• Korean Journal of Veterinary Service
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• v.42 no.2
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• pp.73-83
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• 2019

Foot-and-Mouth Disease (FMD) is a highly contagious trans-boundary viral disease caused by FMD virus, which causes huge economic losses. FMDV infects cloven hoofed (two-toed) mammals such as cattle, sheep, goats, pigs and various wildlife species. To control the FMDV, it is necessary to understand the life cycle and the pathogenesis of FMDV in host. Especially, the protein-protein interaction between FMDV and host will help to understand the survival cycle of viruses in host cell and establish new therapeutic strategies. However, the computational approach for protein-protein interaction between FMDV and pig hosts have not been applied to studies of the onset mechanism of FMDV. In the present work, we have performed the prediction of the pig's proteins which interact with FMDV based on RNA-Seq data, protein sequence, and structure information. After identifying the virus-host interaction, we looked for meaningful pathways and anticipated changes in the host caused by infection with FMDV. A total of 78 proteins of pig were predicted as interacting with FMDV. The 156 interactions include 94 interactions predicted by sequence-based method and the 62 interactions predicted by structure-based method using domain information. The protein interaction network contained integrin as well as STYK1, VTCN1, IDO1, CDH3, SLA-DQB1, FER, and FGFR2 which were related to the up-regulation of inflammation and the down-regulation of cell adhesion and host defense systems such as macrophage and leukocytes. These results provide clues to the knowledge and mechanism of how FMDV affects the host cell.

• Safety and Health at Work
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• v.10 no.1
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• pp.3-20
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• 2019

This review aimed to identify risk factors for occupational accidents and illnesses among young workers in the Nordic countries and to attain knowledge on specific vulnerable groups within the young working force that may need special attention. We conducted a systematic review from 1994 to 2014 using five online databases. Of the 12,528 retrieved articles, 54 met the review criteria and were quality assessed, in which data were extracted focusing on identifying occupational safety, health risk factors, and vulnerable groups among the young workers. The review shows that mechanical factors such as heavy lifting, psychosocial factors such as low control over work pace, and organizational factors such as safety climate are all associated with increased injury risk for young Nordic workers. Results show that exposures to chemical substances were associated with skin reactions, e.g., hand eczema. Heavy lifting and awkward postures were risk factors for low back pain, and high job demands were risk factors for mental health outcomes. The review identified young unskilled workers including school drop-out workers as particularly vulnerable groups when it comes to occupational accidents. In addition, apprentices and young skilled workers were found to be vulnerable to work-related illnesses. It is essential to avoid stereotyping young Nordic workers into one group using only age as a factor, as young workers are a heterogeneous group and their vulnerabilities to occupational safety and health risks are contextual. Politicians, researchers, and practitioners should account for this complexity in the education, training and organization of work, and workplace health and safety culture.

• Journal of Internet Computing and Services
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• v.19 no.6
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• pp.83-89
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• 2018

In workflow process intelligence and systems, workflow process mining and analysis issues are becoming increasingly important. In order to improve the quality of workflow process intelligence, it is essential for an efficient and effective data center storing workflow enactment event logs to be provisioned in carrying out the workflow process mining and analytics. In this paper, we propose a three-dimensional process-aware datacube for organizing workflow enterprise data centers to efficiently as well as effectively store the workflow process enactment event logs in the XES format. As a validation step, we carry out an experimental process mining to show how much perfectly the process-aware datacubes are suitable for discovering workflow process patterns and its analytical knowledge, like enacted proportions and enacted work transferences, from the workflow process enactment event histories. Finally, we confirmed that it is feasible to discover the fundamental control-flow patterns of workflow processes through the implemented workflow process mining system based on the process-aware data cube.

• Journal of Korean Medicine Rehabilitation
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• v.31 no.2
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• pp.25-40
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• 2021

Objectives This study was conducted to analyze the effect of using acupotomy for piriformis muscle syndrome. Methods The databases used for the search were PubMed, Embase, Cochrane library, China National Knowledge Infrastructure (CNKI), Koreanstudies Information Service System (KISS), Research Information Sharing Service (RISS), Oriental Medicine Advanced Searching Integrated System (OASIS), KMbase, and National Digital Science Library (NDSL). The literature was searched using a total of 9 domestic and foreign databases. randomized controlled trial using only acupotomy as an intervention was selected. The selected studies are analyzed the risk of bias through Cochrane risk of bias, and meta-analysis was performed using Revman. Results As a result of meta-analysis of 11 selected studies, acupotomy was more effective than nerve block and acupuncture. In terms of visual analog scale and immediate analgesic effect, acupotomy did not have statistically significant results compared to other treatment methods. meta-analysis of electro-acupuncture and acupotomy showed no significant results. Conclusions When acupotomy is applied as a treatment for piriformis muscle syndrome, it is more effective than nerve block and acupuncture. but most of the studies have been judged as 'unclear' in the risk of bias assessment. Due to characteristics of treatment group and control group's intervention, It is judged that the blinding of the participant was not properly implemented. Therefore, it is considered that high-quality studies are necessary to supplement the problems in the future.

