• KSBB Journal
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• v.18 no.2
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• pp.155-160
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• 2003

The effect of dissolved oxygen(DO) on microbial transglutaminase(mTG) production by Streptoverticillium morbaraense was studied in on-line computer controlled fermentation system. In order to control dissolved oxygen during fermentation, the agitation speed and aeration rate of 2.5 L fermenter ranged from 260 to 360 rpm and 0.3 to 3.9 L/min, respectively. The maximum microbial transglutaminase production was obtained at controlled 20% of dissolved oxygen among the various dissolved oxygen controlled batch cultures tested. The production of microbial transglutaminase at controlled 20% of dissolved oxygen was about 2.12 U/mL which was 1.1 times higher than that obtained in batch culture without control of dissolved oxygen. Also, the highest microbial transglutaminase production was obtained in fed-batch cultures in which dissolved oxygen was controlled at 20%, and it was improved almost 1.3 times in comparison with that without control of dissolved oxygen. Maximal dry cell weight and microbial transglutaminase production were 13.2 g/L and 2.6 U/mL, respectively. Finally, it was also found that fed-batch fermentation at controlled 20% of dissolved oxygen showed a good performance for the microbial transglutaminase production by on-line computer controlled fermentation system which may be generally applicable to other microbial cultures.

• Korean Journal of Food Science and Technology
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• v.13 no.1
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• pp.25-29
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• 1981

Harvested asparagus, Viking variety, was stored in normal and controlled atmosphere with and without ‘Butts in water’ to extend shelf life of fresh asparagus. Controlled atmosphere storage significantly reduced bacterial soft rot of asparagus. When asparagus was stored in controlled atmosphere in combination with ‘Butts in water’, asparagus spears could be stored over 3 weeks without noticeable soft rot. Texture of stored asparagus, as measured by Instron and fiber analysis, became tougher as the storage time was extended. Increase of fiber content in asparagus was significantly reduced by controlled atmosphere storage and fiber content actually decreased in asparagus stored in controlled atmosphere in combination with ‘Butts in water’. Asparagus stored in controlled atmosphere had markedly less chlorophyll destruction than that in normal atmosphere. Reflectance color values of stored asparagus were closely associated with chlorophyll content in asparagus. Considering all quality factors of stored asparagus, controlled atmosphere in combination with ‘Butts in water’ was the best storage method to maintain overall quality of harvested asparagus over 3 weeks.

• Proceedings of the Korean Vacuum Society Conference
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• 2011.02a
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• pp.2-2
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• 2011

Single-walled carbon nanotubes (SWNTs) have been considered as a promising candidate for nextgeneration electronics due to its extraordinary electrical properties associated with one-dimensional structure. Since diversity in electronic structure depends on geometrical features, the major concern has been focused on obtaining the diameter, chirality, and density controlled SWNTs. Despite huge efforts, the controlled synthesis of SWNTs has not been achieved. There have been various approaches to synthesize controlled SWNTs by preparation of homogeneously sized catalyst because the SWNTs diameter highly depends on catalyst nanoparticles size. In this study, geometrically controlled SWNTs were synthesized using designed catalytic layers: (a) morphologically modified Al2O3 supporting layer (Fe/Al2O3/Si), (b) Mo capping layer (Mo/Fe/Al/Si), and (c) heat-driven diffusion and subsequent evaporation process of Fe catalytic nanoparticles (Al2O3/Fe/Al2O3/Si). These results clearly revealed that (a) the grain diameter and RMS roughness of Al2O3 supporting layer play a key role as a diffusion barrier for obtaining Fe nanoparticles with a uniform and small size, (b) a density and diameter of SWNTs can be simultaneously controlled by adjusting a thickness of Mo capping layer on Fe catalytic layer, and (c) SWNTs diameter was successfully controlled within a few A scale even with its fine distribution. This precise control results in bandgap manipulation of the semiconducting SWNTs, determined by direct comparison of Raman spectra and theory of extended tight binding Kataura plot. We suggest that these results provide a simple and possible way for the direct growth of diameter, density, and bandgap controlled SWNTs by precise controlling the formation of catalytic films, which will be in demand for future electronic applications.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.30 no.2
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• pp.1-18
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• 2017

