• Korean Journal of Radiology
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• 제1권4호
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• pp.191-197
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• 2000

Because US plays a key role in the initial evaluation of hepatic hemangiomas, knowledge of the entire spectrum of US appearances of these tumors is important. Most hemangiomas have a distinctive US appearance, and even with those with atypical appearances on conventional gray-scale US, specific diagnoses can be made using pulse-inversion harmonic US with contrast agents. In this essay, we review the spectrum of US appearances of hepatic hemangiomas on conventional gray-scale, power Doppler, and pulse-inversion harmonic US with contrast agents.

• Clinical Endoscopy
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• 제56권4호
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• pp.510-520
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• 2023

Background/Aims: We aimed to investigate (1) promising clinical findings for the recognition of focal type autoimmune pancreatitis (FAIP) and (2) the impact of endoscopic ultrasound (EUS)-guided tissue acquisition (EUS-TA) on the diagnosis of FAIP. Methods: Twenty-three patients with FAIP were involved in this study, and 44 patients with resected pancreatic ductal adenocarcinoma (PDAC) were included in the control group. Results: (1) Multivariate analysis revealed that homogeneous delayed enhancement on contrast-enhanced computed tomography was a significant factor indicative of FAIP compared to PDAC (90% vs. 7%, p=0.015). (2) For 13 of 17 FAIP patients (76.5%) who underwent EUS-TA, EUS-TA aided the diagnostic confirmation of AIPs, and only one patient (5.9%) was found to have AIP after surgery. On the other hand, of the six patients who did not undergo EUS-TA, three (50.0%) underwent surgery for pancreatic lesions. Conclusions: Homogeneous delayed enhancement on contrast-enhanced computed tomography was the most useful clinical factor for discriminating FAIPs from PDACs. EUS-TA is mandatory for diagnostic confirmation of FAIP lesions and can contribute to a reduction in the rate of unnecessary surgery for patients with FAIP.

• 한국정보통신학회논문지
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• 제19권6호
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• pp.1296-1300
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• 2015

본 논문에서는 초음파 영상에서 결절종을 추출하는 방법을 제안한다. 제안된 방법은 초음파 영상에서 퍼지 스트레칭 기법을 적용하여 명암 대비를 증가시킨다. 퍼지 스트레칭 기법이 적용된 초음파 영상에서 퍼지 이진화 기법을 적용한다. 퍼지 이진화 기법이 적용된 영상에서 잡음 영역을 제거하기 위해 8방향 윤곽선 추적 기법을 적용한후, 결절종 후보 영역을 추출한다. 추출된 결절종 후보 영역에서 침식과 팽창 기법을 적용한 후, labelling 기법을 적용하여 결절종이 형태학적으로 타원 형태를 가지는 정보를 이용하여 결절종 영역을 추출한다. 제안된 방법을 결절종 초음파 영상을 대상으로 실험한 결과, 결절종 초음파 영상에서 결절종 영역이 비교적 정확히 추출되는 것을 확인할 수 있었다.

• 대한의용생체공학회:의공학회지
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• 제29권2호
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• pp.122-131
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• 2008

For B-mode ultrasound images, we propose an image enhancement algorithm based on a multi-resolution approach, which consists of edge enhancing and noise reducing procedures. Edge enhancement processing is applied sequentially to coarse-to-fine resolution images obtained from wavelet-transformed data. In each resolution, the structural features of each pixel are examined through eigen analysis. Then, if a pixel belongs to an edge region, we perform two-step filtering: that is, directional smoothing is conducted along the tangential direction of the edge to improve continuity and directional sharpening is conducted along the normal direction to enhance the contrast. In addition, speckle noise is alleviated by proper attenuation of the wavelet coefficients of the homogeneous regions at each band. This region-based speckle-reduction scheme is differentiated from other methods that are based on the magnitude statistics of the wavelet coefficients. The proposed algorithm enhances edges regardless of changes in the resolution of an image, and the algorithm efficiently reduces speckle noise without affecting the sharpness of the edge. Hence, compared with existing algorithms, the proposed algorithm considerably improves the subjective image quality without providing any noticeable artifacts.

