• Journal of Biomedical Engineering Research
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• v.45 no.1
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• pp.43-48
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• 2024

The prevalence of obesity and its complications is steadily increasing worldwide. It is essential to understand cellular level metabolism and microenvironment to treat diseases related to lipid metabolism. Mechanical loading can activate signaling pathway by stimulating cells, especially vibration loading known to inhibit adipogenesis, so it has been studied as a treatment for obesity. Also, vibration loading can affect the inside of the human body non-invasively. Another clue to reducing adipose tissue is browning, which means that white adipocytes changes to brown adipocyte. In this study, we design and developed a device that that can control cell-cell contact, and vibration simulation device. Using these two devices, we investigated responses of cells to vibration loading. Protein expression associated with browning and adipogenesis were analyzed. In conclusion, vibration loading can be transmitted through cell contact and loading applied to the cells can induce browning and inhibit adipogenesis of preadipocytes. These results suggest the possibility that vibrations could be a treatment for obesity.

• Tribology and Lubricants
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• v.17 no.5
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• pp.373-379
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• 2001

The problem of interest is formulating elastic contact problem of a layered semi-infinite solid in terms of Fourier integral. The plane strain problem is considered for a solid composed of homogeneous isotropic two layers with different mechanical properties. General solutions for the subsurface stress and deformation field of frictionless elastic bodies under normal loading using of Fourier transformation technique are obtained. The numerical results for the stress distribution of coated solid for some particular cases are given.

• Tribology and Lubricants
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• v.21 no.3
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• pp.136-141
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• 2005

Analytical model to calculate the contact fatigue life of rough surface is presented in this paper. The effect of surface roughness can be calculated by this model. Computational method and the theoretical basis are also discussed. Contact stresses are obtained by contact analysis of a semi-infinite solid based on the use of influence functions; the subsurface stress field is obtained using rectangular patch solutions. Mesoscopic multiaxial fatigue criterion which can yield satisfactory results for non-proportional loading is then applied to predict fatigue damage. Suitable counting method and damage rule were used to calculate the fatigue life of random loading caused by rough surface. As a result of analysis the relationship between the life and the roughness as well as the most probable depth of the crack initiation is calculated.

• International Journal of Concrete Structures and Materials
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• v.11 no.2
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• pp.343-363
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• 2017

The objective of this work was finding out the most advisable testing conditions for an effective and robust characterization of the tensile strength (TS) of concrete disks. The independent variables were the loading geometry, the angle subtended by the contact area, disk diameter and thickness, maximum aggregate size, and the sample compression strength (CS). The effect of the independent variables was studied in a three groups of experiments using a factorial design with two levels and four factors. The likeliest location where failure beginning was calculated using the equations that account for the stress-strain field developed within the disk. The theoretical outcome shows that for failure beginning at the geometric center of the sample, it is necessary for the contact angle in the loading setup to be larger than or equal to a threshold value. Nevertheless, the measured indirect tensile strength must be adjusted to get a close estimate of the uniaxial TS of the material. The correction depends on the loading geometry, and we got their mathematical expression and cross-validated them with the reported in the literature. The experimental results show that a loading geometry with a curved contact area, uniform load distribution over the contact area, loads projected parallel to one another within the disk, and a contact angle bigger of $12^{\circ}$ is the most advisable and robust setup for implementation of BT on concrete disks. This work provides a description of the BT carries on concrete disks and put forward a characterization technique to study costly samples of cement based material that have been enabled to display new and improved properties with nanomaterials.

• International Journal of Concrete Structures and Materials
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• v.1 no.1
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• pp.19-28
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• 2007

A dynamic constitutive damage model for reinforced concrete (RC) structures and formulations of blast loading for contact or near-contact charges are considered and adapted from literatures. The model and the formulations are applied to the input parameters needed in commercial finite element method (FEM) codes which is validated by the laboratory blast tests of RC slabs from literature. The results indicate that the dynamic constitutive damage model based on the damage mechanics and the blast loading formulations work well. The framework on the dynamic constitutive damage model and the blast loading equations can therefore be used for the simulation of failure of bridge components in engineering applications.

• Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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• 2003.11a
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• pp.291-298
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• 2003

Recently, load/unload(L/UL) process is applied to a computer information storage device due to its advantages such as lower power consumption, larger data zone, simpler fabrication of disk for no bumped parking zone, and rarer contact between the slider and media. An analysis of the transient motion for the slider is very important to design an air bearing surface (ABS) of the slider to secure the stable performance of the system. During the L/UL process, however, there are several issues occurred such as contact or collision between slider and media. Sometimes this will cause the system failure. In this study, the dynamics of the slider during the loading process are investigated through a numerical simulation using FEM analysis and experiment.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1997.10a
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• pp.87-94
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• 1997

The circular plate resting on Boussinesq's half-space model under axisymmetric loading is studied by a finite element procedure to evaluate the distribution of contact pressure between plate and elastic half-space. The displacement of half-space due to axisymmetric surface loading can be evaluated by double integration of Boussinesq's solution. On that case the analytical integration can be executed for the radial direction but the analytical integration for the circumferential direction is impossible and the numerical integration should be considered. With the radial integration we can get non-dimensional function. Then the numerical integration for the formula is executed for the circumferential direction and the results are approximated 5th order Polynomials by using the least square method. With these 5th order approximate formula, the flexibility matrix of half-space is constructed as the coefficient matrix of nodal contact pressure by the finite element procedures. Iteration procedures are attempted by using this method to determine the separated region.

• Transactions of the Korean Society of Automotive Engineers
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• v.15 no.5
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• pp.133-138
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• 2007

Surface pitting is a major failure mode for gears. The contact fatigue life analysis of transmission gear considering running-in process is presented in this paper. Surface roughness change of rolling test is used in a life analysis. Contact stresses are obtained by contact analysis of a semi-infinite solid based on the use of influence functions; the subsurface stress field is obtained using rectangular patch solutions. Mesoscopic multiaxial fatigue criterion which can yield satisfactory results for non-proportional loading is then applied to predict fatigue damage. Suitable counting method and damage rule were used to calculate the fatigue life of random loading caused by rough surface. The life analysis considering running-in is in good agreement with the experimental results.

• Transactions of the Korean Society of Automotive Engineers
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• v.16 no.3
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• pp.137-143
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• 2008

For most bearings, it is a common requirement to have long durability. Especially wheel bearing fatigue life is the most important in automotive quality. The contact fatigue life analysis of automotive wheel bearing considering real raceway rough surface is presented in this paper. Contact stresses are obtained by contact analysis of a semi-infinite solid based on the use of influence functions; the subsurface stress field is obtained using rectangular patch solutions. Mesoscopic multiaxial fatigue criterion which can yield satisfactory results for non-proportional loading is then applied to predict fatigue damage. Suitable counting method and damage rule were used to calculate the fatigue life of random loading caused by rough surface. The life analysis considering real rough surface of wheel bearing raceway is in good agreement with the experimental results.

• Journal of Technologic Dentistry
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• v.35 no.4
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• pp.303-312
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• 2013

Purpose: In this research, non-linear three dimensional finite element models with contact elements were constructed. For the investigations of the distributions of contact stresses, 3 units fixed partial dentures model were studied, especially on the interface of the gold screw and cylinder, abutment screw. Methods: 3 types of models were constructed ; the basic fixed partial denture in molar region with 3 units and 3 implants, the intermediate pontic fixed partial denture model with 3 units and 2 implants, and the extension pontic fixed partial denture model with 3 units and 2 implants. For all types, the external loading due to chewing was simulated by applying $45^{\circ}$ linguo-buccal loading of 300 N to the medial crown. For the simulation of the clamping force which clinically occurs due to the torque, thermal expansion was provided to the cylinder as a preload. Results: Under 300 N concentrated loading to the medial crown, the maximum contact stress between abutment screw and gold screw was 86.85~175.86MPa without preload, while the maximum contact stress on the same area was 25.59~57.84MPa with preload. Conclusion: The preloading affected the outcomes of the finite element stress analysis. Reflecting the clinical conditions, the preloading conditions should be considered for other practical study utilizing FEA. For the study of the contact stresses and related motions, various conditions, such as frictional coefficient changes, gap between contact surfaces, were also varied and analyzed.