• Title/Summary/Keyword: Control-Interval

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Effect of High-Intensity Interval Training on Acute Liver Failure Induced by D-Galactosamine/Lipopolysaccharide in Balb/c Mice (고강도 인터벌 트레이닝이 D-Gal/LPS로 유도된 마우스의 급성 간 부전에 미치는 효과)

  • Cho, Jin-Kyung;Park, Soo-Hyun;Kang, Hyun-Sik
    • Exercise Science
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    • v.26 no.3
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    • pp.223-228
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    • 2017
  • PURPOSE: This study investigated the protective role of high-intensity interval training against acute liver injury induced by D-galactosamine (D-Gal)/lipopolysaccharide (LPS). METHODS: A total of 30 male BALB/c mice aged 5-week were randomly assigned to high-intensity, interval training group (EX, n=10) or control group in cage (Non-EX, n=20) for 10 weeks. Peritoneal injection of D-Gal (700 mg/kg body weight) and LPS ($10{\mu}g/kg$ body weight) was applied to induce acute liver injury, and liver tissue was harvested 6 hours after the injection. Hematoxylin and Eosin (H&E) staining was used for liver histology. Real-time PCR was used to quantify expression of pro-inflammatory and anti-inflammatory genes in the liver. RESULTS: The liver histology showed that D-Gal/LPS treatment resulted in hepatic damage and increased number of neutrophils in conjunction with upregulation of hepatic IL-6 and $TNF-{\alpha}$ mRNAs and downregulation of hepatic $PPAR{\alpha}$ and SIRT1 mRNAs. On the other hand, the 10-week interval training resulted in a significant improvement in cardiorespiratory fitness assessed as run time to exhaustion on a treadmill. In addition, the interval training attenuated the D-Gal/LPS-induced liver damage and increased number of neutrophil in conjunction with downregulation of hepatic IL-6 and $TNF-{\alpha}$ mRNAs and upregulation of hepatic $PPAR{\alpha}$ and SIRT1 mRNAs. CONCLUSIONS: This study suggests that high-intensity interval training suppresses the D-Gal and LPS-induced acute liver damage and inflammatory responses.

An Economic Design of $\bar{X}$ Control Charts with Variable Sample Size and Sampling Interval (변량표본크기와 변량표본추출구간을 이용한$\bar{X}$관리도의 경제적 설계)

  • 김계완;윤덕균
    • Journal of Korean Society for Quality Management
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    • v.28 no.3
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    • pp.18-30
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    • 2000
  • Recent studies have shown that the $\bar{X}$ chart with variable sampling intervals(VSI) and the $\bar{X}$ chart with variable sample size(VSS) are much quicker than Shewhart $\bar{X}$ chart in detecting shiks in the process. Shewhart $\bar{X}$ chart has been beneficial to detect large shifts but it is hard to apply Shewhart $\bar{X}$ chart in detecting moderate shifts in the process mean. In this article the $\bar{X}$ chart using variable sample size(VSS) and variable sampling Intervals(VSI) has been proposed to supplement the weak point mentioned above. So the purpose of this paper is to consider finding the design parameters which minimize expected loss costs for unit process time and measure the performance of VSSI(variable sample size and sampling interval) $\bar{X}$ chart. It is important that assignable causes be detected to maintain the process controlled. This paper has been studied under the assumption that one cycle is from starting of the process to eliminating the assignable causes in the process. The other purpose of this article is to represent the expected loss costs in one cycle with three process parameters(sample size, sampling interval and control limits) function and find the three parameters.

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A Design of Optimal Interval between Armatures in Long Distance Transportation PMLSM for End Cogging Force Reduction

  • Park, Eui-Jong;Jung, Sang-Yong;Kim, Yong-Jae
    • Journal of Electrical Engineering and Technology
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    • v.11 no.2
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    • pp.361-366
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    • 2016
  • Although the permanent magnet linear synchronous motor is a motor useful for transportation systems thanks to its high speed, high acceleration and deceleration, the linear motor generally has armatures installed on the full length of the transport path. It results in the increase in material costs and manufacturing time. As a means to solve this problem a stationary discontinuous armature system is suggested. However, it involves the following two issues. The first issue is it is impossible to control the mover in the section where any armature is not installed as armatures are distributed. The second one is increasing cogging force due to the ends of the armatures. Therefore, this study aims to solve these problems by adjusting intervals between armatures to control the mover anywhere, and to design the interval between armatures optimally to minimize the end cogging force. The suitable distance was deduced. It addressed the problems and showed suitability for long distance transportation PMLSM.

