• 제목/요약/키워드: Coronary Anatomy

검색결과 43건 처리시간 0.022초

Reversible effect of castration induced hypogonadism on the morphology of the left coronary arteries in adult male rabbits

  • Duncan Anangwe;Moses Madadi Obimbo;Ibsen Henric Ongidi;Peter Bundi Gichangi
    • Anatomy and Cell Biology
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    • 제57권1호
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    • pp.61-69
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    • 2024
  • Hypogonadism is associated with an increased risk of coronary artery disease. This study sought to describe the histomorphology of the left coronary arteries of the adult male rabbit following orchiectomy and subsequent testosterone administration. We included 20 adult male rabbits, divided into a baseline group (n=2), an interventional group subjected to castration only (n=6), an intervention group subjected to castration followed by testosterone injection (n=6), and a control group (n=6). Key variables under investigation were serum testosterone levels, the intima-media thickness of coronary arteries, smooth muscle cell density, and adventitial collagen fiber density. The mean coronary arteries' intimal medial thickness was significantly higher in the castrated group than in controls (0.488 mm and 0.388 mm, respectively), while the testosterone-injected group had a mean of 0.440 mm. Mean smooth muscle cell density was significantly lower in the castrated rabbits vs. controls (26.96% and 47.80%, respectively), this observation being reversed with testosterone injection (47.53%). Mean adventitial collagen fiber density was significantly higher in the castrated group than in controls (66.6% and 36.1%, respectively), with a marginal difference after testosterone injection (65.2%). This study demonstrates that castrationinduced hypogonadism causes morphological changes in the coronary arteries that are partly reversible using testosterone injections. These findings provide a morphological basis for understanding the role of testosterone in coronary arteries.

Analysis of Semantic Relations Between Multimodal Medical Images Based on Coronary Anatomy for Acute Myocardial Infarction

  • Park, Yeseul;Lee, Meeyeon;Kim, Myung-Hee;Lee, Jung-Won
    • Journal of Information Processing Systems
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    • 제12권1호
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    • pp.129-148
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    • 2016
  • Acute myocardial infarction (AMI) is one of the three emergency diseases that require urgent diagnosis and treatment in the golden hour. It is important to identify the status of the coronary artery in AMI due to the nature of disease. Therefore, multi-modal medical images, which can effectively show the status of the coronary artery, have been widely used to diagnose AMI. However, the legacy system has provided multi-modal medical images with flat and unstructured data. It has a lack of semantic information between multi-modal images, which are distributed and stored individually. If we can see the status of the coronary artery all at once by integrating the core information extracted from multi-modal medical images, the time for diagnosis and treatment will be reduced. In this paper, we analyze semantic relations between multi-modal medical images based on coronary anatomy for AMI. First, we selected a coronary arteriogram, coronary angiography, and echocardiography as the representative medical images for AMI and extracted semantic features from them, respectively. We then analyzed the semantic relations between them and defined the convergence data model for AMI. As a result, we show that the data model can present core information from multi-modal medical images and enable to diagnose through the united view of AMI intuitively.

Patient-Specific Mapping between Myocardium and Coronary Arteries using Myocardial Thickness Variation

  • Dongjin Han
    • International journal of advanced smart convergence
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    • 제13권2호
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    • pp.187-194
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    • 2024
  • For precise cardiac diagnostics and treatment, we introduce a novel method for patient-specific mapping between myocardial and coronary anatomy, leveraging local variations in myocardial thickness. This complex system integrates and automates multiple sophisticated components, including left ventricle segmentation, myocardium segmentation, long-axis estimation, coronary artery tracking, and advanced geodesic Voronoi distance mapping. It meticulously accounts for variations in myocardial thickness and precisely delineates the boundaries between coronary territories according to the conventional 17-segment myocardial model. Each phase of the system provides a step-by-step approach to automate coronary artery mapping onto the myocardium. This innovative method promises to transform cardiac imaging by offering highly precise, automated, and patient-specific analyses, potentially enhancing the accuracy of diagnoses and the effectiveness of therapeutic interventions for various cardiac conditions.

