• Journal of International Academy of Physical Therapy Research
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• v.11 no.3
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• pp.2126-2134
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• 2020

Background: Therapeutic climbing training, which originated in Germany, is a wall-hanging rock climbing-based therapy to increase the body's coordination through movement of the upper and lower limbs against gravity. However, there are no studies examining the effectiveness of therapeutic climbing training to treat balance and gait ability in patients with chronic stroke. Objectives: To investigate therapeutic climbing training program on balance and gait in patients with chronic stroke. Design: Pretest-posttest control group design. Methods: Fourteen patients with chronic hemiplegic stroke participated. Participants were randomized into the therapeutic climbing training group (TCTG, n=7) and the standard rehabilitation program group (SRPG, n=7) group. All subjects participated in the same standard rehabilitation program consisting of 60 minutes 5 times a week for 6 weeks. TCTG participated additionally in the therapeutic climbing program consisting of 30 minutes sessions 3 times a week for the same 6 weeks. Berg balance scale (BBS), Gaitview Measure, Timed up and go test (TUG) were measured. Results: In the TCTG, revealed a statistical difference in BBS between the groups; in the difference of plantar pressure ratio in the static standing position revealed a statistical difference between the groups after training; the balance ability in the one-leg standing tests increased significantly; the time in TUG decreased significantly after training in both groups; The changes in the difference of dynamic plantar pressure ratio were reduced significantly in the TCTG. Conclusion: Therapeutic climbing training contribute to improve balance and walking function in patients with chronic stroke.

• Phonetics and Speech Sciences
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• v.3 no.1
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• pp.135-143
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• 2011

This study evaluated the respiratory capacity of spastic cerebral palsy children who were grouped by GMFCS (Gross Motor Function Classification System) levels and identified the acoustic characteristics of three different types of Korean stops (stop consonants) which are needed for the temporal coordination of larynx and supra-larynx, in these children. Thirty-two children with dysarthria due to spastic cerebral palsy were divided into two subgroups: 14 children classified at GMFCS levels I~III were placed in Group 1 and 18 classified at GMFCS levels IV~V were placed in Group 11, and 18 children with normal speech were selected and placed in the control group. /a/ pronged phonation (sustained vowel /a/) and nine Korean VCV syllables were used. Examined acoustic characteristics were maximum phonation time (MPT) and closure duration and aspiration duration. The results were as follows: 1) The MPTs of the cerebral palsy (CP) groups, both Group I and Group II, were significantly shorter than those of the normal group. 2) The closure durations of the two CP groups were longer than those of the normal group for all 9 target syllables. 3) The aspiration durations of the two CP groups were longer than those of the normal group. 4) The closure duration of the normal and CP Group I was significantly different among tense, aspirated, and lax. However, the CP Group II was different from normal. 5) The aspiration duration of the normal and CP Group I was significantly different among aspirated, tense, and lax. However, the CP Group II was different from normal. 6) The place of articulation influenced less than the manner of articulation on closure and aspiration duration.

• Molecules and Cells
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• v.21 no.2
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• pp.251-260
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• 2006

During mitosis, genomic integrity is maintained by the proper coordination of anaphase entry and mitotic exit via mitotic checkpoints. In budding yeast, mitotic exit is controlled by a regulatory cascade called the mitotic exit network (MEN). The MEN is regulated by a small GTPase, Tem1p, which in turn is controlled by a two-component GAP, Bfa1p-Bub2p. Recent results suggested that phosphorylation of Bfa1p by the polorelated kinase Cdc5p is also required for triggering mitotic exit, since it decreases the GAP activity of Bfa1p-Bub2p. However, the dispensability of GEF Lte1p for mitotic exit has raised questions about regulation of the MEN by the GTPase activity of Tem1p. We isolated a Bfa1p mutant, $Bfa1p^{E438K}$, whose overexpression only partially induced anaphase arrest. The molecular and biochemical functions of $Bfa1p^{E438K}$ are similar to those of wild type Bfa1p, except for decreased GAP activity. Interestingly, in $BFA1^{E438K}$ cells, the MEN could be regulated with nearly wild type kinetics at physiological temperature, as well as in response to various checkpoint-activating signals, but the cells were more sensitive to spindle damage than wild type. These results suggest that the GAP activity of Bfa1p-Bub2p is responsible for the mitotic arrest caused by spindle damage and Bfa1p overproduction. In addition, the viability of cdc5-2 ${\Delta}bfa1 $ cells was not reduced by $BFA1^{E438K}$, suggesting that Cdc5p also regulates Bfa1p to activate mitotic exit by other mechanism(s), besides phosphorylation.

