 매개변수인 가중치 C의 값이 정해져 있지 않다. 따라서 태그의 수가 적은 상태에서 초기 $Q_{fp}$ 값을 크게 하면 빈 슬롯이 많이 발생하고, 태그의 수가 많은 상태에서 초기 $Q_{fp}$값을 적게 하면 충돌이 많이 발생한다. 또한 적절하지 못한 가중치를 선택할 경우 빈 슬롯 또는 충돌 슬롯이 많이 발생할 수 있다. 이로 인하여 질의 라운드 동안 최적의 프레임 크기에 수렴하는 속도가 늦어지므로 성능이 저하되는 문제점이 있다. 본 논문에서는 태그 수를 추정하여 최적의 초기 $Q_{fp}$ 값을 할당하고 현재의 슬롯-카운트 크기에 따라 가중치를 결정하는 기법을 제안하고, 이에 대한 성능을 분석한다.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2012년도 추계학술대회
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• pp.635-637
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• 2012

In Gen-2 Q-algorithm, the value of initial $Q_{fp}$ and weight C is not defined in the standard. If we let the initial $Q_{fp}$ be large or small, the number of empty slot will be large during the initial query round or almost all the slots will be collided, respectively. Also, if the reader selects an inappropriate weight, there are a lot of empty or collided slots. As a result, it is anticipated that the performance will be declined because the frame size does not converge to the optimal point quickly during the query round. In this paper, we analyze how the performances of Gen-2 Q-algorithm will be affected by the weight and initial slot-count size.

• 한국식품영양학회지
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• 제32권5호
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• pp.560-564
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• 2019

The purpose of this study was to analyze the effects of the pre-treatment method on the measurement of probiotic cell counts. The probiotic cell count was not significantly different in the pre-treatment method such as experimenters, diluted solution, medium, and homogenization duration. The mean value of probiotic cell count with capsule was $2.2{\times}10^{10}{\pm}9.5{\times}10^9CFU/g$. This probiotic cell count was converted into $2.8{\times}10^{10}{\pm}1.2{\times}10^{10}CFU/g$ based on the net weight. The mean value of probiotic cell count without capsules was $4.3{\times}10^{10}{\pm}1.8{\times}10^{10}CFU/g$. As a result of this comparison, probiotic cell count showed significant difference with and without capsules. Thus, it is suggested that the probiotic cell count is measured by removing the capsule in capsule probiotics.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2004년도 ICCAS
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• pp.1338-1341
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• 2004

In this paper, we have proposed a new approach of routing and wavelength assignment algorithms, called Possible Available Wavelength (PAW) algorithm. The weight of a link is used as the main factor for routing decision in PAW algorithm. The weight of a link is defined as a function of hop count and available wavelengths. This function includes a determination factor of the number of wavelengths that are being used currently and are supposed to be available after a certain time. The session requests from users will be routed on the links that has the greatest number of link weight by using Dijkstra's shortest path algorithm. This means that the selected lightpath will has the least hop count and the greatest number of possible available wavelengths. The impact of proposed link weight computing function on the blocking probability and link utilization is investigated by means of computer simulation and comparing with the traditional mechanism. The results show that the proposed PAW algorithm can achieve the better performance in terms of the blocking probability and link utilization.

• 한국식품위생안전성학회지
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• 제13권2호
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• pp.87-93
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• 1998

