• Journal of Dairy Science and Biotechnology
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• v.35 no.1
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• pp.39-45
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• 2017

The market for lactose-hydrolyzed milk is growing due to an increased awareness of lactose intolerance, and increased market interest for modified milk with health claims. The aim of this study was to compare the quality characteristics of 2% lactose-hydrolyzed milk with its lactose hydrolysis rate, with the goal of applying the method to dairy product monitoring in the future. We observed that the freezing point of milk significantly decreased with increasing lactose hydrolysis rate. A linear relationship was found between lactose concentration and freezing point, following the equation (y=-50.416x + 767.91). However, no significant changes were observed in other physicochemical properties of the milk (pH, titratable acidity, total solids and color) (p<0.05). In conclusion, we could predict the residual lactose content quickly and easily in 2% low fat milk by measuring its freezing point. This could represent an easy means for assessing the lactose hydrolysis rate of dairy products.

• Journal of the Korea Society of Computer and Information
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• v.16 no.12
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• pp.23-31
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• 2011

The simple bacteria cooperative optimization (sBCO) algorithm that we developed as one of optimization algorithms has shown relatively good performances, but their performances were limited by step-by-step movement of individuals at a time. In order to solve this problem, we proposed a new method that assigned a speed to each individual according to its rank and it was confirmed that it improved the performances of sBCO in some degree. In addition to the assigning of speed to the individuals, we employed a new mutation operation that most existing evolutionary algorithms used in order to enhance the performances of sBCO in this paper. A specific percent of bad individuals are mutated within an area that is proportion to the rank of the individual in the mutation operation. That is, Gaussian noise of large standard deviation is added as the fitness of individuals is low. From this, the probability that the individuals with lower ranks can be located far from its parent will be increased. This causes that the probability of falling into local optimum areas is decreased and the probability of fast escaping the local optimum areas is increased. From experimental results with four function optimization problems, we showed that the performances of sBCO with mutation operation and individual speed were increased. If the optimization function is quite complex, however, the performances are not always better. We should devise a new method for solving this problem as a further work.

• The Korea Journal of Herbology
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• v.31 no.4
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• pp.101-109
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• 2016

Objectives : HT070 is a mixture of herbal extracts from root of Scutellaria baicalensis and stem bark of Eleutherococcus senticosus , which have long been used for stroke therapy in traditional Korean Medicine. The purpose of this study was to investigate the neuroprotective effects of HT070 on global cerebral ischemia and its potential mechanisms.Methods : Transient global cerebral ischemia was produced by 10 min of four-vessel occlusion (4-VO) in male Wistar rats. HT070 was administered orally at a dosage of 200 mg/kg twice at 0 and 90 min after reperfusion. Hippocampal neuronal damage was measured 7 days after reperfusion. To explore the potential mechanisms, we used hydrogen peroxide (H₂O₂)-induced rat pheochromocytoma (PC12) cells as an in vitro model. PC12 cells were pretreated with HT070 for 1 h and then exposed to 100 μM H₂O₂ for 6 h in the presence of HT070. Cell viability was measured by MTT assay and the mRNA expression of Bax, Bcl-2, iNOS and COX-2 were measured by quantitative RT-PCR.Results : Oral administration of HT070 at a dose of 200 mg/kg significantly reduced neuronal death in the hippocampal CA1 region by 13.4% as compared to the vehicle-treated group. HT070 increased cell viability, reversed the down-regulated Bcl-2 mRNA level, and suppressed the up-regulated mRNA expressions of Bax, iNOS, and COX-2 in H₂O₂-treated PC12 cells.Conclusions : HT070 protects against delayed neuronal death after global cerebral ischemia and its neuroprotection properties might be attributed to the inhibition of mitochondrial apoptosis and ROS-generating enzymes.

• Korean Journal of Food Science and Technology
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• v.50 no.2
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• pp.198-202
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• 2018

The present study aimed to investigate the effect of germination and temperature on the antioxidant activity of coffee. Green beans were germinated at 20 and $40^{\circ}C$. Germinated green beans were dried and roasted. Ground coffee was brewed at $90^{\circ}C$ for 5 min. Coffee samples were analyzed for antioxidant compounds and for its antioxidant activity. The total polyphenol content (TPC) and total flavonoid content (TFC) in coffee brewed with coffee beans germinated at $20^{\circ}C$ (CG20) were significantly higher than those in coffee brewed with non-germinated coffee beans (CNG). The same tendency was observed on 2,2-diphenyl-1-picrylhydrazyl and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid) radical scavenging assays. TPC and TFC of coffee brewed with germinated coffee beans decreased with an increase in germination temperature from 20 to $40^{\circ}C$. In conclusion, germination of coffee beans contributes to an increase in its antioxidant activity. However, setting the appropriate temperature for germination is an important factor in determining the antioxidant activity of coffee.