한국인 대동맥 근부의 해부학적 구조 (Anatomical Structures of the Aortic Root in Koreans)

  • 강민웅;유재현;임승평;이영;김시욱;김수일;정인혁;나명훈
    • Journal of Chest Surgery
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    • 제40권5호
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    • pp.321-328
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    • 2007
  • 배경: 대동맥 근부를 보존하는 심장수술이 점차 늘어남에 따라 대동맥 근부의 해부학적 구조에 대한 중요성 또한 증가하고 있다. 본 연구는 외과적 관점에서 필요한 대동맥 근부를 한국인 해부학 실습용 시신에서 실측하여 대동맥 근부의 진단 및 수술적 처치의 기준으로 하고자 한다. 대상 및 방법: 사인이 심혈관 질환이 아닌 시신 62구 중 대동맥 판막이 쌍엽인 1구, 기술적 오류로 대동맥 근부가 손상된 4구, 고정기간 중 변형이 심한 10구를 제외한 47예를 대상으로 하였다. 각 교련사이 간격, 대동맥 동의 높이, Sinotubular junction 및 aortic annulus의 길이를 측정하여 비교하였다. 결과: 시신의 사망 나이는 평균 61.3이었으며 남성이 31, 여성이 16구였다. 각 교련사이 간격은 Right coronary sinus $20.73{\pm}2.23mm$, Non coronary sinus $19.34{\pm}2.08mm$, Left coronary sinus $18.58{\pm}2.15mm$였다. 각 대동맥동의 높이는 Right coronary sinus $20.59{\pm}2.48$, Non coronary sinus $18.61{\pm}2.26mm$, Left coronary sinus $17.95{\pm}19mm$였으며, 통계 분석에서 교련사이에 길이 및 대동맥동의 높이는 Right coronary sinus가 가장 컸으며, Non coronary sinus, Left coronary sinus 순으로 나타났다. Sinotubular junction의 길이는 $70.73{\pm}5.94mm$, aortic annulus는 $77.94{\pm}5.63mm$였으며 Sinotubular junction의 길이, 대동맥 판륜의 길이와 대동맥 판륜에 대한 Sinotubular junction의 길이의 비를 각각 나이와 비교 분석했을 때 상관관계가 없었다(p=0.920, p=0.111, p=0.073). 대동맥 판륜과 sinotubular junction의 기울기는 $2.03^{\circ}$에서 $7.77^{\circ}$ (평균$=4.90^{\circ}$)였다. 결론: 각 교련 사이 간격 및 대동맥동의 높이는 non-parametric ANOVA test 결과 Right coronary sinus, Non coronary sinus, Left coronary sinus의 순으로 유의한 크기차이를 보였다(p=0.00). Sinotubular junction의 둘레 길이는 대동맥 판륜의 길이보다 9.3% 작았고 sinotubular junction이 aortic annulus에 대해 좌후측으로 기울어져 있었다.

A cadaveric study of arteriovenous trigone of heart: the triangle of Brocq and Mouchet

  • Swati Bansal;Rajiv Jain;Virendra Budhiraja;Shveta Swami;Rimpi Gupta
    • Anatomy and Cell Biology
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    • 제56권2호
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    • pp.205-210
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    • 2023
  • Left coronary artery divides into anterior interventricular branch and circumflex branch. As both the arteries run in their corresponding grooves, an arteriovenous trigone is formed between conus arteriosus and left auricle called triangle of Brocq and Mouchet. The triangle base is formed by great cardiac vein. This study aims to describe the frequency of triangle and its type and relationship between various boundaries and content of triangle and to supplement the existing knowledge of clinicians. This observational and descriptive study was conducted on 40 formalin fixed cadaveric hearts in department of anatomy, Kalpana chawla government medical college. The triangle was found in 92.5% of specimen with most common type being closed (51.3%) which is followed by inferiorly open in 35.1%, superiorly open in 8.1% and completely open in 5.4% hearts. Most frequent content of triangle was median artery followed by diagonal branches of anterior interventricular and circumflex branches. The mean area of the triangle was 246.3 mm2. Relationship of vein with two arterial branches was either superficial or deep. The knowledge of different patterns of existence will be required for angiographic procedures. Further the triangle is a potential epicardial access route to left fibrous ring. Thus detailed knowledge of variations will help cardiologist to achieve better outcome in interventional procedures with minimal complications.

좌주간부 관상동맥에 관한 혈류역학적 분석 (I) (Hemodynamic Analysis of Pig's Left Common Coronary Artery (I))

  • 박정수;장주희;문수연;신세현
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2003년도 춘계학술대회
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    • pp.1923-1929
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    • 2003
  • The present study investigated the microcirculation of blood in the left common artery (LCCA). In order to develop a mathematical model for microcirculation in LCCA, the present study adopted preexisted set of measured morphological data on anatomy, mechanical properties of the coronary vessels, viscosity of blood, the basic laws of physics, and the appropriate boundary conditions. In this study, the statistical distribution of blood pressure, blood flow, and blood volume in the LCCA were determined based on the anatomical branching pattern of the coronary arterial tree and the statistical data of blood vessel dimensions. Our calculations were in good agreement with the previous studies. The present results showed that the mean longitudinal pressure drop profile was function of the vessel order numbers. It was found that the normalized pressure drop was a logarithmic function of the compliance.