Tannic acid(0.5mg/ml , 1.0mg/ml, 2.0mg/ml)와 카드뮴(20mg/kg)을 마우스에 경구투여한 결과는 다음과 같다. 1.Tannic acid와 카드뮴을 투여한 마우스의 증체량과 음수소비량에 변화가 있었으나, 카드뮴투여에 의한 변화는 tannic acid 투여에 의하여 감소되었다. 2. 카드뮴투여에 의하여 간장의 상대중량과 뇌 상대중량이 대조군에 비하여 유의한 변화가 있었으며, tannic acid 1.0mg/ml 투여군에서는 간장의 상대중량, 폐장의 상대중량, 흉선의 상대중량도 유의하게 변화하였다. (P<0.05). 3. Hemoglobin contents, packed cell volume, platelet count, neutrophill count 등의 혈액학적인 변화는 대조군에 비하여 카드뮴 투여군에서 유의한 변화가 인정되었다. 그러나 이러한 유의한 변화가 tannic acid를 동시 투여한 군에서는 나타나지 않았다. 4. 카드뮴을 투여한 군에서는 혈청학적 변화(ALT, AST, BUN와 creatinine)가 있었으나 tannic acid 0.5, 1.0, 2.0 mg/ml을 동시 투여한 군에서는 회복되는 경향이 나타났다. 위의 결과로 미루어 카드뮴 투여에 의한 독성이 tannic acid을 2.0mg/ml/day 이상 4주간 투여했을 때 경감효과가 나타날 수 있었다. 그러나, 카드뮴과 같은 중금속의 독성에 tannic acid가 어떻게 경감효과를 나타내는지에 대한 작용기전의 연구가 더 필요할 것으로 사료된다.

• Asian-Australasian Journal of Animal Sciences
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• 제23권11호
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• pp.1503-1509
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• 2010

Forty-eight 40-wk-old Hi-sex laying hens were individually caged in an environmentally controlled house to evaluate the effect of garlic (Allium Sativum) juice administration on egg production, egg quality, and yolk cholesterol. Garlic juice was prepared by blending pealed garlic cloves with distilled water (1:1, w/w). Hens were randomly divided into four equal groups; one served as a control and the other three groups were individually gavaged, 3.75 ml, 7.5 ml, or 15 ml garlic juice, three times a week, which respectively represented 0.25, 0.50 and 1% of body weight. Egg production was recorded on a daily basis; egg weight, albumen height, albumen and yolk pH, Haugh unit, and bacterial count of E. coli-challenged eggs were recorded at day of oviposition (day-1) and after 5 and 10 days of storage at room temperature. Yolk cholesterol content was analyzed for five successive weeks. Garlic juice increased (p<0.05) egg weight and mass with no change in egg production intensity. Garlic juice administration recorded higher (p<0.05) albumen height and improvement in Haugh unit. Also, eggs from garlic-treated hens recorded lower (p<0.05) albumen and yolk pH when compared to eggs collected from control hens. Garlic reduced (p<0.05) the $log_{10}$ of bacterial count in egg contents linearly when challenged with E. coli. Egg-yolk cholesterol content was not influenced by garlic juice administration. It is concluded that garlic juice improved performance characteristics and may increase egg shelf life as indicated by egg quality improvement and lower bacterial count of E. coli-challenged eggs. The levels of garlic juice used in this study were insufficient to influence egg yolk cholesterol.

• Communications for Statistical Applications and Methods
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• 제29권2호
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• pp.239-250
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• 2022

In many applications, we frequently encounter correlated multiple outcomes measured on the same subject. Joint modeling of such multiple outcomes can improve efficiency of inference compared to independent modeling. For instance, in developmental toxicity studies, fetal weight and number of malformed pups are measured on the pregnant dams exposed to different levels of a toxic substance, in which the association between such outcomes should be taken into account in the model. The number of malformations may possibly have many zeros, which should be analyzed via zero-inflated count models. Motivated by applications in developmental toxicity studies, we propose a Bayesian joint modeling framework for continuous and count outcomes with excess zeros. In our model, zero-inflated Poisson (ZIP) regression model would be used to describe count data, and a subject-specific random effects would account for the correlation across the two outcomes. We implement a Bayesian approach using MCMC procedure with data augmentation method and adaptive rejection sampling. We apply our proposed model to dose-response analysis in a developmental toxicity study to estimate the benchmark dose in a risk assessment.