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A correlation of the modern scientific efficacy of Korean Red Ginseng with the legendary medicine for anti-aging and longevity (전설적 불로장생약과 고려홍삼의 현대 과학적 효능과의 연관성)

  • Yi, Yeong-Deuk
    • Journal of Ginseng Culture
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    • v.2
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    • pp.39-70
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    • 2020
  • In this paper, through the mutual interpretation and verification of the ancient Korean history books with different origin that have been suspected as false documents, it proves that they could be logically real records and reveal that the substance of the legendary 'medicine for anti-aging and longevity', which also had been mentioned in Chinese old books, is Korean ginseng. Furthermore, with reference to the modern Y chromosomal map of the migratory routes of mankind corresponding to these routes recorded in 「Budoji」, the core history book, the formation of the four ethnic constitution groups (Sasang Constitution) based on the life style of each human group has been estimated. And the cause of Korean ginseng with fever problem for Southeast Asians is their pharmacogenomic constitution problem by protopanaxatriol (PPT) type ginsenosides in ginseng. It was resolved with over production of protopanaxdiol (PPD) type ginsenosides against PPT type in Korean red ginseng as historical or scientific point of view. In addition, by explaining that the processing method to Korean red ginseng could increase red ginseng acidic polysaccharides (RGAP), the RGAP, PPD type ginsenosides, and arginine which is originally abundant in Korean ginseng could increase the expression of the 'heat shock proteins' as a kind of chaperone in the body, this paper presents the theory allowing the scientific interpretation of the efficacy of Korean red ginseng as an 'adaptogen' or 'medicine for anti-aging and longevity'. Lastly, through the consideration of the growing environment of American ginseng and Korean ginseng, the differences are presented.

The Search of Pig Pheromonal Odorants for Biostimulation Control System Technologies: Ⅱ. Holographic QSAR Model for Binding Affinities between Ligands of Volatile Odorants Molecules and Porcine Odorant Binding Protein (pOBP) (생물학적 자극 통제 수단으로 활용하기 위한 돼지 페로몬성 냄새 물질의 탐색: Ⅱ. 휘발성 냄새분자의 리간드와 Porcine Odorant Binding Protein (pOBP) 사이의 결합 친화력에 관한 홀로그래피적 QSAR 모델)

  • Sung N. D.;Park C. S.;Choi Y. S.;Myung P. K.
    • Reproductive and Developmental Biology
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    • v.29 no.1
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    • pp.43-48
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    • 2005
  • To search of a new porcine pheromonal odorants for biostimulation control system technologies to offer a potentially useful and practical way to improve reproductive efficiency in livestock species, the holographic quantitative structure activity relationship (HQSAR) model between odorants, 2-phenoxytetrahydrofurane (A), 2-cyclohexyl-oxytetrahydrofurane (B), derivatives and binding affinity constants (p[Od.]/sub 50/) for porcine odorant-binding protein (pOBP) as receptor of pig pheromones were derivated and disscused. The binding affinity constants of cyclohexyl substituents (A) for pOBP were higher (A>B) than that of phenyl substituents (B). It was revealed that the optimum HQSAR model XI using PLS analyses had a fragment length (5∼8) with chirality at 5 components and hologram length 97 bin, which had a cross-validated q²(predictablities) of 0.916, and a conventional correlation coefficient r² (fitness) of 0.988, respectively. From the atomic contribution, the C3 and C5 atom in 2-oxyfuryl group contributed to binding affinity constants, whereas the central carbon atom in tert-butyl group on the cyclohexyl ring and the C4 atom of furyl group parts showed no contribution.

