• Journal of Chest Surgery
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• 제30권7호
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• pp.733-738
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• 1997

순차적 양측 폐이식수술은 수술시 및 수술후 합병증이 매우 다양하며 수술후 결과가 매우 불량하다. 저자 등은 양측 폐 이식수술후의 혈역학적 변화를 연구관찰하고자 하였으며 수술후 발생할 수 있는 거부반 응을 예방하기 위하여 양측 폐재식수술을 선택,시행하였으며 폐동맥의 뒤틀림이나 협착, 좌심방내의 혈전발 생 등을 예방하기 위하여 폐동맥 및 좌심방 부위를 혈관감자로 폐쇄시킨 후 폐측 폐동맥의 전면을 절단하였고, 폐측 상하 폐정맥부위 좌심방 전면을 절단한 후 1시간동안 폐동맥 절단부위를 통해 PGEI이 함유된 I-C 용액을 주입하였고 1시간동안 I-C용액이 함유된 거즈를 이용하여 냉각을 유지하였다. 다시 5-0 prolene을 이 용하여 봉합하였다. 좌심방을 봉합할 때 내면이 외 전되게끔 everted suture 방법으로 봉합하였다. 주기관지는 완전 절단후 telescope방법으코 단단문합하였으며 폐재식 수술전후의 동맥혈 산소가스치, 대퇴동맥 및 폐동맥 압을 측정하여 비교하였으며 수술전후의 뚜렷한 혈역학적 변화는 없었다. 절단 결찰된 폐는 PcEl이 함유된 I-c용액을 폐동맥으로 4o cmHlo 압력으로 Is ~h입분의 속도로 총량이 70 mfg되도록 주입하\ulcorner으며 그후 1시간동안 냉각된 I-C용액이 함유된 거즈를 이용하여 절단된 폐를 감싸서 냉각저류보관하여 허혈성 손상을 예방함으로써 수술수기에 대한 합병증이 없는한 양측 폐 이식수술후 성 적은 양호할 것으로 생각된다.

• 대한한의학원전학회지
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• 제22권4호
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• pp.221-239
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• 2009

Background: The recent outbreak of the novel strain of influenza A (H1N1) virus has raised a global concern of the future risk of pandemic. Traditional Korean Medicine(TKM) has been combatting against contagious diseases and developed its own particular and efficient way in treating those diseases. Objectives: Provide a distinctive and effective TKM method in understanding the principles of treatment, prevention, and contraindications against influenza A through case histories. Method: We revised case histories of eminent doctors of Ming and Qing dynasties according to their clinical manifestations similar to those of influenza A. We also verified prescriptions of the "Dong-uibogam(東醫寶鑑)" through examining clinical practices of China today. Results: 1. The subtypes of Warm disease; Wind Warmth and Pestilence has the most similar clinical manifestation in comparison to Influenza A. Specifying these terms is important in recognizing and classifying various diseases under the name of Warm disease. 2. TKM considered not only external factors but also individual factors like general condition, diet, emotion, constitutional types, etc in the treatment of febrile diseases. 3. TKM developed a new way in the treatment of contagious diseases. considering the characteristics of each pathogen. TKM described the Warm pathogen being light as a feather, which enters through the nose, principally affecting the Lung. Therefore, they emphasized treatment with Pungent Sweet Cooling Moistening[辛甘凉潤] method. 4. As the conservation of fluid and humor is the primordial concern in the treatment of Warm disease, they restricted release of the exterior with pungent-warm and purgation method. The purgation methods was used exclusively to decrease fever and preserve fluid and humor. 5. The only differentiating characteristics of Influenza A with seasonal influenza are vomiting and diarrhea. Case research revealed the possibility of these manifestations to be a mechanism of restoration. 6. TKM provides alimento prevention method like Mint Pear Porridge, mung bean, and etc also combination of herbal medicine. Also emphasized in the conservation of essence for the prevention of contagious diseases. Conclusions: TKM developed its unique way in understanding the pathogenesis, diagnosis, treatment, and prevention of contagious diseases and formed its independent scheme of Warm Disease. This knowledge in febrile contagious disease is relevant today in providing diverse treatment and prevention for influenza A.

