• 한국노년학
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• v.40 no.1
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• pp.147-161
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• 2020

The purpose of this research is to investigates 10-year trajectories of cognitive functions among older adults in their 70s to understand changes in cognitive functions as a continuum until very late life. This study also examines differences in trajectories of cognitive functions by gender and by changes in marital status, especially widowhood. Among participants of the Korean Longitudinal Study of Ageing(KLoSA), the sample of this study includes 800 older adults in their 70s during the first study wave (2006) and those who reported their cognitive functions for six consecutive study waves (2006, 2008, 2010, 2012, 2014, and 2016). The analyses were conducted in two steps. First, we conducted Latent Class Growth Analyses(LCGA) to investigated heterogeneous trajectories of cognitive functions in 10 years. Then, we performed multinomial logistic regression. Three heterogeneous trajectories of cognitive functions were identified. One group of 48.7% of older adults showed high cognitive function at baseline and maintained it over 10 years. Second group of 14.7% of older adults reported low cognitive function scores at baseline and showed continuous decline over time. Third group of 36.6% were showed mid-level cognitive functions and maintained their functions over time. We also found significant gender differences but not significant differences in marital status when we consider both in our model; however, the we found significant differences in changes in marital status when we did not consider gender in the model. The results suggest that the importance of considering dynamics of gender and changes in marital status to understand changes in cognitive functions in later life.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.24 no.1
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• pp.1-7
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• 2011

In this paper, based on an isogeometric approach, we have developed a shape design optimization method for plane elasticity problems subjected to design-dependent loads. The conventional shape optimization using the finite element method has some difficulties in the parameterization of geometry. In an isogeometric analysis, however, the geometric properties are already embedded in the B-spline basis functions and control points so that it has potential capability to overcome the aforementioned difficulties. The solution space for the response analysis can be represented in terms of the same NURBS basis functions to represent the geometry, which yields a precise analysis model that exactly represents the normal and curvature depending on the applied loads. A continuum-based isogeometric adjoint sensitivity is extensively derived for the plane elasticity problems under the design-dependent loads. Through some numerical examples, the developed isogeometric sensitivity analysis method is verified to show excellent agreement with finite difference sensitivity.

• Composites Research
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• v.30 no.5
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• pp.323-330
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• 2017

In this study, multiscale analysis in which the information obtained from molecular dynamics simulation is applied to the continuum mechanics level is conducted to investigate the effects of clustering of silicon carbide nanoparticles reinforced into polypropylene matrix on mechanical behavior of nanocomposites. The elastic behavior of polymer nanocomposites is observed for various states of nanoparticulate agglomeration according to the model reflecting the degradation of interphase properties. In addition, factors which mainly affect the mechanical behavior of the nanocomposites are identified, and new index 'clustering density' is defined. The correlation between the clustering density and the elastic modulus of nanocomposites is understood. As the clustering density increases, the interfacial effect decreased and finally the improvement of mechanical properties is suppressed. By considering the random distribution of the nanoparticles, the range of elastic modulus of nanocomposites for same value of clustering density can be investigated. The correlation can be expressed in the form of exponential function, and the mechanical behavior of the polymer nanocomposites can be effectively predicted by using the nanoparticulate clustering density.

• Korean Journal of Biological Psychiatry
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• v.8 no.1
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• pp.20-36
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• 2001

The debate about whether depressive disorders should be divided into categories or arrayed along a continuum has gone for decade, without resolution. In our review, there is more evidence consistent with the spectrum concept than there is with the idea that depressive disorders constitute discrete clusters marked by relatively discontinuous boundaries. First, "depression spectrum", "is there a common genetic factors in bipolar and unipolar affective disorder", "threshold model of depression" and "bipolar spectrum disorder" are reviewed. And, a new subtype of depression is so called SeCA depression that is a stressor-precipitated, cortisol-induced, serotonin-related, anxiety/aggression-driven depression. SeCA depression is discussed. But, there is with the idea that depressive disorders constitute discrete subtypes marked by relatively discontinuous boundaries. This subtypes of depressive disorder were reviewed from a variety of theoretical frames of reference. The following issues are discussed ; Dexamethasone suppression test(DST), TRH stimulation test, MHPG, Temperament Character Inventory(TCI), and heart rate variability(HRV).