• Journal of the Korean Society of Fashion and Beauty
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• v.2 no.3 s.3
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• pp.36-43
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• 2004

This is a research on the effect of formula containing of vitamin A and vitamin E(Frie of oil, Wlter Bouhon GmBH, Germany) on the strech mark. The participants of this study were 20 women at the age of early 20s through middle 20s, who had strech marks that had been over 1 year at the minimum and at less than 5 years at the maximum. Formula containing of vitamin A and vitamin E was applied with typical massage to strech marks for 4 months and twice per day. Improvement resulting from the application was evaluated through observation with the naked eye, questionnaire survey, and the equipment used was DermaScan C Ver3(Cortex Technology, Denmark). The experiment showed that parts cared with formula containing of vitamin A and vitamin E had less strech marks than those control site(treated with jojoba oil).In around 2 months since the use of the formula containing of vitamin A and vitamin E, the tensile of the skin increased and deep wrinkles on the chapped surface became unclear, and in around 4 months the tensile force again decreased and the resilience of the skin increased, and the ultrasonic image showed the decrease of echo pore-zone, which indicates the degree of tissue damage. According to the result of the questionnaire survey, strech marks of less than red strech marks of primary stage were improved more quickly than white strech marks and all participants appeared to experience improvement. The result shows that if this formula is used continuously over 4 months, it reduces strech marks and increase the resilience of the skin. It is considered necessary to continue objective measuring and research concerning strech marks.

• Journal of Communications and Networks
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• v.14 no.5
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• pp.524-532
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• 2012

In this paper, we present the performance evaluation of the reliable cooperative media access control (RCO-MAC) protocol, which has been proposed in [1] by us in order to enhance system throughput in bad wireless channel environments. The performance of this protocol is evaluated with computer simulation as well as mathematical analysis in this paper. The system throughput, two types of average delays, average channel access delay, and average system delay, which includes the queuing delay in the buffer, are used as performance metrics. In addition, two different traffic models are used for performance evaluation: The saturated traffic model for computing system throughput and average channel access delay, and the exponential data generation model for calculating average system delay. The numerical results show that the RCO-MAC protocol proposed by us provides over 20% more system throughput than the relay distributed coordination function (rDCF) scheme. The numerical results show that the RCO-MAC protocol provides a slightly higher average channel access delay over a greater number of source nodes than the rDCF. This is because a greater number of source nodes provide more opportunities for cooperative request to send (CRTS) frame collisions and because the value of the related retransmission timer is greater in the RCO-MAC protocol than in the rDCF protocol. The numerical results also confirm that the RCO-MAC protocol provides better average system delay over the whole gamut of the number of source nodes than the rDCF protocol.

• Korean Journal of Applied Biomechanics
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• v.30 no.2
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• pp.185-195
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• 2020

Objective: The purpose of this study was to identify recent domestic and international research trends regarding shoes carried out in biomechanics field and to suggest the direction of shoe research later. Method: To achieve this goal of research, the Web of Science, Scopus, PubMed, Korea Education and Research Information Service and Korean Citation Index were searched to identify trends in 64 domestic and international research. Also, classified into the interaction of the human body, usability evaluation of functional shoes, smart shoe development research, and suggested the following are the suggestions for future research directions. Conclusion: A study for the coordination of muscle activity, control of motion and prevention of injury should be sought by developing shoes of eco-friendly materials, and scientific evidence such as physical aspects, materials, floor shapes and friction should be supported. Second, a study on elite athletes in various sports is needed based on functional shoes using new materials to improve their performance along with cooperation in muscle activities and prevention of injury. Third, various information and energy production are possible in real time through human behavioral information, and the application of Human Machine Interface (HMI) technology through shoe-sensor-human interaction should be explored.

• The Journal of Korean Physical Therapy
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• v.23 no.1
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• pp.7-11
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• 2011

Purpose: Driving is essential to maintain independent living status in modern times. Many patients want to know when they can drive again, but it's only possible if they have the ability to control lower extremity muscles. In this study, we compared the effects of velocity on onset time of lower extremity muscles during driving tasks. Methods: Twelve participants (5 male, 7 female) were enrolled. EMGs were used to test the onset time of lower extremity muscles; tibialis anterior, soleus, rectus femoris. To analyze the data, we used two way ANOVA. Results: According to brake pedaling velocity, there was a significant difference in brake response time (p<0.05). Further, when comparing the lower extremity muscles, there was a significant difference in onset time (p<0.05). The order of muscle recruitment was tibialis anterior, rectus femoris, and soleus for achieving maximal velocity, but the order was rectus femoris, tibialis anterior, soleus for achieving submaximal velocity. Conclusion: Brake pedaling velocity has significant effects on onset time of muscle contractions in the lower extremities. We suggested that a future study needs more subjects and more detailed research such as evaluat-ions of visuo-motor coordination and fine motor dexterity.