• Clinical and Experimental Reproductive Medicine
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• 제38권4호
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• pp.203-209
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• 2011

Objective: This study was performed to compare the efficiency of slow freezing and vitrification based on survival, development to blastocysts, and cell numbers of blastocysts. Changes in embryonic gene expression in fresh and frozen-thawed embryos were also examined. Methods: Eight-cell stage embryos were collected from superovulated female BDF1 mice. The collected embryos were randomly divided into three groups. One group was maintained as fresh controls (n=42), one was frozen by slow freezing (n=43), and one was cooled by vitrification (n=43). After thawing or cooling, survival rates, development to blastocyst, and cell numbers and inner cell mass (ICM) cell numbers of blastocysts were compared with those of the control group. The expressions of eight genes ($Rbm3$, $Birc5$, $Sod1$, $Sod2$, $Cirbp$, $Caspase3$, $Trp53$, $Hsp70.1$) were examined by real time-quantitative polymerase chain reaction in the fresh and frozen-thawed embryos. Results: There were no significant differences in the slow freezing and vitrification groups' survival rate after thawing (88.4% vs. 88.4%), development to blastocyst (100% vs. 97.4%), cell numbers ($107.0{\pm}21.0$ vs. $115.0{\pm}19.7$), or ICM cell numbers of blastocysts ($11.3{\pm}5.2$ vs. $11.1{\pm}3.7$). Cell numbers of blastocysts were significantly ($p$ <0.05) lower in the frozen-thawed embryos than the fresh embryos. There were no significant differences in the slow freezing and the vitrification groups' expressions of the eight genes. The expressions of $CirbP$ and $Hsp70.1$ were higher in the frozen-thawed embryos than in the fresh embryos but there were no significant differences. Conclusion: These results suggest that there were no significant differences between embryos that underwent slow freezing and vitrification.

• 전산구조공학
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• 제10권3호
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• pp.175-184
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• 1997

본 논문의 목적은 부등침하를 받는 회전 쉘의 최대 응답과 표준편차와의 관계를 규명하는 것이다. 이를 위해 표준편차에 대한 최대응답의 비(.eta.)및 그 개략값(.eta./sub apr/)를 통계적 수법으로 조사하였다. 또한 탁월차수(predoninant harmonic number)의 함수로 표현되는 .eta./sub apr/을 구하기 위한 식을 제안하였다. 한편 침하는 Fourier급수로 표시하였다. 이때 각 항은 2개의 계수를 포함하게 되는데 하나는 진폭 스펙트럼이고 다른 하나는 위상각이다. 여기서는 위상각은 확률변수로, 진폭은 확정값으로 가정하였다. 해석에서는 .eta., .eta./sub apr/의 특성을 조사하기 위해 2가지 type의 진폭 스펙트럼을 실측데이터를 근거로 설정한 후, 각 type에 대해 100 sample씩의 위상각을 가정하여 사용하였다. .eta.,.eta./sub apr/은 응답의 종류, 쉘의 위치 그리고 진폭 스텍트럼의 type에 상관없이 거의 일정한 값으로 분포하며 그 값은 2.0에서 2.5사이의 값이 된다. 또한 .eta./sub apr/의 값은 .eta.의 값과 거의 비슷하지만 약간 큰 값으로 나타났다. 결론으로 부등침하를 받는 회전 쉘의 최대 응답은 표준편차의 .eta./sub apr/(약 2.5)배 임을 밝히고 있다.

• 한국환경보건학회지
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• 제39권2호
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• pp.166-177
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• 2013

Objectives: The genus Legionella is common in aquatic environments. Some species of Legionella are recognized as potential opportunistic pathogens for human, notably Legionella pneumophila that causes, Legionellosis. Thus, we investigated the contamination of Legionella pneumophila on water supply systems in Seoul, including cooling towers, public baths, hospitals and fountains. Methods: The existence of 16S rRNA and mip gene of L. pneumophila was confirmed in the genome of the isolated strains by PCR. Results: During the summer season of 2010 and 2011, Legionella pneumophila were detected from 163 samples (21.1%) out of 772 samples collected. Among the 163 strains of L. pneumophila, eighty one isolates belonged to serogroup 1 (57.4%), 23 isolates were serogroup 5 (16.3%), 21 isolates were serogroup 6 (14.9%), 8 isolates were serogroup 2 (5.79%), and 8 isolates were identified in serogroup 3 (5.7%). Through PFGE (pulsed-field gel electrophoresis) analysis using Sfi I, genetic types of L. pneumophila were classified into five (A to E) patterns by the band similarity with excess of 70% from public baths. Conclusions: The PFGE patterns of the serotypes showed a tendency for diversity of L. pneumophila. Our results suggest the existence of serological and genetic diversity among the L. pneumophila isolates.

