• Journal of Integrative Natural Science
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• v.10 no.4
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• pp.209-215
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• 2017

CXC chemokine receptor 2 (CXCR2) is a prominent chemokine receptor on neutrophils. CXCR2 antagonist may reduce the neutrophil chemotaxis and alter the inflammatory response because the neutrophilic inflammation in the lung diseases is found to be largely regulated through CXCR2 receptor. Hence, in the present study, Topomer based Comparative Molecular Field Analysis (Topomer CoMFA) was performed on a series of CXCR2 antagonist named pyrimidine-5-carbonitrile-6-alkyl derivatives. The best Topomer COMFA model was obtained with significant cross-validated correlation coefficient ($q^2$ = 0.487) and non cross-validated correlation coefficients ($r^2$ = 0.980). The model was evaluated with six external test compounds and its $r^2{_{pred}}$ was found to be 0.616. The steric and electrostatic contribution map show that presence of bulkier and electropositive group around cyclopropyl ring may contribute more for improving the biological activities of these compounds. The generated Topomer CoMFA model could be helpful for future design of novel and structurally related CXCR2 antagonists.

• Journal of Integrative Natural Science
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• v.10 no.4
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• pp.192-196
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• 2017

Xanthine Oxidase is an enzyme, which oxidizes hypoxanthine to xanthine, and xanthine to uric acid. It is widely distributed throughout various organs including the liver, gut, lungs, kidney, heart, brain and plasma. It is involved in gout pathogenesis. Hence, in the present study, topomer based Comparative Molecular Field Analysis (topomer CoMFA) was performed on a series of Xanthine oxidase antagonist named 2-(indol-5-yl) thiazole derivatives. The best topomer CoMFA model was obtained with significant cross-validated correlation coefficient ($q^2$ = 0.572) and non cross-validated correlation coefficients ($r^2$ = 0.937). The model was evaluated with six external test compounds and its $r^2{_{pred}}$ was found to be 0.553. The steric and electrostatic contribution map show that presence of bulky and electropositive group in indole thiazole ring is necessary for improving the biological activities of the compounds. The generated topomer CoMFA model could be helpful for future design of novel and structurally related xanthine oxidase antagonists.

• Proceedings of the IEEK Conference
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• 2003.11a
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• pp.321-324
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• 2003

This paper presents a novel system that analyzes and recognizes a gait based on shape context on silhouette images. The main functions of the system consist of three steps: First, the system extracts the silhouette images from galt image sequence by performing a simple pre-processing and acquires the AGM(Averaged Gait Map) by averaging them. Next. it computes the cross-correlation between the AGMs. Finally, it classifies the AGMs based on the cross-correlation using nearest neighborhood classification. The proposed system uses two cues to classify a gait: One corresponds to biometric shape cue such as body height width. and body-part proportions. The other corresponds to gait cue such as stride length and amount of arm swing. Perceptionally, the biometric cues are sailent on the double support (both legs spread and touching the ground) while the gait cues on the midstance. Through a variety of experiments, it is proved that the property of a gait is mainly influenced by gait cues than biometric cues.

• Proceedings of the KSRS Conference
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• 2008.10a
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• pp.332-335
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• 2008

Newly developing SAR (Synthetic Aperture Radar) sensors commonly include high resolution X-band those data are expected to contribute various applications. Recent few studies are presenting potential of X-band SAR data in forest related application. This study tried to investigate the relationship between forest stand parameters and multi-band SAR normalized backscattering. Multi-band SAR data was radiometric corrected to compare signal from different forest stand condition. Then correlation coefficients were estimated between attribute of forest stand map and normalized backscattering coefficients. Although overall correlation coefficients are not high, only X-band shows strong relationship with DBH class than other bands. The signal of C- and L-band is composed of a large number of discrete tree components such as leaves, stems, even background soil. In forest, strength of radar backscattering is affected by complex parameters. Further study might be considered more various forest stand parameters such as canopy density, stand height, volume, and biomass.

