• Title/Summary/Keyword: Control experiment

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Effects of Black Ginseng on Hypertension-induced Rats (흑삼이 폐고혈압 유발 흰쥐에 미치는 영향)

  • Song, Nak-Keun;Choi, Hak-Ju;Kim, Dong-Hee;Roh, Seong-Soo;Seo, Young-Bae
    • The Korea Journal of Herbology
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    • v.24 no.4
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    • pp.69-75
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    • 2009
  • Objectives : To access the safety and efficacy of Black Ginseng (BG), a traditional herbal medicine on hypertension, we examined various parameters involved in the pathogenesis of hypertension. Methods : We made deoxycorticosterone acetate (DOCA;25 mg/kg/3times/weeks for 3 weeks)-induced hypertension Sprague-Dawley (SD) rats. And experiment group was treated with extract of black ginseng (BG;200 mg/kg/day). Results : In results, the weight of experiment group treated with BG was increased compared with normal and control group. And the heart and lung weights of experiment group were decreased compared with control group. The blood pressure and pulse rate of group treated with BG were significantly decreased compared with control group. In addition, BG greatly reduced the levels of aldosterone. These results suggested that BG has suppressive effects on hypertension, and BG has potential as a safe and effective therapeutics for hypertension. Conclusions : The present data show evidences on anti-hypertension activity of BG in an experimental animal system, which can provide further insights into the development of anti-hypertension therapeutic agents.

Effects of Treatment Using PNF Pattern Irradiation in the Weight-Bearing Position on Pain and Foot Alignment in a Patient with Patellofemoral Pain Syndrome: A Single-Subject Experimental Study

  • Dong-Kyu Kim;Duck-Won Oh
    • PNF and Movement
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    • v.22 no.2
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    • pp.171-180
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    • 2024
  • Purpose: This study aimed to investigate the use of insoles in patients with temporomandibular joint disorders to assess the function and changes in pain when walking in daily life. Methods: Sixty-five patients with temporomandibular joint disorder, were selected, with 34 assigned to the control group and 31 to the experimental group. The control group walked more than 7,000 steps per day in their daily life, while the experimental group wore insoles and was instructed to take at least 7,000 steps every day. To evaluate the effect on temporomandibular joint pain, steady-state pain, maximum mouth opening, average pain, and the most severe pain were measured before and after the experiment. In addition, to determine function, mouth opening in a comfortable state, mouth opening pain, and the point of sound and the maximum degree of mouth opening were evaluated before and after the experiment. Results: After the experiment, pain, mouth opening, and sound points showed significant differences compared to the control group. However, there was no significant difference in the maximum mouth opening range. Conclusion: The application of air insoles to patients with temporomandibular joint disorder confirmed the function of the temporomandibular joint and its positive effects on pain.

Wheel-Railway Adhesion Characteristics Experiment Machine on Traction System (견인시스템에 대한 점착특성 시험장치)

  • 이사영;오봉환;이복구;김봉희;전지용;김길동;박현준
    • Proceedings of the KIPE Conference
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    • 1999.07a
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    • pp.130-133
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    • 1999
  • It is one of the most effective methods for improving the performance of electric railway vehicles to make better the wheel-railway adhesion characteristics. The purpose of this paper is to develop the equivalent reduction machine to experiment on the adhesion system. The experiment system makes it possible to change the wheel-rail adhesion force with various adhesion parameters, and therewith to test the adhesion control system with the reduction machine in a laboratory.

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A study and experiment on the stabilization characteristic and the stiffness in Active Magnetic Bearing (자기베어링시스템 강성의 실험적 고찰을 통한 안정화 특성에 관한 연구)

  • 강성구;강종규;홍준희
    • Proceedings of the Korean Society of Machine Tool Engineers Conference
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    • 2004.10a
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    • pp.388-392
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    • 2004
  • Due to the lack of stiffness and difficulties of control, it is hard to achieve well balanced magnetic levitation. In this paper, we analysis the current and position stiffness change according to bias current through experiment. Then, compensation equations were presented. After obtaining PD gain for each bias current and PD gain region through levitation experiment, we consider the characteristics.