Efficacy of minimal invasive cardiac output and ScVO2 monitoring during controlled hypotension for double-jaw surgery

  • Kim, Seokkon;Song, Jaegyok;Ji, Sungmi;Kwon, Min A;Nam, Dajeong
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.19 no.6
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    • pp.353-360
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    • 2019
  • Background: Controlled hypotension (CH) provides a better surgical environment and reduces operative time. However, there are some risks related to organ hypoperfusion. The EV1000/FloTrac system can provide continuous cardiac output monitoring without the insertion of pulmonary arterial catheter. The present study investigated the efficacy of this device in double jaw surgery under CH. Methods: We retrospectively reviewed the medical records of patients who underwent double jaw surgery between 2010 and 2015. Patients were administered conventional general anesthesia with desflurane; CH was performed with remifentanil infusion and monitored with an invasive radial arterial pressure monitor or the EV1000/FloTrac system. We allocated the patients into two groups, namely an A-line group and an EV1000 group, according to the monitoring methods used, and the study variables were compared. Results: Eighty-five patients were reviewed. The A-line group reported a higher number of failed CH (P = 0.005). A significant correlation was found between preoperative hemoglobin and intraoperative packed red blood cell transfusion (r = 0.525; P < 0.001). In the EV1000 group, the mean arterial pressure (MAP) was significantly lower 2 h after CH (P = 0.014), and the cardiac index significantly decreased 1 h after CH (P = 0.001) and 2 h after CH (P = 0.007). Moreover, venous oxygen saturation (ScVO2) decreased significantly at both 1 h (P = 0.002) and 2 h after CH (P = 0.029); however, these values were within normal limits. Conclusion: The EV1000 group reported a lower failure rate of CH than the A-line group. However, EV1000/FloTrac monitoring did not present with any specific advantage over the conventional arterial line monitoring when CH was performed with the same protocol and same mean blood pressure. Preoperative anemia treatment will be helpful to decrease intraoperative transfusion. Furthermore, ScVO2 monitoring did not present with sufficient benefits over the risk and cost.

Physical Colorimetric Properties and Psychological Sensibility Factor of Naturally Dyed Fabrics (천연염색직물의 물리적 색채 특성과 심리적 감성 요인)

  • Lee, Eu-Gene;Lee, Kyung-hyun;Cho, Gil-Soo
    • Science of Emotion and Sensibility
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    • v.19 no.3
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    • pp.3-14
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    • 2016
  • This study is aimed to measure the physical colorimetric property according to three conditions, natural dyestuffs (Gardenia, Sappan wood, Lac, Gardenia blue, Mugwort, and Indigo), fabric types (cotton, silk), and presence of mordant (without, with), and then to evaluate the psychological sensibility. Also, to perform analysis of variance (ANOVA) to find out the differences of physical properties according to the three natural dyeing conditions, and to analyze the relationship between physical property and psychological property by Pearson's correlation analysis and then suggest the prediction model by regression analysis using SPSS program (ver. 21.0). Finally, to propose a certain sensibility image map of naturally dyed fabrics, MDS (Multidimensional Scaling) was used, and as a result, Gardenia dyed fabrics having the color sensibilities such as 'hard' and 'heavy' were suggested to evoke masculine image, and to evoke feminine image, Sappan wood and Lac having 'bright', 'transparent', 'soft' and 'light' sensibilities were suggested. Natural image might be induced by using 'subdued' Mugwort dyed fabrics, and active image might be induced by using 'showy' Indigo dyed fabric.

Study on Major Mineral Distribution Characteristics in Groundwater in South Korea (국내 지하수의 주요 미네랄 분포 특성에 관한 연구)

  • Kim, Jeonghee;Ryoo, Rina;Lee, Jongsu;Song, Daesung;Lee, Young-Joo;Jun, Hang-Bae
    • Journal of Korean Society of Environmental Engineers
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    • v.38 no.10
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    • pp.566-573
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    • 2016
  • In order to support effective usage of groundwater as an alternative water resource in future, we investigated distribution characteristics of minerals related with human health. While recent studies tended to focus on small scale, this study broadened research area up to nationwide scale to understand groundwater hydrology and regional, geological distributions of minerals in wide area; we investigated mineral distributions of national groundwater monitoring networks, developed GIS-based mineral maps, and reviewed correlation with geological features. As a result, calcium showed the highest concentration among 5 minerals (Ca, Mg, Na, K, Si) and potassium showed the lowest. Calcium concentration in limestone and sedimentary zone was the highest, and that in pore-volcanic-rock zone was the lowest. While calcium, magnesium and sodium showed differences in concentrations in intrusive-igneous-rock and sedimentary zone, potassium was not within geological features. When we studied regional differences, there were no tendency, but Jeju and Gangwon area showed differences in concentrations of calcium and silica.

