• Journal of the Korean Applied Science and Technology
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• v.35 no.2
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• pp.519-531
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• 2018

The purpose of this study was to investigate the effects of combined exercise program on short physical performance battery, bone mineral density and parathyroid hormone levels in elderly women. This study subjects were 22 elderly female volunteers, aged 65-75 years and they divided into the combined exercise group(n=11) and the "no exercise" control group(n=11). The combined exercise included the line dance program performed twice per week for 60 minutes and the resistance exercise program performed once per week during 12 weeks. Exercise intensity was progressively increased from RPE "fairly light" to "slightly hard" (from 11 to 14). The findings of this study were as follows; Short physical performance battery(Balance test, gait speed, and rising from a chair five times) and bone mineral density (lumbar spine L2~L4 bone densities, and the T-score) were significantly increased after 12 weeks in the exercise group compared to the baseline. The PTH level was significantly decreased in the exercise group compared to the baseline. In conclusion, regular and continuous physical activity was effective for improving short physical performance and had a positive effect on bone mineral density and parathyroid hormone. With aging, women have decreased muscle strength and bone density and therefore, it is strongly recommended that women need to carry out continuous physical activity to prevent disease and ensure a healthy retirement.

• Journal of Korean Society of Forest Science
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• v.97 no.1
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• pp.61-70
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• 2008

This study was conducted to develop a mobile tower-yarder with tractor for agriculture and forestry that is the efficient yarder in steep terrains, thinning operation and small scale logging operation. It was designed and manufactured that the power source of tower-yarder is equiped three hydraulic pump connected to PTO of tractor, and three hydraulic pump is used to operate the four motor for drum, the cylinder for clutch of interlocker, the cylinder for tower expanding and the out-rigger cylinder. It was to adopt the running skyline system and the inter-lock function, and to equip the double capstan drum, the storage drum and the clutch for interlock in the development of tower-yarder. It was to develop the tower-yarder which the winch torque of double-capstan drum, the traction force of double-capstan drum, the number of rotation of double-capstan drum and the line speed is $191kg{\cdot}m$, 1,910 kgf, 220.5 rpm and 138.5 m/min, respectively. And it was known that the optimum flange diameter of the main and haulback storage drum is about 360 mm and about 460 mm in order to storage the main line length of 250m and the haulback line length of 450 m. The carriage was made to adopt the running skyline system and to equip the lock function in order to the convenience of chocking and the fall down preventing of tree. It was provided to develop the wire remote controller for the inter-lock function, the convenience of control and the efficiency of yarding. In development process, this tower-yarder was attached the 3-point linkage hitch equipment and the tire wheel for the traction and moving of tower-yarder. Also, it was equipped that the out-rigger and the guy line in order to raise the safety and efficiency of yarding of tower-yarder.

• Restorative Dentistry and Endodontics
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• v.14 no.1
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• pp.41-56
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• 1989