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THE CHANGE OF BONE FORMATION ACCORDING TO MAGNETIC INTENSITY OF MAGNET PLACID INTO TITANIUM IMPLANT SPECIMENS (타이타늄 임플랜트 시편 내부에 설치한 자석의 자성강도에 따른 골형성 변화)

  • Hwang Yun-Tae;Lee Sung-Bok;Choi Dae-Gyun;Choi Boo-Byung
    • The Journal of Korean Academy of Prosthodontics
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    • v.43 no.2
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    • pp.232-247
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    • 2005
  • Purpose. The purposes of this investigation were to discover the possibility of clinical application in the areas of dental implants and bone grafts by investigating the bone formation histologically around specimen which was depending on the intensity of magnetic field of neodymium magnet inside of the specimens. Material and method. 1. Measurement of magnetic intensity - placed the magnet inside of the specimen, and measured the intensity of magnetic field around the 1st thread and 3rd thread of specimen 20 times by using a Gaussmeter(Kanetec Co., Japan). 2. Surgical Procedure - Male rabbit was anesthetised by constant amount of Ketamine (0.25ml/kg) and Rompun (0.25ml/kg). After incising the flat part of tibia, and planted the specimens of titanium implant, control group was stitched without magnet, while experimental groups were placed a magnedisc 500(Aichi Steel Co., Japan) or magnedisc 800(Aichi Steel Co., Japan) into it, fixed by pattern resin and stitched. 3. Management after the surgery - In order to prevent it from the infection of bacteria and for antiinflammation, Gentamycin and Ketopro were injected during 1 week from operation day, and dressed with potadine. 4. Preparation of histomorphometric analysis - At 2, 4 and 8 weeks after the surgery, the animals were sacrificed by excessed Ketamine, and then, specimens were obtained including the operated part and some parts of tibia, and fixed it to 10% of PBS buffer solution. After embedding specimens in Technovit 1200 and B.P solution, made a H-E stain. Samples width was 75$\mu$m . In histological findings through the optical microscope and using Kappa image base program(Olympus Co. Japan), the bone contact ratio and bone area ratio of each parts of specimens were measured and analyzed. 5. Statistical analysis - Statistical analysis was accomplished with Mann Whitney U-test. Results and conclusion. 1. In histomorphometric findings, increased new bone formation was shown in both control & experimental groups through the experiment performed for 2, 4 & 8 weeks. After 4 weeks, more osteoblasts and osteoclasts with significant bone remodeling were shown in experimental groups. 2. In histomorphometric analysis, the bone contact ratios were 38.5% for experimental group 1, 29.5% for experimental group 2 and 11.9% for control group. Experimental groups were higher than control group(p<0.05) (Fig. 6, Table IV). The bone area ratios were 60.9% for experimental group 2, 46.4% for experimental group 1 and 36.0% for control group. There was no significantly statistical difference between experimental groups and control group(p<0.05) (Fig. 8, Table VII) 3. In comparision of the bone contact ratios at each measurement sites according to magnetic intensity, experimental group 2(5.6mT) was higher than control group at the 1st thread (p<0.05) and experimental group 1 (1.8mT) was higher than control group at the 3rd thread(p<0.05) (Fig. 7, Table V, VI). 4. In comparision of the bone area ratios at each measurement sites according to magnetic intensity, experimental group 2(5.6mT) was higher than control group and experimental group 1 (4.0mT) at the 1st thread(p<0.1) and experimental group 2(4.4mT) was higher than experimental group 1 (1.8mT) at the 3rd thread(p<0.1) (Fig. 9, Table IX, X). Experiment group 2 was largest, followed by experiment group l and control group at the 3rd thread of implant. There was a significant difference at the 1st thread of control group & experiment group 2, and at 1st thread & 3rd thread of experiment group 1 & 2, and not at control group experiment group 1.(p<0.1)