• 생물환경조절학회지
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• 제24권1호
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• pp.34-38
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• 2015

본 실험은 광파장 선택형 차광제와 이류체 포그시스템을 이용하여 고온기 시설내 고온과 건조문제를 해소할 수 있는 적정 냉각법을 구명하기 위하여 수행되었다. 실험처리는 차광제와 이류체 포그시스템을 설치하지 않은 대조구(Non), 이류체 포그시스템만 설치하여 작동한 처리(Fog), 차광제만 도포한 처리(Coat), 외부에 차광제를 도포하고 내부에 이류체 포그시스템을 작동한 처리(F&C) 등이었다. 유입 일사량(열량)은 Non, Fog, Coat, F&C 순으로 많았다. 시설내 기온을 낮추는 방법으로는 이류체 포그시스템이 더 효과적이었다. 또한 이류체 포그시스템을 처리하면 상대습도도 적절히 조절할 수 있었다. 작물의 품온은 다른 처리구에 비해 대조구에서 약 $6^{\circ}C$ 이상 높았다. 연구결과, 고온기 시설내 광, 온도, 상대습도 환경조절에 가장 효과적인 방법은 이류체 포그시스템과 차광제 도포를 함께 하는 것이나, 효과 및 경제성을 함께 고려한다면 이류체 포그시스템을 활용하는 것이 가장 좋은 것으로 판단된다. 그러나 단동하우스의 경우에는 구조적 제약으로 이류체 포그시스템의 설치보다 광선 선택형 차광제를 도포하는 것이 더 좋은 방법으로 사료된다.

• Journal of Acupuncture Research
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• 제19권2호
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• pp.114-127
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• 2002

Objective : The purpose of this study is to investigate the mechanism and effect of moxibustion objectively and to be used as the quantitative data for developing the new thermal stimulating treatment by observing the combustion time and temperature of commercial moxaes. Methods : We have selected two types(large-size moxa A(LMA), large-size moxa B (LMB)) among large moxaes used widely in the clinic. We examined combustion times, temperatures in each period during a combustion of moxa. Results : 1. The combustion time in the preheating period was about 30sec in both moxaes on the non-contact heated surface. 2. The combustion time in the heating period was about 345sec in LMA and about 1391 sec in LMB, about 4 times longer in LMB on the non-contact surface. 3. The maximum temperature in the heating period was $44.5^{\circ}C$ in LMA and $45.4^{\circ}C$ in LMB respectively, higher by $0.9^{\circ}C$ in LMB. The average temperature in the heating period was $35.5{\sim}37.6^{\circ}C$ in LMA and $36.0{\sim}39.8^{\circ}C$ in LMB, a little higher in LMB. 4. The combustion time in the retaining period in LMA was 45.4sec and 13% of that in the heating period, and in LMB 594.7sec and 43% of that in the heating period on the non-contact surface. 5. On the point(PH) measured maximum temperature, the average temperature during the retaining period was $44.0^{\circ}C$, $42.9^{\circ}C$ respectively and the temperature at an end of the retaining period was $43.0^{\circ}C$, $40.2^{\circ}C$ respectively. 6. The time at a beginning of the cooling period was about 418 sec from ignition in LMA and 2021sec in LMB, and the temperature at that time was $36.9{\sim}39.1^{\circ}C$ on the non-contact surface. Conclusion : It was thought that not only the figure of moxicombustion device, but also the form and size of moxa had influence on the combustion characteristics deciding the performance of stimulus seriously.

• 한국산학기술학회논문지
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• 제20권12호
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• pp.730-736
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• 2019

친환경 에너지원으로 고려되고 있는 천연가스의 수요가 증가하고 있고 이와 동시에 천연가스의 공급을 위한 대규모 파이프라인의 시장 규모 또한 지속적으로 증가하고 있다. 하지만, 이러한 대규모 파이프라인의 부식은 천연가스 운송의 효율성을 저하시킨다. 이에 본 연구는 천연가스 공급용 대규모 파이프라인을 위한 에너지 자립형 고효율 부식방지 기술에 대한 특허의 정량분석을 통해 관련 기술의 특허권 확보을 위한 전략을 수립하는데 목적을 두고 있다. 본 특허 기술동향 조사에서는, 2018년 6월까지 출원, 공개 및 등록된 한국, 미국, 일본 및 유럽 특허를 대상으로 분석하였으며, 전문가토의를 거쳐 기술분류체계 및 분류기준을 마련하였다. 천연가스 대규모 파이프라인의 부식방지를 위한 외부전원으로 연료전지를 이용하기 위해, 1) 파이프라인의 분기 구조와 설비 설계(감압기/압축기/열교환기) 그리고 2) 고압 천연가스의 감압/예열과 가압/냉각 기술을 구비하는 에너지 제어 시스템 및 방법으로 권리화를 시도해 볼 수 있을 것으로 기대된다.

