• Title/Summary/Keyword: Core Service

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Bioequivalence of EtodolTM Tablet to KuhnillodineTM Tablet (Micronized Etodolac 200 mg) (건일로딘 정(미결정에토돌락 200 mg)에 대한 에토돌 정의 생물학적동등성)

  • Lee, Jung-Ae;Lee, Yun-Young;Cho, Tae-Seob;Park, Young-Joon;Moon, Byoung-Seok;Kim, Ho-Hyun;Lee, Ye-Rie;Lee, Hee-Joo;Lee, Kyung-Ryul
    • Journal of Pharmaceutical Investigation
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    • v.34 no.4
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    • pp.319-325
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    • 2004
  • A bioequivalence of $Etodol^{TM}$ tablets (Yuhan corporation) and $Kuhnillodine^{TM}$ tablets (Kuhnil Pharm. Co., Ltd.) was evaluated according to the guideline of Korea Food and Drug Administration (KFDA). Single 200 mg dose of etodolac of each medicine was administered orally to 24 healthy male volunteers. This study was performed in a $2{\times}2$ crossover design. Concentrations of etodolac in human plasma were monitored by a high-performance liquid chromatography. $AUC_t$ (the area under the plasma concentration-time curve from time zero to 24 hr) was calculated by the linear trapezoidal rule method. $C_{max}$ (maximum plasma drug concentration) and $T_{max}$ (time to reach $C_{max}$) were compiled from the plasma concentration-time data. Analysis of variance was performed using logarithmically transformed $AUC_t$ and $C_{max}$. No significant sequence effect was found for all of the bioavailability parameters. The 90% confidence intervals of the $AUC_t$ ratio and the $C_{max}$ ratio for $Etodol^{TM}/Kuhnillodine^{TM}$ were 1.01-1.10 and 0.87-1.06, respectively. This study demonstrated a bioequivalence of $Etodol^{TM}$ and $Kuhnillodine^{TM}$ with respect to the rate and extent of absorption.

Bioequivalence of BestidineTM Tablet to Dong-A GasterTM Tablet (Famotidine 20 mg) (동아가스터 정(파모티딘 20 mg)에 대한 베스티딘 정의 생물학적동등성)

  • Park, Chang-Hun;Joung, Sun-Koung;Choi, Mee-Hee;Kim, Ho-Hyun;Lee, Ye-Rie;Lee, Hee-Joo;Lee, Kyung-Ryul
    • Journal of Pharmaceutical Investigation
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    • v.34 no.6
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    • pp.505-511
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    • 2004
  • A bioequivalence study of $Bestidine^{TM}$ tablets (Choong Wae Pharma. Corp., Korea) to Dong-A $Gaster^{TM}$ (Dong-A Pharmaceutical Co., Ltd., Korea) tablets was conducted according to the guidelines of Korea Food and Drug Administration (KFDA). Twenty four healthy male Korean volunteers received each medicine at the famotidine dose of 40 mg in a $2{\times}2$ crossover study. There was a one-week wash out period between the doses. Plasma concentrations of famotidine were monitored by a high-performance liquid chromatography for over a period of 12 hours after the administration. $AUC_t$ (the area under the plasma concentration-time curve from time zero to 12 hr) was calculated by the linear trapezoidal rule method. $C_{max}$ (maximum plasma drug concentration) and $T_{max}$ (time to reach $C_{max}$) were compiled from the plasma concentration-time data. Analysis of variance was carried out using logarithmically transformed $AUC_t$ and $C_{max}$. No significant sequence effect was found for all of the bioavailability parameters indicating that the crossover design was properly performed. The 90% confidence intervals of the $AUC_t$ ratio and the Cmax ratio for $Bestidine^{TM}/Gaster^{TM}$ were log 0.90-log 1.06 and log 0.98-log 1.20, respectively. These values were within the acceptable bioequivalence intervals of 0.80-1.25. Thus, our study demonstrated the bioequivalence of $Bestidine^{TM}$ and $Gaster^{TM}$ with respect to the rate and extent of absorption.