Objectives : This review aims to evaluate a risk of bias by risk of bias tool and RoBANS(Risk of Bias Assessment tool for Non-randomized Study) tool for clinical trial papers proving treatment effect of Korean medicines to alopecia and provides the newest reason of effectiveness of herbs to alopecia. Methods : Data were collected through electronic database including NDSL, KISS, KMBASE, Koreantk, OASIS, KoreaMed, KISTI, Pubmed, Cochrane CENTRAL and CINAHL. Two experts in Oriental Medicine assessed risk of bias of randomized controlled trials by Cochrane group's Risk of Bias tool and non-randomized controlled trials by RoBANS tool after searching, reviewing and selecting papers. Results : Total number of selected trials is 20 including 4 randomized controlled trial, 13 non-randomized controlled trials and 3 case reports. This study evaluate the risk of bias of 17 papers including 4 randomized controlled trials and 13 non-randomized controlled trials except 3 case reports by risk of bias tool and RoBANS tool. All papers of randomized controlled trials are evaluated unclear for random sequence generation and allocation concealment as there are no word on them. And all papers of non-randomized controlled trials are evaluated unclear for blinding of outcome assessments and relatively low for others. Conclusions : Korean medicine intervention can be an effective for treatment in alopecia. It was evaluated by hair density, thickness and expert panel assessment of photographs and all results are statistically significant. But enhancing levels of evidence, we must try to reduce bias in researches and report a safety, protocol and IRB.

• Journal of Korean Association for Spatial Structures
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• v.18 no.1
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• pp.93-100
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• 2018

The retractable roof structures have actions of various types of loads and external forces depending on the retraction and operation conditions of the roof in terms of efficiency of control and maintenance as the aspect of structural plan. In particular, there is a need for studies on the establishment of retraction controlled wind velocity to maintain the stable control and usability of roof structure against strong winds or sudden gusts during the retraction of the roof. In this paper, it was intended to provide basic materials for the development of guidelines on the operation and maintenance of domestic retractable buildings with large space by analyzing the factors affecting the retraction controlled wind velocity for the overseas stadiums with the large spatial retractable roof structures where the sliding system was applied on the steel retractable systems. As a result, the controlled wind velocity tends to decrease as the retractable roof area increases. On the other hand, the controlled wind velocity tends to increase as the retraction time increases. In addition, in the space-grid roof structures, the spherical roof structures type showed the average controlled wind velocity of 10m/sec lower than that of 17.3m/sec for curved-roof structure type, and in the curved-roof structure type, the truss roof structure showed the average controlled wind velocity of 8.9m/sec which is lower than that of 17.3m/sec for the space for the space-grid roof structure.

• The Korean Journal of Pain
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• v.6 no.1
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• pp.55-59
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• 1993

Using a visual analogue scale, we compare the effect of patient-controlled analgesia and conventional intramuscular opioid regimen in 68 patients undergoing lower abdominal or gynecological surgery. We also recorded the incidence of side effects. We checked visual analogue scale 4 hours interval for 30 cases managed by patient-controlled analgesia and 38 cases of conventional intramuscular opioid group managed by obstetrician. We maintained fentanyl $0.33{\mu}g/kg/hr$ and set self administrable bolus dose $5.0{\mu}g$(lockout interval: 15 min) in patient-controlled analgesia group. Conventional intramuscular bolus injection group were administered meperidine 50 mg for 4 hour interval. Mean visual analogue scale scores obtained by patient-controlled analgesia group and intramuscular bolus injection group were $2.49{\pm}0.67$ and $4.53{\pm}1.28$(p<0.05). Side effects such as; no significant incidence of respiratory depression, urinary retention, postural hypotension, nausea, vomiting and pruritus were developed by either group. These results suggest that patient-controlled analgesia was more effective method compared with conventional intraumuscular opioid injection regimen for post-operative pain management.