• 한국식품위생안전성학회지
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• 제12권3호
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• pp.240-253
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• 1997

The main problems contributing to food poisoning outbreaks in institutional settings and a home were reviewed and analyzed through the epidemiological investigations of food poisoning. The major documented factors included improper holding temperatures, inadequate cooking, poor personal hygiene, cross-contamination and contaminated equipment, food from unsafe sources, failure to follow food hygiene policies, and lack of education, training, monitoring and superivision. Usually more than one factor contributed to the development of an outbreak. (1) Use of improper holding temperatures was the single most important factor contributing to food poisoning. They included improper cooling, allowing a laps of time (12 hours or more) between preparing food and eating it, improper hot holding, and inadequate or improper thawing. Food thermometers were not used in most of the instances. (2) In inadequate cooking, the core temperature of food during and after cooking had not been measured, and routine monitoring was limited to recording the temperature of plated meals. Compared with conventional methods of cooking, microwave ovens did not protect against food poisoning as effectively. Centralized food preparation potentially increased the risk of food poisoning outbreaks. (3) Poor personal hygiene both at the individual level (improper handwashing and lack of proper hygienic practices) and at the institutional level (poor general sanitization) increased the risk of transmission. Person to person transmission of enteric pathogens through direct contact and via fomites has been noted in several instances. (4) Obtaining food from unsafe sources was a risk factor in outbreaks of food poisoning. Food risks were high when food was grown or harvested from contaminated areas. Possibilities included contamination in the field, in transport, at the retail site, or at the time it was prepared for serving. (5) Cross-contamination and inadequate cleaning/handling of equipment became potential vehicles of food poisoning. Failure to separate cooked food from raw food was also a risk factor. (6) Failure to follow food hygiene policies also provided opportunities for outbreaks of food poisoning. It included improper hygienic practices during food preparation, neglect of personnel policies (involvement of symptomatic workers in food preparation), poor results on routine inspections, and disregarding the results and recommendations of an inspection. (7) Lack of formal and in-service education, training, monitoring, and supervision of food handlers or supervisors were critical and perhaps neglected elements in occurrences of food poisoning.

• Restorative Dentistry and Endodontics
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• 제36권5호
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• pp.377-384
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• 2011

연구목적: 본 연구의 목적은 열연화주입형 gutta percha와 resilon의 온도 변화에 따른 점탄성 변화를 관찰하고 조작성을 비교하기 위함이다. 연구 재료 및 방법: Obtura-II 시스템을 이용하여 세 종류의 gutta percha와 resilon을 $140^{\circ}C$와 $200^{\circ}C$로 가열한 후 사출 온도를 측정하였다. 점도계를 이용하여 온도 변화에 따른 재료들의 점탄성 특성(전단탄성계수, G'; 전단점성계수, G"; 손실 탄젠트, tan${\delta}$; 복소점도, ${\eta}^*$)을 관찰하였다. 점도계와 차동주사열측정기(DSC)로 재료들의 상전이 온도를 측정하였고 가압법으로 $60^{\circ}C$와 $40^{\circ}C$에서 재료들의 점조도를 비교하였다. 결과: 세 종의 gutta perchas는 온도에 따라 서로 다른 점탄성 특성을 나타냈다. $40-50^{\circ}C$에서 연화된 재료의 고체화 상변이가 일어났고, 점도계와 DSC로 측정된 상변이 시작 온도는 유사하였다. 상변이 시작 온도와 가압 시 점조도는 재료들마다 차이를 보였다(p < 0.05). Resilon은 gutta percha와 비슷한 유변학적 특성을 보였다. 결론: 열연화된 근관충전재는 냉각과정 동안 유변학적 특성의 변화를 나타냈고 재료들마다 서로 다른 점탄성 특성은 근관 내주입 시와 충전 시 서로 다른 조작성을 보임을 알 수 있다.