The Effects of Muscle Relaxation to The Rheumatoid Arthritis Patients' Adaptation (류마티스성 관절염 환자의 적응에 미치는 근이완술에 효과)

  • Jung, Hyan-Mi
    • Journal of muscle and joint health
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    • v.1 no.1
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    • pp.31-47
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    • 1994
  • The purposes of this research are to examine the effects of muscle relaxation to the rheumatoid arthritis patients' physiological, psychological, and social adaptation, and to verify that the technique Is an effective tool for improving the patients' adaptation. This research utilized a qusi-experimental design that compares the pre-experiment measures and the post-experiment measures. The subjects of this study were 37 out-patients who were diagnosed for rheumatoid arthritis in P university hospital and K clinic between September 12, 1993 and November 30, 1993. The experimental group consisted of patients treated on Monday, Wednesday and Friday. The control group consisted of patients treated on Tuesday, Thursday and Saturday The pre-experimental survey utilized the following tools. The physiological adaptation was measured by a graphic rating scale for pain and activity of daily living. The psychological adaptation was measured by Zung's depression scale and Rosenberg's self-esteem scale : and the social adaptation was measured by Derogatis' psychosocial adjustment scale. The experimental group received muscle relaxation treatment for 15 minutes per day for the period of 2 weeks, the control group received no treatment and had quiet time. The post-experiment measurement was carried out similar to the pre-experiment survey, SPSS $PC^+$ is used to analyze the collected data. The reliabilities of the measurement tools were examined by Cronbach's ${\alpha}$ coefficients. The homogeneities between the experimental and control groups were tested by t-test and chi-square test, hypotheses were tested by t-test. This research found that the general characteristics between the groups were statistically homogenious. The physiological, psychological, and social adaptation between the groups in the pre-experimental survey were also statistically homogenious. The results of this research can be summarized as follows : 1. Concerning the Physiological adaptation, the experimental group showed a statistically lower pain score than the control group. Thus, muscle relaxation was effective to relieve the pain of rheumatoid arthritis patients (t=-2.95, p=.006). 2. Concerning the psychological adaptation, the experimental group showed a statistically lower depression score than the control group. Thus, muscle relaxation was effective to reduce the patient's depression(t=-4.00, p=.001). 3. Concerning social adaptation, the experimental group showed a statistically higher score for the health maintenance and disease control than the control groups. Thus, muscle relaxation was effective for the health maintenance and disease control (t=2.09, p=.004). This research showed that the muscle relaxation is a nursing intervention that can promote the physiological, psychological and social adaptation of the rheumatoid arthritis patients in terms of short-term and cognitive changes. However, more fundomental changes in behavior and long-term physiology could not be found through such a short-term relaxation treatment.

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Beneficial Effects of Dietary Antiacarcinogenic Conjugated Linoleic Acid(CLA) on the Performances of Laying Hens and Broilers

  • Byon, Jai-II;Park, Sook-Jahr;Park, Kyung-Ahr;Ha, Jeung-Key;Kim, Jeong-Ok;Ha, Yeong-Lae
    • Preventive Nutrition and Food Science
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    • v.1 no.1
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    • pp.99-105
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    • 1996
  • Effects of conjugated linoleic acid(CLA), known as an effective anticarcinogen in several aminal models, on the egg production and egg weight of laying hens, and the weight gains of broilers were investigated. CLA was synthesized from corn oil by the alkaline isomerization method and purified by the low-temperature precipitation method. Diets for laying hens and for broilers were synthesized to meet the specification of their NRC standard rationals. Two separated experiments(Experiment I and II) were conducted for laying hens. in experiment I, 45 hens(300 days of age) were divided into 15 hens per treatment group; each hen was housed in wired cage located in a temperature and humidity-controlled house and adopted to the control diet. One week later, each group was subjected to one the four treatment groups for 5 weeks : control, 1.0% CLA, 2.5% CLA and 5.0% CLA diets. Diet and water were ad libitum. The condition of experiment II was the same as that of experiment I except for the addition of 5% corn oil diet and the extension of feeding period to 7 weeks. Egg production, egg weight and feed intake were recorded every week. Forty-five broilers(10day of age) were adopted to the control diet for a week and then switched to the treatment diets for 5 weeks : control, 1.0% CLA, 2.5% CLA, 5% CLA and 5% corn oil, Body weight and feed intake of broilers were measured every week. Diets supplemented with various amounts of CLA enhanced the egg production and increased the egg weight regardless laying hen's age(150 days or 300 days) as compared to control diet. The most effective diet for the egg production and egg weight of young hens(150 days of age) was found to be 1.0% CLA diet, but relatively higher CLA diet(2.5% CLA) was required for old hens (300 day of age) to obtain similar results as seen in younger hens. All hens treated with CLA ate greater amount of feed than control hens. Broilers treated with various amount of CLA ate less feed as compared to control ones, but the body weight gain was greater than the control broilers. These results indicate that CLA enhanced the egg production and agg weight of laying hens, and increased the body weight gain of broilers with less diet consumption.