• Journal of the Korean Society of Physical Medicine
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• v.4 no.2
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• pp.93-100
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• 2009

Purpose：The purpose of this study was to examine the effects of self-controlled knowledge of result (KR) versus the yoked KR on learning of knee joint proprioception. Methods：Forty volunteer subjects (20 men and 20 women) were randomly assigned to each four groups: 1) self-controlled KR in open kinematic chain, 2) yoked KR in open kinematic chain, 3) self controlled KR in close kinematic chain, and 4) yoked KR in close kinematic chain. The difference between the angle of position and reproduction angle was determined as a proprioception error and measured using an angle reproduction test. The subjects in self-controlled groups were provided with feedback whenever they requested it, whereas the subjects in yoked groups were not provided with feedback. The data were analyzed using a one-way ANOVA. Results：The proprioception errors in close kinematic chain groups decreased significantly compared with those in close kinematic chain groups(p<.05). The proprioception errors in the self-controlled group decreased significantly compared with those in yoked groups during acquisition and retention test(p<.05). Conclusion：Self-controlled knowledge of result during open kinematic chain movement is considered to be a good method on motor learning.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.27 no.4
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• pp.45-57
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• 2014

Objective : This study aims to provide fundamental data for new directions(the improvement directions) from searching research papers of randomized controlled trials among thesis of Atopic Dermatitis related to oriental medicine in Korea from 2004 to 2014 and identifying the problem and level of a clinical study through an assessment of the quality, CONSORT statement. Methods : Data was collected through the Koreanstudies Information Service System(KISS). Two experts in Oriental Medicine reviewed the title and abstract in thesis, the results of searching the title, "Atopic dermatitis" and topic, "oriental medicine" at KISS, and then they handsearched Randomized Controlled Trials related to oriental medicine in Korea. According to guidelines defined by CONSORT statement, they assessed whether 37 items were followed by guidelines at yes or no answers in order to evaluate the quality as well. They assessed the definition of each item independently. After comparing, they made a decision on the item of different outcomes through an agreement with a third party. Results : Total number of randomized controlled trials in Atopic Dermatitis related to oriental medicine is eleven. A randomized controlled trial was first published in 2007. One or two papers associated it were released every year except 2013. 9 papers of them were approved by Institutional Review Board and were received written consent. The study included between 20 to 40 subjects for 2-arm parallel study design. The effect of treatment was observed for 4 to 8 weeks. On average, the number followed guidelines was 18.64 among those of 37 CONSORT statement and 50.38% of them was followed overall. Conclusion : As an interest about randomized controlled trials was increased, it was needed to care the standard providing information of CONSORT statement on randomized controlled trials related to oriental medicine in Korea. It is suggested to provide more clear information about it, so that it can be a motive for improving quality of the journal in oriental medicine.

• The Transactions of the Korean Institute of Electrical Engineers B
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• v.52 no.5
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• pp.238-245
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• 2003

In this paper, a single Phase voltage source voltage-controlled active power filter(APF) for power quality improvement was proposed. The proposed APF has the performance of harmonic suppression and unity power factor correction. The performance of harmonic suppression can be obtained by controlling the waveshape of the APF output voltage to be sine wave. And, unity power factor is controlled by the reactive power control loop of the APF output. Simulation and experimental results using diode rectifier showed that the voltage-controlled APF, unlike the current-controlled APF, can reduce the voltage harmonics as well as current harmonics. Also the results showed that the input dover factor and power quality were greatly improved.

• Transactions of the Korean Society of Automotive Engineers
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• v.6 no.2
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• pp.191-202
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• 1998

An electronic-hydraulic controlled line pressure system was suggested based on the mechanical controlled CVT base model. As a high level control strategy, a 3-D optimal line pressure map was obtained considering the driver's desire, driving conditions. Also, PID type low level controller was designed. Using the high level control strategy and the dynamic models of the base model CVT with electronic controlled line pressure system, performance simulations were carried out. It is seen from the simulation results that fuel economy of the electronic controlled strategy keeps the line pressure low, which results in the improved efficiency of the hydraulic system.