• Journal of KIISE:Computer Systems and Theory
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• v.32 no.1
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• pp.29-38
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• 2005

The fluid animation procedure consists of physical simulation and visual rendering. In the physical simulation of fluids, the most frequently used practices are the numerical simulation of fluid particles using particle dynamics equations and the continuum analysis of flow via Wavier-Stokes equation. Particle dynamics method is fast in calculation, but the resulting fluid motion is conditionally unrealistic The method using Wavier-Stokes equation, on the contrary, yields lifelike fluid motion when properly conditioned, yet the complexity of calculation restrains this method from being used in real-time applications. Global illumination is generally successful in producing premium-Duality rendered images, but is also excessively slow for real-time applications. In this paper, we propose a rapid fluid animation method incorporating enhanced particle dynamics simulation method and pre-integrated volume rendering technique. The particle dynamics simulation of fluid flow was conducted in real-time using Lennard-Jones model, and the computation efficiency was enhanced such that a small number of particles can represent a significant volume. For real-time rendering, pre-integrated volume rendering method was used so that fewer slices than ever can construct seamless inter-laminar shades. The proposed method could successfully simulate and render the fluid motion in real time at an acceptable speed and visual quality.

• Journal of Korean Tunnelling and Underground Space Association
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• v.6 no.4
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• pp.291-302
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• 2004

Blast-induced anisotropic rock damage around a blast-hole was analyzed by a using numerical method with user-defined subroutine based on continuum damage mechanics. Anisotropic blasting pressure was evaluated by applying anisotropic ruck characteristics to analytical solution which is a function of explosive and rock properties. Anisotropic rock damage was evaluated by applying the proposed anisotropic blasting pressure. Blast-induced isotropic rock damage was also analyzed. User-defined subroutines to solve anisotropic and isotropic damage model were coded. Initial rock damages in natural ruck were considered in anisotropic and isotropic damage models. Blasting pressure and elastic modulus of rock were major influential parameters from parametric analysis results of isotropic rock damage. From the results of anisotropic rock damage analysis, blasting pressure was the most influential parameter. Anisotropic rock damage area in horizontal direction was approximately 34% larger and about 12% smaller in vertical direction comparing with isotropic rock damage area. Isotropic rock damage area under fully coupled charge condition was around 30 times larger than that under decoupled charge condition. Blasting pressure under fully coupled charge condition was estimated to be more than 10 times larger than that of decoupled charge condition.

• Journal of The Korean Astronomical Society
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• v.50 no.6
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• pp.167-178
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• 2017

We present a study of the inexplicit connection between radio jet activity and ${\gamma}$-ray emission of BL Lacertae (BL Lac; 2200+420). We analyze the long-term millimeter activity of BL Lac via interferometric observations with the Korean VLBI Network (KVN) obtained at 22, 43, 86, and 129 GHz simultaneously over three years (from January 2013 to March 2016); during this time, two ${\gamma}$-ray outbursts (in November 2013 and March 2015) can be seen in ${\gamma}$-ray light curves obtained from Fermi observations. The KVN radio core is optically thick at least up to 86 GHz; there is indication that it might be optically thin at higher frequencies. To first order, the radio light curves decay exponentially over the time span covered by our observations, with decay timescales of $411{\pm}85$ days, $352{\pm}79$ days, $310{\pm}57$ days, and $283{\pm}55$ days at 22, 43, 86, and 129 GHz, respectively. Assuming synchrotron cooling, a cooling time of around one year is consistent with magnetic field strengths $B{\sim}2{\mu}T$ and electron Lorentz factors ${\gamma}$ ~ 10 000. Taking into account that our formal measurement errors include intrinsic variability and thus over-estimate the statistical uncertainties, we find that the decay timescale ${\tau}$ scales with frequency ${\nu}$ like ${\tau}{\propto}{\nu}^{-0.2}$. This relation is much shallower than the one expected from opacity effects (core shift), but in agreement with the (sub-)mm radio core being a standing recollimation shock. We do not find convincing radio flux counterparts to the ${\gamma}$-ray outbursts. The spectral evolution is consistent with the 'generalized shock model' of Valtaoja et al. (1992). A temporary increase in the core opacity and the emergence of a knot around the time of the second ${\gamma}$-ray event indicate that this ${\gamma}$-ray outburst might be an 'orphan' flare powered by the 'ring of fire' mechanism.

