• Korean Journal of Veterinary Research
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• v.61 no.2
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• pp.12.1-12.9
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• 2021

The mosquito-borne pathogen Zika virus may result in neurological disorders such as Guillain-Barré syndrome and microcephaly. The virus is classified as a member of the Flaviviridae family and its wide spread in multiple continents is a significant threat to public health. So, there is a need to develop animal models to examine the pathogenesis of the disease and to develop vaccines. To examine the clinical profile during Zika virus infection, we infected neonatal and adult wild-type mice (C57BL/6 and Balb/c) and compared the clinical signs of African-lineage strain (MR766) and Asian-lineage strain (PRVABC59, MEX2-81) of Zika virus. Consistent with previous reports, eight-week-old female Balb/c mice infected with these viral strains showed no changes in body weight, survival rate, and neurologic signs, but demonstrated increases in the weights of spleens and hearts. However, one-day-old neonates showed significantly lower survival rate and body weight with the African-lineage strain than the Asian-lineage strain. These results confirmed the pathogenic differences between Zika virus strains. We also evaluated the clinical responses in neonatal and adult mice of different strains. Our findings suggest that these are useful mouse models for characterization of Zika virus for vaccine development.

• Journal of Distribution Science
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• v.20 no.10
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• pp.39-50
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• 2022

Purpose: This report aimed to review the literature on the research topic "Imports and exports between Colombia and Asian countries in the framework of logistics processes in international trade" of the last ten years. Research design, data and methodology: Documents indexed in the Web of Science metasearch engine were used as a source of information. The 500 most relevant downloaded in bibTex format were worked on and their processing was carried out using the statistical software Excel and R, through the Bibliometrix package. Results: The results indicate that the country that makes the most contributions to the research area is the United States (274), the author that publishes the most is Bahmani-Oskooee M., with (11) research, 424 of the documents found are journal articles, and the institution that contributes the most in this area is the University of Wisconsin. Conclusions: It is concluded that scientific production within the framework of international trade between Asia and Colombia has had a notable increase, which can be explained by the opening of both continents as strategic allies and the new vision of logistics processes taking advantage of the strategic location of countries within the Pacific Ocean.

• International journal of advanced smart convergence
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• v.11 no.3
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• pp.132-141
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• 2022

We look at the rocket life stages of NaverZ's metaverse platform scaling and investigate the ignition and scale-up stage of its metaverse platform brand, Zepeto based on the Rocket Model (RM). The results are derived as follows: Firstly, NaverZ shows the event strategy by collaborating with K-pops, the piggybacking strategy by utilizing other SNSs, and the VIP strategy by investing in game and entertainment content genres in the 'attract' function. In the second 'match' function, based on the matching rule of Zepeto, the users can generate their own characters and "World" with Zepeto Studio. However, for strengthening the matching quality, NaverZ is investing in the artificial intelligence (AI) based companies consistently. In the 'connect' function, NaverZ's maximization of the positive interaction is possible by inducing feed activities in Zepeto & other SNSs and by uploading attractive content for viral effects in the ignition. For facilitating this, NaverZ expands the scale to other continents like Southeast Asia and Middle East with the localization strategy inclusive investment. Lastly, in the 'transact' function, based on three monetization experiments like Coin & ZEM, user generated content (UGC) fee, and advertising revenue in the ignition, NaverZ starts to invest in NFT platforms and abroad blockchain companies.

• Genomics & Informatics
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• v.21 no.2
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• pp.26.1-26.9
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• 2023

Stevens-Johnson syndrome (SJS) produces a severe hypersensitivity reaction caused by Herpes simplex virus or mycoplasma infection, vaccination, systemic disease, or other agents. Several studies have investigated the genetic susceptibility involved in SJS. To provide further genetic insights into the pathogenesis of SJS, this study prioritized high-impact, SJS-associated pathogenic variants through integrating bioinformatic and population genetic data. First, we identified SJS-associated single nucleotide polymorphisms from the genome-wide association studies catalog, followed by genome annotation with HaploReg and variant validation with Ensembl. Subsequently, expression quantitative trait locus (eQTL) from GTEx identified human genetic variants with differential gene expression across human tissues. Our results indicate that two variants, namely rs2074494 and rs5010528, which are encoded by the HLA-C (human leukocyte antigen C) gene, were found to be differentially expressed in skin. The allele frequencies for rs2074494 and rs5010528 also appear to significantly differ across continents. We highlight the utility of these population-specific HLA-C genetic variants for genetic association studies, and aid in early prognosis and disease treatment of SJS.