• International Journal of Computer Science & Network Security
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• v.21 no.6
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• pp.312-318
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• 2021

Lack of knowledge and digital skills is a threat to the information security of the state and society, so the formation and development of organizational culture of information security is extremely important to manage this threat. The purpose of the article is to assess the state of information security of the state and society. The research methodology is based on a quantitative statistical analysis of the information security culture according to the EU-27 2019. The theoretical basis of the study is the theory of defense motivation (PMT), which involves predicting the individual negative consequences of certain events and the desire to minimize them, which determines the motive for protection. The results show the passive behavior of EU citizens in ensuring information security, which is confirmed by the low level of participation in trainings for the development of digital skills and mastery of basic or above basic overall digital skills 56% of the EU population with a deviation of 16%. High risks to information security in the context of damage to information assets, including software and databases, have been identified. Passive behavior of the population also involves the use of standard identification procedures when using the Internet (login, password, SMS). At the same time, 69% of EU citizens are aware of methods of tracking Internet activity and access control capabilities (denial of permission to use personal data, access to geographical location, profile or content on social networking sites or shared online storage, site security checks). Phishing and illegal acquisition of personal data are the biggest threats to EU citizens. It have been identified problems related to information security: restrictions on the purchase of products, Internet banking, provision of personal information, communication, etc. The practical value of this research is the possibility of applying the results in the development of programs of education, training and public awareness of security issues.

• The Journal of Internal Korean Medicine
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• v.42 no.3
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• pp.340-350
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• 2021

Objectives: Hand-foot syndrome (HFS) is a common adverse effect of chemotherapy in cancer patients. This review synthesizes research results to assess the effect of traditional Korean medicine (TKM) on HFS in cancer patients. Methods: Four databases (PubMed, The Cochrane Central Register of Controlled Trials, Research Information Sharing Service, China National Knowledge Infrastructure) were searched for randomized controlled trials (RCTs) to assess the effects of TKM on HFS. The effects and quality of RCTs were assessed with the Cochrane risk of bias (ROB) tool. Results: Six RCTs met our study criteria. In all six, TKM showed improvement in HFS symptoms as well as quality of life scores when compared to the control group. However, the methodological quality of RCTs was relatively low due to the unclear or high ROB. Conclusions: TKM would be helpful to patients with HFS after chemotherapy. To clarify the clinical efficacy of TKM, well-designed studies are required in the future.

• Journal of Convergence for Information Technology
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• v.9 no.10
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• pp.170-175
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• 2019

This study aimed to analyse the effects of academic self-efficacy of beauty specialized high school students on learning flow and provide basic data needed for their learning instruction. For the purpose, this study surveyed 327 students of beauty specialized high schools located in B metropolitan city and N city. The responses were analysed with the use of the SPSS WIN 21.0. The results are presented as follows: Academic self-efficacy had a significant effect on learning flow and in particular, self-control efficacy and task difficulty preference were important factors. Based on the results above, it is suggested that teachers should present data that is properly converged by techniques and academic knowledge according to levels and steps so that students can have experiences of academic achievements and be encouraged to have higher self-efficiency.

• The Journal of Pediatrics of Korean Medicine
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• v.33 no.4
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• pp.1-25
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• 2019

Objectives The purpose of this study is to analyze the trends of Chinese clinical research in the last 5 years of Chinese herbal medicine treatment for anorexia in children, and to find ways to utilize the diagnostic criteria and herbal medicine treatment for children who have anorexia in Korea. Methods The authors searched literatures using China National Knowledge Infrastructure published from January 1, 2015 to June 18, 2019. Selected literatures were collected in order of recent publication year. And then, demographic data, duration of illness, intervention, treatment period, outcome, and adverse events were analyzed. In addition, the diagnostic criteria for anorexia in children are categorized and presented in chart. Results A total of 50 papers were included in the analysis of this study. In the selected studies, the most commonly used diagnostic criteria for anorexia in children were ${\ll}$Zhu Futang Practice of Pediatrics${\gg}$ in Western medicine and ${\ll}$Diagnostic and therapeutic criteria for TCM syndromes${\gg}$ in traditional Chinese medicine. As a result, in all the studies reporting total efficacy, the total effective rate of the treatment group treated with herbal medicine was significantly higher than that of the control group. Also, appetite recovery rate and weight gain were significantly higher, gastric emptying time and appetite recovery time were significantly shorter in the treatment group. Conclusions Herbal medicine treatment can help improve anorexia in children. In Korea, diagnostic criteria for anorexia in children should be established. In addition, criteria should be established to evaluate the effectiveness of herbal medicine treatment.

• Journal of Engineering Education Research
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• v.24 no.1
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• pp.24-33
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• 2021

As online learning continues to be extended, many engineering colleges are engaged in online learning activities. One of the core competencies required of engineering students in a knowledge-convergence society is communication skills. Online discussion activities are frequently used in educational field to improve communication skills. Efforts are being made to provide visual dashboards in online discussion activity systems to more effectively support online discussion activities. However there is less qualitative studies on students' experience in discussion activities. The purpose of this study is to explore the experience of engineering students participating in discussion activities using online discussion systems and visual dashboards. We interviewed 15 students who participated in online discussion activities to achieve their research objectives about their experience in utilizing the online discussion system, their perception of visual dashboards, and their experience in discussion activities. As a result of the study, students' perception of the use of the online discussion activity system, the visual dashboard, and the perception of a sense of social presence were understood. To be more effective in providing tool support, such as discussion activity systems and visual dashboards in online discussion activities, instructors need to understand the nature of learners' online discussion activities.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.20 no.2
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• pp.91-108
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• 2010

Universities are one of leading R&D institutes, however, their scarce security investment allows research information to leak outside. This paper proposes methods for improving security level of academic institutes to protect research information by analyzing security awareness and activities. To do that, we verified the current status of information security and awareness level by analyzing the survey which was conducted for a member of Seoul National University. As a result of statistical analysis using correlation, analysis of variance, multi regression and so on, we concluded that it is essential to improve security awareness, activities, professor's security level and management process for research labs. Thus, we suggest the following methods, security awareness and knowledge development through education, security management for research labs through provision, introduction of data protection softwares and physical control of visitors which are to be adopted to improve security level.