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A rare type of single coronary artery with right coronary artery originating from the left circumflex artery in a child

  • Kim, Jong Min;Lee, Ok Jeong;Kang, I-Seok;Huh, June;Song, Jinyoung;Kim, Geena
    • Clinical and Experimental Pediatrics
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    • 제58권1호
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    • pp.37-40
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    • 2015
  • The presence of a single coronary artery is a rare congenital anomaly; such patients often present with severe myocardial ischemia. We experienced the case of a 13-year-old girl with the right coronary artery originating from the left circumflex artery. She visited our Emergency Department owing to severe chest pain; her cardiac enzyme levels were elevated, but her initial electrocardiogram (ECG) was normal. Echocardiography showed normal anatomy and normal regional wall motion. When she presented with recurrent chest pain on admission, the ECG showed significant ST-segment elevation in the left precordial leads and inferior leads with ST-segment depression in aVR lead, suggesting myocardial ischemia, and her cardiac enzyme levels were also elevated. We performed coronary angiography that showed a single right coronary artery originating from the left circumflex artery without stenosis. We confirmed the presence of a single coronary artery using coronary computed tomography. In addition, the treadmill test that was performed showed normal results. She was discharged from the hospital without any medications but with a recommendation of a regular followup.

좌주간부 관상동맥(LCCA)에 관한 혈류역학적 분석 (II) (Hemodynamic Analysis of Pig's Left Common Coronary Artery (LCCA) (II))

  • 문수연;장주희;박정수;신세현
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2003년도 춘계학술대회
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    • pp.2043-2047
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    • 2003
  • The distributions of blood pressure, blood flow, and blow volume in the left common artery (LCCA) were determined using the lumping parameter method. In order to develop a mathematical model for microcirculation in LCCA, the present study adopted preexisted set of measured morphological data on anatomy, mechanical properties of the coronary vessels, viscosity of blood, the basic laws of physics, and the appropriate boundary condition. Pressures and volumes of blood and flow resistance were expressed in terms of electrical voltages, current, and resistances, respectively, in the electrical analog model. The results of two mathematical models, symmetrical and asymmetrical models, were compared with other investigator's data. The present results were in good agreement with previous studies. It was found that the mean pressure profiles were similar in both models.

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A marginal branch of the left hepatic artery running along the umbilical vein and supplying the anterior surface of the liver left lobe: a report of 5 cases in 12 Japanese human fetuses

  • Ji Hyun Kim;Shogo Hayashi;Gen Murakami;Jose Francisco Rodriguez-Vazquez;Hiroshi Abe
    • Anatomy and Cell Biology
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    • 제56권4호
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    • pp.579-583
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    • 2023
  • In human fetuses, the left hepatic artery (LHA) issues the marginal artery that runs along the umbilical vein and, sometimes, reaches the umbilicus. The further observation demonstrated that, in 5 of 12 Japanese midterm fetuses (crown-rump length mm: 46, 50, 54, 59, 102), the marginal artery issued not only a thin umbilical branch but also a liver parenchymal branch that took a posterosuperior recurrent course in a peritoneal fold and supplied the anterior surface of the liver left lobe (segment III). However, in 22 Spanish fetuses of which gestational ages corresponded to the Japanese ones, we did not find the parenchymal branch. Therefore, between human populations, there seemed to be a considerable difference in the incidence as to whether or not the marginal artery issues the liver parenchymal branch. The parenchymal branch might be degenerated at the later stages due to friction between the liver free surface and growing diaphragm.

Vascular anatomy and their variations in Situs inversus totalis using postmortem computed tomographic angiography

  • Dawa Zangpo;Hironobu Nakane;Morio Iino
    • Anatomy and Cell Biology
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    • 제56권1호
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    • pp.155-159
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    • 2023
  • Studies describing the vascular systems and their variations in Situs inversus totalis (SIT) from a whole-body computed tomographic (CT) angiography perspective are lacking. We report a case of SIT in which postmortem CT angiography (PMCTA) was performed as a part of the forensic death investigation and incidentally detected several vascular variations in it. The PMCTA procedure was performed using the multiphase PMCTA protocol. Almost all major vessels were visualized, indeed in a completely reversed pattern. Contrast mixture flow interruptions were noted in the right coronary arterial branches suggesting possible blockage, upon which autopsy revealed >90% vessel occlusions at several locations. As such the cause of death was due to ischemic heart disease. Anomalous origins of the right internal mammary artery; abnormal left thyrocervical trunk and variations in the drainage of testicular veins were noted. Our findings might be helpful to clinicians and add to the body of literature on SIT.