• Journal of the Korean Society for Railway
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• v.15 no.4
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• pp.334-342
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• 2012

It is connected with various gauges existing in Euro-Asian continents. Such differences impedes the operation seriously as on the contact of railway tracks of different gauge the cargo must be either transshipped or the running assemblies of rail vehicles must be exchanged. Those operations are costly, time-consuming and require extended infrastructure together with very expensive storage and transshipment facilities at border-crossing point. Moreover, those operations extend transportation time considerably. Therefore, effectiveness of railway transportation systems significantly depends on track gauge change 1435/1520mm, which connects with complicated handling-shifting operations. The paper concerns assessment of effectiveness in strategical rail systems with gauge changing. The paper presents short description of transport system with gauge changing and initial assessment of shifting technologies. Method of system assessment comparison based on Life Cycle Cost model is described here as well.

• Journal of Environmental Science International
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• v.10 no.6
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• pp.423-429
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• 2001

Satellite data, with sea surface temperature(557) by NOAA and sea level(SL) by Topex/poseidon, are used to estimate characteristics on the variations and correlations of 557 and SL in the East Asian Seas from January 1993 through May 1998. We found that there are two climatic characteristics in the East Asian seas the oceanic climate, the eastern sea of Japan, and the continental climate, the eastern sea of China, respectively. In the oceanic climate, the variations of SL have the high values in the main current of Kuroshio and the variations of 557 have not the remarkable seasonal variations because of the continuos compensation of warm current by Kuroshio. In the continental climate, SL has high variations in the estuaries(the Yellow River, the Yangtze River) with the mixing the fresh water and the saline water in the coasts of continent and 557 has highly the seasonal variations due to the climatic effect of continents. In the steric variations of summer, the eastern sea of Japan, the East China Sea and the western sod of Korea is increased the sea level about 10~20cm. But the Bohai bay in China have relatively the high values about 20~30cm due to the continental climate. generally the trends of SST and SL increased during all periods. That is say, the slopes of 557 and SL Is presented 0.29$^{\circ}C$/year and 0.84cm/year, respectively. The annual and semi-annual amplitudes have a remarkable variations in the western sea of Korea and the eastern sea of Japan. In the case of the annual peaks, there appeared mainly In the western sea of Korea and the eastern sea of .Japan because of the remarkable variations of SL associated with Kuroshio. But in the case of the semi-annual peaks, there appeared in the eastern sea of Japan by the influence of current, and in the western sea of Korea by the influence of seasonal temperature, respectively. From our results, it should be believed that 557 and SL gradually Increase in the East Asian seas concerning to the global warming. So that, it should be requested In the international co-operation against In the change of the abnormal climate.

• Korean Journal of Health Education and Promotion
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• v.23 no.5
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• pp.47-73
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• 2006

Objectives: This study aims to identify gaps between knowledge regarding migration and the spread of HIV/AIDS, to improve understanding of migrants with HIV/AIDS and their human rights, and to make suggestions for Korean policy makers to reform laws and policies towards granting migrants with HIV/AIDS more human rights and access to treatment and care. Methods: This study is based on an extensive literature review, questionnaire surveys and in-depth interviews from randomly selected 8 countries from 5 different continents: Japan from Asia; Australia from Oceania; Finland, Germany, Ireland and United Kingdom(UK) from Europe; and Canada and United States of America(USA) in North America. Results: This study has found that Korea has a discriminating policy regarding HIV/AIDS and foreigners. Classifying HIV/AIDS into a legal communicable disease, it requires a presentation of HIV/AIDS test results from foreigners wanting a long-term stay before entering. In principle, foreigners with HIV/AIDS cannot either enter or stay in Korea. If they are known infected with HIV/AIDS by any reason, they became to face an immediate deportation regardless of their sojourn statuses and purposes. Conclusion: With the results, this study suggests three reasons why Korean government needs to change the current HIV/AIDS policy on foreigners: 1) HIV-related travel restrictions have no public health justification, 2) its strict HIV/AIDS policy on foreigners could result in restriction on the mobility and migration of its people by the other countries, inversely, and 3) it needs to meet international guidelines and to observe conventions that international organizations suggest to maintain its status as a member of the international society.