• Journal of Mechanical Science and Technology
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• v.17 no.5
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• pp.758-765
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• 2003

An experimental investigation on the flow pattern and pressure drop was carried out for both an adiabatic and a diabatic two-phase flow in a horizontal tube with pure refrigerants R134a and R123 and their mixtures as test fluids. The observed flow patterns were compared to the flow pattern map of Kattan et al., which predicted well the present data over the entire regions of mass velocity in this study. The measured frictional pressure drop in the adiabatic experiments increased with an increase in vapor quality and mass velocity These data were compared to various correlations proposed in the past for the frictional pressure drop. The Chisholm correlation underpredicted the present data both for pure fluids and their mixtures in the entire mass velocity range of 150 to 600 kg/m$^2$s covered in the measurements, white the Friedel correlation was found to overpredict the present data in the stratified and stratified-wavy flow region, and to underpredict in the annular flow region.

• Journal of the Korea Society for Simulation
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• v.11 no.3
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• pp.49-58
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• 2002

It takes 2 or 3 months to manufacture memory device. Defect has to exist owing to hundreds of processes. If there are too many defects, the memory has to be rejected. But if there are a few defects, it will be more efficient and cost reducing for the company to use it by repairing. Therefore, laser-repair process is needed for such a reason and redundancy analysis is needed to establish correct target of laser-repair process. The equipment development company had provided the redundancy analysis and each development company had developed and provided separately. So, to analyze the similar type of defects, redundancy analysis time can be very different by the manufacture. The purpose of this research is to strengthen the competitive price and to apply correlation concept in business for reducing the redundancy analysis time to repair the defects

• Korean Journal of Remote Sensing
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• v.10 no.1
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• pp.43-53
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• 1994

By Using MOS-1 satellite image(taken on 24 April 1990, after slash and burn), Shifting cultivation areas were estimated for the sub-basin area. In tropical region to analyse the correlation between shifting cultivation rate and bifurcation rate network which was calculated from topographic map, PC Arc - Info and IDRISI GIS software were used. As the distribution rate of shifting cultivation increases, the bifurcation rate is high. From the correlation analysis between the shifting cultivation and drainage network, it was found that shifting cultivation leads to land degradation and head erosion at the stream valley. To prevent such problems, it is mecessary that shifting cultivation areas should be converted to permanent paddy fields.

• Proceedings of the SAREK Conference
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• 2006.06a
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• pp.176-181
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• 2006

Experiments of Counter-Current Flow Limit(CCFL or Flooding) is performed to improve the drawbacks of Wallis' Correlation which neglects the effects of channel size, channel length, injection method and the boundary conditions at the inlet of liquid and gas phase. In this study, CCFL is observed by changing shape of porous plate using air and water. Results show that as the size of porous increases, CCFL with round shape of the porous plate decreases. In the present study, a CCFL correlation is developed and the CCFL map is proposed based on the present experimental results. developed by this experimental study.

• Journal of Korea Multimedia Society
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• v.24 no.6
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• pp.796-804
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• 2021

In computer vision, visual tracking method addresses the problem of localizing an specific object in video sequence according to the bounding box. In this paper, we propose a tracking method by introducing the feature correlation comparison into the siamese network to increase its matching identification. We propose a way to compute location of object to improve matching performance by a correlation operation, which locates parts for solving the searching problem. The higher layer in the network can extract a lot of object information. The lower layer has many location information. To reduce error rate of the object center point, we built a siamese network that extracts the distribution and location information of target objects. As a result of the experiment, the average center error rate was less than 25%.

• JSTS:Journal of Semiconductor Technology and Science
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• v.16 no.5
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• pp.713-718
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• 2016

Predicting precise specifications of differential mixed-signal circuits is a difficult problem, because analytically derived correlation between process variations and conventional specifications exhibits the limited prediction accuracy due to the phase unbalance, for most self-tests. This paper proposes an efficient prediction technique to provide accurate specifications of differential mixed-signal circuits in a system-on-chip (SoC) based on a nonlinear statistical nonlinear regression technique. A spectrally pure sinusoidal signal is applied to a differential DUT, and its output is fed into another differential DUT through a weighting circuitry in the loopback configuration. The weighting circuitry, which is employed from the previous work [3], efficiently produces different weights on the harmonics of the loopback responses, i.e., the signatures. The correlation models, which map the signatures to the conventional specifications, are built based on the statistical nonlinear regression technique, in order to predict accurate nonlinearities of individual DUTs. In production testing, once the efficient signatures are measured, and plugged into the obtained correlation models, the harmonic coefficients of DUTs are readily identified. This work provides a practical test solution to overcome the serious test issue of differential mixed-signal circuits; the low accuracy of analytically derived model is much lower by the errors from the unbalance. Hardware measurement results showed less than 1.0 dB of the prediction error, validating that this approach can be used as production test.