• Journal of the Korean Society for Precision Engineering
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• v.30 no.1
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• pp.11-17
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• 2013

'Multi-scale mass-deployable cooperative robots' is a next generation robotics paradigm where a large number of robots that vary in size cooperate in a hierarchical fashion to collect information in various environments. While this paradigm can exhibit the effective solution for exploration of the wide area consisting of various types of terrain, its technical maturity is still in its infant state and many technical hurdles should be resolved to realize this paradigm. In this paper, we propose to develop new design and manufacturing methodologies for the multi-scale mass-deployable cooperative robots. In doing so, we present various fundamental technologies in four different research fields. (1) Adaptable design methods consist of compliant mechanisms and hierarchical structures which provide robots with a unified way to overcome various and irregular terrains. (2) Soft composite materials realize the compliancy in these structures. (3) Multi-scale integrative manufacturing techniques are convergence of traditional methods for producing various sized robots assembled by such materials. Finally, (4) the control and communication techniques for the massive swarm robot systems enable multiple functionally simple robots to accomplish the complex job by effective job distribution.

• Wind and Structures
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• v.9 no.4
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• pp.331-344
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• 2006

The cable-stayed-suspension hybrid bridge is a cooperative system developed from the traditional cable-stayed and suspension bridges, and takes some advantages of the two bridge systems. It is also becoming a competitive design alternative for some long and super long-span bridges. But due to its great flexibility, the flutter stability plays an important role in the design and construction of this bridge system. Considering the geometric nonlinearity of bridge structures and the effects of nonlinear wind-structure interaction, method and its solution procedure of three-dimensional nonlinear flutter stability analysis are firstly presented. Parametric analyses on the flutter stability of a cable-stayed-suspension hybrid bridge with main span of 1400 meters are then conducted by nonlinear flutter stability analysis, some design parameters that significantly influence the flutter stability are pointed out, and the favorable structural system of the bridge is also discussed based on the wind stability.

• Journal of Korean Library and Information Science Society
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• v.39 no.2
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• pp.147-167
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• 2008

The purpose of the research is to 4ind out its problems and to suggest its solution by investigating and analyzing the present condition of the Virtual Reference Shelves establishment in Chinese university libraries. To achieve the goal, this study establishes theoretical foundations for virtual reference shelves. The evaluation standard was set up on the basis of this theoretical foundation. The 38 university libraries, which had been selected in 985 Project were analyzed by this evaluation standard. The results are used to justify the cooperative establishment for virtual reference shelves.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.32 no.3
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• pp.159-167
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• 2009

In this paper, we consider a single-vendor single-buyer supply chain problem where a single vendor orders raw materials from its supplier, then using its manufacturing processes converts the raw materials to finished goods in order to deliver finished goods to a single buyer for effective implementation of Just-In-Time Purchasing. An integrated lot-splitting model of facilitating multiple shipments in small lots between buyer and supplier is developed in a JIT Purchasing environment. Also, an iterative heuristic solution procedure is developed to find the order quantity for finished goods and raw materials, and number of shipments between buyer and supplier. We show by numerical example that when the integrated policy is adopted by both vendor and buyer in a cooperative manner, both parties can benefit.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.9 no.1
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• pp.19-26
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• 2010

In this paper, we propose an efficient decision rule in order to get better chance to detect the unused spectrum assigned to a licensed user and improve reliability of spectrum sensing performance. Each secondary user receives the signals from the licensed user. And the resulting signals input to an energy detector. Then, each sensing result is combined and used to make a decision whether the primary user is present at the licensed spectrum band or not. In order to make the reliable decision, we apply an efficient decision rule that is called as a majority rule in this paper. The simulation results show that spectrum sensing performance with the proposed decision rule is more reasonable and efficient than that with conventional decision rules.

• Journal of the Korean Institute of Telematics and Electronics S
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• v.34S no.8
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• pp.56-64
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• 1997

In distributed autonomous robotic systems, each robot must behaves by itself according to the its states and environements, and if necessary, must cooperates with other orbots in order to carray out a given task. Therefore it is essential that each robot has both learning and evolution ability to adapt the dynamic environments. In this paper, the new learning and evolution method based on reinforement learning having delayed reward ability and distributed genectic algorithms is proposed for behavior learning and evolution of collective autonomous mobile robots. Reinforement learning having delayed reward is still useful even though when there is no immediate reward. And by distributed genetic algorithm exchanging the chromosome acquired under different environments by communication each robot can improve its behavior ability. Specially, in order to improve the perfodrmance of evolution, selective crossover using the characteristic of reinforcement learning is adopted in this paper, we verify the effectiveness of the proposed method by applying it to cooperative search problem.