Estimation of Bathymetry Changes using Hyperspectral Measurements -Focused on Haeundae beach- (초미세분광 측정치를 이용한 해저지형 변화산정 - 해운대를 중심으로 -)

  • Yang, Intae;Jo, Young-Heon
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.34 no.4
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    • pp.1335-1342
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    • 2014
  • Shallow water depths were estimated using Compact Airborne Spectrographic Imager (CASI)-1500 and mapped to analyze the bottom bathymetry changes due to the rip currents in Haeundae beach, South Korea for the first time. The depths were estimated empirically using the maximum reflectances from 420nm to 597nm wavelength of CASI and 47 in situ water depth measurements, which were compared with ground-truth bathymetry measurements. The comparisons showed that the RMSE was 1.1m with a correlation coefficient of 0.76. In addition, CASI imagery showed remarkably detailed bottom features, especially those resulting from the rip currents within the beach. Two different channels carved by the rip current were analyzed and characterized with respect to the width and slope compared to surrounding regions. While the west side of the channel showed a wide and gentle slope, the east side of the channel showed a narrow and steep slope. The estimated bathymetry map revealed that the uneven offshore bottom features were related to the transport and accumulation of sediments by the rip current, which reaches hundreds of meters offshore. Accordingly, the accumulated sediments were estimated by adding topography changes compared to the depths of the non-rip current regions. The sediments were accumulated in off channels as much as almost twice the amount of annual sand supplements along the Haeundae beach.

The Relationship Between Tree Radial Growth and Topographic and Climatic Factors in Red Pine and Oak in Central Regions of Korea (중부지방 소나무와 참나무류의 반경생장량과 지형, 기후 인자의 관계)

  • Byun, Jae-Gyun;Lee, Woo-Kyun;Nor, Dae-Kyun;Kim, Sung-Ho;Choi, Jung-Kee;Lee, Young-Jin
    • Journal of Korean Society of Forest Science
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    • v.99 no.6
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    • pp.908-913
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    • 2010
  • This study analyzed the impact of climatic and topographic factors on tree radial growth of Pinus densiflora and Quercus spp. in central regions of Korea. To find the relationship between annual tree radial growth and climatic factors, we took the core samples from individual trees and measured the tree radial width. On the assumption that the tree radial growth is related to the tree age, we estimated the radial growth by the tree age as an independent variable. Also, we estimated the standard growth, defined as the radial growth of trees aged 30. As results, we found the spatial auto-correlation in the radial growth of the red pine. Moreover, we also found the relationships between climatic and topographic and the standard growth using the GAM (Generalized Additive Model). Increase of temperature has negative impacts on the radial growth of Pinus densiflora, while it has positive impacts on the radial growth of Quercus spp.. On the other hands, increase of precipitation has negative impacts on the radial growth of both species. Lastly, we predicted the spatial distribution changes of Pinus densiflora and Quercus spp. using the temperature increase scenario and the Geographic Information System (GIS) based forest type map. We could predict that Pinus densiflora is more vulnerable than Quercus spp. to climate change so that the habitats of Pinus densiflora will be gradually changed to the habitats of Quercus spp. in eastern coastal and southern regions of Korea after 60 years.

Analysis of Noise Influence on a Chaotic Series and Application of Filtering Techniques (카오스 시계열에 대한 잡음영향 분석과 필터링 기법의 적용)