• 한국정보통신학회논문지
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• 제19권11호
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• pp.2540-2545
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• 2015

본 논문에서는 복부 초음파 영상에서 충수를 추출하는 방법을 제안한다. 제안된 충수 추출 방법은 복부 초음파 영상에서 명암 대비를 강조하기 위해 Ends_in Search Stretching 기법을 적용하고, Max-Min 이진화, 영역 레이블링, 잡음제거, Cubic Spline 보간법을 적용하여 복부 근육의 하단 근막 부분을 추출한다. 그리고 초음파 영상에서 추출된 근막 영역을 제거한 후, ART2 알고리즘을 적용하여 충수를 추출한다. 제안된 방법을 초음파 영상에 적용한 결과, 제안된 충수 추출 방법이 효율적으로 충수가 추출되는 것을 영상의학과 전문의를 통하여 확인하였다.

• 한국멀티미디어학회논문지
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• 제20권1호
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• pp.43-50
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• 2017

According to living environment, the number of deaths due to thyroid diseases increased. In this paper, we proposed an algorithm for recognizing a thyroid detection using texture analysis based on shape, gray level co-occurrence matrix and gray level run length matrix. First of all, we segmented the region of interest (ROI) using active contour model algorithm. Then, we applied a total of 18 features (5 first order descriptors, 10 Gray level co-occurrence matrix features(GLCM), 2 Gray level run length matrix features and shape feature) to each thyroid region of interest. The extracted features are used as statistical analysis. Our results show that first order statistics (Skewness, Entropy, Energy, Smoothness), GLCM (Correlation, Contrast, Energy, Entropy, Difference variance, Difference Entropy, Homogeneity, Maximum Probability, Sum average, Sum entropy), GLRLM features and shape feature helped to distinguish thyroid benign and malignant. This algorithm will be helpful to diagnose of thyroid nodule on ultrasound images.

• 말소리와 음성과학
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• 제11권1호
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• pp.19-27
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• 2019

Lateral approximants are well known as having complex articulatory characteristics, which vary cross-linguistically, across speakers, and across utterances. However, less attention has been paid to the articulation of Korean laterals, which do not contrast with a rhotic and may thus exhibit greater-than-normal variability. The focus of this study is to investigate the general articulatory characteristics of the Korean lateral [l] as well as the articulatory variation using novel 3D ultrasound imaging methods. The results of this study revealed significant between-speaker variation and some vowel-dependent variation with regard to the articulation of the Korean lateral [l], which has not been reported previously. Even though all participants in this study showed an anterior occlusion, the place of articulation and the size of the occlusion varied greatly across speakers. The data also revealed that left-right asymmetry is present in the articulation of the Korean lateral. The individual variation of the Korean lateral [l] suggests that it has a large articulatory-acoustic space for variation, since it has no contrasting sound that causes perceptual confusion.

• 대한방사선기술학회지:방사선기술과학
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• 제38권3호
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• pp.213-220
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• 2015

본 연구는 3차원 입체정위 유방생검술의 정확도를 알아보고, 심부침생검을 이용하여 Stereotactic biopsy과 Sonoguided biopsy의 정확도와 정밀도를 평가하고자 한다. Stereotactic QC phantom을 이용하여 실제 5개의 target 위치로 3D sterotactic machine의 정확도를 측정하고, CT장비로 Scan하여 실측을 구해 X, Y, Z의 길이의 정밀도를 비교한다. 유방조직과 유사하게 제작한 Agar power phantom을 이용하여 5개의 각기 다른 needle tip Target을 통해 3D sterotactic machine과 2D ultrasound machine의 정확도를 비교하고, Z축을 장비별로 실측하여 정밀도와 신뢰도를 비교하며, 6개의 모조병소 Target을 심어놓은 Medical application phantom으로 표적하여 육안검사와 Specimen검사를 통해 정확도를 확인하였다. Stereotactic QC phantom으로 측정한 3D sterotactic machine의 정확도는 100%였으며, CT와 비교한 정밀도는 X, Y, Z축이 모두 p>0.05로 나타났다. Agar powder phantom으로 측정한 두 장비의 정확도는 100%의 정확도를 보였으며, CT와 두 장비 사이에는 p > 0.05로 차이가 없었다. 그러나 2명의 방사선사가 측정한 신뢰도분석에서 3D sterotactic machine은 ICC가 0.954였고, 2D ultrasound machine은 0.785로 2D ultrasound machine이 술자에 따라 차이가 있었다. Medical application phantom의 실험에서 3D sterotactic machine은 Sliced boneless ham을, 2D ultrasound machine은 small chalk powder group를 찾을 수 없었다. Phantom을 이용한 3차원 입체정위 유방생검술의 정확성은 우수하게 나타났고, 인체조직과 비슷한 Agar powder phantom과 유방 조직과 비슷한 Medical application phantom을 이용하여 Stereotactic biopsy과 Sonoguided biopsy의 정확도와 정밀도 모두 우수하게 나타났다. 또한 Medical application phantom의 심부침생검의 정확성 평가에서 각 검사에 따라 생검 표본이 병소의 형태에 따라 상이하게 채취되었고, 3차원 입체정위 유방생검술의 재현성이 유방 초음파검사보다 술자의 영향없이 우수하였다.