The purpose of this study was to examine the effect of temperature dependence of the behavior on the physical properties of posterior composite resins. Three light cure posterior composite resins (Heliomolar, Litefil-P, and P-50) and one chemical cure posterior composite resin (Bisfil-II) were used as experimental materials. Composite resin was placed in a cylindrical brass mold (2.5 mm high and 6.5 mm inside diameter) that was rested on a glass plate. Another flat glass was placed on top of the mold, and the plate was tightly clamped together. After the mold had been filled with the light cure composite material, the top surface was cured for 30 seconds with a light source. Chemical cure resin specimens were made in the same manner as above. Three hundreds and twenty composite resin specimens were constructed from the four composite materials. One hundred and sixty specimens of them were placed in a heater at $50^{\circ}C$, $75^{\circ}C$, $100^{\circ}C$, $125^{\circ}C$, $150^{\circ}C$, $175^{\circ}C$ and $200^{\circ}C$ for 5 minutes or 10 minutes respectively before compressive strengths were measured. Another one hundred and sixty specimens were tested for the diametral tensile strengths in the same way as above. They were randomly divided into eight groups according to the mode of heating methods as follows and stored in distilled water at $37^{\circ}C$ for 24 hours. Group $37^{\circ}C$ - specimens were stored at $37^{\circ}C$ in distilled water for 24 hours. Group $50^{\circ}C$ - specimens were heated at $50^{\circ}C$ after curing. Group $75^{\circ}C$ - specimens were heated at $75^{\circ}C$ after curing. Group $100^{\circ}C$ - specimens were heated at $100^{\circ}C$ after curing. Group $125^{\circ}C$ - specimens were heated at $125^{\circ}C$ after curing. Group $150^{\circ}C$ - specimens were heated at $150^{\circ}C$ after curing. Group $175^{\circ}C$ - specimens were heated at $175^{\circ}C$ after curing. Group $200^{\circ}C$ - specimens were heated at $200^{\circ}C$ after curing. Twenty specimens of each of four composite resins were respectively made by insertion of materials into same mold for examining the dimensional changes between before and after heating. The final eighty specimens were stored in distilled water at $37^{\circ}C$ for 24 hours before testing the dimensional changes. Compressive and diametral tensile strengths were measured crosshead speed 1mm/minute and 500Kg in full scale with a mechanical testing machine (DLC 500 Type, Shimadzu Co., Japan). Dimensional changes were determined by measuring the diametral changes of eighty specimens with micrometer (Mitutoyo Co., Japan). Results were as follows: 1. Diametral tensile strengths of specimens in all groups were increased with time heated compared with control group except for that in group $50^{\circ}C$ and the maximum diametral tensile strength was appeared in the specimen of Litefil-P heated for 10 minutes at $100^{\circ}C$. In heliomolar and P-50, it could be seen in the specimen heated for 10 minutes at $150^{\circ}C$, but in Bisfil-II, it could be found in the specimen heated for 5 minutes at $150^{\circ}C$. 2. Compressive strengths of specimens in all groups was tended to be also increased with time heated but that in group $50^{\circ}C$ and the maximum compressive strengths were showed in the same specimens conditioned as the diametral tensile strengths of four composite materials tested. 3. In Heliomolar, Litefil-P, and Bisfil-II, it was decreased in diameters of resin specimens between before heating and increased in diameters of resin specimens after storing in distilled water, but it was not in P-50. 4. There is little difference in diametral tensile strengths, compressive strengths, and dimensional changes followed by heating the resin specimens for 5 minutes and 10 minutes, but there is no statistical significances.

• Herbal Formula Science
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• v.13 no.2
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• pp.1-16
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• 2005

Objectives: To find out the effects GGTl, an antiobestic drug widely used in clinics, has on the blood-antiobestic index and the toxicity index using the data from the hGHTg obese male rats. We looked closely into both of the two indices because GGTl antiobestic effect can happen not only by pharmacological action, but also by its toxicity. Also, we verified the difference in effect between GGTl and reductil (sibutramine), which has been approved by the FDA of the United States. Methods: After performing the experiments for 8 weeks on the hGHTg obese male rats divided into three groups: the control group, the GGTl group, and the reductil (RD) group, we anesthetized the rats with Diethyl ether and took a 3ml blood sample from the heart. Then, after coagulating the blood in room temperature by using the plasma separator, we centrifuged it for 25 minutes in 3,000rpm using the high-speed refrigerated centrifuge. We kept the separated plasma in a deep freezer at $-80^{\circ}C$, and repeatedly measured the antiobestic index and the toxicity index twice using the hematology biochemistry analyzer. Also, in order to judge the indirect toxicity index, we separated liver from kidney and observed them. Results: When we looked at the results of the analysis of covariance on the measuring elements related to the antiobestic index (TC, HDL, LDL, TG, and GLU), there was no significant difference among the groups in all measuring elements. Also, the results of the analysis of covariance on the two roups (RD group and GGTl group) showed that the p-values had no significant difference under the level of significance 0.05. When we looked at the result of the analysis of covariance on the measuring elements related to the toxicity index (GOT, GPT, GGT, CREA, UA, ALB, and TP), we could see that the p-values in GPT, ALB, and TP have a significant difference among the groups. Also, the results of the analysis of covariance about the measuring elements related to the toxicity index on both groups, RD group and GGTl group, showed no significant difference in the p-values of all of the measuring elements in the two groups, RD and GGTl group. Conclusions: In conclusion, through this experiment, the safety of GGTl has been approved, and although the verification on its medical effect has not been clearly approved, when we consider the fact that it belongs to the same group as reductil, an antiobestic drug approved by the FDA of the United States, we could indirectly verify that GGTl has an antiobestic effect. We believe that when doing a sample design for a future experiment, it needs to be performed on a greater sample size based on the power analysis that needs to be performed primarily in experiments, and a more accurate verification is needed through more systematic experiment plans.