• Journal of The Korean Society of Grassland and Forage Science
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• v.34 no.1
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• pp.15-20
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• 2014

To investigate lignification process and its physiological significance under water-deficit condition, the responses of peroxidases, polyphenol oxidase (PPO) and phenylalanine ammonia-lyase (PAL) in relation to leaf water status to the short term of water deficit treatment in the leaves with different maturities in forage rape were measured. The significant decrease in relative water content (RWC) and leaf osmotic potential (${\Psi}{\pi}$) were apparent after 5 d of water-deficit treatment. The activity of guaiacol peroxidase (GPOD), ascorbate peroxidase (APOD), coniferyl alcohol peroxidase (CPOD), and syringaldazine peroxidase (SPOD) was depressed especially in middle and old leaves when compared with that of control leaves. On the other hand, in young leaves, a significant increase in CPOD (+34%) and SPOD (+24%) activity as affected by water-deficit treatment was apparent. The activation of PAL and PPO was observed in middle and old leaves for PAL and in young and middle leaves for PPO. These results suggest that peroxidases in middle and old leaves did not involve in lignification under mild water-deficit stress, whereas CPOD and SPOD in young leaves participate in lignification by a coordination with PAL and PPO to incorporate phenol and lignin into the cell walls.

• Journal of Information Processing Systems
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• v.13 no.5
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• pp.1229-1242
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• 2017

In this paper, an interference aware distributed multi-channel MAC (IDMMAC) protocol is proposed for wireless sensor and actor networks (WSANs). The WSAN consists of a huge number of sensors and ample amount of actors. Hence, in the IDMMAC protocol a lightweight channel selection mechanism is proposed to enhance the sensor's lifetime. The IDMMAC protocol divides the beacon interval into two phases (i.e., the ad-hoc traffic indication message (ATIM) window phase and data transmission phase). When a sensor wants to transmit event information to the actor, it negotiates the maximum packet reception ratio (PRR) and the capacity channel in the ATIM window with its 1-hop sensors. The channel negotiation takes place via a control channel. To improve the packet delivery ratio of the IDMMAC protocol, each actor selects a backup cluster head (BCH) from its cluster members. The BCH is elected based on its residual energy and node degree. The BCH selection phase takes place whenever an actor wants to perform actions in the event area or it leaves the cluster to help a neighbor actor. Furthermore, an interference and throughput aware multi-channel MAC protocol is also proposed for actor-actor coordination. An actor selects a minimum interference and maximum throughput channel among the available channels to communicate with the destination actor. The performance of the proposed IDMMAC protocol is analyzed using standard network parameters, such as packet delivery ratio, end-to-end delay, and energy dissipation, in the network. The obtained simulation results indicate that the IDMMAC protocol performs well compared to the existing MAC protocols.

• Journal of Korean society of Dental Hygiene
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• v.19 no.2
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• pp.173-181
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• 2019

Objectives: The resin infiltration technique is a promising alternative therapy for arresting the early dental caries. However, there are very few reports on the safety and biocompatibility of this technique. We evaluated various properties of resin infiltrant (RI) based on a triethylene glycol dimethacrylate (TEGDMA).The water sorption (Wsp) and water solubility (Wsl) was assessed. Additionally, the cytotoxicity of RI against both animal and human fibroblast cell lines was investigated. Methods: The RI of the $Icon^{(R)}$, the first product developed for resin infiltration, is mainly composed of TEGDMA in the resin matrix. The Wsp and Wsl for the RI were measured in accordance with ISO 4049 specifications. Fourier-transform infrared spectroscopy (FTIR) was used for analyzing the polymerization before and after curing of RI. The cytotoxicity of RI against the mouse fibroblasts (L929) and human gingival fibroblasts (hTERT-hNOF) was evaluated using MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay and the data were analyzed using one-way analysis of variance. Results: Wsp and Wsl of the RI specimens were $53.37{\mu}g/mm^3$ and $10.6{\mu}g/mm^3$, respectively. FTIR analysis revealed a slightly higher degree of curing with longer irradiation time. The degree of conversion for RI was high (80.9%) after 40 seconds of light curing. There was a significant decrease in the viability of L929 and hTERT-hNOF cells at RI extraction solution concentrations above 50%, respectively, compared to that in the negative control (p< 0.05). Conclusions: Even though the RI exhibited positive effect on the early prevention of dental caries, the clinicians should also consider the toxicity of RI on periodontal tissues.