• Korean Journal of Radiology
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• 제20권5호
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• pp.759-772
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• 2019

Objective: To investigate the value of ultrasound (US) microflow assessment in distinguishing malignant from benign solid breast masses as well as the association between US parameters and histologic microvessel density (MVD). Materials and Methods: Ninety-eight breast masses (57 benign and 41 malignant) were examined using Superb Microvascular Imaging (SMI) and contrast-enhanced US (CEUS) before biopsy. Two radiologists evaluated the quantitative and qualitative vascular parameters on SMI (vascular index, morphology, distribution, and penetration) and CEUS (time-intensity curve analysis and enhancement characteristics). US parameters were compared between benign and malignant masses and the diagnostic performance was compared between SMI and CEUS. Subgroup analysis was performed according to lesion size. The effect of vascular parameters on downgrading Breast Imaging Reporting and Data System (BI-RADS) category 4A masses was evaluated. The association between histologic MVD and US parameters was analyzed. Results: Malignant masses were associated with a higher vascular index (15.1 ± 7.3 vs. 5.9 ± 5.6), complex vessel morphology (82.9% vs. 42.1%), central vascularity (95.1% vs. 59.6%), penetrating vessels (80.5% vs. 31.6%) on SMI (all, p < 0.001), as well as higher peak intensity (37.1 ± 25.7 vs. 17.0 ± 15.8, p < 0.001), slope (10.6 ± 11.2 vs. 3.9 ± 4.2, p = 0.001), area (1035.7 ± 726.9 vs. 458.2 ± 410.2, p < 0.001), hyperenhancement (95.1% vs. 70.2%, p = 0.005), centripetal enhancement (70.7% vs. 45.6%, p = 0.023), penetrating vessels (65.9% vs. 22.8%, p < 0.001), and perfusion defects (31.7% vs. 3.5%, p < 0.001) on CEUS (p ≤ 0.023). The areas under the receiver operating characteristic curve (AUCs) of SMI and CEUS were 0.853 and 0.841, respectively (p = 0.803). In 19 masses measuring < 10 mm, central vascularity on SMI was associated with malignancy (100% vs. 38.5%, p = 0.018). Considering all benign SMI parameters on the BI-RADS assessment, unnecessary biopsies could be avoided in 12 category 4A masses with improved AUCs (0.500 vs. 0.605, p < 0.001). US vascular parameters associated with malignancy showed higher MVD (p ≤ 0.016). MVD was higher in malignant masses than in benign masses, and malignant masses negative for estrogen receptor or positive for Ki67 had higher MVD (p < 0.05). Conclusion: US microflow assessment using SMI and CEUS is valuable in distinguishing malignant from benign solid breast masses, and US vascular parameters are associated with histologic MVD.

• 대한방사선기술학회지:방사선기술과학
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• 제46권6호
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• pp.475-484
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• 2023

This study aimed to compare filters for reducing speckle noise in ultrasound images using clinical liver images. We acquired the clinical liver ultrasound images, and noisy images were obtained by adding 0.01, 0.05, 0.10, and 0.50 intensity levels of speckle noise to the liver images. The Wiener filter, median modified Wiener filter, gamma filter, and Lee filter were designed for the noisy images by setting window sizes at 3×3, 5×5, and 7×7. The coefficient of variation (COV) and contrast to noise ratio (CNR) were calculated to evaluate noise reduction and various filters. Moreover, the filter with the highest image quality was selected and quantitatively compared to a noisy image. As a result, COV and CNR showed the noise improved result when the Lee filter was applied. Furthermore, the Lee filter image with a window size of 7×7 was noted to possess approximately a minimum of 1.28 to a maximum of 3.38 times better COV and a minimum of 2.18 to a maximum of 5.50 times better CNR than the noisy image. In conclusion, we confirmed that the Lee filter was effective in reducing speckle noise and proved that an appropriate window size needs to be set considering blurring.