• Journal of Korean Medicine Rehabilitation
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• v.19 no.2
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• pp.73-88
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• 2009

Objectives : Neuronal changes that result from treadmill exercise for patients with Parkinson's disease(PD) have not been well documented, although some clinical and laboratory reports suggest that regular exercise may produce a neuroprotective effect and restore dopaminergic and motor functions. However, it is not clear if the improvements are due to neuronal alterations within the affected nigrostriatal region or result from a more general effect of exercise on affect areas and motivation. In this study, we demonstrate that motorized treadmill exercise improves the neuronal outcomes in rodent models of PD. Methods : We used a chronic mouse model of parkinsonism, which was induced by injecting male C57BL/6 mice with 10 doses(Every 12 hour) of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (30 mg/kg) and probenecid (20 mg/kg) over 5 days. These mice were able to sustain an exercise training program on a motorized rodent treadmill at a speed of 18 m/min, $0^{\circ}$ of inclination, 40 min/day, 5 days/week for 4 weeks. At the end of exercise training, we extracted the brain and compared their neuronal and neurochemical changes with the control(saline and sedentary) mice groups. Synphilin protein is the substance that manifestly reacts with ${\alpha}$-synuclein. In this study, we used Synphilin as a manifest sign of recovery from neurodegeneration. We analyze the brain stems of the substantia nigra and striatum region using the western blotting technique. Results : There were no expression of synphilin in the saline-induced groups. The addition of MPTP(1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) greatly accelerated synphilin expression which meant an aggregation of ${\alpha}$-synuclein. But, the MPTP-induced treadmill exercise group showed significantly lower expression than the MPTP-induced sedentary group. This means treadmill exercise has a definite effect on the decrease of ${\alpha}$-synuclein aggregation. Conclusions : In this study, our results suggest that treadmill exercise promoted the removal of the aggregation of ${\alpha}$-synuclein, resulting in protection against disease development and blocks the apoptotic process in the chronic parkinsonian mice brain with severe neurodegeneration.

• The Korean Journal of Air & Space Law and Policy
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• v.30 no.2
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• pp.177-199
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• 2015

Commerce enriches human life enriched and within commerce, transportation of cargo is arguably the most important in business transactions. Traditionally, marine transport has been major commercial transaction, but carriage cargo by air is on the increase. While the fare for freight in comparison with that of ocean is higher, air freight has many benefits that justify the higher shipping fee; lower insurance premium, packing charges, inventory control, cost management and especially speed. Therefore, air freight transport is accumulating gradually. An air waybill(AWB) is needed in the air transport flow. It is a nonnegotiable security, so the holder cannot transfer of a right to a third party. Some scholars suggest that a negotiable AWB is needed. However, it seems nearly impossible to do so; an e-AWB use shows a gain in numbers, even if it has not met expectations. Going forward, it would appear reasonable to conduct a follow-up study on the utility and legal problem for e-AWB. After sending goods, the consignor has the right of disposition of cargo in some cases, and more research is necessary, because it is related to change of ownership and a trade settlement. According to WATS (World Airlines Transport Statistics), the Korean Air took third place in international freight in 2014, and fifth in total, domestic and international to great acclaim. However, there is a lack of research supporting the business showing. It is hope that more studies on e-AWB, stoppage in transit, and a risk of outstanding amount, etc. connect to develop Korean air freight industry.

