• BMB Reports
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• v.32 no.3
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• pp.288-293
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• 1999

In order to understand the initial interaction of the substrates malonate, ATP, and CoA with malonyl-CoA synthetase, the catalytic product malonyl-CoA was characterized by NMR spectroscopy and molecular modeling. To assign proton and carbon chemical shifts, two-dimensional $^1H-^1H$ DQF-COSY and $^1H-^{13}C$ HMBC experiments were used. The structure of malonyl-CoA in the solution phase was determined based on distance constraints from NOESY and ROESY spectra. The structures were well-converged around the pantetheine region with the pairwise RMSD value of 0.08 nm. The solution structure exhibited a compact folded conformation with intramolecular hydrogen bonds among its carbonyl and hydroxyl groups. These findings will help us to understand the initial interaction of malonate and CoA with malonyl-CoA synthetase.

• Journal of the Korean Magnetic Resonance Society
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• v.11 no.1
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• pp.10-23
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• 2007

A new disintegrin protein named saxatilin was purified from Korean snake venom (Gloydius saxatilis). Saxatilin is a 73 residue small ploypeptide, which has a primary recognition motif in extracellular matrix, Arg-Gly-Asp (RGD) sequence. Data from inhibition activity assay for the ${\alpha}_v{\beta}_3$ integrin showed that saxatilin showed about 5000-fold higher activity than those of RGD peptides, suggesting that RGD sequence may not be sufficient to induce full cellular function of this site. The solution structures calculated from NMR data were well converged for backbone atoms except RGD loop. The structure revealed that most of tight turns are stabilized by medium range NOE contacts and the RGD motif is located far from the rigid core of the C-terminal domain. The three-dimensional fold and biological function of saxatilin are discussed with those of salmosin, which is a disintegrin protein derived from Agkistrodon halys brevicaudus.

• Proceedings of the Korea Information Processing Society Conference
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• 2012.11a
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• pp.1281-1283
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• 2012

향후 도래할 융합시대의 국가적 발전을 위하여 6T 첨단기술 간의 융합기술을 예측하고 지원하기 위한 거버넌스 체계의 구축이 필요하며, 전략 산업 발굴 및 R&D 지원을 위해서 새로이 발생할 융합기술의 분류체계 분석이 필요하다. 본 연구에서는 6T중 문화(Culture)와 기술이 상호적으로 융합하여 만들어지는 CT(Culture Technology)를 기준으로 연구를 진행하며, 구체적으로 CT를 통해 생성되는 융합형 콘텐츠의 분류체계의 핵심요소 도출에 관하여 연구를 진행한다. ICT 관점에서 융합형콘텐츠의 핵심요소로서 시장성, 응용성, 독창성, 핵심성을 도출하였으며, 생태계적 가치사슬 관점에서 창작성, 가공성, 창출성을 핵심요소로 도출하였다. 또한 융합형콘텐츠의 융합 단계를 창의 혁신 단계로 바라보았으며, 이러한 단계에 따라 ICT 및 생태계적 가치사슬 관점에서 가지는 핵심요소가 다름을 볼 수 있었다. 본 논문은 융합형콘텐츠의 발전 단계로 구분하여 다양한 관점에서 융합형콘텐츠의 발전방향을 바라보아야 하는 시사점을 제시하는데 의의를 가진다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.16 no.6
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• pp.1877-1891
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• 2022

As a part of cloud computing technology, algorithms for cloud task scheduling place an important influence on the area of cloud computing in data centers. In our earlier work, we proposed DeepEnergyJS, which was designed based on the original version of the policy gradient and reinforcement learning algorithm. We verified its effectiveness through simulation experiments. In this study, we used the Proximal Policy Optimization (PPO) algorithm to update DeepEnergyJS to DeepEnergyJSV2.0. First, we verify the convergence of the PPO algorithm on the dataset of Alibaba Cluster Data V2018. Then we contrast it with reinforcement learning algorithm in terms of convergence rate, converged value, and stability. The results indicate that PPO performed better in training and test data sets compared with reinforcement learning algorithm, as well as other general heuristic algorithms, such as First Fit, Random, and Tetris. DeepEnergyJSV2.0 achieves better energy efficiency than DeepEnergyJS by about 7.814%.

• The Bulletin of The Korean Astronomical Society
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• v.40 no.1
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• pp.43.3-44
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• 2015

We analyze the clustering of large scale structure in the Universe in a model independent method, accounting for anisotropic effects along and transverse to the line of sight. A large sample of 690,000 galaxies from The Baryon Oscillation Spectroscopy Survey Data Release 11 are used to determine the Hubble expansion H, angular distance D_A, and growth rate GT at an effective redshift of z=0.57. After careful bias and convergence studies of the effects from small scale clustering, we find that cutting transverse separations below 40 Mpc/h delivers robust results while smaller scale data leads to a bias due to unmodelled nonlinear and velocity effects. The converged results are in agreement with concordance LCDM cosmology, general relativity, and minimal neutrino mass, all within the $68{\backslash}%$ confidence level. We also present results separately for the northern and southern hemisphere sky, finding a slight tension in the growth rate -- potentially a signature of anisotropic stress, or just covariance with small scale velocities -- but within $68{\backslash}%$ CL.