Nonparametric Method for a Non-inferiority Test using Confidence Interval (신뢰구간을 이용한 비열등성 시험에서 비모수적 검정법)

  • Park, Sujung;Kim, Dongjae
    • The Korean Journal of Applied Statistics
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    • v.27 no.5
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    • pp.833-842
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    • 2014
  • Non-inferiority trials indicate whether the effect of an experimental treatment is not worse than an active control. Chen et al. (2006) and Kang (2010) proposed a test method for non-inferiority trials using confidence intervals. In this paper, we suggest a new nonparametric method using a confidence interval based on Wilcoxon rank-sum test and Hodges-Lehmann estimator of active control. A Monte-Carlo simulation study compares the type I error and the power of the proposed method with previous methods.

Train Regulation by the Advanced Algorithm for Subway (개선된 알고리즘에 의한 지하철 운행간격 제어)

  • Park, Hong-Kyu;Shim, Won-Sup;Hong, Soon-Heum
    • Proceedings of the KIEE Conference
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    • 2002.11d
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    • pp.330-333
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    • 2002
  • Even if the train of subway starts in a certain interval from the origin according to the operation plan. as the number of passenger gets increased during operation. the boarding and getting-off time will increase, and the temporary breakdown happens to the system of train during operation, causing the delay from the operation plan. this leads to the vicious circle of train operation. making the interval of train operation irregular in downtown especially. To solve this problem, we propose the method of advanced algorithm by the actual data relating to the train operation including operation time required between stations, distance between stations. capability of train, and the dwelling time, location and distance between the preceding train and next one. The central train control system adjusts the dwelling time at each station in order to recover the delayed time, and increase the operation speed at the each station. As control algorithm is applied the dwelling time and to increase the speed, the train maintains certain interval after certain amount of time passes.

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Reproductive Functions in Nili-Ravi Buffaloes after Short Term Treatment with Recombinant Bovine Somatotropin Hormone

  • Usmani, R.H.;Athar, I.H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.10 no.2
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    • pp.229-232
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    • 1997
  • Effects of short-term treatment with somidobove (recombinantly produced bovine somatotropin, BST) on estrous cyclicity and fertility were studied in dairy buffaloes. Twenty buffaloes of Nili-Ravi breed calving during the same season were assigned to either control (n=8) or treated group (n=12). The buffaloes of treated group received single infection (prolonged release) of 320 mg of somidobove on day-60 postpartum. The mean values for interval to first postpartum estrus, first service conception rate, services per conception, service period and calving interval for the treated group were 96.4 days, 66.7%, 1.70, 164 days and 473 days, respectively. The corresponding values for the control group were 92.5 days, 62.5%, 1.87, 135 days and 439 days. Means of all variables did not differ between control and treated group (p > 0.05). Three buffaloes of the control and four buffaloes of the treated group did not conceive at first service. Out of these, two buffaloes of control and one buffalo of treated group exhibited normal estrous cycles. It is concluded from these data that short term BST-treatment has no adverse effect on reproductive functions of dairy buffaloes.

A Comparative Study on the Sizing Systems of the Infants and Children's Swim-suit (유유아 수영복의 치수체계 비교 연구)

  • Yi Kyong-Hwa;Jung Hae Sun
    • Journal of the Korean Society of Clothing and Textiles
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    • v.29 no.1 s.139
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    • pp.1-12
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    • 2005
  • This study was to suggest a feasible sizing system of infants and children's swim-suits. The basic body dimensions were selected after surveying the swimsuit manufacturers. The control dimensions and the secondary dimensions were taken from the 1997 National Anthropometric Survey data for the establishment of the sizing system. While in the current market swimsuit sizes were generally measured by the hip circumference for boys, and the bust and hip circumference for girls, the height was selected in this study as the control dimension because the height is well recognized by the customers and the KS standards specify the height to be the control dimension for infant's and children's wear. In the new sizing system of this study, the height was a control dimension, and hip was selected as a secondary dimension for boys. and bust and hip were selected as secondary dimensions for girls. Conclusively, in this study we suggest 12 sizes in case of 5cm height interval by the KS sizing system and 7 sizes in case of loom height interval by the current market sizing system, based on the height as a control dimension, for a standard swim-suit sizing system for infants and children.

A Certain Class of Root Clustering of Control Systems with Structured Uncertainty (구조적불확실성을 갖는 제어시스템의 Root Clustering 해석)

  • 조태신;김영철
    • Journal of the Korean Institute of Telematics and Electronics B
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    • v.32B no.10
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    • pp.1259-1268
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    • 1995
  • This note presents the robust root clustering problem of interval systems whose characteristic equation might be given as either a family of interval polynomials or a family of polytopes. Corresponding to damping ratio and robustness margin approximately, we consider a certain class of D-region such as parabola, left-hyperbola, and ellipse in complex plane. Then a simpler D-stability criteria using rational function mapping is presented and prove. Without .lambda. or .omega. sweeping calculation, the absolute criteria for robust D-stability can be determined.

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