• Journal of Home Health Care Nursing
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• v.2
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• pp.5-18
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• 1995

While the socioeonomic status of Koreas has been dramatically increasing in recent years, chronic and geriatric diseases have also been on the rise, bringing about many changes in our health care system. The basic goals of the home health care are to reduce health care costs, to increase the attrition rate in general hospitals, and to care for patients effectively and conveniontly at home. The purpose of this paper is to review and examine the current status of the home health care in Korea throughout the reports, surveys, other informations and education system of home health nurse. We identified the various types of home health care services programs, such as hospital-based home health care operated in public sector(demonstration project) and community-based home health care in health centers or in private sector, that is, Korean Nurse Association. Hospital based home heatlh care model was established as an alternative to traditional in-patiet services. Quality assurance and client satisfaction is an important measure of care received and establishment of payment and reimbursement for home health care services is important in promotng the home health care. We found out a fee-per-visit system composed of three kinds of fees : a basic service fee(16,000 Won), a travel fee(5,000 Won), and per-service fees (variables). Like fees paid for in-patient care, insureds pay 20% and insurers pay 80% of the basic and per-service fee. The travel fee is borne totally by the insured. Home health care continues to be viewed as not only the most preferred way to provide care to clients, but also the most cost effective. Home health care is that component of a continuum of comprehensive health care whereby health services are provided to individuals and families in their places of residence for the purpose of promoting, maintaining, or restoring health, or of maximizing the level of independence, while minimizing illness. Services appropriate to the needs of the individual patient and family should be planned and provided, nursing is to be a force for positive change and enhanced the nursing professionalism. Whatever type of involvement of home health care, it is essential to remember that home health care is highly service-oriented and highly touch health car deilvery system.

• Journal of Wetlands Research
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• v.16 no.2
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• pp.213-220
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• 2014

Recently, river maintenance is change due to concern for the environment increases. Thus, the river restoration and river environment is best part of river maintenance. In case of Korea, existing river is improvement straightly for flood control and transportation. When the stream channel is straightly, maintain stability is important. Thus, construction of levees along the river. The various river structures for the purpose of flood control and transportation are inhibit factors of longitudinal and lateral connectivity. Connectivity is defined as the maintenance of lateral, longitudinal, and vertical pathways for biological, hydrological, and physical processes. Long-term point of view, increased connectivity is very important for a healthy ecosystem composition. As the first step of river restoration, this study described theory and concept of river continuum and the numerical model was applied to a real topography to simulate the flow analysis with or without segregated and blocked space in the Mankyung river. The results of this study can be utilized to develop the watershed connectivity assessments methods in order to the river restoration.

• Korean Journal of Radiology
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• v.23 no.1
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• pp.89-100
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• 2022

Objective: To improve the N biomarker in the amyloid/tau/neurodegeneration system by radiomics and study its value for predicting cognitive progression in individuals with mild cognitive impairment (MCI). Materials and Methods: A group of 147 healthy controls (HCs) (72 male; mean age ± standard deviation, 73.7 ± 6.3 years), 197 patients with MCI (114 male; 72.2 ± 7.1 years), and 128 patients with Alzheimer's disease (AD) (74 male; 73.7 ± 8.4 years) were included. Optimal A, T, and N biomarkers for discriminating HC and AD were selected using receiver operating characteristic (ROC) curve analysis. A radiomics model containing comprehensive information of the whole cerebral cortex and deep nuclei was established to create a new N biomarker. Cerebrospinal fluid (CSF) biomarkers were evaluated to determine the optimal A or T biomarkers. All MCI patients were followed up until AD conversion or for at least 60 months. The predictive value of A, T, and the radiomics-based N biomarker for cognitive progression of MCI to AD were analyzed using Kaplan-Meier estimates and the log-rank test. Results: The radiomics-based N biomarker showed an ROC curve area of 0.998 for discriminating between AD and HC. CSF Aβ42 and p-tau proteins were identified as the optimal A and T biomarkers, respectively. For MCI patients on the Alzheimer's continuum, isolated A+ was an indicator of cognitive stability, while abnormalities of T and N, separately or simultaneously, indicated a high risk of progression. For MCI patients with suspected non-Alzheimer's disease pathophysiology, isolated T+ indicated cognitive stability, while the appearance of the radiomics-based N+ indicated a high risk of progression to AD. Conclusion: We proposed a new radiomics-based improved N biomarker that could help identify patients with MCI who are at a higher risk for cognitive progression. In addition, we clarified the value of a single A/T/N biomarker for predicting the cognitive progression of MCI.