• Proceedings of the IEEK Conference
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• 2001.09a
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• pp.535-538
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• 2001

In this paper, we present a novel method to solve the inevitable RGB beam mismatch problem in projection TV receivers. Conventional methods solve the mismatch problem by directly controlling the cathode ray tube (CRT) using the convergence yoke (CY). Unlike conventional methods, the proposed method is based on digital video processing using image warping techniques. Firstly RGB beam projection paths are mathematically modeled. Then based on the modeling, the input video signal to CRT is prewarped so that RGB beams are landed at the same point on the screen. Since the proposed method is based on a digital video processing instead of using CY, it can outperform the conventional method in terms of quality and cost. The experimental results with a real 60´projection TV demonstrate that the proposed method indeed produces converged images on the projection TV screen.

• Preventive Nutrition and Food Science
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• v.21 no.2
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• pp.85-89
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• 2016

Omega-3 rich fish oils are extremely labile, thus requiring control of oxidation and off flavor development. A recently proposed emulsification method, layer-by-layer (LbL) deposition, was found to be a plausible method to enhance the characteristics of bioactive ingredients, especially lipids. The present work was designed to test the possibility of enhancing the uptake and utilization of omega-3 fatty acids present in fish oil. The bioavailability of nano-emulsified fish oil was monitored in terms of intestinal absorption as well as skin permeability by using the everted intestinal sac model and Franz cell model. The skin permeability and intestinal absorption characteristics was significantly improved by LbL emulsification with lecithin/chitosan/low methoxypectin. Multilayer encapsulation along with nano-emulsification can be a useful method to deliver biologically active lipids and related components, such as fish oil. The protective effect of this tool from lipid oxidation still needs to be verified.

• Proceedings of the Korea Information Processing Society Conference
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• 2010.04a
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• pp.143-145
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• 2010

유비쿼터스 컴퓨팅이란 언제 어디서나 사용자가 원하는 서비스를 제공받을 수 있는 컴퓨팅 환경을 말한다. 최근 네트워크와 컴퓨팅 기술이 발달하고 서비스에 대한 수요가 늘어남에 따라 유비쿼터스 컴퓨팅에 대한 관심도 증가하고 있으며 지속적인 연구가 이루어지고 있다. 그 동안 이루어진 많은 연구들을 통해 유비쿼터스 컴퓨팅 환경을 구축하기 위한 기반기술에 큰 발전이 있었다면, 최근에는 실제 유비쿼터스 환경에서 사용자에게 제공되는 서비스 컨텐츠의 효과적인 개발 및 확대에 대한 관심이 높아지고 있다. 모든 개체들이 네트워크로 연결되는 유비쿼터스 컴퓨팅 환경에서는 대부분의 사용자 컨텐츠가 네트워크를 통해 호출할 수 있는 원격 서비스의 형태로 제공된다. 또한 이러한 서비스들은 웹 서비스나 OpenAPI 등 다양한 형태로 존재하므로 이러한 원격 서비스들이 효과적으로 융합되고 재생산 될 수 있어야 한다. 따라서 본 논문에서는 기존에 존재하는 형태의 원격 서비스들을 융합하여 새로운 서비스를 개발하기 위한 기법 및 도구를 제시한다. 이를 위해 본 논문에서는 유비쿼터스 컴퓨팅 환경에서 제공되는 서비스 형태를 U-Service로 정의하며, U-Service를 효과적으로 명세하고 융합할 수 있는 기법 및 도구를 제시한다.

• Journal of the Korea Society of Computer and Information
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• v.19 no.4
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• pp.149-158
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• 2014

The rapidly changing 21st-century knowledge and information society is emphasizing converged education that crosses various academic fields. In particular, the society expected the cultivation of the talent who balance scientific creativity and artistic sensitivity by adding arts to the existing converged education revolving around science and technology. However, at present, most STEAM education has been actively conducted with a focus on science and technology, whereas the subject of arts has been regarded or utilized as a supplementary means. Its problem is that the educational characteristics and values of art education have not been effectively utilized in educational terms and this could lead to superficial integrated education. In this respect, this study had the knowledge of various fields, such as science, technology, and mathematics, utilized usefully during the process of experiencing and creating arts. Accordingly, this study designed an education programs as with the case of Nam-Jun Baek who expanded the dominion of arts by creatively utilizing his own time's scientific technologies. In this educational process, the target program was developed in a manner that enables EPL to be utilized essentially as the study's knowledge-based tool and medium. The results of applying this educational program in 5th-grade elementary school students showed that the program has positive effects on the creative attributes of the students.

• International journal of advanced smart convergence
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• v.9 no.1
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• pp.29-36
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• 2020

We aim to reinterpret Bong Joon-ho's Snowpiercer through theory of posthumanism. Posthuman is a compound word of 'post' and 'human', which means transcendent-man. However, we would like to extend the meaning of posthuman or cyborgs as not only to "new human figure, or transcendent-man" but as to "human living in a digital age of converged technology". Through the extension of the meaning of posthuman, we would be able to not only find posthuman in Science Fiction movies but also apply it to our real world. Also, through the extended meaning, we will reinterpret all the elements from the film as cyberspace and as posthuman or cyborgs. Moreover, through examination of these "cyborg figures" in Bong Joon-ho's Snowpiercer (2013), we argue that the film is criticizing posthumanism in the reality that these days, people are losing the humanity due to the combination with the machine. It seems that he claims of the collapse of the current system, suggesting new human generation as the solution.