• ALGAE
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• v.35 no.3
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• pp.213-224
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• 2020

The freshwater red algal genus Sheathia contains species with heterocortication (both bulbous and cylindrical cells covering the main axis) and homocortication (only cylindrical cells). When the genus was proposed, the species with heterocortication were revised, but all specimens with homocortication were assigned to Sheathia arcuata with the caveat that it may represent a species complex. Recent studies have described new species with homocortication and S. arcuata has been rendered paraphyletic. In the current study, new sequences of the rbcL and 5′ region of the cytochrome c oxidase subunit I markers were combined with previously published data to construct a robust phylogeny and circumscribe new species. Four new species, S. abscondita, S. californica, S. plantuloides, and S. transpacifica are proposed. Examination of morphological characters among homocorticate species show no diagnostic characters to distinguish among species, whereas S. plantuloides is only known from sporophytes (chantransia) so it lacks the typical morphological characters derived from the gametophytes for comparison. Although DNA sequence data would be needed to make a positive species identification, geography could be employed to narrow the identification to one or two species. The genus is geographically widespread having been recorded from oceanic islands and five continents, whereas the individual species typically occur on a single continent. With this study, the number of species recognized in Sheathia is raised to 17; seven heterocorticate and 10 homocorticate, making this genus one of the most species rich in the Batrachospermales. As well, the resulting phylogeny provides insights into the evolution of heterocortication in Sheathia.

• The Research Journal of the Costume Culture
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• v.19 no.3
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• pp.579-596
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• 2011

As a sport with artistic characteristics, figure skating draws upon important elements such as costumes, music, melody interpretation, and choreography. The combination of figure skating music and costume is an important influence on scoring, moreover, it forms some images and characteristics of the athlete. The purpose of this study is to consider and analyze the correlation between figure skating music and costumes. The study mostly focuses on the main international competitions from 2008 to 2010, such as the Winter World Figure Skating Championships, Four Continents Figure Skating Championships, Grand Prix of Figure Skating Final and gala shows of a single female and male and female pairs, ice dances of the medalists. The concepts and characteristics of figure skating music were examined collected the literature quotes internet sites, photos and video, clips through the homepage and internet sites. Focusing on the medalists of the main international competitions from 2008 to 2010, following the analysis results of figure skating by genre of music, the differences among classical music, pop music, movie music, musical music, folk music have been classified, and according to the features of music genres, the differences of items, colors, details and accessories of clothing were brought out. Depending on the features of music genres, figure skating costumes have been changed of items, colors, materials, details and accessories. Thus, the close correlation between the story of figure skating music and atmosphere has been analyzed. This study contributes to improve the completion of programs which is completed through the development of figure skating costumes design that is regarded specially for the artistic value.

• Korean Journal of Oriental Medicine
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• v.16 no.2
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• pp.65-73
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• 2010

This study is to discuss the content of Posangkimun on the whole and to report the understanding of Seokgok Lee Gyujoon on western civilization. Through the overall analysis of Posangkimun, it is found the following facts: 1. Posangkimun aroused interest of academic circles as it covered theories of western civilization. Most of the introduction to western civilization contained in the book is related to astronomy and geography. Seokgok criticized all the western theories on revolution of the earth, astronomy, continents and oceans on the ground that these theories were not congruous with the teaching of the Oriental sages. 2. Seokgok found the reasons why the West had led the East from 'nationalism' of the West. The nationalism mentioned here were more similar to 'democracy' in modern sense, or rather 'democratism'. What is specially noteworthy is that he did not find the reasons of western advancement from the spiritual issues not from the machine civilization. In this way, Seokgok could avoid the fallacy of throwing away traditional ideas to concentrate in western machine civilization. 3. The content of Posangkimun shows that Seokgok was a person with a very conservative view. Notwithstanding his inclination, he had good knowledge about western theories, most of which were gathered from newspapers and magazines at that time. It means that newspapers and magazines should be treated with more importance when studying Korean intellectuals in late Joseon period or during the time of Japanese forced occupation.