The Role of Communication in Linking IT and Logistics Service (IT와 물류서비스 관계에서 커뮤니케이션의 역할에 관한 연구)

  • Lee, Min-Ho
    • Journal of Information Technology Services
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    • v.7 no.4
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    • pp.301-317
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    • 2008
  • Product-related services in manufacturing industry are different from typical services in service industry. Product-related services ensure proper product functioning, provide additional repurchase, and offer attractive margin Product-related services in manufacturing industry are not core activity but taking supporting roles, while services in typical service industry are core parts. The purpose of this study is to investigate the role of communication in linking IT and product-related logistics service in manufacturing industry. The relationships among IT, communication, logistics service and business performance are explored using a path analysis. The empirical research reveals that higher degree of IT usability leads to increased communication, and in turn, communication affects logistics service, and ultimately business performance. In addition, this study shows communication plays an intermediate role in linking IT to logistics service.

Core competency in disaster management of 119 paramedics (119구급대원의 재난관리 핵심역량에 관한 연구)

  • Kim, Jin-Hyeon;Choi, Eun-Sook
    • The Korean Journal of Emergency Medical Services
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    • v.21 no.3
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    • pp.35-48
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    • 2017
  • Purpose: The purpose of the study was to investigate the core competency of disaster management of 119 paramedics. Methods: A self-reported questionnaire was completed by 242 paramedics in C area from April 28 to May 12, 2017. The study instrument included general characteristics of the subjects (4 items), disaster experience, recognition, and preparedness (20 items), and importance and performance of disaster management core competency (24 items) by Likert 5-point scale. Data were analyzed using t-test, ANOVA, Pearson's correlation coefficient using IBM SPSS 24.0. Results: The seriousness of personal disaster was 4.02 points and the importance of disaster-related education was 4.28 points. The importance to core competency of disaster management was 4.39 points and the ability to perform core competency was 3.58 points. The seriousness of personal disaster and the importance of disaster-related education were positively correlated (r=.600, p=.000). The importance and ability to perform core competency were positively correlated (r=.389, p=.000). Conclusion: It is necessary to strengthen core competency of disaster management in paramedics who are the first defense line of disaster.

Developing the Core Modules of for Viz-Platform for Supporting Public Service in the City (도시의 공공서비스 제공을 위한 시각화 플랫폼의 핵심모듈 개발)

  • Kim, Mi-Yun
    • Journal of Korea Multimedia Society
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    • v.18 no.9
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    • pp.1131-1139
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    • 2015
  • The purpose of this research is creating the visualization platform of the user interface to make able to be provide the demanded service while users communication with surrounding space in a smart city environment. This comes from the latest enhanced interface technology and social media, and it uses the shares information to support the proper interface environment according to a life style and spatial properties. "EzCity" which is the user interface platform suggested in this research, can control the enormous amount of public data for the smart city. The core module of user platform is made up with Public data module, Interface module, Visualization module and Service module. The role of this platform is to be provide "Geo-Intelligent Interface Service" for space users to access the data in easier and more practical interface environment. This reinforces the visualization process for data collecting, systematization, visualization and providing service. Also this will be expected to be the base to solve the problem which complexity and rapidly increasing amount of data.

Service Function Chaining Architecture for Distributed 5G Mobile Core Networks (분산 모바일 코어기반 5G 네트워크에서의 Service Function Chaining 적용구조)

  • Sun, Kyoungjae;Kim, Younghan
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.41 no.12
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    • pp.1914-1924
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    • 2016
  • In this paper, considering virtualized Evolved Packet Core(vEPC) network for 5G mobile network, we propose architecture for supporting Service Function Chaining(SFC) in 5G mobile network. Using SFC in 5G network, dynamic path configuration and providing network services based on subscriber and traffic information. SFC technology provides logical ordered set of network functions and delivers packet through providing logical path over the physical network. Based on the perspective of 5G core network in distributed manner, we design hierarchical SFC architecture to manage SFC for global path including vEPC and SGi-LAN network, and internal path between virtualized network functions in each cloud. In this paper, we define architecture and call flow for establishing data path using SFC. Finally, we design testbed architecture for real implementation based on open source software.

An Approach to Developing Service Descriptions Based on Product Line (프로덕트 라인 기반 서비스 명세 생성 방법)

  • Park, Joon-Seok;Moon, Mi-Kyeong;Yeom, Keun-Hyuk
    • The KIPS Transactions:PartD
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    • v.16D no.5
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    • pp.747-754
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    • 2009
  • Software product line engineering is an approach to creating core assets by systematically exploits common that can be highly reusableand different characteristics in related system families that is domain. By adapting this approachin object and component paradigm, software productivity is extended. Recently, Software development paradigm is changed to service oriented paradigm which is using services that are core assets. Therefore, to develop service oriented software more flexible, systematic and to enhance business agility about business changes, we need adaptation of product line to creation of services that are core assets. In this paper, we propose an approach to create and specify domain service through combine of product line and service oriented paradigm. Domain service explicitly specifies commonality and variability by domain service common/optional property variability, operation type variability, message type variability. By using this approach, it can support efficient and flexible service oriented development by producing various services through customization of domain service for the purpose.