• Korean Journal of Weed Science
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• v.11 no.2
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• pp.111-116
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• 1991

This studies were conducted to get the basic information on the growth habits of Scirpus planiculmis F. Schmidt for control in poldered paddy field. The distribution of corm was about 16% in 0-5cm, 66% in 5-8 cm. 18% in 8-10cm depth of underground. The mean depth of total corm distribution was about 6.51cm. Number of rhizomes and dormant buds per corm were one to four, respectively. Number of rhizomes. dormant buds and total buds(rhizome+dormant bud) were 2.34, 2.85 and 5.20, respectively. The phyllotaxy of S. planiculmis was 1/3 and bracteal leaf were showed from first to 4th leaves. The period of propagation to 100 plants from emergence was 58.52 and 48 days for corm seeded on March 25th, b4ay 7th and June 6th respectively. Days to emergence of S. planiculmis from emergence of previous plant was gradually shorted. as order of propagation from corm seeded progressed. The other side, length of rhizome, plant height and diameter of culm was increased. The plant height of S. planiculmis was higher than rice plant from early stage in rice direct seeding culture, and from 30 dats after transplanting in rice transplanting culture. Speed of propagation was faster in rice direct seeding culture than in rice trasplanting culture.

• Korean Journal of Agricultural and Forest Meteorology
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• v.11 no.4
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• pp.192-205
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• 2009

The unexpected wind over the Mt. Hwawang on 9 February 2009 was deadly when many spectators were watching a traditional event to burn dried grasses and the fire went out of control due to the wind. We analyzed the fatal wind based on wind flow simulations over a digitized complex terrain of the mountain with a localized heating area using a three dimensional computational fluid dynamics model, CFD_NIMR_SNU (Computational Fluid Dynamics_National Institute of Meteorological Research_Seoul National University). Three levels of fire intensity were simulated: no fire, $300^{\circ}C$ and $600^{\circ}C$ of surface temperature at the site on fire. The surface heat accelerated vertical wind speed by as much as $0.7\;m\;s^{-1}$ (for $300^{\circ}C$) and $1.1\;m\;s^{-1}$ (for $600^{\circ}C$) at the center of the fire. Turbulent kinetic energy was increased by the heat itself and by the increased mechanical force, which in turn was generated by the thermal convection. The heating together with the complex terrain and strong boundary wind induced the unexpected high wind conditions with turbulence at the mountain. The CFD_NIMR_SNU model provided valuable analysis data to understand the consequences of the fatal mountain fire. It is suggested that the place of fire was calm at the time of the fire setting due to the elevated terrain of the windward side. The suppression of wind was easily reversed when there was fire, which caused updraft of hot air by the fire and the strong boundary wind. The strong boundary wind in conjunction with the fire event caused the strong turbulence, resulting in many fire casualties. The model can be utilized in turbulence forecasting over a small area due to surface fire in conjunction with a mesoscale weather model to help fire prevention at the field.

• Proceedings of the Korean Vacuum Society Conference
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• 2013.08a
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• pp.88-89
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• 2013