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Proper Application Concentration of Oleic Acid for Eco-friendly Control of Whiteflies by Two-fluid Fogging System in Greenhouses (이류체 포그 시스템을 이용한 친환경적 가루이 방제시 올레산의 적정 농도)

  • Kim, Sung Eun;Lee, Sang Don;Lee, Moon Haeng;Sim, Sang Youn;Kim, Young Shik
    • Journal of Bio-Environment Control
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    • v.21 no.3
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    • pp.299-304
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    • 2012
  • In this work, we experimented with the two-fluid fogging system that eco-friendly prevents whiteflies in greenhouses in order to find the optimal concentration of oleic acid supplied through the system and to evaluate the control value of three consecutive treatments. The first experiment, which was to find the optimal concentration of oleic acid, used "Dotaerang Gold" tomatoes grown in stand-alone plastic greenhouse at Buyeo Tomato Experiment Station. We tested three levels of concentration of oleic acid, which were 0, 2000, and 4000 ppm. The second experiment, which was to evaluate the control value of three consecutive treatments of oleic acid, used "Rokusanmaru" tomatoes grown in Venlo type glasshouse at Gyeonggi-Do Agricultural Research & Extension Services. In this experiment, oleic acid of 2000 ppm was applied three times with two days intervals. The number of whiteflies was counted 2 two days after the last application of oleic acid. Even when oleic acid was not being applied, the two-fluid fogging system was run from 9:00 am to 5:00 pm whenever the temperature is higher than $25^{\circ}C$ or the humidity is lower than 75%. In the first experiment, the control value was 81.6% with 2000 ppm of oleic acid and 93.6% with 4000 ppm. It means that the higher the concentration is, the greater the control value. In the second experiment, 2000 ppm treatment resulted in 85.8% of the control value, which is higher than the required standard for insecticides. Hence, spraying oleic acid with the concentration of 2000 ppm three times with two days intervals turned out to be a very effective in the eco-friendly prevention of whitefly.

A Study on the Control Method for the Tool Path of Aspherical Surface Grinding and Polishing (비구면 연삭 및 연마를 위한 공구 경로 제어에 관한 연구)

  • Kim, Hyung-Tae;Yang, Hae-Jeong;Kim, Sung-Chul
    • Journal of the Korean Society for Precision Engineering
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    • v.23 no.1 s.178
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    • pp.113-120
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    • 2006
  • This paper proposed the control algorithm fur aspheric surface grinding and was verified by the experiment. The functions of the algorithm were simultaneous control of the position and interpolation of the aspheric curve. The non-linear formula of the tool position was derived from the aspheric equations and the shape of the tool. The function was partitioned by an certain interval and the control parameters were calculated at each control section. The movement in a session was interpolated with acceleration and velocity. The position error was feed-backed by rotary encorder. The concept of feedback algorithm was correcting position error by increasing or decreasing the speed. In the experiment, two-axis machine was controlled to track the aspheric surface by the proposed algorithm. The effect of the control and process parameters was monitored. The result showed that the maximum tracking error was under sub-micro level for the concave and convex surfaces.