Analysis of the Experiences and Attitudes of Elementary School Pre-service Teachers on Entrepreneurship Education and Core Competencies of Entrepreneurship (초등 예비교사의 창업가정신 교육에 대한 경험 및 태도와 창업가정신 핵심역량 분석)

  • Lee, Soo-Young
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.16 no.1
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    • pp.99-111
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    • 2021
  • The purpose of this study is to examine the experiences and attitudes of elementary pre-service teachers, the level of entrepreneurship core competencies, and to analyze differences in entrepreneurship core competencies by grade, gender, and attitude. To this end, 208 elementary pre-service teachers who responded to the online questionnaire surveyed their experience, attitudes, perceptions, entrepreneurship attempts, and entrepreneurship core competency levels. As a result, pre-service teachers had a low level of understanding and direct participation in entrepreneurship education, the need for entrepreneurship education for elementary school students and teachers was high. The average of the value-creation competency group consisting of innovation, social value orientation, and change agility was relatively lower than the challenge, group creativity, and self-directed competency group. The difference of the entrepreneurship core competency level between the grades was not significant, and female students' competency levels were statistically significantly higher than male students. In addition, the average of the four core competencies of entrepreneurship in the group that recognizes the importance of entrepreneurship as essential competencies was statistically higher than that of their counterparts. Based on the results of this study, the implications for the design and development of a program for enhancing entrepreneurship competency for elementary school pre-service teachers were presented.

Does the Understanding of Core Competencies Matter to IT Outsourcing Performance? (기업의 핵심역량이 IT 아웃소싱 성과에 직접적인 관련이 있을 것인가?)

  • Kim, Young-Jin;Nam, Ki-Chan;Koo, Chul-Mo
    • Journal of the Korean Operations Research and Management Science Society
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    • v.32 no.3
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    • pp.97-114
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    • 2007
  • IT outsourcing providers has been expanded from a single functional system to the entire IT service to gain sustainable competitiveness. This new trend of IT outsourcing need outsourcing management capability based on a firm's core capacity. Hiring external IT service providers to manage part or all of its information-related services helps a firm focus on its core business and provides better services to its clients, thus obtaining sustainable competitive advantage. This research investigates the major factors that determine the level of a particular firm's success at IT outsourcing. Based on process innovation and core-competency theories, we identify three significant components of a firm's IT outsourcing management method (ITOMM): level of core-competency-based management, maturity of outsourced tasks, and maturity of outsourcing management. Comprehensive data collection was conducted through an outsourcing association. The survey data were analyzed using a structural analysis method. Maturity of outsourced tasks and maturity of outsourcing management were found to affect project performance directly, while level of core-competency-based management only indirectly impacted project performance through its positive impact on the other two ITOMM components.

An Analysis of Core Competence of Pre-construction Service of the Making Inroads into Oversea Construction Market (*for the Entry in the International Construction Business) (해외건설시장 진출을 위한 건설사의 Pre-construction Service 핵심역량 분석)

  • Byun, Il-Woo;Kim, Ye-Sang
    • Korean Journal of Construction Engineering and Management
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    • v.13 no.2
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    • pp.80-90
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    • 2012
  • In 2011, the overall construction markets in KOREA are highly depressed due to decreases in orders of domestic construction markets in both private and public field. Also, we are losing competitive advantages over Chinese and Indian companies owing to the market shares on plant construction projects excessively. It is recognizable, under the circumstances that we are in interior position on high value technique to other advanced countries, that the orders of mega building and plant construction projects tend to be placed through the" Pre-construction Service", the importance of which has been emphasized domestically and internationally in recent time. However, current domestic construction companies show scarcity in understanding the general idea of the Pre-construction Service and fail in building proper structure of it. It is obvious that they cannot have any competent strategy to deal with Pre-construction Service. The Purpose of this paper is to analyze the core competence throughout preconstruction phase and, and make up for the weakness in the current pre-construction service process.