A variety of influenza A viruses from animal hosts are continuously prevalent throughout the world which cause human epidemics resulting millions of human infections and enormous industrial and economic damages. Thus, early diagnosis of such pathogen is of paramount importance for biomedical examination and public healthcare screening. To approach this issue, here we propose a fully integrated Rotary genetic analysis system, called Rotary Genetic Analyzer, for on-site detection of influenza A viruses with high speed. The Rotary Genetic Analyzer is made up of four parts including a disposable microchip, a servo motor for precise and high rate spinning of the chip, thermal blocks for temperature control, and a miniaturized optical fluorescence detector as shown Fig. 1. A thermal block made from duralumin is integrated with a film heater at the bottom and a resistance temperature detector (RTD) in the middle. For the efficient performance of RT-PCR, three thermal blocks are placed on the Rotary stage and the temperature of each block is corresponded to the thermal cycling, namely $95^{\circ}C$ (denature), $58^{\circ}C$ (annealing), and $72^{\circ}C$ (extension). Rotary RT-PCR was performed to amplify the target gene which was monitored by an optical fluorescent detector above the extension block. A disposable microdevice (10 cm diameter) consists of a solid-phase extraction based sample pretreatment unit, bead chamber, and 4 ${\mu}L$ of the PCR chamber as shown Fig. 2. The microchip is fabricated using a patterned polycarbonate (PC) sheet with 1 mm thickness and a PC film with 130 ${\mu}m$ thickness, which layers are thermally bonded at $138^{\circ}C$ using acetone vapour. Silicatreated microglass beads with 150~212 ${\mu}L$ diameter are introduced into the sample pretreatment chambers and held in place by weir structure for construction of solid-phase extraction system. Fig. 3 shows strobed images of sequential loading of three samples. Three samples were loaded into the reservoir simultaneously (Fig. 3A), then the influenza A H3N2 viral RNA sample was loaded at 5000 RPM for 10 sec (Fig. 3B). Washing buffer was followed at 5000 RPM for 5 min (Fig. 3C), and angular frequency was decreased to 100 RPM for siphon priming of PCR cocktail to the channel as shown in Figure 3D. Finally the PCR cocktail was loaded to the bead chamber at 2000 RPM for 10 sec, and then RPM was increased up to 5000 RPM for 1 min to obtain the as much as PCR cocktail containing the RNA template (Fig. 3E). In this system, the wastes from RNA samples and washing buffer were transported to the waste chamber, which is fully filled to the chamber with precise optimization. Then, the PCR cocktail was able to transport to the PCR chamber. Fig. 3F shows the final image of the sample pretreatment. PCR cocktail containing RNA template is successfully isolated from waste. To detect the influenza A H3N2 virus, the purified RNA with PCR cocktail in the PCR chamber was amplified by using performed the RNA capture on the proposed microdevice. The fluorescence images were described in Figure 4A at the 0, 40 cycles. The fluorescence signal (40 cycle) was drastically increased confirming the influenza A H3N2 virus. The real-time profiles were successfully obtained using the optical fluorescence detector as shown in Figure 4B. The Rotary PCR and off-chip PCR were compared with same amount of influenza A H3N2 virus. The Ct value of Rotary PCR was smaller than the off-chip PCR without contamination. The whole process of the sample pretreatment and RT-PCR could be accomplished in 30 min on the fully integrated Rotary Genetic Analyzer system. We have demonstrated a fully integrated and portable Rotary Genetic Analyzer for detection of the gene expression of influenza A virus, which has 'Sample-in-answer-out' capability including sample pretreatment, rotary amplification, and optical detection. Target gene amplification was real-time monitored using the integrated Rotary Genetic Analyzer system.

• Journal of The Korean Ophthalmological Society
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• v.59 no.11
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• pp.1017-1023
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• 2018

Purpose: A recently introduced phacoemulsification system, the WhiteStar $Signature^{(R)}$ PRO, has demonstrated improved nucleus followability and cutting efficiency via an improved pump regulator with a higher reaction response and an automatic occlusion sensing system. In this study, we compared various phacoemulsification parameters between the new system and an older version of the device. Methods: A total of 80 eyes of 68 patients with cataracts who had undergone phacoemulsification by a single surgeon were included in this study. Forty eyes of patients underwent phacoemulsification using the older $Signature^{(R)}$ system (WhiteStar); these patients were classified as the control group. Another 40 eyes of patients underwent phacoemulsification with the newer enhanced system, the WhiteStar $Signature^{(R)}$ PRO; these patients were assigned to the experimental group. During the operation, operative parameters, including the effective phaco time (parameter of effective phaco time with a specific coefficient for the transversal movement expressed in seconds, EFX), ultrasound time (seconds [s]), effective phacoemulsification time (EPT, s), average phacoemulsification power (AVG, %), and balanced salt solution usage, were measured to determine the performance enhancement offered by the updated system. Central corneal thickness was measured before and after surgery to compare corneal edema. The relationships between the two groups were analyzed using an independent t-test. Results: The Signature $PRO^{(R)}$ system showed a lower EFX (p < 0.001), a shorter EPT (p < 0.001), and a smaller AVG (p < 0.001). Postoperative corneal thickness did not differ significantly between the two groups. Conclusions: Comparing the efficacy of the improved reaction speed of the device and automatic occlusion sensing system in performing phacoemulsification, the updated Signature $PRO^{(R)}$ system demonstrated superior followability and cutting efficiency regardless of nuclear cataract hardness.