  • Choi, Min Ho;Lee, Eun Tae;Kim, Hung Soo;Kim, Soo Jun
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.31 no.1B
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    • pp.37-45
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    • 2011
  • We studied noise influence on nonlinear chaotic system by using Logistic data series which is known as a typical nonlinear chaotic system. We regenerated Logistic data series by the method of adding noise according to noise level. And, we performed some analyses such as phase space reconstruction, correlation dimension, BDS statistics, and DVS Algorithms which are known as the methods of nonlinear deterministic or chaotic analysis. If we see the results of analysis, the characteristics of data series are gradually changed from nonlinear chaotic data series to random stochastic data series according to increasing noise level. We applied Low Pass Filter (LPF) and Kalman Filter techniques for the investigation of removing effect of the added noise to data series. Typical nonparametric method cannot distinguish nonlinear random series but the BDS statistic can distinguish the nonlinear randomness of the time series. Therefore this study used the BDS statistic which is well known as nonlinear statistical method for the investigation of randomness of time series for the effect of removing noise of data series. We found that Kalman filter is better method to remove the noise of chaotic data series even for high noise level.

Visualized Determination for Installation Location of Monitoring Devices using CPTED (CPTED기법을 통한 모니터링 시스템 설치위치 시각화 결정법)

  • Kim, Joohwan;Nam, Doohee
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.15 no.2
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    • pp.145-150
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    • 2015
  • Needs about safety of residents are important in urbanized society, elderly and small-size family. People are looking for safety information system and device of CPTED. That is, Needs and Installations of CCTV increased steadily. But, scientific analysis about validity, systematic plan and location of security CCTV is nonexistent. It is simply put these devised in more demanded areas. It has limits to look for safety of residents by increasing density of CCTVs. One of the characteristics of crime is clustering and stong interconnectivity. So, exploratory spatial data of crime is geo-coded using 2 years data and carried out cluster analysis and space statistical analysis through GIS space analysis by dividing 18 variables into social economy, urban space, crime prevention facility and crime occurrence index. The result of analysis shows cluster of 5 major crimes, theft, violence and sexual violence by Nearest Neighbor distance analysis and Ripley's K function. It also shows strong crime interconnectivity through criminal correlation analysis. In case of finding criminal cluster, you can find criminal hotspot. So, in this study I found concept of hotspot and considered technique about selection of hotspot. And then, selected hotspot about 5 major crimes, theft, violence and sexual violence through Nearest Neighbor Hierarchical Spatial Clustering.

Characteristics of the soil loss and soil salinity of upland soil in saemangeum reclaimed land in western South Korea

  • Kim, Young Joo;Lee, Su Hwan;Ryu, Jin Hee;Oh, Yang Yeol;Lee, Jeong Tae
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.316-316
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    • 2017
  • The objective of this study is to estimate quantitatively soil salinity and soil loss at upland soils in agriculture land region in Saemangeum reclaimed land on the south Korea coasts. Soil loss and soil salinity are the most critical problem at reclaimed tidal saline soil in Korea. The several thematic maps of research area such as land cover map, topographic and soil maps, together with tabular precipitation data used for soil erosion and soil salinity calculation. Meteorological data were measured directly as air temperature, wind speed, solar radiation, and precipitation. The experiment was conducted 2% sloped lysimeter ($5.0m{\times}20.0m$) with 14 treatments and it were separated by low salinity division (LSD) and high salinity division (HSD) install. The cation content in ground water increased during time course, but in the case of land surface water the content was variable, and $K^+$ was lower than that of $Na^+$ and $Mg^{2+}$. At the LSD under rainproof condition, the salinity was directly proportional to soil water content, but at the HSD the tendency was no reversed. In condition of rainproof, the amount of soil salinity was higher at the HSD than at the LSD. Positive correlation was obtained between the soil water content and available phosphorous content at the rainfall division, but there was no significance at the surface soil of the rainproof division. Sodium adsorption ratio and anion contents in soil were repressed in the order of vinyl-mulching > non-mulching > bare field. According to the result of analyzing soil loss, soil loss occurred in a vinyl-mulching, a non-mulching and a bare field in size order, and also approximately 11.2 ton/ha soil loss happened on the reclaimed land area. The average soil loss amount by the unit area takes place in a non-mulching and bare field a lot. Our results indicate that soluble salt control and soil erosion are critical at reclaimed tidal saline soil and the results can provide some useful information for deciding management plans to reduce soil loss and salt damage for stable crop production and diverse utilization or cultivation could be one of the management options to alleviate salt damage at reclaimed tidal saline soil in Korea.

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